106 Matching Annotations
  1. Aug 2025
  2. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70238
  3. www.sciencedirect.com www.sciencedirect.com
    Synthesis, Characterization and Antitumor Assessments of Sulfonamide-1,2,4-Triazole Compounds with EGRF inhibitory Potential: DFT Calculation, Molecular Docking, Molecular Dynamics, and MM/PBSA Approaches
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    sciencedirect.com/science/article/pii/S0022286025023968
  4. bmccancer.biomedcentral.com bmccancer.biomedcentral.com
    HACD3 promotes malignant progression of NSCLC by suppressing the MKK7/MAPK10 signaling axis
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    bmccancer.biomedcentral.com/articles/10.1186/s12885-025-14621-y
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    Dapk2 dysfunction leads to Mic60 lactylation and mitochondrial metabolic reprogramming, promoting lung cancer EGFR-TKI resistance and metastasis
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    sciencedirect.com/science/article/pii/S153458072500471X
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    A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers
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    sciencedirect.com/science/article/pii/S1535610825003101
  7. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FBXW5 Promotes Epithelial-Mesenchymal Transition in Lung Adenocarcinoma Through the KLF13/TROAP Signaling Pathway
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    onlinelibrary.wiley.com/doi/full/10.1002/mc.70018
  8. Jul 2025
  9. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70096
  10. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Prediction of Lung Cancer Metastasis Risk Based on Single-Cell Metabolic Profiling of Circulating Tumor Cells
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202508878
  11. Jun 2025
  12. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Splicing Shift of RAC1 Accelerates Tumorigenesis and Defines a Potent Therapeutic Target in Lung Cancer
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202503322
  13. 52.53.155.43 52.53.155.43
    1-s2.0-S155608642500766X-main-html.html
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    52.53.155.43/948e09910b1ed27c4203114717163170d10423c7/1-s2.0-S155608642500766X-main-html.html
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cathepsin C correlates with M2 macrophage infiltration and regulates the tumor growth and metastasis in non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12139067/
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    Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation
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    sciencedirect.com/science/article/pii/S2451945625001667
  16. May 2025
  17. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    FAT1 Enhances the Sensitivity of Non-Small Cell Lung Cancer to VCP Inhibitors by Regulating the Activation of the Endoplasmic Reticulum Stress Pathway
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202500097RR
  18. www.sciencedirect.com www.sciencedirect.com
    hnRNPA2B1 potentiates the immune escape of non-small cell lung cancer by accelerating tumor microenvironment acidification
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    sciencedirect.com/science/article/pii/S0891584925006781
  19. Apr 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004225006480-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC12063144/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EFTUD2 is a promising diagnostic and prognostic indicator involved in the tumor immune microenvironment and glycolysis of lung adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11996642/
  22. www.sciencedirect.com www.sciencedirect.com
    Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity
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    sciencedirect.com/science/article/pii/S0092867425002909
  23. Mar 2025
  24. www.sciencedirect.com www.sciencedirect.com
    Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S1097276525001947
  25. Feb 2025
  26. aacrjournals.org aacrjournals.org
    TGF-β antagonizes IFN-γ-mediated adaptive immune evasion via activation of the AKT-Smad3-SHP1 axis in lung adenocarcinoma
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    aacrjournals.org/cancerres/article/83/13/2262/727433/TGF-Antagonizes-IFN-Mediated-Adaptive-Immune
  27. Jan 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NRP1 overexpression potentially enhances osimertinib resistance in NSCLC via activation of the PI3K/AKT signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11711526/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intratumor heterogeneity of EGFR expression mediates targeted therapy resistance and formation of drug tolerant microenvironment
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    pmc.ncbi.nlm.nih.gov/articles/PMC11695629/
  30. www.sciencedirect.com www.sciencedirect.com
    Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation
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    sciencedirect.com/science/article/pii/S1074761324005685
  31. Dec 2024
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pericytes Modulate Third‐Generation Tyrosine Kinase Inhibitor Sensitivity in EGFR‐Mutated Lung Cancer Cells Through IL32‐β5‐Integrin Paracrine Signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC11633494/
  33. www.sciencedirect.com www.sciencedirect.com
