88 Matching Annotations
  1. Last 7 days
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    STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair
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    1. scibot 21 Nov 2024
      Cat#R78007

      DOI: 10.1016/j.cell.2024.10.018

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    sciencedirect.com/science/article/pii/S0092867424012005
  3. Nov 2024
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    Redundant pathways for removal of defective RNA polymerase II complexes at a promoter-proximal pause checkpoint
    1
    1. scibot 15 Nov 2024
      R78007

      DOI: 10.1016/j.molcel.2024.10.012

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    sciencedirect.com/science/article/pii/S1097276524008359
  5. Oct 2024
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    Pervasive mislocalization of pathogenic coding variants underlying human disorders
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    1. scibot 02 Oct 2024
      RRID:CVCL_U427

      DOI: 10.1016/j.cell.2024.09.003

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    sciencedirect.com/science/article/pii/S0092867424010213
  7. Sep 2024
  8. www.biorxiv.org www.biorxiv.org
    The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain
    1
    1. scibot 29 Sep 2024
      RRID:CVCL_U427

      DOI: 10.1101/2024.09.10.612325

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    biorxiv.org/content/10.1101/2024.09.10.612325v1
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    C2H2-zinc-finger transcription factors bind RNA and function in diverse post-transcriptional regulatory processes
    1
    1. scibot 25 Sep 2024
      R780-07

      DOI: 10.1016/j.molcel.2024.08.037

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    sciencedirect.com/science/article/pii/S1097276524007330
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    Multi-omics analysis using antibody-based in situ biotinylation technique suggests the mechanism of Cajal body formation
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    1. scibot 17 Sep 2024
      R78007

      DOI: 10.1016/j.celrep.2024.114734

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    sciencedirect.com/science/article/pii/S2211124724010854
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    Paraspeckle-independent co-transcriptional regulation of nuclear microRNA biogenesis by SFPQ
    1
    1. scibot 10 Sep 2024
      Cat#: R78007

      DOI: 10.1016/j.celrep.2024.114695

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    sciencedirect.com/science/article/pii/S2211124724010465
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DMDA-PatA mediates RNA sequence-selective translation repression by anchoring eIF4A and DDX3 to GNG motifs
    1
    1. scibot 05 Sep 2024
      R78007

      DOI: 10.1038/s41467-024-51635-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC11369270/
  13. Aug 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subtype-Specific Ligand Binding and Activation Gating in Homomeric and Heteromeric P2X Receptors
    1
    1. scibot 30 Aug 2024
      Flp-In-T-REx 293

      DOI: 10.3390/biom14080942

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    ncbi.nlm.nih.gov/pmc/articles/PMC11352409/
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    Nuclear PKM2 binds pre-mRNA at folded G-quadruplexes and reveals their gene regulatory role
    1
    1. scibot 20 Aug 2024
      R78007

      DOI: 10.1016/j.molcel.2024.07.025

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    sciencedirect.com/science/article/pii/S1097276524006233
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    The ribosomal protein L22 binds the MDM4 pre-mRNA and promotes exon skipping to activate p53 upon nucleolar stress
    1
    1. scibot 20 Aug 2024
      RRID:CVCL_U427

      DOI: 10.1016/j.celrep.2024.114610

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    sciencedirect.com/science/article/pii/S2211124724009604
  17. Jul 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Assembly mechanism of Integrator’s RNA cleavage module
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    1. scibot 27 Jul 2024
      Cat# R78007

      DOI: 10.1016/j.molcel.2024.06.032

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    sciencedirect.com/science/article/pii/S1097276524005392
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA
    1
    1. scibot 26 Jul 2024
      CVCL_U427

      DOI: 10.7554/eLife.91783

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    ncbi.nlm.nih.gov/pmc/articles/PMC11265796/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The molecular basis of tRNA selectivity by human pseudouridine synthase 3
    1
    1. scibot 23 Jul 2024
      RRID:CVCL_U427

      DOI: 10.1016/j.molcel.2024.06.013

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    ncbi.nlm.nih.gov/pmc/articles/PMC11258540/
  21. www.biorxiv.org www.biorxiv.org
    Functional implications of the interaction of the SARS-CoV-2 Nucleocapsid protein with factors involved in nonsense-mediated mRNA decay
    1
    1. scibot 23 Jul 2024
      RRID:CVCL_U427

      DOI: 10.1101/2024.07.16.603698

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    biorxiv.org/content/10.1101/2024.07.16.603698v1
  22. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Bioisosteric analogs of MDMA: Improving the pharmacological profile?
    1
    1. scibot 18 Jul 2024
      RRID:CVCL_U427

