109 Matching Annotations
  1. Last 7 days
  2. rupress.org rupress.org
    PEX14 acts as a molecular link between optineurin and the autophagic machinery to induce pexophagy
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    rupress.org/jcb/article/224/11/e202411184/278363/PEX14-acts-as-a-molecular-link-between-optineurin
  3. Oct 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC12501252/
  5. Sep 2025
  6. www.sciencedirect.com www.sciencedirect.com
    Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome
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    sciencedirect.com/science/article/pii/S1097276525007002
  7. Aug 2025
  8. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225016700-main-html.html
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  9. Jul 2025
  10. journals.plos.org journals.plos.org
    Legionella effector LpPIP recruits protein phosphatase 1 to the mitochondria to induce dephosphorylation of outer membrane proteins
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    journals.plos.org/plosbiology/article
  11. Jun 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PDZ-directed substrate recruitment is the primary determinant of specific 4E-BP1 dephosphorylation by PP1-Neurabin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12185105/
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    Machine-guided dual-objective protein engineering for deimmunization and therapeutic functions
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    sciencedirect.com/science/article/pii/S2405471225001322
  14. May 2025
  15. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Proteomics Analysis of the TDP-43 Interactome in Cellular Models of ALS Pathogenesis
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70079
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    Spatiotemporally resolved GPCR interactome uncovers unique mediators of receptor agonism
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    sciencedirect.com/science/article/pii/S2451945625001291
  17. Apr 2025
  18. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225005346-main-html.html
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  19. Mar 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-throughput screening identifies a novel small-molecule modulator of Hsp70 that selectively enhances ubiquitination and degradation of misfolded neuronal NO synthase
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    pmc.ncbi.nlm.nih.gov/articles/PMC11934283/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The BLM-TOP3A-RMI1-RMI2 proximity map reveals that RAD54L2 suppresses sister chromatid exchanges
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    pmc.ncbi.nlm.nih.gov/articles/PMC11894219/
  22. Feb 2025
  23. www.nature.com www.nature.com
    Molecular mechanisms of CAND2 in regulating SCF ubiquitin ligases
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    nature.com/articles/s41467-025-57065-5
  24. Jan 2025
  25. www.sciencedirect.com www.sciencedirect.com
    Convergence of orphan quality control pathways at a ubiquitin chain-elongating ligase
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    sciencedirect.com/science/article/pii/S1097276525000024
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    A microscopy-based screen identifies cellular kinases modulating mitochondrial translation
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    sciencedirect.com/science/article/pii/S2211124724014943
  27. Dec 2024
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLP2 and MIC13 synergistically coordinate MICOS assembly and crista junction formation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11667180/
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    Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles
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    sciencedirect.com/science/article/pii/S1097276524009201
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    m6A sites in the coding region trigger translation-dependent mRNA decay
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    sciencedirect.com/science/article/pii/S1097276524008736
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    Nuclear Factor I family members are key transcription factors regulating gene expression
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    sciencedirect.com/science/article/pii/S1535947624001804
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    Homozygous variant in translocase of outer mitochondrial membrane 7 leads to metabolic reprogramming and microcephalic osteodysplastic dwarfism with moyamoya disease
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    sciencedirect.com/science/article/pii/S2352396424005127
  33. Nov 2024
  34. www.sciencedirect.com www.sciencedirect.com
    STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair
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    sciencedirect.com/science/article/pii/S0092867424012005
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    Redundant pathways for removal of defective RNA polymerase II complexes at a promoter-proximal pause checkpoint
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    sciencedirect.com/science/article/pii/S1097276524008359
  36. Oct 2024
  37. www.sciencedirect.com www.sciencedirect.com
    Pervasive mislocalization of pathogenic coding variants underlying human disorders
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    sciencedirect.com/science/article/pii/S0092867424010213
  38. Sep 2024
  39. www.biorxiv.org www.biorxiv.org
    The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain
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    biorxiv.org/content/10.1101/2024.09.10.612325v1
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    C2H2-zinc-finger transcription factors bind RNA and function in diverse post-transcriptional regulatory processes
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    sciencedirect.com/science/article/pii/S1097276524007330
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    Multi-omics analysis using antibody-based in situ biotinylation technique suggests the mechanism of Cajal body formation
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    sciencedirect.com/science/article/pii/S2211124724010854
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    Paraspeckle-independent co-transcriptional regulation of nuclear microRNA biogenesis by SFPQ
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    sciencedirect.com/science/article/pii/S2211124724010465
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DMDA-PatA mediates RNA sequence-selective translation repression by anchoring eIF4A and DDX3 to GNG motifs
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369270/
  44. Aug 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subtype-Specific Ligand Binding and Activation Gating in Homomeric and Heteromeric P2X Receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11352409/
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    Nuclear PKM2 binds pre-mRNA at folded G-quadruplexes and reveals their gene regulatory role
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    sciencedirect.com/science/article/pii/S1097276524006233
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    The ribosomal protein L22 binds the MDM4 pre-mRNA and promotes exon skipping to activate p53 upon nucleolar stress
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    sciencedirect.com/science/article/pii/S2211124724009604
  48. Jul 2024
  49. www.sciencedirect.com www.sciencedirect.com
    Assembly mechanism of Integrator’s RNA cleavage module
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    sciencedirect.com/science/article/pii/S1097276524005392
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA
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    ncbi.nlm.nih.gov/pmc/articles/PMC11265796/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The molecular basis of tRNA selectivity by human pseudouridine synthase 3
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    ncbi.nlm.nih.gov/pmc/articles/PMC11258540/
  52. www.biorxiv.org www.biorxiv.org
    Functional implications of the interaction of the SARS-CoV-2 Nucleocapsid protein with factors involved in nonsense-mediated mRNA decay
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    biorxiv.org/content/10.1101/2024.07.16.603698v1
  53. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Bioisosteric analogs of MDMA: Improving the pharmacological profile?
