60 Matching Annotations
  1. Apr 2024
  2. aacrjournals.org aacrjournals.org
    Spatial and temporal mapping of breast cancer lung metastases identify TREM2 macrophages as regulators of the metastatic boundary
    1
    1. scibot 19 Apr 2024
      RRID:CVCL_GR23

      DOI: 10.1158/2159-8290.CD-23-0299

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    aacrjournals.org/cancerdiscovery/article/13/12/2610/731625/Spatial-and-Temporal-Mapping-of-Breast-Cancer-Lung
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
    1
    1. scibot 11 Apr 2024
      RRID:CVCL_GR23

      DOI: 10.21203/rs.3.rs-4047486/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10980159/
  4. Mar 2024
  5. www.sciencedirect.com www.sciencedirect.com
    Targeting tumor-intrinsic SLC16A3 to enhance anti-PD-1 efficacy via tumor immune microenvironment reprogramming
    1
    1. scibot 27 Mar 2024
      RRID:CVCL_GR23

      DOI: 10.1016/j.canlet.2024.216824

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    sciencedirect.com/science/article/pii/S0304383524002179
  6. www.sciencedirect.com www.sciencedirect.com
    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
    1
    1. scibot 19 Mar 2024
      ATCCCat# CRL-3461

      DOI: 10.1016/j.celrep.2024.113936

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      Curator: @abever99

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    sciencedirect.com/science/article/pii/S221112472400264X
  7. Feb 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
    1
    1. scibot 06 Feb 2024
      ATCCCRL-3461

      DOI: 10.1016/j.cmet.2024.01.005

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    sciencedirect.com/science/article/pii/S1550413124000068
  9. Jan 2024
  10. dx.doi.org dx.doi.org
    Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade
    1
    1. scibot 11 Jan 2024
      RRID:CVCL_GR23

      DOI: 10.1158/2159-8290.CD-22-1301

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    dx.doi.org/10.1158/2159-8290.CD-22-1301
  11. Dec 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Choroid plexus mast cells drive tumor-associated hydrocephalus
    1
    1. scibot 20 Dec 2023
      RRID:CVCL_GR23

      DOI: 10.1016/j.cell.2023.11.001

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    sciencedirect.com/science/article/pii/S0092867423011820
  13. 52.53.155.43 52.53.155.43
    cd-23-0299-html.html
    1
    1. scibot 01 Dec 2023
      RRID:CVCL_GR23

      DOI: 10.1158/2159-8290.cd-23-0299

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    52.53.155.43/2b6c279d82b7a0e0d491057f5790a1189e93077e/cd-23-0299-html.html
  14. 52.53.155.43 52.53.155.43
    cd-22-1301-html.html
    1
    1. scibot 01 Dec 2023
      RRID:CVCL_GR23

      DOI: 10.1158/2159-8290.cd-22-1301

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    52.53.155.43/ed2c7eab61775ee4a9efbdfa91d6b4b18a13354a/cd-22-1301-html.html
  15. Nov 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer
    1
    1. scibot 18 Nov 2023
      CVCL_GR23

      DOI: 10.1016/j.isci.2023.108308

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    sciencedirect.com/science/article/pii/S2589004223023854
  17. www.embopress.org www.embopress.org
    Breast adipose tissue-derived extracellular vesicles from obese women alter tumor cell metabolism
    1
    1. scibot 17 Nov 2023
      RRID:CVCL_GR23

      DOI: 10.15252/embr.202357339

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    embopress.org/doi/full/10.15252/embr.202357339
  18. www.nature.com www.nature.com
    Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis
    1
    1. scibot 15 Nov 2023
      RRID:CVCL_GR23

      DOI: 10.1038/s41556-023-01273-y

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    nature.com/articles/s41556-023-01273-y
  19. Jul 2023
  20. 52.53.155.43 52.53.155.43
    mcr-22-0673-html.html
    1
    1. scibot 02 Jul 2023
      CVCL_GR23

