82 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes
    1
    1. scibot 14 Nov 2024
      C631

      DOI: 10.1016/j.cell.2024.10.027

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    sciencedirect.com/science/article/pii/S0092867424012091
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for CSNK2A1 (UniProt ID: P68400) for use in western blot, immunoprecipitation and immunofluorescence
    1
    1. scibot 07 Nov 2024
      CVCL_Y019

      DOI: 10.12688/f1000research.153243.2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11472280/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
    1
    1. scibot 07 Nov 2024
      RRID:CVCL_Y019

      DOI: 10.1158/1535-7163.MCT-23-0487

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    pmc.ncbi.nlm.nih.gov/articles/PMC11286238/
  5. Oct 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for amyloid-beta precursor protein for use in Western Blot, immunoprecipitation and immunofluorescence
    1
    1. scibot 04 Oct 2024
      CVCL_Y019

      DOI: 10.12688/f1000research.139867.2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11445640/
  7. Sep 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Saturation mutagenesis-reinforced functional assays for disease-related genes
    1
    1. scibot 27 Sep 2024
      C631

      DOI: 10.1016/j.cell.2024.08.047

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    sciencedirect.com/science/article/pii/S0092867424009760
  9. Aug 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for human Midkine for use in Western blot and immunoprecipitation
    1
    1. scibot 18 Aug 2024
      CVCL_Y019

      DOI: 10.12688/f1000research.130587.3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11292187/
  11. www.cell.com www.cell.com
    Genome-scale exon perturbation screens uncover exons critical for cell fitness
    1
    1. scibot 13 Aug 2024
      C631

      DOI: 10.1016/j.molcel.2024.05.024

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    cell.com/molecular-cell/abstract/S1097-2765(24)00447-7
  12. Jul 2024
  13. www.biorxiv.org www.biorxiv.org
    Click-chemistry-aided quantitation and sequencing of oxidized guanines and apurinic sites uncovers their transcription-linked strand bias in human cells
    1
    1. scibot 30 Jul 2024
      RRID:CVCL_Y019

      DOI: 10.1101/2024.07.21.604463

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    biorxiv.org/content/10.1101/2024.07.21.604463v1
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Host cell CRISPR genomics and modelling reveal shared metabolic vulnerabilities in the intracellular development of Plasmodium falciparum and related hemoparasites
    1
    1. scibot 25 Jul 2024
      RRID:CVCL_Y019

      DOI: 10.1038/s41467-024-50405-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11271486/
  15. www.sciencedirect.com www.sciencedirect.com
    Efficient, specific, and combinatorial control of endogenous exon splicing with dCasRx-RBM25
    1
    1. scibot 24 Jul 2024
      C631

      DOI: 10.1016/j.molcel.2024.05.028

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    sciencedirect.com/science/article/pii/S1097276524004751
  16. www.sciencedirect.com www.sciencedirect.com
    Lack of mismatch repair enhances resistance to methylating agents for cells deficient in oxidative demethylation
    1
    1. scibot 24 Jul 2024
      HAP1

      DOI: 10.1016/j.jbc.2024.107492

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    sciencedirect.com/science/article/pii/S0021925824019938
  17. www.sciencedirect.com www.sciencedirect.com
    The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation
    1
    1. scibot 17 Jul 2024
      RRID:CVCL_Y019

      DOI: 10.1016/j.celrep.2024.114417

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    sciencedirect.com/science/article/pii/S2211124724007460
  18. www.sciencedirect.com www.sciencedirect.com
    Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1
    1
    1. scibot 12 Jul 2024
      RRID:CVCL_Y019

      DOI: 10.1016/j.molcel.2024.06.016

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    sciencedirect.com/science/article/pii/S1097276524005239
  19. Jun 2024
  20. www.nature.com www.nature.com
    Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
    1
    1. scibot 28 Jun 2024
      RRID:CVCL_Y019

      DOI: 10.1038/s41594-024-01338-y

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    nature.com/articles/s41594-024-01338-y
  21. link.springer.com link.springer.com
    Electro-elution-based purification of covalent DNA–protein cross-links
    1
    1. scibot 28 Jun 2024
      RRID:CVCL_Y019

      DOI: 10.1038/s41596-024-01004-z

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    link.springer.com/article/10.1038/s41596-024-01004-z
  22. www.nature.com www.nature.com
    Integrating genome-wide CRISPR screens and in silico drug profiling for targeted antidote development
    1
    1. scibot 06 Jun 2024
      RRID:CVCL_Y019