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16149
  54. May 2024
  55. www.sciencedirect.com www.sciencedirect.com
    Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism
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    sciencedirect.com/science/article/pii/S1097276524003290
  56. Apr 2024
  57. www.biorxiv.org www.biorxiv.org
    The BLM-TOP3A-RMI1-RMI2 proximity map reveals that RAD54L2 suppresses sister chromatid exchanges
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    biorxiv.org/content/10.1101/2024.04.07.588476v1
  58. www.sciencedirect.com www.sciencedirect.com
    Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates
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    sciencedirect.com/science/article/pii/S2211124724003929
  59. Jan 2024
  60. www.nature.com www.nature.com
    CAND1 inhibits Cullin-2-RING ubiquitin ligases for enhanced substrate specificity
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    nature.com/articles/s41594-023-01167-5
  61. Dec 2023
  62. www.sciencedirect.com www.sciencedirect.com
    Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies
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    sciencedirect.com/science/article/pii/S1097276523009723
  63. Jul 2023
  64. www.sciencedirect.com www.sciencedirect.com
    Mechanism of orphan subunit recognition during assembly quality control
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    sciencedirect.com/science/article/pii/S0092867423006943
  65. Jun 2023
  66. www.sciencedirect.com www.sciencedirect.com
    Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation
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    sciencedirect.com/science/article/pii/S1097276523003763
  67. www.embopress.org www.embopress.org
    Human Tim8a, Tim8b and Tim13 are auxiliary assembly factors of mature Complex IV
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    embopress.org/doi/10.15252/embr.202256430
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Coupled protein quality control during nonsense-mediated mRNA decay
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    ncbi.nlm.nih.gov/pmc/articles/PMC10234110/
  69. Apr 2023
  70. www.sciencedirect.com www.sciencedirect.com
    Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair
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    sciencedirect.com/science/article/pii/S1097276523002113
  71. www.nature.com www.nature.com
    Glucocerebrosidase is imported into mitochondria and preserves complex I integrity and energy metabolism
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    nature.com/articles/s41467-023-37454-4
  72. Mar 2023
  73. www.sciencedirect.com www.sciencedirect.com
    A central chaperone-like role for 14-3-3 proteins in human cells
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    sciencedirect.com/science/article/pii/S1097276523001211
  74. Jan 2023
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9574375/
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    Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome
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    sciencedirect.com/science/article/pii/S0969212622004889
  77. www.nature.com www.nature.com
    Human mitochondria require mtRF1 for translation termination at non-canonical stop codons
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    nature.com/articles/s41467-022-35684-6
  78. Oct 2022
  79. www.sciencedirect.com www.sciencedirect.com
    ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins
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    sciencedirect.com/science/article/pii/S109727652200956X
  80. Sep 2022
  81. www.embopress.org www.embopress.org
    Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair
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    embopress.org/doi/10.15252/embr.202154136
  82. Aug 2022
  83. www.sciencedirect.com www.sciencedirect.com
    N1-methylpseudouridine found within COVID-19 mRNA vaccines produces faithful protein products
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    sciencedirect.com/science/article/pii/S2211124722011202
  84. Jun 2022
  85. academic.oup.com academic.oup.com
    Exon junction complex-associated multi-adapter RNPS1 nucleates splicing regulatory complexes to maintain transcriptome surveillance
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    academic.oup.com/nar/article/50/10/5899/6595294
  86. www.sciencedirect.com www.sciencedirect.com
    The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability
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    sciencedirect.com/science/article/pii/S009286742200592X
  87. www.sciencedirect.com www.sciencedirect.com
    Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine
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    sciencedirect.com/science/article/pii/S109727652200483X
  88. Apr 2022
  89. www.embopress.org www.embopress.org
    Human UPF3A and UPF3B enable fault-tolerant activation of nonsense-mediated mRNA decay
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    embopress.org/doi/abs/10.15252/embj.2021109191
  90. diabetesjournals.org diabetesjournals.org
    Sulfated Progesterone Metabolites That Enhance Insulin Secretion Via Trpm3 are Reduced in Serum From Women with Gestational Diabetes Mellitus
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    diabetesjournals.org/diabetes/article/71/4/837/141009/Sulfated-Progesterone-Metabolites-That-Enhance
  91. Dec 2021
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes
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    ncbi.nlm.nih.gov/pmc/articles/PMC8654371/
  93. Aug 2021
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Processing of the ribosomal ubiquitin-like fusion protein FUBI-eS30/FAU is required for 40S maturation and depends on USP36