    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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    sciencedirect.com/science/article/pii/S235239642400495X
  34. Sep 2024
  35. www.nature.com www.nature.com
    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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    nature.com/articles/s41467-024-51831-7
  36. www.sciencedirect.com www.sciencedirect.com
    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
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    sciencedirect.com/science/article/pii/S2666379124004245
  37. Aug 2024
  38. www.pnas.org www.pnas.org
    Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer
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    pnas.org/doi/10.1073/pnas.2319429121
  39. aacrjournals.org aacrjournals.org
    MTX-13, a novel PTK7-directed antibody-drug conjugate with widened therapeutic index shows sustained tumor regressions for a broader spectrum of PTK7-positive tumors
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    aacrjournals.org/mct/article/22/10/1128/729312/MTX-13-a-Novel-PTK7-Directed-Antibody-Drug
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blockade of STAT3/IL-4 overcomes EGFR T790M-cis-L792F-induced resistance to osimertinib via suppressing M2 macrophages polarization
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    ncbi.nlm.nih.gov/pmc/articles/PMC9358434/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myeloid cell differentiation-related gene signature for predicting clinical outcome, immune microenvironment, and treatment response in lung adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11286868/
  42. Jul 2024
  43. www.sciencedirect.com www.sciencedirect.com
    Incense-burning smoke ingredient Auramine enhances lincRNA-p21 expression for chemosensitization in p53-mutated non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S0304389424016844
  44. Jun 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Morphological basis of the lung adenocarcinoma subtypes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11066476/
  46. www.sciencedirect.com www.sciencedirect.com
    Accelerated drug-resistant variant discovery with an enhanced, scalable mutagenic base editor platform
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    sciencedirect.com/science/article/pii/S2211124724006417
  47. May 2024
  48. aacrjournals.org aacrjournals.org
    Discovery of a novel potent EGFR inhibitor against EGFR activating mutations and on-target resistance in NSCLC
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    aacrjournals.org/clincancerres/article/30/8/1582/742134/Discovery-of-a-Novel-Potent-EGFR-Inhibitor-Against
  49. aacrjournals.org aacrjournals.org
    TNFRSF19 within the 13q12.12 risk locus functions as a lung cancer suppressor by binding Wnt3a to inhibit Wnt/β-catenin signaling.
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    aacrjournals.org/mcr/article/22/3/227/734703/TNFRSF19-within-the-13q12-12-Risk-Locus-Functions
  50. Apr 2024
  51. aacrjournals.org aacrjournals.org
    EGFR-driven lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth
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    aacrjournals.org/cancerdiscovery/article/14/3/524/734906/EGFR-Driven-Lung-Adenocarcinomas-Co-opt-Alveolar
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Omics Analysis Identifies CCR6 as a Therapeutic Target to Overcome Cancer Resistance to EGFR Inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10972824/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-17 induces NSCLC cell migration and invasion by elevating MMP19 gene transcription and expression through the interaction of p300-dependent STAT3-K631 acetylation and its Y705-phosphorylation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10972722/
  54. Mar 2024
  55. www.sciencedirect.com www.sciencedirect.com
    A single-cell characterised signature integrating heterogeneity and microenvironment of lung adenocarcinoma for prognostic stratification
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    sciencedirect.com/science/article/pii/S2352396424001270
  56. www.sciencedirect.com www.sciencedirect.com
    Silibinin is a suppressor of the metastasis-promoting transcription factor ID3
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    sciencedirect.com/science/article/pii/S0944711324001570
  57. Feb 2024
  58. 52.53.155.43 52.53.155.43
    d4-html.html
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    52.53.155.43/f092aa63506937030df3074397696edbfe46ccc6/d4-html.html
  59. www.sciencedirect.com www.sciencedirect.com
    Sialyltransferase ST3GAL4 confers osimertinib resistance and offers strategies to overcome resistance in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S0304383524001551
  60. www.biorxiv.org www.biorxiv.org
    Saturation resistance profiling of EGFR variants against tyrosine kinase inhibitors using prime editing
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    biorxiv.org/content/10.1101/2023.12.03.569825v1
  61. Jan 2024
  62. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13564
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ modeling of acquired resistance to RTK/RAS pathway targeted therapies
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    ncbi.nlm.nih.gov/pmc/articles/PMC10788224/
  64. Dec 2023