      DOI: 10.1038/s41596-024-00995-z

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    nature.com/articles/s41596-024-00995-z
  23. May 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of high-performing antibodies for the reliable detection of Tau proteoforms by Western blotting and immunohistochemistry
    1
    1. scibot 22 May 2024
      RRID:CVCL_Y019

      DOI: 10.1007/s00401-024-02729-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11102361/
  25. Apr 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for RNA-binding protein TIA1 for use in Western Blot, immunoprecipitation and immunofluorescence
    1
    1. scibot 20 Apr 2024
      CVCL_Y019

      DOI: 10.12688/f1000research.133645.2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11024596/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Type I interferon regulation by USP18 is a key vulnerability in cancer
    1
    1. scibot 20 Apr 2024
      RRID:CVCL_Y019

      DOI: 10.1016/j.isci.2024.109593

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    ncbi.nlm.nih.gov/pmc/articles/PMC11022047/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early recovery of proteasome activity in cells pulse-treated with proteasome inhibitors is independent of DDI2
    1
    1. scibot 18 Apr 2024
      RRID:CVCL_Y019

      DOI: 10.7554/eLife.91678

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    ncbi.nlm.nih.gov/pmc/articles/PMC11018354/
  29. www.biorxiv.org www.biorxiv.org
    Fragility of ER homeostatic regulation underlies haploid instability in human somatic cells
    1
    1. scibot 12 Apr 2024
      RRID:CVCL_Y019

      DOI: 10.1101/2024.04.05.588249

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    biorxiv.org/content/10.1101/2024.04.05.588249v1
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for Rab1A and Rab1B for use in Western Blot, immunoprecipitation and immunofluorescence
    1
    1. scibot 03 Apr 2024
      CVCL_Y019

      DOI: 10.12688/f1000research.143928.2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10979127/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator
    1
    1. scibot 03 Apr 2024
      RRID:CVCL_Y019

      DOI: 10.1021/acs.jmedchem.3c02245

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983002/
  32. Mar 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of high-performing antibodies for Vacuolar protein sorting-associated protein 35 (hVPS35) for use in Western Blot, immunoprecipitation and immunofluorescence
    1
    1. scibot 06 Mar 2024
      CVCL_Y019

      DOI: 10.12688/f1000research.133696.2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10905012/
  34. Feb 2024
  35. www.sciencedirect.com www.sciencedirect.com
    Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
    1
    1. scibot 21 Feb 2024
      RRID:CVCL_Y019

      DOI: 10.1016/j.molcel.2024.01.022

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    sciencedirect.com/science/article/pii/S1097276524000893
  36. www.biorxiv.org www.biorxiv.org
    qTAG: An adaptable CRISPR-based endogenous tagging protocol using optimized repair cassettes.
    1
    1. scibot 04 Feb 2024
      RRID:CVCL_Y019

      DOI: 10.1101/2023.11.01.565029

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    biorxiv.org/content/10.1101/2023.11.01.565029v2
  37. dx.doi.org dx.doi.org
    Functional assay for assessment of pathogenicity of BAP1 variants
    1
    1. scibot 03 Feb 2024
      RRID:CVCL_Y019

      DOI: 10.1093/hmg/ddad193

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    dx.doi.org/10.1093/hmg/ddad193
  38. Jan 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of high-performing antibodies for Apolipoprotein E for use in Western Blot and immunoprecipitation
    1
    1. scibot 05 Jan 2024
      CVCL_Y019

      DOI: 10.12688/f1000research.133899.3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10755264/
  40. Dec 2023
  41. www.nature.com www.nature.com
    Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype
    1
    1. scibot 02 Dec 2023
      RRID:CVCL_Y019

      DOI: 10.1038/s41467-023-43657-6

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    nature.com/articles/s41467-023-43657-6
  42. Nov 2023
  43. www.sciencedirect.com www.sciencedirect.com
    RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks
    1
    1. scibot 28 Nov 2023
      RRID:CVCL_Y019

      DOI: 10.1016/j.molcel.2023.10.012

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    sciencedirect.com/science/article/pii/S1097276523008493
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12
    1
    1. scibot 15 Nov 2023
      RRID:CVCL_Y019

      DOI: 10.1126/scisignal.adg0485

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    ncbi.nlm.nih.gov/pmc/articles/PMC10639087/
  45. Oct 2023
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity
    1
    1. scibot 31 Oct 2023
      RRID:CVCL_Y019