      DOI: 10.1158/1541-7786.mcr-22-0673

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    52.53.155.43/5cc780ea6bc578a6755d505f34922fb0e77b2333/mcr-22-0673-html.html
  21. Jun 2023
  22. aacrjournals.org aacrjournals.org
    Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization
    1
    1. scibot 03 Jun 2023
      RRID:CVCL_GR23

      DOI: 10.1158/0008-5472.CAN-22-3964

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    aacrjournals.org/cancerres/article/83/8/1299/725102/Active-Remodeling-of-Capillary-Endothelium-via
  23. May 2023
  24. www.sciencedirect.com www.sciencedirect.com
    ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis
    1
    1. scibot 31 May 2023
      RRID:CVCL_GR23

      DOI: 10.1016/j.celrep.2023.112562

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    sciencedirect.com/science/article/pii/S2211124723005739
  25. academic.oup.com academic.oup.com
    Short-term topiramate treatment prevents radiation-induced cytotoxic edema in preclinical models of breast-cancer brain metastasis
    1
    1. scibot 20 May 2023
      RRID:CVCL_GR23

      DOI: 10.1093/neuonc/noad070

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    academic.oup.com/neuro-oncology/advance-article/doi/10.1093/neuonc/noad070/7117706
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation
    1
    1. scibot 18 May 2023
      RRID:CVCL_GR23

      DOI: 10.1101/2023.05.10.540211

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      Curator: @jmitrevska

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983870/
  27. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The role of microglia in 67NR mammary tumor-induced suppression of brain responses to immune challenges in female mice
    1
    1. scibot 12 May 2023
      RRID:CVCL_GR23

      DOI: 10.1111/jnc.15830

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.15830
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    18F-FMISO PET Imaging Identifies Hypoxia and Immunosuppressive Tumor Microenvironments and Guides Targeted Evofosfamide Therapy in Tumors Refractory to PD-1 and CTLA-4 Inhibition
    1
    1. scibot 05 May 2023
      RRID:CVCL_GR23

      DOI: 10.1158/1078-0432.CCR-21-2394

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    ncbi.nlm.nih.gov/pmc/articles/PMC8776604/
  29. Apr 2023
  30. www.biorxiv.org www.biorxiv.org
    Steroid Receptor Coactivator-3 is a Key Modulator of Regulatory T Cell-Mediated Tumor Evasion
    1
    1. scibot 20 Apr 2023
      RRID:CVCL_GR23

      DOI: 10.1101/2023.03.28.534575

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    biorxiv.org/content/10.1101/2023.03.28.534575v1
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combining an Alarmin HMGN1 Peptide with PD-L1 Blockade Results in Robust Antitumor Effects with a Concomitant Increase of Stem-Like/Progenitor Exhausted CD8+ T Cells
    1
    1. scibot 14 Apr 2023
      CVCL_GR23

      DOI: 10.1158/2326-6066.CIR-21-0265

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    ncbi.nlm.nih.gov/pmc/articles/PMC10087296/
  32. Mar 2023
  33. www.biorxiv.org www.biorxiv.org
    Short-term Topiramate treatment prevents radiation-induced cytotoxic edema in preclinical models of breast-cancer brain metastasis
    1
    1. scibot 31 Mar 2023
      RRID:CVCL_GR23

      DOI: 10.1101/2023.02.14.528559

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    biorxiv.org/content/10.1101/2023.02.14.528559v1
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Actionable Targets for Breast Cancer Intervention Using a Diversity Outbred Mouse Model
    1
    1. scibot 26 Mar 2023
      RRID:CVCL_GR23

      DOI: 10.1016/j.isci.2023.106320

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    ncbi.nlm.nih.gov/pmc/articles/PMC10034465/
  35. Feb 2023
  36. aacrjournals.org aacrjournals.org
    Bone metastasis initiation is coupled with bone remodeling through osteogenic differentiation of NG2+ cells
    1
    1. scibot 18 Feb 2023
      RRID:CVCL_GR23