      DOI: 10.1111/jnc.16149

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16149
  23. May 2024
  24. www.sciencedirect.com www.sciencedirect.com
    Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism
    1
    1. scibot 17 May 2024
      RRID:CVCL_U427

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    sciencedirect.com/science/article/pii/S1097276524003290
  25. Apr 2024
  26. www.biorxiv.org www.biorxiv.org
    The BLM-TOP3A-RMI1-RMI2 proximity map reveals that RAD54L2 suppresses sister chromatid exchanges
    1
    1. scibot 12 Apr 2024
      RRID:CVCL_U427

      DOI: 10.1101/2024.04.07.588476

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    biorxiv.org/content/10.1101/2024.04.07.588476v1
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    Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates
    2
    1. scibot 09 Apr 2024
      RRID:CVCL_U427

      DOI: 10.1016/j.celrep.2024.114064

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    2. scibot 09 Apr 2024
      RRID:CVCL_U427

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    sciencedirect.com/science/article/pii/S2211124724003929
  28. Jan 2024
  29. www.nature.com www.nature.com
    CAND1 inhibits Cullin-2-RING ubiquitin ligases for enhanced substrate specificity
    1
    1. scibot 11 Jan 2024
      RRID:CVCL_U427

      DOI: 10.1038/s41594-023-01167-5

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    nature.com/articles/s41594-023-01167-5
  30. Dec 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies
    1
    1. scibot 19 Dec 2023
      RRID:CVCL_U427

      DOI: 10.1016/j.molcel.2023.11.027

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    sciencedirect.com/science/article/pii/S1097276523009723
  32. Jul 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Mechanism of orphan subunit recognition during assembly quality control
    1
    1. scibot 22 Jul 2023
      RRID:CVCL_U427

      DOI: 10.1016/j.cell.2023.06.016

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    sciencedirect.com/science/article/pii/S0092867423006943
  34. Jun 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation
    1
    1. scibot 09 Jun 2023
      RRID:CVCL_U427

      DOI: 10.1016/j.molcel.2023.05.020

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    sciencedirect.com/science/article/pii/S1097276523003763
  36. www.embopress.org www.embopress.org
    Human Tim8a, Tim8b and Tim13 are auxiliary assembly factors of mature Complex IV
    1
    1. scibot 06 Jun 2023
      RRID:CVCL_U427

      DOI: 10.15252/embr.202256430

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    embopress.org/doi/10.15252/embr.202256430
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Coupled protein quality control during nonsense-mediated mRNA decay
    1
    1. scibot 03 Jun 2023
      RRID:CVCL_U427

      DOI: 10.1242/jcs.261216

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    ncbi.nlm.nih.gov/pmc/articles/PMC10234110/
  38. Apr 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair
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    1. scibot 14 Apr 2023
      RRID:CVCL_U427

      DOI: 10.1016/j.molcel.2023.03.021

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    sciencedirect.com/science/article/pii/S1097276523002113
  40. www.nature.com www.nature.com
    Glucocerebrosidase is imported into mitochondria and preserves complex I integrity and energy metabolism
    1
    1. scibot 11 Apr 2023
      RRID:CVCL_U427

      DOI: 10.1038/s41467-023-37454-4

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    nature.com/articles/s41467-023-37454-4
  41. Mar 2023
  42. www.sciencedirect.com www.sciencedirect.com
    A central chaperone-like role for 14-3-3 proteins in human cells
    1
    1. scibot 17 Mar 2023
      RRID:CVCL_U427

      DOI: 10.1016/j.molcel.2023.02.018

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    sciencedirect.com/science/article/pii/S1097276523001211
  43. Jan 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis
    1
    1. scibot 12 Jan 2023
      RRID:CVCL_U427

      DOI: 10.1158/0008-5472.CAN-22-0834

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    ncbi.nlm.nih.gov/pmc/articles/PMC9574375/
  45. www.sciencedirect.com www.sciencedirect.com
    Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome
    1
    1. scibot 04 Jan 2023
      RRID:CVCL_U427

      DOI: 10.1016/j.str.2022.12.002

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    sciencedirect.com/science/article/pii/S0969212622004889
  46. www.nature.com www.nature.com
    Human mitochondria require mtRF1 for translation termination at non-canonical stop codons
    1
    1. scibot 04 Jan 2023
      RRID:CVCL_U427