  65. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Integrative analyses of N6-methyladenosine-associated single-nucleotide polymorphisms (m6A-SNPs) identify tumor suppressor gene AK9 in lung cancer
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    onlinelibrary.wiley.com/doi/10.1002/mc.23669
  66. Nov 2023
  67. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34783
  68. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Chen - Identification of arnicolide C as a novel chemosensitizer to suppress mTOR E2F1-html.html
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    52.53.155.43/fa9809949a94f3d698a02ed4d13d532c010d3e91/British J Pharmacology - 2023 - Chen - Identification of arnicolide C as a novel chemosensitizer to suppress mTOR E2F1-html.html
  69. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13505
  70. Oct 2023
  71. www.cell.com www.cell.com
    PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C
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    cell.com/cell-reports/fulltext/S2211-1247(23)01052-5
  72. Sep 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AMT-562, a novel HER3-targeting antibody drug conjugate, demonstrates a potential to broaden therapeutic opportunities for HER3-expressing tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10477830/
  74. Aug 2023
  75. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.16933
  76. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
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    52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
  77. 52.53.155.43 52.53.155.43
    Contrast-enhanced ultrasound imaging for monitoring the efficacy of near-infrared photoimmunotherapy
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    52.53.155.43/6d717b39cddc6e562c4d653f38b90ec6204230d2/PIIS235239642300302X-html.html
  78. www.sciencedirect.com www.sciencedirect.com
    Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer
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    sciencedirect.com/science/article/pii/S1535610823002453
  79. Jul 2023
  80. 52.53.155.43 52.53.155.43
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  81. 52.53.155.43 52.53.155.43
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  82. www.sciencedirect.com www.sciencedirect.com
    The combination of osimertinib with Raf inhibitor overcomes osimertinib resistance induced by KRAS amplification in EGFR-mutated lung cancer cells
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    sciencedirect.com/science/article/pii/S0014482723002707
  83. Jun 2023
  84. 52.53.155.43 52.53.155.43
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  85. 52.53.155.43 52.53.155.43
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  86. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Prognostic impact of LILRB4 expression on tumor-infiltrating cells in resected non-small cell lung cancer
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    onlinelibrary.wiley.com/doi/10.1111/1759-7714.14991
  87. aacrjournals.org aacrjournals.org
    RBM10 loss promotes EGFR-driven lung cancer and confers sensitivity to spliceosome inhibition
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    aacrjournals.org/cancerres/article/83/9/1490/726058/RBM10-Loss-Promotes-EGFR-Driven-Lung-Cancer-and
  88. May 2023
  89. aacrjournals.org aacrjournals.org
    Decoding the lncRNAome across diverse cellular stresses reveals core p53-effector pan-cancer suppressive lncRNAs
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    aacrjournals.org/cancerrescommun/article/3/5/842/726358/Decoding-the-lncRNAome-Across-Diverse-Cellular
  90. Apr 2023
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAB27B Drives a Cancer Stem Cell Phenotype in NSCLC Cells Through Enhanced Extracellular Vesicle Secretion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10109210/
  92. Mar 2023
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmaceutical Reactivation of Attenuated Apoptotic Pathways Leads to Elimination of Osimertinib Drug-Tolerant Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10035388/
  94. Feb 2023
  95. www.sciencedirect.com www.sciencedirect.com
    Protocol for cell-type-specific tissue reconstruction in the murine lung fibrogenic microenvironment
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    sciencedirect.com/science/article/pii/S266616672200898X
  96. Dec 2022
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome Editing Is Induced in a Binary Manner in Single Human Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9722467/
  98. aacrjournals.org aacrjournals.org
    TFAP4 activates IGF2BP1 and promotes progression of non-small cell lung cancer by stabilizing TK1 expression through m6A modification
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    aacrjournals.org/mcr/article/20/12/1763/711001/TFAP4-Activates-IGF2BP1-and-Promotes-Progression
  99. Sep 2022
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pan-Cancer Analysis and Experimental Validation Identify ACOT7 as a Novel Oncogene and Potential Therapeutic Target in Lung Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9497106/
  101. Aug 2022
  102. www.sciencedirect.com www.sciencedirect.com
    Lung fibrogenic microenvironment in mouse reconstitutes human alveolar structure and lung tumor
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    sciencedirect.com/science/article/pii/S2589004222011841
  103. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cancer-associated fibroblasts in nonsmall cell lung cancer: From molecular mechanisms to clinical implications