      DOI: 10.1158/2159-8290.CD-22-0220

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    aacrjournals.org/cancerdiscovery/article/13/2/474/716294/Bone-Metastasis-Initiation-Is-Coupled-with-Bone
  37. Jan 2023
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis
    1
    1. scibot 20 Jan 2023
      RRID:CVCL_GR23

      DOI: 10.1126/sciadv.abq3951

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    ncbi.nlm.nih.gov/pmc/articles/PMC9821869/
  39. www.science.org www.science.org
    ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis
    1
    1. scibot 12 Jan 2023
      RRID:CVCL_GR23

      DOI: 10.1126/sciadv.abq3951

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    science.org/doi/10.1126/sciadv.abq3951
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index
    1
    1. scibot 12 Jan 2023
      CVCL_GR23

      DOI: 10.1158/1535-7163.MCT-21-0518

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    ncbi.nlm.nih.gov/pmc/articles/PMC9377749/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Immunogenic MHC Class II Human HER3 Peptides that Mediate Anti-HER3 CD4+ Th1 Responses and Potential Use as a Cancer Vaccine
    1
    1. scibot 11 Jan 2023
      CVCL_GR23

      DOI: 10.1158/2326-6066.CIR-21-0454

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    ncbi.nlm.nih.gov/pmc/articles/PMC9414303/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1
    1
    1. scibot 07 Jan 2023
      CVCL_GR23

      DOI: 10.1158/2159-8290.CD-21-0900

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    ncbi.nlm.nih.gov/pmc/articles/PMC9262841/
  43. Dec 2022
  44. 52.53.155.43 52.53.155.43
    cd-22-0220-html.html
    1
    1. scibot 03 Dec 2022
      CVCL_GR23

      DOI: 10.1158/2159-8290.cd-22-0220

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    52.53.155.43/b725a3c3e409b5ecfb6e439733821b69db1577f5/cd-22-0220-html.html
  45. Nov 2022
  46. www.nature.com www.nature.com
    Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation
    1
    1. scibot 17 Nov 2022
      RRID:CVCL_GR23

      DOI: 10.1038/s41467-022-34346-x

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    nature.com/articles/s41467-022-34346-x
  47. www.sciencedirect.com www.sciencedirect.com
    CD16+ fibroblasts foster a trastuzumab-refractory microenvironment that is reversed by VAV2 inhibition
    1
    1. scibot 16 Nov 2022
      RRID:CVCL_GR23

      DOI: 10.1016/j.ccell.2022.10.015

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    sciencedirect.com/science/article/pii/S1535610822005062
  48. Sep 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity
    1
    1. scibot 02 Sep 2022
      RRID:CVCL_GR23

      DOI: 10.1158/2159-8290.CD-21-0694

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    ncbi.nlm.nih.gov/pmc/articles/PMC8904293/
  50. Jun 2022
  51. 52.53.155.43 52.53.155.43
    cd-21-0900-html.html
    3
    1. scibot 30 Jun 2022
      RRID:CVCL_GR23

      DOI: 10.1158/2159-8290.cd-21-0900

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    2. scibot 25 Jun 2022
      RRID:CVCL_GR23

      DOI: 10.1158/2159-8290.cd-21-0900

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    3. scibot 22 Jun 2022
      RRID:CVCL_GR23

      DOI: 10.1158/2159-8290.cd-21-0900

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    52.53.155.43/d5bf83c5c1736aa8a79b5cf8b82689398b415edf/cd-21-0900 (2)-html.html
  52. www.sciencedirect.com www.sciencedirect.com
    A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
    1
    1. scibot 02 Jun 2022
      RRID:CVCL_GR23

      DOI: 10.1016/j.molcel.2022.05.008

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    sciencedirect.com/science/article/pii/S1097276522004427
  53. Apr 2022
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Meflin-positive cancer-associated fibroblasts enhance tumor response to immune checkpoint blockade
    1
    1. scibot 08 Apr 2022
      RRID:CVCL_GR23

