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40 Matching Annotations

Jan 2026
www.nature.com www.nature.com

Single-cell perturbations decipher ribosomal stress-surveillance regulators in type 2 diabetes

1
1. scibot 06 Jan 2026
  
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  RRID:CVCL_L909
  
  DOI: 10.1038/s42255-025-01407-6
  
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nature.com/articles/s42255-025-01407-6
Sep 2025
www.sciencedirect.com www.sciencedirect.com

The type 1 diabetes candidate genes PTPN2 and BACH2 regulate the IFN-α-induced crosstalk between JAK/STAT and MAPKs pathways in human beta cells

1
1. scibot 19 Sep 2025
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.ebiom.2025.105932
  
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sciencedirect.com/science/article/pii/S2352396425003767
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Identification of novel type 1 and type 2 diabetes genes by co-localization of human islet eQTL and GWAS variants with colocRedRibbon

1
1. scibot 17 Sep 2025
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.xgen.2025.101004
  
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sciencedirect.com/science/article/pii/S2666979X25002605
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8+ T cell activity and biomarker during the evolution of Type 1 Diabetes

1
1. scibot 06 Sep 2025
  
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  RRID:CVCL_L909
  
  DOI: 10.1007/s00125-024-06313-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12276980/
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D-associated genes and regulatory signals

1
1. scibot 30 Jul 2025
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.celrep.2025.116065
  
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sciencedirect.com/science/article/pii/S2211124725008368
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Complete loss of PAX4 causes transient neonatal diabetes in humans

1
1. scibot 22 Jul 2025
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.molmet.2025.102201
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12275979/
Jun 2025
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ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation

1
1. scibot 25 Jun 2025
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.stem.2025.06.002
  
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sciencedirect.com/science/article/pii/S1934590925002243
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VDAC1 is a target for pharmacologically induced insulin hypersecretion in β cells

1
1. scibot 13 Jun 2025
  
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  CVCL_L909
  
  DOI: 10.1016/j.celrep.2025.115834
  
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sciencedirect.com/science/article/pii/S2211124725006059
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Complete Loss of PAX4 causes Transient Neonatal Diabetes in Humans

1
1. scibot 20 May 2025
  
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  RRID:CVCL_L909
  
  DOI: 10.1101/2025.04.01.25324926
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11998800/
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Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice

1
1. scibot 17 May 2025
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.ebiom.2025.105734
  
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sciencedirect.com/science/article/pii/S2352396425001781
Sep 2024
www.biorxiv.org www.biorxiv.org

Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8+ T cell activity and biomarker during the evolution of Type 1 Diabetes

1
1. scibot 28 Sep 2024
  
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  RRID:CVCL_L909
  
  DOI: 10.1101/2024.09.18.613649
  
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biorxiv.org/content/10.1101/2024.09.18.613649v1
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IGFBP7 is upregulated in islets from T2D donors and reduces insulin secretion

1
1. scibot 25 Sep 2024
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.isci.2024.110767
  
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sciencedirect.com/science/article/pii/S2589004224019928
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Stress-induced β cell early senescence confers protection against type 1 diabetes

1
1. scibot 17 Nov 2023
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.cmet.2023.10.014
  
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sciencedirect.com/science/article/pii/S1550413123003832
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Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells

2
1. scibot 02 Nov 2023
  
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  CVCL_L909
  
  DOI: 10.1016/j.cmet.2023.09.013
  
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2. scibot 02 Nov 2023
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.cmet.2023.09.013
  
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sciencedirect.com/science/article/pii/S1550413123003698
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Deucravacitinib, a tyrosine kinase 2 pseudokinase inhibitor, protects human EndoC-βH1 β-cells against proinflammatory insults

1
1. scibot 20 Oct 2023
  
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  RRID:CVCL_L909
  
  DOI: 10.3389/fimmu.2023.1263926
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10579912/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development

1
1. scibot 05 Oct 2023
  
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  RRID:CVCL_L909
  
  DOI: 10.1038/s41467-023-41860-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10542369/
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inferring causal genes at type 2 diabetes GWAS loci through chromosome interactions in islet cells

1
1. scibot 23 Sep 2023
  
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  RRID:CVCL_L909
  
  DOI: 10.12688/wellcomeopenres.18653.2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10509606/
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming

1
1. scibot 27 Jul 2023
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.isci.2023.107231
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10366467/
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways

1
1. scibot 21 Jun 2023
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.cmet.2023.05.007
  
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sciencedirect.com/science/article/pii/S1550413123001845
May 2023
www.biorxiv.org www.biorxiv.org

Functional interrogation of twenty type 2 diabetes-associated genes using isogenic hESC-derived β-like cells

1
1. scibot 18 May 2023
  
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  RRID:CVCL_L909
  
  DOI: 10.1101/2023.05.07.539774
  
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biorxiv.org/content/10.1101/2023.05.07.539774v1
Apr 2023
www.sciencedirect.com www.sciencedirect.com

Glucocorticoid-mediated induction of ZBTB16 affects insulin secretion in human islets and EndoC-βH1 β-cells