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34127
  104. Jul 2022
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EGFR inhibition enhances the cellular uptake and antitumor-activity of the HER3 antibody drug conjugate HER3-DXd
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    ncbi.nlm.nih.gov/pmc/articles/PMC8732289/
  106. Jun 2022
  107. www.sciencedirect.com www.sciencedirect.com
    Endogenous spacing enables co-processing of microRNAs and efficient combinatorial RNAi
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    sciencedirect.com/science/article/pii/S2667237522001084
  108. May 2022
  109. www.sciencedirect.com www.sciencedirect.com
    ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1
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    sciencedirect.com/science/article/pii/S1097276522004348
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The oncoprotein BCL6 enables solid tumor cells to evade genotoxic stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC9064299/
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Picropodophyllin inhibits the growth of pemetrexed-resistant malignant pleural mesothelioma via microtubule inhibition and IGF-1R-, caspase-independent pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC9073748/
  112. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Annexin A2: The Diversity of Pathological Effects in Tumorigenesis and Immune Response
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34048
  113. Apr 2022
  114. www.sciencedirect.com www.sciencedirect.com
    Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
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    sciencedirect.com/science/article/pii/S2211124722003886
  115. Dec 2021
  116. elifesciences.org elifesciences.org
    Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology
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  117. Sep 2021
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Silibinin Suppresses Tumor Cell-Intrinsic Resistance to Nintedanib and Enhances Its Clinical Activity in Lung Cancer
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  119. Aug 2021
  120. www.sciencedirect.com www.sciencedirect.com
    Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis
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    Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies
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    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
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  123. Jul 2021
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    The Cancer SENESCopedia: A delineation of cancer cell senescence
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  125. May 2021
  126. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Urinary malate dehydrogenase 2 is a new biomarker for early detection of non-small-cell lung cancer
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    Near-infrared photoimmunotherapy targeting GPR87: Development of a humanised anti-GPR87 mAb and therapeutic efficacy on a lung cancer mouse model
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    CloneSeq: A highly sensitive analysis platform for the characterization of 3D-cultured single-cell-derived clones
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  129. mcr.aacrjournals.org mcr.aacrjournals.org
    Exosomal Delivery of FTO Confers Gefitinib Resistance to Recipient Cells through ABCC10 Regulation in an m6A-dependent Manner
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  130. Apr 2021
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    Non-canonical Glutamate-Cysteine Ligase Activity Protects against Ferroptosis
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  132. Mar 2021
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    Alisertib inhibits migration and invasion of EGFR-TKI resistant cells by partially reversing the epithelial-mesenchymal transition
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  134. Sep 2020
  135. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Marked synergy by vertical inhibition of EGFR signaling in NSCLC spheroids shows SOS1 is a therapeutic target in EGFR-mutated cancer
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    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway
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    Senescence, Necrosis, and Apoptosis Govern Circulating Cell-free DNA Release Kinetics
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  138. Jan 2020
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    miR-762 activation confers acquired resistance to gefitinib in non-small cell lung cancer
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    The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase
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  141. Nov 2018
  142. bmccancer.biomedcentral.com bmccancer.biomedcentral.com
    p300 promotes proliferation, migration, and invasion via inducing epithelial-mesenchymal transition in non-small cell lung cancer cells
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  143. Nov 2017
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    TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells
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    Complement Component 3 Adapts the Cerebrospinal Fluid for Leptomeningeal Metastasis
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