110 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Large adipocytes alter mode of lipid release and promote breast cancer malignancy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11996363/
  3. Sep 2025
  4. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    TSH Ligand-Based CAR-T Cell Effectively Eradicates TSHR-Positive Thyroid Cancer with Favorable Safety Profile
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202513243
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    Liver-breast communication of adipocyte-oriented exosomes drives primary mammary cancer progression
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    sciencedirect.com/science/article/pii/S1550413125003857
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    Drug screening in 3D microtumors reveals DDR1/2-MAPK12-GLI1 as a vulnerability in cancer-associated fibroblasts
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    sciencedirect.com/science/article/pii/S2666379125004306
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    Modulation of fibronectin extracellular matrix enhances anti-tumor efficacy of immune checkpoint blockade
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    sciencedirect.com/science/article/pii/S2666379125003957
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Peach Gum Polysaccharide Prevents Chemotherapy-Induced Intestinal Injury and Degenerative Behavior
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    pmc.ncbi.nlm.nih.gov/articles/PMC12375157/
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    Tumors hijack macrophages for iron supply to promote bone metastasis and anemia
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    sciencedirect.com/science/article/pii/S0092867425009274
  10. Aug 2025
  11. journals.sagepub.com journals.sagepub.com
    Peach Gum Polysaccharide Prevents Chemotherapy-Induced Intestinal Injury and Degenerative Behavior
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    journals.sagepub.com/doi/full/10.1177/15347354251368410
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    Fc-optimized CD40 agonistic antibody elicits tertiary lymphoid structure formation and systemic antitumor immunity in metastatic cancer
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    sciencedirect.com/science/article/pii/S1535610825003198
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    T cells Instruct Immune Checkpoint Inhibitor Therapy Resistance in Tumors Responsive to IL-1 and TNFα Inflammation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11790381/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12317733/
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    Aging-induced semaphorin 7a promotes TGF-β1-mediated cell plasticity and breast tumor metastases
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    sciencedirect.com/science/article/pii/S2211124725008137
  16. Jul 2025
  17. www.nature.com www.nature.com
    Secretogranin 2 binds LILRB4 resulting in immunosuppression
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    nature.com/articles/s41590-025-02233-4
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MARCO expression on myeloid-derived suppressor cells is essential for their differentiation and immunosuppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12283920/
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    A fluorescent STING ligand sensor for high-throughput screening of compounds that can enhance tumor immunotherapy
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    sciencedirect.com/science/article/pii/S2667237525001420
  20. dx.doi.org dx.doi.org
    Genetic and pharmacological targeting of nicotinic acetylcholine receptor action blocks tumor progression in mouse models of breast cancer
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    dx.doi.org/10.1093/jimmun/vkaf148
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214879/
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    The immune response against cancer is modulated by stromal cell fibronectin
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    sciencedirect.com/science/article/pii/S1476558625000764
  23. Jun 2025
  24. 52.53.155.43 52.53.155.43
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  25. May 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EYA3 regulation of NF-κB and CCL2 suppresses cytotoxic NK cells in the premetastatic niche to promote TNBC metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12057687/
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    Semaphorin7A and PD-L1 cooperatively drive immunosuppression during mammary involution and breast cancer
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    sciencedirect.com/science/article/pii/S2211124725004474
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    Sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity
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    sciencedirect.com/science/article/pii/S1074761325001839
  29. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of autotaxin activity with IOA-289 decreases fibrosis in mouse E0771 breast tumors
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35471
  30. Apr 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    cGAS and STING in Host Myeloid Cells Are Essential for Effective Cyclophosphamide Treatment of Advanced Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11987962/
  32. 52.53.155.43 52.53.155.43
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    Cancer cell-derived arginine fuels polyamine biosynthesis in tumor-associated macrophages to promote immune evasion
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    sciencedirect.com/science/article/pii/S1535610825001163
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fluorescence Lifetime Imaging Enables In Vivo Quantification of PD-L1 Expression and Intertumoral Heterogeneity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11967911/
  35. 52.53.155.43 52.53.155.43
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  36. Mar 2025
  37. www.biorxiv.org www.biorxiv.org
    TEAD inhibition alters the lung immune microenvironment and attenuates metastasis
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    biorxiv.org/content/10.1101/2025.02.26.639326v1
