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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Molecular basis for shifted receptor recognition by an encephalitic arbovirus

1
1. scibot 06 Sep 2025
  
  in Public
  
  RRID:CVCL_D615
  
  DOI: 10.1016/j.cell.2025.03.029
  
  Resource: (RRID:CVCL_D615)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12406711/
Aug 2025
www.sciencedirect.com www.sciencedirect.com

Clonotype-enriched somatic hypermutations drive affinity maturation of a public human antibody targeting an occluded sarbecovirus epitope

1
1. scibot 13 Aug 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.celrep.2025.116122
  
  Resource: (RRID:CVCL_D615)
  
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sciencedirect.com/science/article/pii/S2211124725008939
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Merbecovirus S2 subunit vaccines elicit cross reactive antibodies and provide partial protection against MERS coronavirus

1
1. scibot 01 Aug 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1038/s44298-025-00142-9
  
  Resource: (RRID:CVCL_D615)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12307638/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Neprilysin 2 catalyses the degradation of natriuretic peptides despite sacubitrilat Inhibition

1
1. scibot 31 Jul 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1038/s41598-025-10166-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12304097/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ST2/IL-33 axis blockade inhibits regulatory T cell cytotoxicity towards CD8 T cells in the leukemic niche

1
1. scibot 25 Jul 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1038/s41467-025-61647-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12279971/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Dual targeting of tumoral cells and immune microenvironment by blocking the IL-33/IL1RL1 pathway

1
1. scibot 17 Jul 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1038/s41467-025-61567-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12259856/
www.sciencedirect.com www.sciencedirect.com

Proximity between LAG-3 and the T cell receptor guides suppression of T cell activation and autoimmunity

1
1. scibot 15 Jul 2025
  
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  RRID: CVCL_D615
  
  DOI: 10.1016/j.cell.2025.06.004
  
  Resource: (RRID:CVCL_D615)
  
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sciencedirect.com/science/article/pii/S0092867425006385
www.biorxiv.org www.biorxiv.org

Single administration of mosaic-8b RBD-nanoparticle vaccine prepared with atomic layer deposition technology elicits broadly neutralizing anti-sarbecovirus responses

1
1. scibot 12 Jul 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1101/2025.06.16.660007
  
  Resource: (RRID:CVCL_D615)
  
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biorxiv.org/content/10.1101/2025.06.16.660007v1
www.sciencedirect.com www.sciencedirect.com

Structural and functional insights into the evolution of SARS-CoV-2 KP.3.1.1 spike protein

1
1. scibot 08 Jul 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.celrep.2025.115941
  
  Resource: (RRID:CVCL_D615)
  
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sciencedirect.com/science/article/pii/S2211124725007120
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Antibody durability is influenced by interleukin-2 production by undifferentiated memory T helper cells and extensive B cell clonal expansion

1
1. scibot 02 Jul 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.celrep.2025.115934
  
  Resource: (RRID:CVCL_D615)
  
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sciencedirect.com/science/article/pii/S2211124725007053
www.biorxiv.org www.biorxiv.org

Cetuximab increases LGR5 expression and augments LGR5-targeting antibody-drug conjugate efficacy in patient-derived colorectal cancer models

1
1. scibot 01 Jul 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1101/2025.06.18.660406
  
  Resource: (RRID:CVCL_D615)
  
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biorxiv.org/content/10.1101/2025.06.18.660406v1
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic E. coli UTI

1
1. scibot 25 Jun 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1126/sciadv.adw0698
  
  Resource: (RRID:CVCL_D615)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12180514/
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

An amphipol-stabilized multi-pass transmembrane protein as an immunogen to generate mouse memory B cells against native VMAT2

1
1. scibot 22 Jun 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1002/1873-3468.70092
  
  Resource: (RRID:CVCL_D615)
  
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  SciCrunch record: RRID:CVCL_D615
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70092
52.53.155.43 52.53.155.43

PDF-html.html

2
1. scibot 14 Jun 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1158/1535-7163.mct-24-0846
  
  Resource: (RRID:CVCL_D615)
  
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  SciCrunch record: RRID:CVCL_D615
  