1
1. scibot 28 Apr 2023
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.isci.2023.106555
  
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sciencedirect.com/science/article/pii/S2589004223006326
Mar 2023
www.mdpi.com www.mdpi.com

BCL-XL Overexpression Protects Pancreatic β-Cells against Cytokine- and Palmitate-Induced Apoptosis

1
1. scibot 24 Mar 2023
  
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  RRID:CVCL_L909
  
  DOI: 10.3390/ijms24065657
  
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mdpi.com/1422-0067/24/6/5657
May 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

In Vitro Assays to Identify Metabolism-Disrupting Chemicals with Diabetogenic Activity in a Human Pancreatic β-Cell Model

1
1. scibot 18 May 2022
  
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  RRID:CVCL_L909
  
  DOI: 10.3390/ijms23095040
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9102687/
Apr 2022
www.sciencedirect.com www.sciencedirect.com

G protein-coupled estrogen receptor activation by bisphenol-A disrupts the protection from apoptosis conferred by the estrogen receptors ERα and ERβ in pancreatic beta cells

1
1. scibot 20 Apr 2022
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.envint.2022.107250
  
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sciencedirect.com/science/article/pii/S0160412022001763
Mar 2022
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 03 Mar 2022
  
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  RRID:CVCL_L909
  
  DOI: 10.1111/bph.15803
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15803
Feb 2022
www.nature.com www.nature.com

Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture

1
1. scibot 12 Feb 2022
  
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  RRID:CVCL_L909
  
  DOI: 10.1038/s41596-021-00651-w
  
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nature.com/articles/s41596-021-00651-w
Aug 2021
link.springer.com link.springer.com

Untitled document

1
1. scibot 10 Aug 2021
  
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  RRID:CVCL_L909
  
  DOI: 10.1007/s00125-018-4782-0
  
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link.springer.com/article/10.1007/s00125-018-4782-0
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 31 Jul 2021
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.ebiom.2018.09.040
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6197434/
link.springer.com link.springer.com

ZBED6 counteracts high-fat diet-induced glucose intolerance by maintaining beta cell area and reducing excess mitochondrial activation

1
1. scibot 24 Jul 2021
  
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  RRID:CVCL_L909
  
  DOI: 10.1007/s00125-021-05517-0
  
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link.springer.com/article/10.1007/s00125-021-05517-0
Jun 2021
www.sciencedirect.com www.sciencedirect.com

MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity

1
1. scibot 23 Jun 2021
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.bbadis.2021.166199
  
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sciencedirect.com/science/article/pii/S0925443921001320
www.sciencedirect.com www.sciencedirect.com

SARS-CoV-2 infection induces beta cell transdifferentiation

1
1. scibot 05 Jun 2021
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.cmet.2021.05.015
  
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sciencedirect.com/science/article/pii/S1550413121002321
Feb 2021
www.sciencedirect.com www.sciencedirect.com

Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion

1
1. scibot 09 Feb 2021
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.celrep.2021.108703
  
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  RRID:CVCL_L909 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124721000164
Oct 2020
www.sciencedirect.com www.sciencedirect.com

Purification of pancreatic endocrine subsets reveals increased iron metabolism in beta-cells

1
1. scibot 17 Oct 2020
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.molmet.2020.101060
  
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  Curator: @evieth
  
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  RRIDCUR:Validated RRID:CVCL_L909
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sciencedirect.com/science/article/pii/S2212877820301344
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Deep learning models predict regulatory variants in pancreatic islets and refine type 2 diabetes association signals

1
1. scibot 26 Sep 2020
  
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  RRID:CVCL_L909
  
  DOI: 10.7554/eLife.51503
  
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  Curator: @evieth
  
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  RRIDCUR:Validated RRID:CVCL_L909
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ncbi.nlm.nih.gov/pmc/articles/PMC7007221/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The microRNAs miR-211-5p and miR-204-5p modulate ER stress in human beta cells.

1
1. scibot 08 Sep 2020
  
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  RRID:CVCL_L909
  
  DOI: 10.1530/JME-19-0066
  
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  Curator: @evieth
  
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  RRID:CVCL_L909 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6938585/
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_L909
  
  DOI: 10.1016/j.celrep.2018.12.083
  
  Resource: (RRID:CVCL_L909)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_L909
  
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  RRID:CVCL_L909 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124718320436
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Untitled document

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1. scibot 05 Nov 2018
  
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  RRID:CVCL_L909
  
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sciencedirect.com/science/article/pii/S2352396418303980
elifesciences.org elifesciences.org

Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci

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1. scibot 05 Nov 2018
  
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  RRID:CVCL_L909
  
  Curator: @evieth
  
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elifesciences.org/articles/31977
Nov 2017
academic.oup.com academic.oup.com

Protective Role of Complement C3 Against Cytokine-Mediated β-Cell Apoptosis

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1. scibot 08 Nov 2017
  
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  RRID: CVCL_L909
  
  Curator: @kaitlinsung
  
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academic.oup.com/endo/article/158/8/2503/3861370/Protective-Role-of-Complement-C3-Against-Cytokine