      DOI: 10.1038/s41467-022-35684-6

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    nature.com/articles/s41467-022-35684-6
  47. Oct 2022
  48. www.sciencedirect.com www.sciencedirect.com
    ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins
    1
    1. scibot 25 Oct 2022
      RRID:CVCL_U427

      DOI: 10.1016/j.molcel.2022.09.035

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    sciencedirect.com/science/article/pii/S109727652200956X
  49. Sep 2022
  50. www.embopress.org www.embopress.org
    Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair
    1
    1. scibot 29 Sep 2022
      RRID:CVCL_U427

      DOI: 10.15252/embr.202154136

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    embopress.org/doi/10.15252/embr.202154136
  51. Aug 2022
  52. www.sciencedirect.com www.sciencedirect.com
    N1-methylpseudouridine found within COVID-19 mRNA vaccines produces faithful protein products
    1
    1. scibot 23 Aug 2022
      RRID:CVCL_U427

      DOI: 10.1016/j.celrep.2022.111300

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    sciencedirect.com/science/article/pii/S2211124722011202
  53. Jun 2022
  54. academic.oup.com academic.oup.com
    Exon junction complex-associated multi-adapter RNPS1 nucleates splicing regulatory complexes to maintain transcriptome surveillance
    1
    1. scibot 11 Jun 2022
      RRID:CVCL_U427

      DOI: 10.1093/nar/gkac428

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    academic.oup.com/nar/article/50/10/5899/6595294
  55. www.sciencedirect.com www.sciencedirect.com
    The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability
    1
    1. scibot 10 Jun 2022
      RRID:CVCL_U427

      DOI: 10.1016/j.cell.2022.05.008

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    sciencedirect.com/science/article/pii/S009286742200592X
  56. www.sciencedirect.com www.sciencedirect.com
    Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine
    1
    1. scibot 09 Jun 2022
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      DOI: 10.1016/j.molcel.2022.05.016

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    sciencedirect.com/science/article/pii/S109727652200483X
  57. Apr 2022
  58. www.embopress.org www.embopress.org
    Human UPF3A and UPF3B enable fault-tolerant activation of nonsense-mediated mRNA decay
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    1. scibot 27 Apr 2022
      RRID:CVCL_U427

      DOI: 10.15252/embj.2021109191

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    embopress.org/doi/abs/10.15252/embj.2021109191
  59. diabetesjournals.org diabetesjournals.org
    Sulfated Progesterone Metabolites That Enhance Insulin Secretion Via Trpm3 are Reduced in Serum From Women with Gestational Diabetes Mellitus
    1
    1. scibot 06 Apr 2022
      RRID:CVCL_U427

      DOI: 10.2337/db21-0702

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    diabetesjournals.org/diabetes/article/71/4/837/141009/Sulfated-Progesterone-Metabolites-That-Enhance
  60. Dec 2021
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes
    1
    1. scibot 11 Dec 2021
      RRID:CVCL_U427

      DOI: 10.7554/eLife.70504

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    ncbi.nlm.nih.gov/pmc/articles/PMC8654371/
  62. Aug 2021
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Processing of the ribosomal ubiquitin-like fusion protein FUBI-eS30/FAU is required for 40S maturation and depends on USP36
    1
    1. scibot 16 Aug 2021
      RRID:CVCL_U427

