31 Matching Annotations
  1. Sep 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Bispecific Anti-Fluorescein × Anti-CD3 T-cell Engager in Combination with Fluoresceinated Adaptors Enables Lysis of AML Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13535311/
  3. Aug 2026
  4. aacrjournals.org aacrjournals.org
    Rapid Transcription Dynamics Confers Cytarabine Resistance in Acute Myeloid Leukemia
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    aacrjournals.org/bloodcancerdiscov/article/7/4/624/786176/Rapid-Transcription-Dynamics-Confers-Cytarabine
  5. Jun 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of CAR T cells Targeting a Surface RNA Binding Protein for the Treatment of Acute Leukemias
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13271017/
  7. May 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Activity of direct KRAS(G12C) inhibitors in preclinical models of pediatric cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12776615/
  9. Apr 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancement of CD117-targeted bispecific T-cell engagement by CD33-targeted bispecific T-cell co-stimulation in acute myeloid leukemia
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13114487/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nutrient Availability Dictates Cancer Metabolism–Based Therapeutic Responses to Nononcology Drugs
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    pmc.ncbi.nlm.nih.gov/articles/PMC13055633/
  12. Jan 2026
  13. www.sciencedirect.com www.sciencedirect.com
    Scaffolding-dependent CASP1 constrains excessive cell-intrinsic inflammatory signaling in leukemia
    1
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    sciencedirect.com/science/article/pii/S2451945625003952
  14. Oct 2025
  15. www.sciencedirect.com www.sciencedirect.com
    Retinoic acid and ascorbate synergize to suppress myeloid leukemia via TET2 activation
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    sciencedirect.com/science/article/pii/S2211124725011507
  16. Sep 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An isoform-specific RUNX1C–BTG2 axis governs AML quiescence and chemoresistance.
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12405853/
  18. Aug 2025
  19. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR screens identify critical targets to enhance CAR-NK cell antitumor potency
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    sciencedirect.com/science/article/pii/S1535610825003277
  20. Apr 2025
  21. aacrjournals.org aacrjournals.org
    Preclinical Development of Tuspetinib for the Treatment of Acute Myeloid Leukemia
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    aacrjournals.org/cancerrescommun/article/5/1/74/751014/Preclinical-Development-of-Tuspetinib-for-the
  22. Mar 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BKT300: A Novel Anti-Leukemic Small Molecule Targeting the Protein Regulator of Cytokinesis 1 (PRC1) Pathway
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875301/
  24. Dec 2024
  25. www.sciencedirect.com www.sciencedirect.com
    ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis
    1
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    sciencedirect.com/science/article/pii/S2211124724013391
  26. Sep 2024
  27. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17263
  28. May 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Use of Payload Binding Selectivity Enhancers to Improve Therapeutic Index of Maytansinoid-Antibody-Drug Conjugates
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10811745/
  30. Apr 2024
  31. 52.53.155.43 52.53.155.43
    Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1
    1
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    52.53.155.43/43deb73e3f715bad3d2167b3c6b37658d9cd796b/1-s2.0-S2589004224007983-main-html.html
  32. Feb 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pim kinase inhibitors increase gilteritinib cytotoxicity in FLT3-ITD acute myeloid leukemia through GSK-3β activation and c-Myc and Mcl-1 proteasomal degradation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10870818/
  34. Nov 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
    1
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    sciencedirect.com/science/article/pii/S2666379123004846
  36. Sep 2023
  37. www.sciencedirect.com www.sciencedirect.com
    PARP-1 improves leukemia outcomes by inducing parthanatos during chemotherapy
    1
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    sciencedirect.com/science/article/pii/S2666379123003580
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MET and FGFR in Relapsed or Refractory Acute Myeloid Leukemia: Preclinical and Clinical Findings, and Signal Transduction Correlates
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9992000/
  39. Mar 2023
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10466730/
  41. May 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Antigen presentation safeguards the integrity of the hematopoietic stem cell pool
    1
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    sciencedirect.com/science/article/pii/S1934590922001606
  43. Apr 2022
  44. aacrjournals.org aacrjournals.org
    Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia
    1
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    aacrjournals.org/cancerdiscovery/article/12/4/1106/689604/Subversion-of-Serotonin-Receptor-Signaling-in
  45. Sep 2021
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A method for overcoming plasma protein inhibition of tyrosine kinase inhibitors
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8478262/
  47. Jun 2021
  48. www.sciencedirect.com www.sciencedirect.com
    ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia
    1
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    sciencedirect.com/science/article/pii/S1097276521003658
  49. May 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML
    1
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    sciencedirect.com/science/article/pii/S1097276521003191
  51. www.sciencedirect.com www.sciencedirect.com
    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
    1
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    sciencedirect.com/science/article/pii/S1550413121001108
  52. Apr 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
    1
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    sciencedirect.com/science/article/pii/S1535610820305419
  54. Jan 2020
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC6363389/
  56. Nov 2018
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC6427047/
  58. Nov 2017
  59. www.sciencedirect.com www.sciencedirect.com
    Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia
    1
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    sciencedirect.com/science/article/pii/S1535610817303641