47 Matching Annotations
  1. Dec 2025
  2. www.nature.com www.nature.com
    RASH3D19 mediates RAS activation through a positive feedback loop in KRAS-mutant cancer
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    nature.com/articles/s41556-025-01816-5
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IFN-γ-driven UBE2D3 upregulation impairs antigen presentation pathways and anti-tumor immunity in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12663187/
  4. Nov 2025
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12594208/
  6. 54.241.53.176 54.241.53.176
    2025.11.06.687028v2.full-html.html
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    54.241.53.176/c5747531de041288b038c2a31e89061fc2d84331/2025.11.06.687028v2.full-html.html
  7. www.sciencedirect.com www.sciencedirect.com
    OCIAD2-IQGAP1 interaction promotes pancreatic cancer progression by suppressing oxidative stress and mitochondria-mediated apoptosis
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    sciencedirect.com/science/article/pii/S0898656825006321
  8. Oct 2025
  9. www.sciencedirect.com www.sciencedirect.com
    Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas
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    sciencedirect.com/science/article/pii/S2211124725012586
  10. Sep 2025
  11. www.biorxiv.org www.biorxiv.org
    BOGO: A Proteome-Wide Gene Overexpression Platform for Discovering Rational Cancer Combination Therapies
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    biorxiv.org/content/10.1101/2025.09.02.673780v1
  12. www.sciencedirect.com www.sciencedirect.com
    Phosphatidylserine-positive extracellular vesicles for detecting multiple operable cancers
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    sciencedirect.com/science/article/pii/S2211124725010307
  13. Aug 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PI5P4Kα promotes glucose and iron acquisition to support metabolic fitness in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12622763/
  15. journals.sagepub.com journals.sagepub.com
    The role of formin-like protein 1 in pancreatic cancer and its specific effects on immunity
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    journals.sagepub.com/doi/full/10.1177/03000605251365844
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
  17. www.sciencedirect.com www.sciencedirect.com
    A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers
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    sciencedirect.com/science/article/pii/S1535610825003101
  18. Jul 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel defined manganese metabolism‑related gene signature for predicting the prognosis of pancreatic ductal adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12282324/
  20. May 2025
  21. www.sciencedirect.com www.sciencedirect.com
    ILF3 mediates lipid metabolism to promote pancreatic cancer development by regulating CPT1A-activated PPARa signaling pathway
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    sciencedirect.com/science/article/pii/S0925443925002674
  22. Apr 2025
  23. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    PPY-Induced iCAFs Cultivate an Immunosuppressive Microenvironment in Pancreatic Cancer
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202413432
  24. Oct 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CALB2 drives pancreatic cancer metastasis through inflammatory reprogramming of the tumor microenvironment
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    ncbi.nlm.nih.gov/pmc/articles/PMC11448066/
  26. May 2024
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Janus kinase 1 is critical for pancreatic cancer initiation and progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11194014/
  28. Apr 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BUB1 Promotes Gemcitabine Resistance in Pancreatic Cancer Cells by Inhibiting Ferroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11048608/
  30. Feb 2024
  31. 52.53.155.43 52.53.155.43
    176-html.html
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  32. www.sciencedirect.com www.sciencedirect.com
    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
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    sciencedirect.com/science/article/pii/S2666379124000570
  33. Jan 2024
  34. www.mdpi.com www.mdpi.com
    Multi-Algorithm Analysis Reveals Pyroptosis-Linked Genes as Pancreatic Cancer Biomarkers
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    mdpi.com/2072-6694/16/2/372
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vitamin B6 competition in the tumor microenvironment hampers antitumor functions of NK cells.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10784745/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Machine learning algorithm integrates bulk and single-cell transcriptome sequencing to reveal immune-related personalized therapy prediction features for pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10756117/
  37. Oct 2023
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Targeting of NAD Biosynthesis and the NAD-dependent Transcription Factor C-terminal Binding Protein as a Promising Novel Therapy for Pancreatic Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10549224/
  39. Sep 2023
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant KRAS Mediates circARFGEF2 Biogenesis to Promote Lymphatic Metastasis of Pancreatic Ductal Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10502454/
  41. Aug 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10463307/
  43. Jul 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The MyD88 inhibitor, ST2825, induces cell cycle arrest and apoptosis by suppressing the activation of the NF‑κB/AKT1/p21 pathway in pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10308493/
  45. May 2023
  46. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13442
  47. Apr 2023
  48. www.sciencedirect.com www.sciencedirect.com
    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
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    sciencedirect.com/science/article/pii/S2666379123001179
  49. Dec 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDB2 represses epithelial-to-mesenchymal transition and sensitizes pancreatic ductal adenocarcinoma cells to chemotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC9773984/
  51. www.cell.com www.cell.com
    Fluorinated triphenylphosphonium analogs improve cell selectivity and in vivo detection of mito-metformin
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    cell.com/iscience/abstract/S2589-0042(22)01942-3
  52. Aug 2022
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Concurrent inhibition of IGF1R and ERK increases pancreatic cancer sensitivity to autophagy inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC8886214/
  54. Jul 2022
  55. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Exploring the potential of exosomes in diagnosis and drug delivery for PDAC
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34195
  56. Apr 2022
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UHMK1 Is a Novel Marker for Personalized Prediction of Pancreatic Cancer Prognosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8960145/
  58. Jan 2022
  59. www.sciencedirect.com www.sciencedirect.com
    Mechanosensitive Channel Piezo1 Induces Cell Apoptosis in Pancreatic Cancer by Ultrasound with Microbubbles
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    sciencedirect.com/science/article/pii/S2589004222000037
  60. Jul 2021
  61. www.sciencedirect.com www.sciencedirect.com
    DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters
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    sciencedirect.com/science/article/pii/S221112471931527X
  62. www.sciencedirect.com www.sciencedirect.com
    Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis
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    sciencedirect.com/science/article/pii/S1534580719304204
  63. Jun 2021
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-PanIN-seq unveils that ARID1A deficiency promotes pancreatic tumorigenesis by attenuating KRAS-induced senescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC8203294/
  65. Mar 2021
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sulforaphane Inhibits the Expression of Long Noncoding RNA H19 and Its Target APOBEC3G and Thereby Pancreatic Cancer Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC7920255/
  67. Sep 2020
  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Long noncoding RNA SOX2OT promotes the proliferation of pancreatic cancer by binding to FUS
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32827
  69. elifesciences.org elifesciences.org
    HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties
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    elifesciences.org/articles/33947
  70. www.mdpi.com www.mdpi.com
    Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics’ Machinery in Pancreas Cancer Cells
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    mdpi.com/2072-6694/12/6/1643
  71. Jan 2020
  72. www.sciencedirect.com www.sciencedirect.com
    High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells
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    sciencedirect.com/science/article/pii/S1550413119300695
  73. www.sciencedirect.com www.sciencedirect.com
    Rigidity controls human desmoplastic matrix anisotropy to enable pancreatic cancer cell spread via extracellular signal-regulated kinase 2
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    sciencedirect.com/science/article/pii/S0945053X18302841
  74. Nov 2018
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6122955/
  76. Nov 2017
  77. www.sciencedirect.com www.sciencedirect.com
    Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
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    sciencedirect.com/science/article/pii/S109727651730312X