      DOI: 10.26508/lsa.202101230

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    ncbi.nlm.nih.gov/pmc/articles/PMC8897596/
  55. Mar 2022
  56. www.sciencedirect.com www.sciencedirect.com
    Tumor-derived Jagged1 promotes cancer progression through immune evasion
    1
    1. scibot 09 Mar 2022
      RRID:CVCL_GR23

      DOI: 10.1016/j.celrep.2022.110492

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    sciencedirect.com/science/article/pii/S221112472200225X
  57. Dec 2021
  58. mcr.aacrjournals.org mcr.aacrjournals.org
    Opposing Effects of Granulocyte Colony-Stimulating Factor on the Initiation and Progression of Breast Cancer Bone Metastases
    1
    1. scibot 22 Dec 2021
      RRID:CVCL_GR23

      DOI: 10.1158/1541-7786.MCR-21-0243

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    mcr.aacrjournals.org/content/19/12/2110
  59. Nov 2021
  60. www.sciencedirect.com www.sciencedirect.com
    The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1
    1
    1. scibot 25 Nov 2021
      CVCL_GR23

      DOI: 10.1016/j.ccell.2021.11.002

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    sciencedirect.com/science/article/pii/S1535610821006024
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Interleukin-30 feeds breast cancer stem cells via CXCL10 and IL23 autocrine loops and shapes immune contexture and host outcome
    1
    1. scibot 05 Nov 2021
      RRID:CVCL_GR23

      DOI: 10.1136/jitc-2021-002966

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    ncbi.nlm.nih.gov/pmc/articles/PMC8524378/
  62. Sep 2021
  63. www.sciencedirect.com www.sciencedirect.com
    Effects of exercise and anti-PD-1 on the tumour microenvironment
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    1. scibot 08 Sep 2021
      RRID:CVCL_GR23

      DOI: 10.1016/j.imlet.2021.08.005

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    sciencedirect.com/science/article/abs/pii/S0165247821001401
  64. Aug 2021
  65. www.sciencedirect.com www.sciencedirect.com
    Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles
    1
    1. scibot 01 Aug 2021
      RRID:CVCL_GR23

      DOI: 10.1016/j.celrep.2019.05.008

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    sciencedirect.com/science/article/pii/S2211124719306199
  66. Jun 2021
  67. www.nature.com www.nature.com
    Oxytocin receptor induces mammary tumorigenesis through prolactin/p-STAT5 pathway
    1
    1. scibot 11 Jun 2021
      RRID:CVCL_GR23

      DOI: 10.1038/s41419-021-03849-8

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    nature.com/articles/s41419-021-03849-8
  68. May 2021
  69. www.sciencedirect.com www.sciencedirect.com
    Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
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    1. scibot 10 May 2021
      RRID:CVCL_GR23

      DOI: 10.1016/j.cell.2021.04.016

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    sciencedirect.com/science/article/pii/S0092867421004955
  70. www.sciencedirect.com www.sciencedirect.com
    Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth
    1
    1. scibot 01 May 2021
      RRID:CVCL_GR23

      DOI: 10.1016/j.cmet.2021.02.001

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    sciencedirect.com/science/article/pii/S1550413121000577
  71. Apr 2021
  72. www.sciencedirect.com www.sciencedirect.com
    Structure-Aided Development of Small-Molecule Inhibitors of ENPP1, the Extracellular Phosphodiesterase of the Immunotransmitter cGAMP
    1
    1. scibot 27 Apr 2021
      RRID:CVCL_GR23

      DOI: 10.1016/j.chembiol.2020.07.007

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    sciencedirect.com/science/article/pii/S2451945620302804
  73. www.sciencedirect.com www.sciencedirect.com
    Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity
    1
    1. scibot 24 Apr 2021
      RRID:CVCL_GR23