      DOI: 10.7554/eLife.70560

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  64. www.jneurosci.org www.jneurosci.org
    Promiscuous G-protein coupled receptor inhibition of transient receptor potential melastatin 3 ion channels by Gβγ subunits
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  65. elifesciences.org elifesciences.org
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  66. www.sciencedirect.com www.sciencedirect.com
    Cand1-Mediated Adaptive Exchange Mechanism Enables Variation in F-Box Protein Expression
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  67. www.sciencedirect.com www.sciencedirect.com
    The Exon Junction Complex Undergoes a Compositional Switch that Alters mRNP Structure and Nonsense-Mediated mRNA Decay Activity
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  68. www.nature.com www.nature.com
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  69. www.sciencedirect.com www.sciencedirect.com
    System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection
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  70. www.sciencedirect.com www.sciencedirect.com
    MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition
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  71. Jul 2021
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    Exon Junction Complexes Suppress Spurious Splice Sites to Safeguard Transcriptome Integrity
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  73. www.sciencedirect.com www.sciencedirect.com
    Lysozyme Counteracts β-Lactam Antibiotics by Promoting the Emergence of L-Form Bacteria
    2
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  75. www.sciencedirect.com www.sciencedirect.com
    An optogenetic proximity labeling approach to probe the composition of inducible biomolecular condensates in cultured cells
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  76. www.nature.com www.nature.com
    SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity
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  77. May 2021
  78. elifesciences.org elifesciences.org
    Endogenous p53 expression in human and mouse is not regulated by its 3′UTR
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The final step of 40S ribosomal subunit maturation is controlled by a dual key lock
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  80. www.sciencedirect.com www.sciencedirect.com
    TopBP1 assembles nuclear condensates to switch on ATR signaling
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  81. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Regulation of DNA Repair Pathway Choice by MacroH2A1 Splice Variants Ensures Genome Stability
    1
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  82. Mar 2021
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
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  84. Feb 2021
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limiting RyR2 Open Time Prevents Alzheimer’s Disease-Related Neuronal Hyperactivity and Memory Loss but Not β-Amyloid Accumulation
    1
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  86. Nov 2020
  87. elifesciences.org elifesciences.org
    SON and SRRM2 are essential for nuclear speckle formation
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  88. Sep 2020
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limiting RyR2 Open Time Prevents Alzheimer’s Disease-Related Neuronal Hyperactivity and Memory Loss but Not β-Amyloid Accumulation
    1
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  90. www.nature.com www.nature.com
    A multi-omics analysis reveals the unfolded protein response regulon and stress-induced resistance to folate-based antimetabolites
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  91. elifesciences.org elifesciences.org
    EDF1 coordinates cellular responses to ribosome collisions
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  92. www.sciencedirect.com www.sciencedirect.com
    The Alazami Syndrome-Associated Protein LARP7 Guides U6 Small Nuclear RNA Modification and Contributes to Splicing Robustness
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ribosome collisions trigger cis-acting feedback inhibition of translation initiation
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  94. www.nature.com www.nature.com
    Using TT chem -seq for profiling nascent transcription and measuring transcript elongation
    1
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  95. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  96. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Multiplex Cell Fate Tracking by Flow Cytometry
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  97. www.sciencedirect.com www.sciencedirect.com
    Dissecting the Roles of Mitochondrial Complex I Intermediate Assembly Complex Factors in the Biogenesis of Complex I
    1
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  98. www.nature.com www.nature.com
    Combined proximity labeling and affinity purification−mass spectrometry workflow for mapping and visualizing protein interaction networks
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      DOI: 10.1038/s41596-020-0365-x

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  99. Jan 2020
  100. www.sciencedirect.com www.sciencedirect.com
    An Oxygen-Dependent Interaction between FBXL5 and the CIA-Targeting Complex Regulates Iron Homeostasis
    1
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Misfolded GPI-anchored proteins are escorted through the secretory pathway by ER-derived factors
    1
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  102. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  104. Nov 2018
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  107. www.sciencedirect.com www.sciencedirect.com
    Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death
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  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  109. www.sciencedirect.com www.sciencedirect.com
    Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment
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  110. www.sciencedirect.com www.sciencedirect.com
    Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions
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  111. Nov 2017
  112. elifesciences.org elifesciences.org
    G protein βγ subunits inhibit TRPM3 ion channels in sensory neurons
    1
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  113. www.sciencedirect.com www.sciencedirect.com
    TTC19 Plays a Husbandry Role on UQCRFS1 Turnover in the Biogenesis of Mitochondrial Respiratory Complex III
    1
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      Flp-In T-REx 293 Cell Line

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  114. www.sciencedirect.com www.sciencedirect.com
    Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex
    1
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    sciencedirect.com/science/article/pii/S1097276517304410
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EMC1-dependent stabilization drives membrane penetration of a partially destabilized non-enveloped virus
    1
    1. scibot 08 Nov 2017
      CVCL_U427

      Curator: @gabimpine

      Resource used:

      RRID:CVCL_U427

      SciCrunch record: RRID:CVCL_U427

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:CVCL_U427 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC5224922/
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability
    1
    1. scibot 08 Nov 2017
      CVCL_U427

      Curator: @gabimpine

      Resource used:

      RRID:CVCL_U427

      SciCrunch record: RRID:CVCL_U427

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:CVCL_U427 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC5016092/
  117. www.sciencedirect.com www.sciencedirect.com
    Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation
    1
    1. scibot 08 Nov 2017
      CVCL_U427

      Curator: @gabimpine

      Resource used:

      RRID:CVCL_U427

      SciCrunch record: RRID:CVCL_U427

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:CVCL_U427 RRIDCUR:Validated
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    URL

    sciencedirect.com/science/article/pii/S0092867416309734