  38. aacrjournals.org aacrjournals.org
    Blocking WNT7A Enhances MHC-I Antigen Presentation and Enhances the Effectiveness of Immune Checkpoint Blockade Therapy
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    aacrjournals.org/cancerimmunolres/article/13/3/400/752015/Blocking-WNT7A-Enhances-MHC-I-Antigen-Presentation
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    DA-DRD5 signaling reprograms B cells to promote CD8+ T cell-mediated antitumor immunity
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    sciencedirect.com/science/article/pii/S2211124725001354
  40. Feb 2025
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics
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    pmc.ncbi.nlm.nih.gov/articles/PMC11842356/
  42. 52.53.155.43 52.53.155.43
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  43. aacrjournals.org aacrjournals.org
    Triple-negative breast cancer-derived extracellular vesicles promote a hepatic pre-metastatic niche via a cascade of microenvironment remodeling
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    aacrjournals.org/mcr/article/21/7/726/727474/Triple-Negative-Breast-Cancer-Derived
  44. aacrjournals.org aacrjournals.org
    Single-cell Transcriptomic Analysis Identifies Senescent Osteocytes that Trigger Bone Destruction in Breast Cancer Metastasis
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    aacrjournals.org/cancerres/article/84/23/3936/750181/Single-Cell-Transcriptomic-Analysis-Identifies
  45. Jan 2025
  46. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17437
  47. 52.53.155.43 52.53.155.43
    The bacterial microbiome modulates the initiation of brain metastasis by impacting the gut-to-brain axis
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  48. Dec 2024
  49. www.sciencedirect.com www.sciencedirect.com
    Antigen presentation by tumor-associated macrophages drives T cells from a progenitor exhaustion state to terminal exhaustion
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    sciencedirect.com/science/article/pii/S1074761324005417
  50. www.sciencedirect.com www.sciencedirect.com
    Arming Oncolytic M1 Virus with Gasdermin E Enhances Antitumor Efficacy in Breast Cancer
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    sciencedirect.com/science/article/pii/S2589004224023733
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    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
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    sciencedirect.com/science/article/pii/S0092867424013266
  52. Nov 2024
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11555046/
  54. 52.53.155.43 52.53.155.43
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  55. Sep 2024
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11401886/
  57. Jul 2024
  58. www.sciencedirect.com www.sciencedirect.com
    Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors
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    sciencedirect.com/science/article/pii/S0092867424006536
  59. May 2024
  60. www.sciencedirect.com www.sciencedirect.com
    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
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    sciencedirect.com/science/article/pii/S1535610824001697
  61. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Preclinical and translational pharmacology of afucosylated anti-CCR8 antibody for depletion of tumour-infiltrating regulatory T cells
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16326
  62. www.sciencedirect.com www.sciencedirect.com
    Identification of the extracellular membrane protein ENPP3 as a major cGAMP hydrolase and innate immune checkpoint
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    sciencedirect.com/science/article/pii/S2211124724005370
  63. www.sciencedirect.com www.sciencedirect.com
    Inhibition of protein translational machinery in triple-negative breast cancer as a promising therapeutic strategy
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    sciencedirect.com/science/article/pii/S2666379124002441
  64. www.biorxiv.org www.biorxiv.org
    Direct excitatory synapses between neurons and tumor cells drive brain metastatic seeding of breast cancer and melanoma
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    biorxiv.org/content/10.1101/2024.01.08.574608v1
  65. Apr 2024
  66. aacrjournals.org aacrjournals.org
    Spatial and temporal mapping of breast cancer lung metastases identify TREM2 macrophages as regulators of the metastatic boundary
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    aacrjournals.org/cancerdiscovery/article/13/12/2610/731625/Spatial-and-Temporal-Mapping-of-Breast-Cancer-Lung
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10980159/
  68. Mar 2024
  69. www.sciencedirect.com www.sciencedirect.com
    Targeting tumor-intrinsic SLC16A3 to enhance anti-PD-1 efficacy via tumor immune microenvironment reprogramming
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    sciencedirect.com/science/article/pii/S0304383524002179
  70. www.sciencedirect.com www.sciencedirect.com
    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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    sciencedirect.com/science/article/pii/S221112472400264X
  71. Feb 2024
  72. www.sciencedirect.com www.sciencedirect.com
    Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
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    sciencedirect.com/science/article/pii/S1550413124000068
  73. Jan 2024
  74. aacrjournals.org aacrjournals.org
    Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade
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    aacrjournals.org/cancerdiscovery/article/13/12/2566/731588/Formate-Supplementation-Enhances-Antitumor-CD8-T
  75. Dec 2023
  76. www.sciencedirect.com www.sciencedirect.com
    Choroid plexus mast cells drive tumor-associated hydrocephalus
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    sciencedirect.com/science/article/pii/S0092867423011820
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  79. Nov 2023
  80. www.sciencedirect.com www.sciencedirect.com
    Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2589004223023854
  81. www.embopress.org www.embopress.org
    Breast adipose tissue-derived extracellular vesicles from obese women alter tumor cell metabolism
