104 Matching Annotations
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    Tumors hijack macrophages for iron supply to promote bone metastasis and anemia
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  3. Aug 2025
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    Peach Gum Polysaccharide Prevents Chemotherapy-Induced Intestinal Injury and Degenerative Behavior
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    Fc-optimized CD40 agonistic antibody elicits tertiary lymphoid structure formation and systemic antitumor immunity in metastatic cancer
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    T cells Instruct Immune Checkpoint Inhibitor Therapy Resistance in Tumors Responsive to IL-1 and TNFα Inflammation
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    A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression
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    Aging-induced semaphorin 7a promotes TGF-β1-mediated cell plasticity and breast tumor metastases
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  9. Jul 2025
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    Secretogranin 2 binds LILRB4 resulting in immunosuppression
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    MARCO expression on myeloid-derived suppressor cells is essential for their differentiation and immunosuppression
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    A fluorescent STING ligand sensor for high-throughput screening of compounds that can enhance tumor immunotherapy
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    Genetic and pharmacological targeting of nicotinic acetylcholine receptor action blocks tumor progression in mouse models of breast cancer
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    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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    The immune response against cancer is modulated by stromal cell fibronectin
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  16. Jun 2025
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  18. May 2025
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    EYA3 regulation of NF-κB and CCL2 suppresses cytotoxic NK cells in the premetastatic niche to promote TNBC metastasis
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    Semaphorin7A and PD-L1 cooperatively drive immunosuppression during mammary involution and breast cancer
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    Sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity
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    Inhibition of autotaxin activity with IOA-289 decreases fibrosis in mouse E0771 breast tumors
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  23. Apr 2025
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    cGAS and STING in Host Myeloid Cells Are Essential for Effective Cyclophosphamide Treatment of Advanced Breast Cancer
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    Cancer cell-derived arginine fuels polyamine biosynthesis in tumor-associated macrophages to promote immune evasion
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    Fluorescence Lifetime Imaging Enables In Vivo Quantification of PD-L1 Expression and Intertumoral Heterogeneity
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  29. Mar 2025
  30. www.biorxiv.org www.biorxiv.org
    TEAD inhibition alters the lung immune microenvironment and attenuates metastasis
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    Blocking WNT7A Enhances MHC-I Antigen Presentation and Enhances the Effectiveness of Immune Checkpoint Blockade Therapy
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    DA-DRD5 signaling reprograms B cells to promote CD8+ T cell-mediated antitumor immunity
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  33. Feb 2025
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    Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics
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    Single-cell Transcriptomic Analysis Identifies Senescent Osteocytes that Trigger Bone Destruction in Breast Cancer Metastasis
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  38. Jan 2025
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    The bacterial microbiome modulates the initiation of brain metastasis by impacting the gut-to-brain axis
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    Antigen presentation by tumor-associated macrophages drives T cells from a progenitor exhaustion state to terminal exhaustion
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    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
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  45. Nov 2024
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    Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis
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  48. Sep 2024
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  50. Jul 2024
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    Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors
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  52. May 2024
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    Identification of the extracellular membrane protein ENPP3 as a major cGAMP hydrolase and innate immune checkpoint
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    Direct excitatory synapses between neurons and tumor cells drive brain metastatic seeding of breast cancer and melanoma
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  58. Apr 2024
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    Spatial and temporal mapping of breast cancer lung metastases identify TREM2 macrophages as regulators of the metastatic boundary
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    Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
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  61. Mar 2024
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    Targeting tumor-intrinsic SLC16A3 to enhance anti-PD-1 efficacy via tumor immune microenvironment reprogramming
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  64. Feb 2024
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    Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
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  66. Jan 2024
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  68. Dec 2023
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    Choroid plexus mast cells drive tumor-associated hydrocephalus
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  72. Nov 2023
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    Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer
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  76. Jul 2023
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  78. Jun 2023
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  80. May 2023
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    ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis
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    Short-term topiramate treatment prevents radiation-induced cytotoxic edema in preclinical models of breast-cancer brain metastasis
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    Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation
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    The role of microglia in 67NR mammary tumor-induced suppression of brain responses to immune challenges in female mice
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    18F-FMISO PET Imaging Identifies Hypoxia and Immunosuppressive Tumor Microenvironments and Guides Targeted Evofosfamide Therapy in Tumors Refractory to PD-1 and CTLA-4 Inhibition
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  86. Apr 2023
  87. www.biorxiv.org www.biorxiv.org
    Steroid Receptor Coactivator-3 is a Key Modulator of Regulatory T Cell-Mediated Tumor Evasion
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    biorxiv.org/content/10.1101/2023.03.28.534575v1
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    Combining an Alarmin HMGN1 Peptide with PD-L1 Blockade Results in Robust Antitumor Effects with a Concomitant Increase of Stem-Like/Progenitor Exhausted CD8+ T Cells
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  89. Mar 2023
  90. www.biorxiv.org www.biorxiv.org
    Short-term Topiramate treatment prevents radiation-induced cytotoxic edema in preclinical models of breast-cancer brain metastasis
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    biorxiv.org/content/10.1101/2023.02.14.528559v1
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Actionable Targets for Breast Cancer Intervention Using a Diversity Outbred Mouse Model
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  92. Feb 2023
  93. aacrjournals.org aacrjournals.org
    Bone metastasis initiation is coupled with bone remodeling through osteogenic differentiation of NG2+ cells
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  94. Jan 2023
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis
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  96. www.science.org www.science.org
    ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis
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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index
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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Immunogenic MHC Class II Human HER3 Peptides that Mediate Anti-HER3 CD4+ Th1 Responses and Potential Use as a Cancer Vaccine
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    ncbi.nlm.nih.gov/pmc/articles/PMC9414303/
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9262841/
  100. Dec 2022
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  102. Nov 2022
  103. www.nature.com www.nature.com
    Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation
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    nature.com/articles/s41467-022-34346-x
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    CD16+ fibroblasts foster a trastuzumab-refractory microenvironment that is reversed by VAV2 inhibition
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  105. Sep 2022
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity
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    ncbi.nlm.nih.gov/pmc/articles/PMC8904293/
  107. Jun 2022
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    A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
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  110. Apr 2022
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    Meflin-positive cancer-associated fibroblasts enhance tumor response to immune checkpoint blockade
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  112. Mar 2022
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    Tumor-derived Jagged1 promotes cancer progression through immune evasion
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  114. Dec 2021
  115. mcr.aacrjournals.org mcr.aacrjournals.org
    Opposing Effects of Granulocyte Colony-Stimulating Factor on the Initiation and Progression of Breast Cancer Bone Metastases
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  116. Nov 2021
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    The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1
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  119. Sep 2021
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  121. Aug 2021
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  123. Jun 2021
  124. www.nature.com www.nature.com
    Oxytocin receptor induces mammary tumorigenesis through prolactin/p-STAT5 pathway
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  125. May 2021
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    Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
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    Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth
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  128. Apr 2021
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    Structure-Aided Development of Small-Molecule Inhibitors of ENPP1, the Extracellular Phosphodiesterase of the Immunotransmitter cGAMP
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  130. www.cell.com www.cell.com
    Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity
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  131. Feb 2021
  132. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Targeting stromal cell Syndecan‐2 reduces breast tumour growth, metastasis and limits immune evasion
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  133. Jan 2021
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    Time-restricted feeding normalizes hyperinsulinemia to inhibit breast cancer in obese postmenopausal mouse models
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanical Loading-Driven Tumor Suppression Is Mediated by Lrp5-Dependent and Independent Mechanisms
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  136. Dec 2020
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    Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells
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  138. Nov 2020
  139. www.frontiersin.org www.frontiersin.org
    Obesity-Associated Myeloid-Derived Suppressor Cells Promote Apoptosis of Tumor-Infiltrating CD8 T Cells and Immunotherapy Resistance in Breast Cancer
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  140. Sep 2020
  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WNT1-inducible signaling pathway protein 1 (WISP1/CCN4) stimulates melanoma invasion and metastasis by promoting the epithelial–mesenchymal transition
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  145. Jan 2020
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    Contrasting Effects of IGF Binding Protein-3 Expression in Mammary Tumor Cells and the Tumor Microenvironment
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  147. Nov 2017
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