59 Matching Annotations
  1. Last 7 days
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    HDAC5 depletion promotes hyper-acetylation of FOXA1 and potentiates HIF1α transcriptional activation in pancreatic cancer
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    sciencedirect.com/science/article/pii/S1097276526004119
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibiting Fatty Acid Oxidation Reverses Autophagy-Mediated Acquired Chemotherapy Resistance in Pancreatic Ductal Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13324344/
  4. Jun 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A malignant subpopulation of H2AFZ+ cells interacts with myeloid cells to promote an anti-inflammatory microenvironment and drive hepatic metastasis, revealing an immunotherapeutic strategy for pancreatic ductal adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13266339/
  6. May 2026
  7. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Tumor-Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202520029
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combining ferroptosis inducers with gemcitabine to enhance treatment efficacy in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13185238/
  9. Apr 2026
  10. www.biorxiv.org www.biorxiv.org
    Mutant KRAS promotes NF-κB driven CCL20 chemokine expression in pancreatic ductal adenocarcinoma
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    biorxiv.org/content/10.64898/2026.04.13.717530v1
  11. Mar 2026
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    Targeting the ferritinophagy-lysosome axis as a therapeutic vulnerability in gastroenteropancreatic neuroendocrine tumors
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    sciencedirect.com/science/article/pii/S2666379126001126
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    Cancer cell-derived sialylated IgG interacting with Siglec-7/9/10 is a potential immunotherapeutic target in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2666379126000777
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    DPP4 suppresses pancreatic cancer growth by enhancing ferroptosis sensitivity through stabilization of ACSL4
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    sciencedirect.com/science/article/pii/S0898656826000963
  15. Feb 2026
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    Syndecan-1-targeted therapeutic antibody impairs macropinocytosis and elicits antitumor immunity in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2666379126000303
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Supplemental_Material.pdf
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    pmc.ncbi.nlm.nih.gov/articles/instance/12863058/bin/Supplemental_Material.pdf
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Lysine Demethylase KDM4C is an Oncogenic Driver and Regulates ERK Activity in KRAS Mutant Pancreatic Ductal Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12856980/
  19. Dec 2025
  20. www.nature.com www.nature.com
    RASH3D19 mediates RAS activation through a positive feedback loop in KRAS-mutant cancer
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    nature.com/articles/s41556-025-01816-5
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IFN-γ-driven UBE2D3 upregulation impairs antigen presentation pathways and anti-tumor immunity in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12663187/
  22. Nov 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12594208/
  24. 54.241.53.176 54.241.53.176
    2025.11.06.687028v2.full-html.html
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    OCIAD2-IQGAP1 interaction promotes pancreatic cancer progression by suppressing oxidative stress and mitochondria-mediated apoptosis
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    sciencedirect.com/science/article/pii/S0898656825006321
  26. Oct 2025
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    Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas
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    sciencedirect.com/science/article/pii/S2211124725012586
  28. Sep 2025
  29. www.biorxiv.org www.biorxiv.org
    BOGO: A Proteome-Wide Gene Overexpression Platform for Discovering Rational Cancer Combination Therapies
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    biorxiv.org/content/10.1101/2025.09.02.673780v1
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    Phosphatidylserine-positive extracellular vesicles for detecting multiple operable cancers
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    sciencedirect.com/science/article/pii/S2211124725010307
  31. Aug 2025
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PI5P4Kα promotes glucose and iron acquisition to support metabolic fitness in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12622763/
  33. journals.sagepub.com journals.sagepub.com
    The role of formin-like protein 1 in pancreatic cancer and its specific effects on immunity
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    journals.sagepub.com/doi/full/10.1177/03000605251365844
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
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    A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers
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    sciencedirect.com/science/article/pii/S1535610825003101
  36. Jul 2025
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel defined manganese metabolism‑related gene signature for predicting the prognosis of pancreatic ductal adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12282324/
  38. May 2025
  39. www.sciencedirect.com www.sciencedirect.com
    ILF3 mediates lipid metabolism to promote pancreatic cancer development by regulating CPT1A-activated PPARa signaling pathway
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    sciencedirect.com/science/article/pii/S0925443925002674
  40. Apr 2025
  41. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    PPY-Induced iCAFs Cultivate an Immunosuppressive Microenvironment in Pancreatic Cancer
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202413432
  42. Oct 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CALB2 drives pancreatic cancer metastasis through inflammatory reprogramming of the tumor microenvironment
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    ncbi.nlm.nih.gov/pmc/articles/PMC11448066/