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  RRID:CVCL_D615
2. scibot 11 Jun 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1158/1535-7163.mct-24-0846
  
  Resource: (RRID:CVCL_D615)
  
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52.53.155.43/36bef4761a687f6ee5c6cf9f652510edad253d31/PDF-html.html
www.science.org www.science.org

Nonstabilized SARS-CoV-2 spike mRNA vaccination induces broadly neutralizing antibodies in nonhuman primates

1
1. scibot 14 Jun 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1126/scitranslmed.adn5651
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
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science.org/doi/10.1126/scitranslmed.adn5651
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The tetravalent, bispecific properties of FS118, an anti-LAG-3/PD-L1 antibody, mediate LAG-3 shedding from CD4+ and CD8+ tumor-infiltrating lymphocytes

1
1. scibot 19 May 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1097/CAD.0000000000001705
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_D615
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12061380/
www.sciencedirect.com www.sciencedirect.com

Nanoparticle-formulated mRNA encoding engineered multivalent SIRPα-Fc fusion proteins shows robust anti-cancer activity in preclinical models

1
1. scibot 18 May 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.omtn.2025.102550
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_D615
  
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  RRID:CVCL_D615
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sciencedirect.com/science/article/pii/S2162253125001040
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

1-s2.0-S2589004225006479-main-html.html

4
1. scibot 12 Apr 2025
  
  in Public
  
  CVCL_D615
  
  DOI: 10.1016/j.isci.2025.112386
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_D615
  
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  RRID:CVCL_D615
2. scibot 12 Apr 2025
  
  in Public
  
  RRID:CLCL_D615
  
  DOI: 10.1016/j.isci.2025.112386
  
  Resource: None
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:CVCL_D615
  
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  RRIDCUR:Unresolved RRID:CVCL_D615
3. scibot 10 Apr 2025
  
  in Public
  
  CVCL_D615
  
  DOI: 10.1016/j.isci.2025.112386
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_D615
  
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  RRID:CVCL_D615
4. scibot 10 Apr 2025
  
  in Public
  
  RRID:CLCL_D615
  
  DOI: 10.1016/j.isci.2025.112386
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_D615
  
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  RRID:CVCL_D615 RRIDCUR:Unresolved
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RRIDCUR:Unresolved

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pmc.ncbi.nlm.nih.gov/articles/PMC12052844/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Molecular basis for shifted receptor recognition by an encephalitic arbovirus

1
1. scibot 05 Apr 2025
  
  in Public
  
  RRID:CVCL_D615
  
  DOI: 10.1016/j.cell.2025.03.029
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12406711/
www.sciencedirect.com www.sciencedirect.com

Structural basis for plasticity in receptor engagement by an encephalitic alphavirus

1
1. scibot 05 Apr 2025
  
  in Public
  
  RRID:CVCL_D615
  
  DOI: 10.1016/j.cell.2025.02.036
  
  Resource: (RRID:CVCL_D615)
  
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  RRID:CVCL_D615
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sciencedirect.com/science/article/pii/S0092867425002727
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Novel Amanitin-Based Antibody–Drug Conjugates Targeting TROP2 for the Treatment of Pancreatic Cancer

1
1. scibot 04 Apr 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1158/1535-7163.MCT-24-0266
  
  Resource: (RRID:CVCL_D615)
  
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  RRID:CVCL_D615
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pmc.ncbi.nlm.nih.gov/articles/PMC11962393/
Feb 2025
www.sciencedirect.com www.sciencedirect.com

A strain-transcending anti-AMA1 human monoclonal antibody neutralizes malaria parasites independent of direct RON2L receptor blockade

1
1. scibot 28 Feb 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.xcrm.2025.101985
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2666379125000588
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

An IgE antibody targeting HER2 identified by clonal selection restricts breast cancer growth via immune-stimulating activities

1
1. scibot 15 Feb 2025
  
  in Public
  
  RRID:CVCL_D615
  
  DOI: 10.1186/s13046-025-03319-5
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
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  RRID:CVCL_D615
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pmc.ncbi.nlm.nih.gov/articles/PMC11818027/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Broadening a SARS-CoV-1–neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution