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    ncbi.nlm.nih.gov/pmc/articles/PMC8354635/
  95. www.jneurosci.org www.jneurosci.org
    Promiscuous G-protein coupled receptor inhibition of transient receptor potential melastatin 3 ion channels by Gβγ subunits
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    jneurosci.org/content/39/40/7840
  96. elifesciences.org elifesciences.org
    Untitled document
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    elifesciences.org/articles/21470
  97. www.sciencedirect.com www.sciencedirect.com
    Cand1-Mediated Adaptive Exchange Mechanism Enables Variation in F-Box Protein Expression
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    sciencedirect.com/science/article/pii/S1097276518300972
  98. www.sciencedirect.com www.sciencedirect.com
    The Exon Junction Complex Undergoes a Compositional Switch that Alters mRNP Structure and Nonsense-Mediated mRNA Decay Activity
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    sciencedirect.com/science/article/pii/S2211124718318096
  99. www.nature.com www.nature.com
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    nature.com/articles/s41596-019-0152-8
  100. www.sciencedirect.com www.sciencedirect.com
    System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection
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    sciencedirect.com/science/article/pii/S1097276519300371
  101. www.sciencedirect.com www.sciencedirect.com
    MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition
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    sciencedirect.com/science/article/pii/S2211124719312847
  102. Jul 2021
  103. www.sciencedirect.com www.sciencedirect.com
    Exon Junction Complexes Suppress Spurious Splice Sites to Safeguard Transcriptome Integrity
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    sciencedirect.com/science/article/pii/S1097276518306907
  104. www.sciencedirect.com www.sciencedirect.com
    Lysozyme Counteracts β-Lactam Antibiotics by Promoting the Emergence of L-Form Bacteria
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    sciencedirect.com/science/article/pii/S0092867418300588
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6335053/
  106. www.sciencedirect.com www.sciencedirect.com
    An optogenetic proximity labeling approach to probe the composition of inducible biomolecular condensates in cultured cells
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    sciencedirect.com/science/article/pii/S2666166721003841
  107. www.nature.com www.nature.com
    SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity
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    nature.com/articles/s41467-021-24046-3
  108. May 2021
  109. elifesciences.org elifesciences.org
    Endogenous p53 expression in human and mouse is not regulated by its 3′UTR
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    elifesciences.org/articles/65700
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The final step of 40S ribosomal subunit maturation is controlled by a dual key lock
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    ncbi.nlm.nih.gov/pmc/articles/PMC8112863/
  111. www.sciencedirect.com www.sciencedirect.com
    TopBP1 assembles nuclear condensates to switch on ATR signaling
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    sciencedirect.com/science/article/pii/S1097276520309916
  112. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Regulation of DNA Repair Pathway Choice by MacroH2A1 Splice Variants Ensures Genome Stability
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    sciencedirect.com/science/article/pii/S1097276520304305
  113. Mar 2021
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
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    ncbi.nlm.nih.gov/pmc/articles/PMC7932109/
  115. Feb 2021
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limiting RyR2 Open Time Prevents Alzheimer’s Disease-Related Neuronal Hyperactivity and Memory Loss but Not β-Amyloid Accumulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7532726/
  117. Nov 2020
  118. elifesciences.org elifesciences.org
    SON and SRRM2 are essential for nuclear speckle formation
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    elifesciences.org/articles/60579
  119. Sep 2020
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limiting RyR2 Open Time Prevents Alzheimer’s Disease-Related Neuronal Hyperactivity and Memory Loss but Not β-Amyloid Accumulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7532726/
  121. www.nature.com www.nature.com
    A multi-omics analysis reveals the unfolded protein response regulon and stress-induced resistance to folate-based antimetabolites
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    nature.com/articles/s41467-020-16747-y
  122. elifesciences.org elifesciences.org
    EDF1 coordinates cellular responses to ribosome collisions
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    elifesciences.org/articles/58828
  123. www.sciencedirect.com www.sciencedirect.com
    The Alazami Syndrome-Associated Protein LARP7 Guides U6 Small Nuclear RNA Modification and Contributes to Splicing Robustness
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    sciencedirect.com/science/article/pii/S1097276520300010
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ribosome collisions trigger cis-acting feedback inhibition of translation initiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7381030/
  125. www.nature.com www.nature.com
    Using TT chem -seq for profiling nascent transcription and measuring transcript elongation
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