      DOI: 10.1016/j.cell.2020.11.009

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    sciencedirect.com/science/article/pii/S0092867420315269
  74. Feb 2021
  75. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Targeting stromal cell Syndecan‐2 reduces breast tumour growth, metastasis and limits immune evasion
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    1. scibot 28 Feb 2021
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      DOI: 10.1002/ijc.33383

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    onlinelibrary.wiley.com/doi/10.1002/ijc.33383
  76. Jan 2021
  77. www.nature.com www.nature.com
    Time-restricted feeding normalizes hyperinsulinemia to inhibit breast cancer in obese postmenopausal mouse models
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    1. scibot 30 Jan 2021
      RRID:CVCL_GR23

      DOI: 10.1038/s41467-020-20743-7

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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanical Loading-Driven Tumor Suppression Is Mediated by Lrp5-Dependent and Independent Mechanisms
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    1. scibot 26 Jan 2021
      RRID:CVCL_GR23

      DOI: 10.3390/cancers13020267

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    ncbi.nlm.nih.gov/pmc/articles/PMC7828232/
  79. Dec 2020
  80. www.sciencedirect.com www.sciencedirect.com
    Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells
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    1. scibot 15 Dec 2020
      RRID:CVCL_GR23

      DOI: 10.1016/j.celrep.2020.108482

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    sciencedirect.com/science/article/pii/S2211124720314716
  81. Nov 2020
  82. www.frontiersin.org www.frontiersin.org
    Obesity-Associated Myeloid-Derived Suppressor Cells Promote Apoptosis of Tumor-Infiltrating CD8 T Cells and Immunotherapy Resistance in Breast Cancer
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    1. scibot 01 Nov 2020
      RRID:CVCL_GR23

      DOI: 10.3389/fimmu.2020.590794

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    frontiersin.org/article/10.3389/fimmu.2020.590794/full
  83. Sep 2020
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WNT1-inducible signaling pathway protein 1 (WISP1/CCN4) stimulates melanoma invasion and metastasis by promoting the epithelial–mesenchymal transition
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    1. scibot 17 Sep 2020
      RRID:CVCL_GR23

      DOI: 10.1074/jbc.RA118.006122

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    ncbi.nlm.nih.gov/pmc/articles/PMC6462510/
  85. onlinelibrary.wiley.com onlinelibrary.wiley.com
    CTLA4 blockade promotes vessel normalization in breast tumors via the accumulation of eosinophils
    1
    1. scibot 15 Sep 2020
      RRID:CVCL_GR23

      DOI: 10.1002/ijc.32829

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    onlinelibrary.wiley.com/doi/10.1002/ijc.32829
  86. www.sciencedirect.com www.sciencedirect.com
    Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity
    1
    1. scibot 13 Sep 2020
      RRID:CVCL_GR23

      DOI: 10.1016/j.cell.2020.02.015

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    sciencedirect.com/science/article/pii/S0092867420301598
  87. www.sciencedirect.com www.sciencedirect.com
    A Model of Differential Mammary Growth Initiation by Stat3 and Asymmetric Integrin-α6 Inheritance
    1
    1. scibot 03 Sep 2020
      RRID:CVCL_GR23

      DOI: 10.1016/j.celrep.2020.02.079

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    sciencedirect.com/science/article/pii/S2211124720302539
  88. Jan 2020
  89. www.sciencedirect.com www.sciencedirect.com
    Contrasting Effects of IGF Binding Protein-3 Expression in Mammary Tumor Cells and the Tumor Microenvironment
    1
    1. scibot 13 Jan 2020
      RRID:CVCL_GR23

      DOI: 10.1016/j.yexcr.2018.11.006

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    sciencedirect.com/science/article/pii/S0014482718308218
  90. Nov 2017
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage PPARγ inhibits Gpr132 to mediate the anti-tumor effects of rosiglitazone
    1
    1. scibot 08 Nov 2017
      CVCL_GR23

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    ncbi.nlm.nih.gov/pmc/articles/PMC5047746/