1
1. scibot 30 Jan 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1126/scisignal.abk3516
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_D615
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11771511/
www.sciencedirect.com www.sciencedirect.com

Convergence of orphan quality control pathways at a ubiquitin chain-elongating ligase

1
1. scibot 30 Jan 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.molcel.2025.01.002
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_D615
  
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sciencedirect.com/science/article/pii/S1097276525000024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Therapeutic Targeting and Structural Characterization of a Sotorasib-Modified KRAS G12C–MHC I Complex Demonstrate the Antitumor Efficacy of Hapten-Based Strategies

1
1. scibot 25 Jan 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.1158/0008-5472.CAN-24-2450
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
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  RRID:CVCL_D615
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pmc.ncbi.nlm.nih.gov/articles/PMC11733532/
www.sciencedirect.com www.sciencedirect.com

Designed mosaic nanoparticles enhance cross-reactive immune responses in mice

1
1. scibot 24 Jan 2025
  
  in Public
  
  RRID:CVCL_D615
  
  DOI: 10.1016/j.cell.2024.12.015
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S0092867424014284
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Target-agnostic identification of human antibodies to Plasmodium falciparum sexual forms reveals cross-stage recognition of glutamate-rich repeats

1
1. scibot 18 Jan 2025
  
  in Public
  
  RRID:CVCL_D615
  
  DOI: 10.7554/eLife.97865
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11737873/
www.sciencedirect.com www.sciencedirect.com

A triad of somatic mutagenesis converges in self-reactive B cells to cause a virus-induced autoimmune disease

1
1. scibot 16 Jan 2025
  
  in Public
  
  RRID:CVCL_D615
  
  DOI: 10.1016/j.immuni.2024.12.011
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1074761324005752
www.nature.com www.nature.com

Multivalent S2 subunit vaccines provide broad protection against Clade 1 sarbecoviruses in female mice

1
1. scibot 10 Jan 2025
  
  in Public
  
  RRID:CVCL_D615
  
  DOI: 10.1038/s41467-025-55824-y
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_D615
  
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  RRID:CVCL_D615
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nature.com/articles/s41467-025-55824-y
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The co-receptor Tetraspanin12 directly captures Norrin to promote ligand-specific β-catenin signaling

1
1. scibot 04 Jan 2025
  
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  RRID:CVCL_D615
  
  DOI: 10.7554/eLife.96743
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_D615
  
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  RRID:CVCL_D615
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pmc.ncbi.nlm.nih.gov/articles/PMC11695057/
Dec 2024
52.53.155.43 52.53.155.43

mct-24-0266-html.html

1
1. scibot 24 Dec 2024
  
  in Public
  
  RRID:CVCL_D615
  
  DOI: 10.1158/1535-7163.mct-24-0266
  
  Resource: (RRID:CVCL_D615)
  
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52.53.155.43/e3c3817ac819dde6c15544fa19222c2e3fb37801/mct-24-0266-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer

1
1. scibot 21 Dec 2024
  
  in Public
  
  RRID:CVCL_D615
  
  DOI: 10.1101/2024.02.20.581056
  
  Resource: (RRID:CVCL_D615)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_D615
  
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  RRID:CVCL_D615
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pmc.ncbi.nlm.nih.gov/articles/PMC11601497/
52.53.155.43 52.53.155.43

can-24-2450-html.html

1
1. scibot 19 Dec 2024
  
  in Public
  
  RRID:CVCL_D615
  
  DOI: 10.1158/0008-5472.can-24-2450
  
  Resource: (RRID:CVCL_D615)
  
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  RRID:CVCL_D615
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52.53.155.43/eda542f05a259fcd2586bec9365306e8eda4954b/can-24-2450-html.html
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Modulating the immunodominance hierarchy of immunoglobulin germline-encoded structural motifs targeting the influenza hemagglutinin stem

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  DOI: 10.1016/j.celrep.2024.114990
  
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Comprehensive method for producing high-affinity mouse monoclonal antibodies of various isotypes against (4-hydroxy-3-nitrophenyl)acetyl (NP) hapten