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    embopress.org/doi/full/10.15252/embr.202357339
  82. www.nature.com www.nature.com
    Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis
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    nature.com/articles/s41556-023-01273-y
  83. Jul 2023
  84. 52.53.155.43 52.53.155.43
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  85. Jun 2023
  86. aacrjournals.org aacrjournals.org
    Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization
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    aacrjournals.org/cancerres/article/83/8/1299/725102/Active-Remodeling-of-Capillary-Endothelium-via
  87. May 2023
  88. www.sciencedirect.com www.sciencedirect.com
    ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis
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    sciencedirect.com/science/article/pii/S2211124723005739
  89. academic.oup.com academic.oup.com
    Short-term topiramate treatment prevents radiation-induced cytotoxic edema in preclinical models of breast-cancer brain metastasis
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    academic.oup.com/neuro-oncology/advance-article/doi/10.1093/neuonc/noad070/7117706
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983870/
  91. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The role of microglia in 67NR mammary tumor-induced suppression of brain responses to immune challenges in female mice
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.15830
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    18F-FMISO PET Imaging Identifies Hypoxia and Immunosuppressive Tumor Microenvironments and Guides Targeted Evofosfamide Therapy in Tumors Refractory to PD-1 and CTLA-4 Inhibition
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    ncbi.nlm.nih.gov/pmc/articles/PMC8776604/
  93. Apr 2023
  94. www.biorxiv.org www.biorxiv.org
    Steroid Receptor Coactivator-3 is a Key Modulator of Regulatory T Cell-Mediated Tumor Evasion
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    biorxiv.org/content/10.1101/2023.03.28.534575v1
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combining an Alarmin HMGN1 Peptide with PD-L1 Blockade Results in Robust Antitumor Effects with a Concomitant Increase of Stem-Like/Progenitor Exhausted CD8+ T Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10087296/
  96. Mar 2023
  97. www.biorxiv.org www.biorxiv.org
    Short-term Topiramate treatment prevents radiation-induced cytotoxic edema in preclinical models of breast-cancer brain metastasis
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    biorxiv.org/content/10.1101/2023.02.14.528559v1
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Actionable Targets for Breast Cancer Intervention Using a Diversity Outbred Mouse Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC10034465/
  99. Feb 2023
  100. aacrjournals.org aacrjournals.org
    Bone metastasis initiation is coupled with bone remodeling through osteogenic differentiation of NG2+ cells
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    aacrjournals.org/cancerdiscovery/article/13/2/474/716294/Bone-Metastasis-Initiation-Is-Coupled-with-Bone
  101. Jan 2023
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9821869/
  103. www.science.org www.science.org
    ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis
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    science.org/doi/10.1126/sciadv.abq3951
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index
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    ncbi.nlm.nih.gov/pmc/articles/PMC9377749/
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Immunogenic MHC Class II Human HER3 Peptides that Mediate Anti-HER3 CD4+ Th1 Responses and Potential Use as a Cancer Vaccine
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    ncbi.nlm.nih.gov/pmc/articles/PMC9414303/
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9262841/
  107. Dec 2022
  108. 52.53.155.43 52.53.155.43
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  109. Nov 2022
  110. www.nature.com www.nature.com
    Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation
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    nature.com/articles/s41467-022-34346-x
  111. www.sciencedirect.com www.sciencedirect.com
    CD16+ fibroblasts foster a trastuzumab-refractory microenvironment that is reversed by VAV2 inhibition
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    sciencedirect.com/science/article/pii/S1535610822005062
  112. Sep 2022
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity
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  114. Jun 2022
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  117. Apr 2022
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  119. Mar 2022
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  121. Dec 2021
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  123. Nov 2021
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  126. Sep 2021
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  128. Aug 2021
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  130. Jun 2021
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  132. May 2021
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    Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth
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  135. Apr 2021
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    Structure-Aided Development of Small-Molecule Inhibitors of ENPP1, the Extracellular Phosphodiesterase of the Immunotransmitter cGAMP
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  138. Feb 2021
  139. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  140. Jan 2021
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  143. Dec 2020
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  145. Nov 2020
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  147. Sep 2020
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  152. Jan 2020
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    Contrasting Effects of IGF Binding Protein-3 Expression in Mammary Tumor Cells and the Tumor Microenvironment
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  154. Nov 2017
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