  44. May 2024
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Janus kinase 1 is critical for pancreatic cancer initiation and progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11194014/
  46. Apr 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BUB1 Promotes Gemcitabine Resistance in Pancreatic Cancer Cells by Inhibiting Ferroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11048608/
  48. Feb 2024
  49. 52.53.155.43 52.53.155.43
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    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
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    sciencedirect.com/science/article/pii/S2666379124000570
  51. Jan 2024
  52. www.mdpi.com www.mdpi.com
    Multi-Algorithm Analysis Reveals Pyroptosis-Linked Genes as Pancreatic Cancer Biomarkers
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    mdpi.com/2072-6694/16/2/372
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vitamin B6 competition in the tumor microenvironment hampers antitumor functions of NK cells.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10784745/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Machine learning algorithm integrates bulk and single-cell transcriptome sequencing to reveal immune-related personalized therapy prediction features for pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10756117/
  55. Oct 2023
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Targeting of NAD Biosynthesis and the NAD-dependent Transcription Factor C-terminal Binding Protein as a Promising Novel Therapy for Pancreatic Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10549224/
  57. Sep 2023
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant KRAS Mediates circARFGEF2 Biogenesis to Promote Lymphatic Metastasis of Pancreatic Ductal Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10502454/
  59. Aug 2023
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10463307/
  61. Jul 2023
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The MyD88 inhibitor, ST2825, induces cell cycle arrest and apoptosis by suppressing the activation of the NF‑κB/AKT1/p21 pathway in pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10308493/
  63. May 2023
  64. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13442
  65. Apr 2023
  66. www.sciencedirect.com www.sciencedirect.com
    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
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    sciencedirect.com/science/article/pii/S2666379123001179
  67. Dec 2022
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDB2 represses epithelial-to-mesenchymal transition and sensitizes pancreatic ductal adenocarcinoma cells to chemotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC9773984/
  69. www.cell.com www.cell.com
    Fluorinated triphenylphosphonium analogs improve cell selectivity and in vivo detection of mito-metformin
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    cell.com/iscience/abstract/S2589-0042(22)01942-3
  70. Aug 2022
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Concurrent inhibition of IGF1R and ERK increases pancreatic cancer sensitivity to autophagy inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC8886214/
  72. Jul 2022
  73. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Exploring the potential of exosomes in diagnosis and drug delivery for PDAC
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34195
  74. Apr 2022
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UHMK1 Is a Novel Marker for Personalized Prediction of Pancreatic Cancer Prognosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8960145/
  76. Jan 2022
  77. www.sciencedirect.com www.sciencedirect.com
    Mechanosensitive Channel Piezo1 Induces Cell Apoptosis in Pancreatic Cancer by Ultrasound with Microbubbles
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    sciencedirect.com/science/article/pii/S2589004222000037
  78. Jul 2021
  79. www.sciencedirect.com www.sciencedirect.com
    DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters
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    sciencedirect.com/science/article/pii/S221112471931527X
  80. www.sciencedirect.com www.sciencedirect.com
    Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis
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    sciencedirect.com/science/article/pii/S1534580719304204
  81. Jun 2021
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-PanIN-seq unveils that ARID1A deficiency promotes pancreatic tumorigenesis by attenuating KRAS-induced senescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC8203294/
  83. Mar 2021
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sulforaphane Inhibits the Expression of Long Noncoding RNA H19 and Its Target APOBEC3G and Thereby Pancreatic Cancer Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC7920255/
  85. Sep 2020
  86. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Long noncoding RNA SOX2OT promotes the proliferation of pancreatic cancer by binding to FUS
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32827
  87. elifesciences.org elifesciences.org
    HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties
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    elifesciences.org/articles/33947
  88. www.mdpi.com www.mdpi.com
    Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics’ Machinery in Pancreas Cancer Cells
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    mdpi.com/2072-6694/12/6/1643
  89. Jan 2020
  90. www.sciencedirect.com www.sciencedirect.com
    High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells
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    sciencedirect.com/science/article/pii/S1550413119300695
  91. www.sciencedirect.com www.sciencedirect.com
    Rigidity controls human desmoplastic matrix anisotropy to enable pancreatic cancer cell spread via extracellular signal-regulated kinase 2
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    sciencedirect.com/science/article/pii/S0945053X18302841
  92. Nov 2018
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6122955/
  94. Nov 2017
  95. www.sciencedirect.com www.sciencedirect.com
    Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
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    sciencedirect.com/science/article/pii/S109727651730312X