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  RRID:CVCL_D615
  
  DOI: 10.1016/j.heliyon.2024.e40837
  
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sciencedirect.com/science/article/pii/S2405844024168685
Nov 2024
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Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination

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1. scibot 15 Nov 2024
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.celrep.2024.114922
  
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A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies

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1. scibot 27 Sep 2024
  
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Discovery and characterization of a pan-betacoronavirus S2-binding antibody

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1. scibot 27 Sep 2024
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.str.2024.08.022
  
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Prominin 1 and Tweety Homology 1 both induce extracellular vesicle formation

1
1. scibot 25 Sep 2024
  
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  RRID:CVCL_D615
  
  DOI: 10.7554/eLife.100061
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11405016/
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Dynamic allostery drives autocrine and paracrine TGF-β signaling

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PlexinB1 Inactivation Reprograms Immune Cells in the Tumor Microenvironment, Inhibiting Breast Cancer Growth and Metastatic Dissemination

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1. scibot 05 Sep 2024
  
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  RRID:CVCL_D615
  
  DOI: 10.1158/2326-6066.CIR-23-0289
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11369622/
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Decoupling HIV-1 antiretroviral drug inhibition from plasma antibody activity to evaluate broadly neutralizing antibody therapeutics and vaccines

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  A14528
  
  DOI: 10.1016/j.xcrm.2024.101702
  
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sciencedirect.com/science/article/pii/S2666379124004233
Aug 2024
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Application of a bespoke monoclonal antibody panel to characterize immune cell populations in cave nectar bats

1
1. scibot 30 Aug 2024
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.celrep.2024.114703
  
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Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals

1
1. scibot 28 Aug 2024
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.cell.2024.07.052
  
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An explainable language model for antibody specificity prediction using curated influenza hemagglutinin antibodies

1
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  DOI: 10.1016/j.immuni.2024.07.022
  
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Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination

1
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.xcrm.2024.101668
  
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Structural requirements for activity of Mind bomb1 in Notch signaling

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Structural basis of psychedelic LSD recognition at dopamine D1 receptor

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1. scibot 13 Aug 2024
  
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  DOI: 10.1016/j.neuron.2024.07.003
  
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The V-ATPase/ATG16L1 axis is controlled by the V1H subunit

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  DOI: 10.1016/j.molcel.2024.07.003
  
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sciencedirect.com/science/article/pii/S1097276524005793
Jul 2024
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Mapping immunodominant sites on the MERS-CoV spike glycoprotein targeted by infection-elicited antibodies in humans

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1. scibot 30 Jul 2024
  
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  Thermo FisherCat#A14635
  
  DOI: 10.1016/j.celrep.2024.114530
  
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SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition

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  Expi293F cellsGIBCOA14527
  
  DOI: 10.1016/j.molcel.2024.06.028
  
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Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5

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  RRID:CVCL_D615
  
  DOI: 10.1016/j.cell.2024.06.037
  
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Broad sarbecovirus neutralization by combined memory B cell antibodies to ancestral SARS-CoV-2

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A cryptic site in class 5 epitope of SARS-CoV-2 RBD maintains highly conservation across natural isolates

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  DOI: 10.1016/j.isci.2024.110208
  
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Small molecule inhibitor binds to NOD-like receptor family pyrin domain containing 3 and prevents inflammasome activation

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  DOI: 10.1016/j.isci.2024.110459
  
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Jun 2024
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Isolation of human antibodies against influenza B neuraminidase and mechanisms of protection at the airway interface

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  DOI: 10.1016/j.immuni.2024.05.002
  
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An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike

2
1. scibot 30 May 2024
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.celrep.2024.114265
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00593-X
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Mosaic RBD nanoparticle elicits immunodominant antibody responses across sarbecoviruses

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  DOI: 10.1016/j.celrep.2024.114235
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00563-1
Apr 2024
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Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses

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  DOI: 10.1016/j.immuni.2024.03.022
  
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XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies

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  DOI: 10.1158/1535-7163.MCT-23-0336
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10993987/
Mar 2024
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Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation

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  DOI: 10.7554/eLife.92873
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10948148/
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Frequency-potency analysis of IgG+ memory B cells delineates neutralizing antibody responses at single-cell resolution

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  RRID:CVCL_D615
  
  DOI: 10.1016/j.celrep.2024.113948
  
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Feb 2024
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Mosaic sarbecovirus vaccination elicits cross-reactive responses in pre-immunized animals

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  DOI: 10.1101/2024.02.08.576722
  
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biorxiv.org/content/10.1101/2024.02.08.576722v1
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Effector functions are required for broad and potent protection of neonatal mice with antibodies targeting HSV glycoprotein D

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  DOI: 10.1016/j.xcrm.2024.101417
  
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sciencedirect.com/science/article/pii/S2666379124000405
Jan 2024
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Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus

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  DOI: 10.1016/j.cell.2023.11.031
  
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The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent

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  DOI: 10.1016/j.celrep.2023.113516
  
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Atypical B cells consist of subsets with distinct functional profiles

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  DOI: 10.1016/j.isci.2023.108496
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10720271/
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Proximity extracellular protein-protein interaction analysis of EGFR using AirID-conjugated fragment of antigen binding

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  DOI: 10.1038/s41467-023-43931-7
  
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  DOI: 10.1038/s41467-023-43931-7
  
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nature.com/articles/s41467-023-43931-7
Nov 2023
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A nanobody-based strategy for rapid and scalable purification of human protein complexes

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  DOI: 10.1038/s41596-023-00904-w
  
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link.springer.com/article/10.1038/s41596-023-00904-w
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Membrane remodeling properties of the Parkinson’s disease protein LRRK2

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  DOI: 10.1073/pnas.2309698120
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10614619/
Oct 2023
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An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses

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  DOI: 10.1126/scitranslmed.abn6859
  
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Broadening a SARS-CoV-1–neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution

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  DOI: 10.1126/scisignal.abk3516
  
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Widespread impact of immunoglobulin V-gene allelic polymorphisms on antibody reactivity

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  DOI: 10.1016/j.celrep.2023.113194
  
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Multivalent antigen display on nanoparticle immunogens increases B cell clonotype diversity and neutralization breadth to pneumoviruses

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cell.com/immunity/abstract/S1074-7613(23)00367-9
Sep 2023
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S-531011, a Novel Anti-Human CCR8 Antibody, Induces Potent Antitumor Responses through Depletion of Tumor-Infiltrating CCR8-Expressing Regulatory T Cells

1
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  DOI: 10.1158/1535-7163.MCT-22-0570
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10477828/
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IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function

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Recognition determinants of improved HIV-1 neutralization by a heavy chain matured pediatric antibody

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52.53.155.43/4e2892b16e328023e4cde9b31b0daa48de916ef6/PIIS2589004223016565-html.html
Jul 2023
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Mechanism of orphan subunit recognition during assembly quality control

1
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Scorpionfish BPI is highly active against multiple drug-resistant Pseudomonas aeruginosa isolates from people with cystic fibrosis

1
1. scibot 22 Jul 2023
  
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Novel Frizzled-specific antibody-based Wnt mimetics and Wnt superagonists selectively activate WNT/β-catenin signaling in target tissues

1
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sciencedirect.com/science/article/abs/pii/S2451945623001836
Jun 2023
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Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation

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  DOI: 10.1016/j.molcel.2023.05.020
  
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Vaccine elicitation and structural basis for antibody protection against alphaviruses

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Microglia mediate neurocognitive deficits by eliminating C1q-tagged synapses in sepsis-associated encephalopathy

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  DOI: 10.1126/sciadv.abq7806
  
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science.org/doi/10.1126/sciadv.abq7806
May 2023
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Microglia mediate neurocognitive deficits by eliminating C1q-tagged synapses in sepsis-associated encephalopathy

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  DOI: 10.1126/sciadv.abq7806
  
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Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response

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  DOI: 10.1016/j.str.2023.04.010
  
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Broad immunity to SARS-CoV-2 variants of concern mediated by a SARS-CoV-2 receptor-binding domain protein vaccine

1
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  DOI: 10.1016/j.ebiom.2023.104574
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10159263/
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ESCRT recruitment to SARS-CoV-2 spike induces virus-like particles that improve mRNA vaccines

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  DOI: 10.1016/j.cell.2023.04.024
  
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Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability

1
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Apr 2023
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Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies

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ncbi.nlm.nih.gov/pmc/articles/PMC10115451/
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Selective SARS-CoV2 BA.2 escape of antibody Fc/Fc-receptor interactions

1
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  DOI: 10.1016/j.isci.2023.106582
  
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sciencedirect.com/science/article/pii/S2589004223006594
Mar 2023
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Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines

1
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  DOI: 10.1016/j.celrep.2023.112266
  
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Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope

1
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B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection

1
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  DOI: 10.1016/j.immuni.2023.02.003
  
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Scorpionfish BPI is highly active against multiple drug-resistant Pseudomonas aeruginosa isolates from cystic fibrosis patients

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  DOI: 10.1101/2023.02.19.529133
  
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biorxiv.org/content/10.1101/2023.02.19.529133v1
Feb 2023
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Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs

1
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  DOI: 10.1371/journal.pbio.3001967
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9910744/
Jan 2023
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Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape

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  DOI: 10.1016/j.isci.2022.105726
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9721160/
Dec 2022
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Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants

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  DOI: 10.1016/j.cell.2022.12.018
  
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Assessment of Crosslinkers between Peptide Antigen and Carrier Protein for Fusion Peptide-Directed Vaccines against HIV-1

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  DOI: 10.3390/vaccines10111916
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9698951/
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Cross-reactive SARS-CoV-2 epitope targeted across donors informs immunogen design

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  DOI: 10.1016/j.xcrm.2022.100834
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9663748/
Nov 2022
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Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes

1
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  DOI: 10.1016/j.immuni.2022.10.019
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9606073/
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Multivalent S2-based vaccines provide broad protection against SARS-CoV-2 variants of concern and pangolin coronaviruses

1
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  DOI: 10.1016/j.ebiom.2022.104341
  
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An epitope-enriched immunogen expands responses to a conserved viral site

1
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  DOI: 10.1016/j.celrep.2022.111628
  
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Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses

1
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  DOI: 10.1016/j.chom.2022.10.010
  
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sciencedirect.com/science/article/pii/S1931312822005236
Oct 2022
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Phosphoproteomic mapping reveals distinct signaling actions and activation of muscle protein synthesis by Isthmin-1

1
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ncbi.nlm.nih.gov/pmc/articles/PMC9592085/
Sep 2022
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Antigenic characterization of the SARS-CoV-2 Omicron subvariant BA.2.75

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  DOI: 10.1016/j.chom.2022.09.002
  
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Discovery and intranasal administration of a SARS-CoV-2 broadly acting neutralizing antibody with activity against multiple Omicron subvariants

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TITLE: Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways

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  DOI: 10.1016/j.isci.2022.104914
  
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SARS-CoV-2 specific CD4+ T cell longevity correlates with Th17-like phenotype

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S146L in MYC is a context-dependent activating substitution in cancer development

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Antibodies from primary humoral responses modulate recruitment of naive B cells during secondary responses

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Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein

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Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus

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An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses

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  DOI: 10.1126/scitranslmed.abn6859
  
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Protective prototype-Beta and Delta-Omicron chimeric RBD-dimer vaccines against SARS-CoV-2

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An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses

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Structure of an influenza group 2-neutralizing antibody targeting the hemagglutinin stem supersite

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TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells

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Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity

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A large-scale systematic survey reveals recurring molecular features of public antibody responses to SARS-CoV-2

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Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses

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Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting

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Protocol to identify and monitor key mutations of broadly neutralizing antibody lineages following sequential immunization of Ig-humanized mice

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A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection

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https://biorxiv.org/cgi/content/10.1101/2022.01.25.477770

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Monoclonal antibodies targeting two immunodominant epitopes on the Spike protein neutralize emerging SARS-CoV-2 variants of concern

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Human monoclonal antibodies against Staphylococcus aureus surface antigens recognize in vitro and in vivo biofilm

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Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response

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cancerimmunolres.aacrjournals.org cancerimmunolres.aacrjournals.org

The Fibronectin–ILT3 Interaction Functions as a Stromal Checkpoint that Suppresses Myeloid Cells

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  DOI: 10.1158/2326-6066.CIR-21-0240
  
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A point-of-care lateral flow assay for neutralising antibodies against SARS-CoV-2

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Luminescence complementation technology for the identification of MYC:TRRAP inhibitors

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ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes

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Live Imaging of SARS-CoV-2 Infection in Mice Reveals that Neutralizing Antibodies Require Fc Function for Optimal Efficacy

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Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies

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Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace

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Novel potent anti-STEAP1 bispecific antibody to redirect T cells for cancer immunotherapy

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Modulating tumor infiltrating myeloid cells to enhance bispecific antibody-driven T cell infiltration and anti-tumor response

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Therapeutic alphavirus cross-reactive E1 human antibodies inhibit viral egress

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Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies

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Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization

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  DOI: 10.1016/j.cell.2019.06.030
  
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Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response against Influenza Virus

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Therapeutic Monoclonal Antibodies for Ebola Virus Infection Derived from Vaccinated Humans

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1. scibot 28 Jul 2021
  
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  Human: Expi293F cells
  
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Untitled document

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  DOI: 10.1371/journal.pone.0215163
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6469787/
Jun 2021
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B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV

1
1. scibot 14 Jun 2021
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.cell.2021.04.032
  
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sciencedirect.com/science/article/pii/S0092867421005353
May 2021
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SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2

1
1. scibot 27 May 2021
  
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  DOI: 10.1016/j.immuni.2021.05.006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8106883/
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WNK1 is an assembly factor for the human ER membrane protein complex

1
1. scibot 10 May 2021
  
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  DOI: 10.1016/j.molcel.2021.04.013
  
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Broad and potently neutralizing monoclonal antibodies isolated from human survivors of New World hantavirus infection

1
1. scibot 05 May 2021
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.celrep.2021.109086
  
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sciencedirect.com/science/article/pii/S2211124721004198
Apr 2021
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Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1

1
1. scibot 29 Apr 2021
  
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  DOI: 10.1016/j.chom.2021.02.018
  
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Defining and Manipulating B Cell Immunodominance Hierarchies to Elicit Broadly Neutralizing Antibody Responses against Influenza Virus

1
1. scibot 27 Apr 2021
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.cels.2020.09.005
  
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A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection

1
1. scibot 27 Apr 2021
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.chom.2021.04.005
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8049401/
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Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection

1
1. scibot 24 Apr 2021
  
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  DOI: 10.1016/j.cell.2020.11.011
  
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SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms

1
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  DOI: 10.1016/j.cell.2021.03.027
  
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cell.com/cell/fulltext/S0092-8674(21)00355-X
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The mechanistic basis of protection by non-neutralizing anti-alphavirus antibodies

1
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  DOI: 10.1016/j.celrep.2021.108962
  
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Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class

1
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.celrep.2021.108950
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7972811/
Mar 2021
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SARS-CoV-2 S protein:ACE2 interaction reveals novel allosteric targets

1
1. scibot 10 Mar 2021
  
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  RRID:CVCL_D615
  
  DOI: 10.7554/eLife.63646
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7932696/
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Robust SARS-CoV-2 Infection in Nasal Turbinates after Treatment with Systemic Neutralizing Antibodies

1
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  DOI: 10.1016/j.chom.2021.02.019
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7904446/
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Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth

1
1. scibot 01 Mar 2021
  
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sciencedirect.com/science/article/pii/S1074761320305422
Feb 2021
elifesciences.org elifesciences.org

The structures of secretory and dimeric immunoglobulin A

1
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  RRID:CVCL_D615
  
  DOI: 10.7554/eLife.56098
  
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elifesciences.org/articles/56098
Dec 2020
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Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains

1
1. scibot 10 Dec 2020
  
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  DOI: 10.1016/j.chom.2020.11.004
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7670890/
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Lipocalin-2 is an anorexigenic signal in primates

1
1. scibot 07 Dec 2020
  
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  DOI: 10.7554/eLife.58949
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7685704/
Nov 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles

1
1. scibot 21 Nov 2020
  
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  DOI: 10.1016/j.chom.2020.11.001
  
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pubmed.ncbi.nlm.nih.gov/33242391/
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A Public Health Antibody Screening Indicates a 6-Fold Higher SARS-CoV-2 Exposure Rate than Reported Cases in Children

1
1. scibot 17 Nov 2020
  
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  DOI: 10.1016/j.medj.2020.10.003
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7598360/
Sep 2020
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Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation

1
1. scibot 23 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.108088
  
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sciencedirect.com/science/article/pii/S2211124720310779
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2

1
1. scibot 18 Sep 2020
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.chom.2020.09.002
  
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pubmed.ncbi.nlm.nih.gov/32941787/
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VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage

1
1. scibot 17 Sep 2020
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.chom.2020.01.027
  
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sciencedirect.com/science/article/pii/S1931312820300706
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Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies

1
1. scibot 16 Sep 2020
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.chom.2020.03.025
  
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sciencedirect.com/science/article/pii/S193131282030189X
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Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen

1
1. scibot 16 Sep 2020
  
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  DOI: 10.1038/s41598-020-59711-y
  
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nature.com/articles/s41598-020-59711-y
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Structural and Biophysical Analysis of the CLCA1 VWA Domain Suggests Mode of TMEM16A Engagement

1
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  DOI: 10.1016/j.celrep.2019.12.059
  
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sciencedirect.com/science/article/pii/S2211124719317164
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Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies

1
1. scibot 09 Sep 2020
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7311918/
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VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA

1
1. scibot 06 Sep 2020
  
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  DOI: 10.1016/j.chom.2020.03.024
  
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sciencedirect.com/science/article/pii/S1931312820301888
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A Human IgSF Cell-Surface Interactome Reveals a Complex Network of Protein-Protein Interactions

1
1. scibot 04 Sep 2020
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.cell.2020.07.025
  
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sciencedirect.com/science/article/pii/S0092867420309338
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Non-acylated Wnts Can Promote Signaling

1
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  DOI: 10.1016/j.celrep.2018.12.104
  
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cell.com/cell-reports/fulltext/S2211-1247(18)32079-5
Jan 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Zinc-α2-glycoprotein is an inhibitor of amine oxidase copper-containing 3

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_D615
  
  DOI: 10.1098/rsob.190035
  
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pubmed.ncbi.nlm.nih.gov/32315567/
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Pathogenic Autoreactive T and B Cells Cross-React with Mimotopes Expressed by a Common Human Gut Commensal to Trigger Autoimmunity

1
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.chom.2019.05.003
  
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sciencedirect.com/science/article/pii/S1931312819302483
journals.plos.org journals.plos.org

Untitled document

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1371/journal.pone.0215163
  
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journals.plos.org/plosone/article
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Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection

1
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.cell.2019.04.036
  
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sciencedirect.com/science/article/pii/S0092867419304556
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Untitled document

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1. scibot 12 Jan 2020
  
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  DOI: 10.1016/j.celrep.2018.12.104
  
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sciencedirect.com/science/article/pii/S2211124718320795
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Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition

1
1. scibot 12 Jan 2020
  
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  RRID:CVCL_D615
  
  DOI: 10.1016/j.str.2018.10.007
  
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sciencedirect.com/science/article/pii/S096921261830368X
Nov 2018
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Synthetic DNA delivery by electroporation promotes robust in vivo sulfation of broadly neutralizing anti-HIV immunoadhesin eCD4-Ig

1
1. scibot 05 Nov 2018
  
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  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S2352396418303128
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A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope

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1. scibot 05 Nov 2018
  
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  RRID:CVCL_D615
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1074761318300712
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Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0092867417314319
Nov 2017
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Untitled document

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1. scibot 08 Nov 2017
  
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  Curator: @patriciaelyse_
  
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eneuro.org/content/4/4/ENEURO.0100-17.2017
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Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop

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1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S1074761317301760
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Multidimensional Tracking of GPCR Signaling via Peroxidase-Catalyzed Proximity Labeling

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1. scibot 08 Nov 2017
  
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  Expi293F Cells
  
  Curator: @gabimpine
  
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sciencedirect.com/science/article/pii/S0092867417303471

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