      DOI: 10.1038/s41467-023-42342-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10611716/
  47. www.sciencedirect.com www.sciencedirect.com
    Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method
    1
    1. scibot 28 Oct 2023
      RRID:CVCL_Y019

      DOI: 10.1016/j.devcel.2023.09.008

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    sciencedirect.com/science/article/pii/S1534580723004951
  48. Sep 2023
  49. www.biorxiv.org www.biorxiv.org
    Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
    1
    1. scibot 30 Sep 2023
      RRID:CVCL_Y019

      DOI: 10.1101/2023.09.25.559255

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    biorxiv.org/content/10.1101/2023.09.25.559255v1
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for Coiled-coil-helix-coiled-coil-helix domain containing protein 10 (CHCHD10) for use in Western Blot, immunoprecipitation and immunofluorescence
    1
    1. scibot 29 Sep 2023
      CVCL_Y019

      DOI: 10.12688/f1000research.133479.2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10521100/
  51. Aug 2023
  52. www.science.org www.science.org
    Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12
    1
    1. scibot 27 Aug 2023
      RRID:CVCL_Y019

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    science.org/doi/10.1126/scisignal.adg0485
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for Profilin-1 for use in Western blot, immunoprecipitation and immunofluorescence
    1
    1. scibot 16 Aug 2023
      CVCL_Y019

      DOI: 10.12688/f1000research.132249.1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10415725/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for transmembrane protein 106B (TMEM106B) for use in Western blot, immunoprecipitation, and immunofluorescence
    1
    1. scibot 10 Aug 2023
      CVCL_Y019

      DOI: 10.12688/f1000research.131333.1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10403746/
  55. Jul 2023
  56. www.sciencedirect.com www.sciencedirect.com
    Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
    1
    1. scibot 15 Jul 2023
      RRID:CVCL_Y019

      DOI: 10.1016/j.celrep.2023.112807

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    sciencedirect.com/science/article/pii/S2211124723008185
  57. Jun 2023
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-preforming antibodies for Ubiquilin-2 for use in Western Blot, immunoprecipitation, and immunofluorescence
    1
    1. scibot 27 Jun 2023
      CVCL_Y019

      DOI: 10.12688/f1000research.131851.1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10285353/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for TDP-43 for use in Western Blot, immunoprecipitation and immunofluorescence
    1
    1. scibot 24 Jun 2023
      CVCL_Y019

      DOI: 10.12688/f1000research.131852.2

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  60. 52.53.155.43 52.53.155.43
    The identification of high-performing antibodies for Vacuolar protein sorting-associated protein 35 (hVPS35) for use in Western Blot, immunoprecipitation and immunofluorescence
    2
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    52.53.155.43/3699d5f980e0b6171344a18f720674e249948766/7d387731-c0ad-4a85-8ff4-5af49adcc5bc_133696_-_kathleen_southern-html.html
  61. 52.53.155.43 52.53.155.43
    The identification of high-performing antibodies for Coiled-coil-helix-coiled-coil-helix domain containing protein 10 (CHCHD10) for use in Western Blot, immunoprecipitation and immunofluorescence
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  62. 52.53.155.43 52.53.155.43
    The identification of high-performing antibodies for Midkine for use in Western blot and immunoprecipitation
    1
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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    APOE expression and secretion are modulated by mitochondrial dysfunction
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  64. May 2023
  65. 52.53.155.43 52.53.155.43
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  66. www.sciencedirect.com www.sciencedirect.com
    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
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  67. Apr 2023
  68. www.sciencedirect.com www.sciencedirect.com
    Salmonella invasion of a cell is self-limiting due to effector-driven activation of N-WASP
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  69. Mar 2023
  70. www.sciencedirect.com www.sciencedirect.com
    Phosphoantigen sensing combines TCR-dependent recognition of the BTN3A IgV domain and germline interaction with BTN2A1
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  71. Feb 2023
  72. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chikungunya virus entry and infectivity is primarily facilitated through cell line dependent attachment factors in mammalian and mosquito cells
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  74. Jan 2023
  75. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    ANALYSIS OF A PANEL OF TMEM16A CHLORIDE CHANNEL INHIBITORS REVEALS INDIRECT MECHANISMS INVOLVING ALTERATION OF CALCIUM SIGNALING
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  76. www.sciencedirect.com www.sciencedirect.com
    Rabies virus P protein binds to TBK1 and interferes with the formation of innate immunity-related liquid condensates
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  77. Nov 2022
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Mitochondrial RNA Granule Modulates Manganese-Dependent Cell Toxicity
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  79. Jul 2022
  80. www.sciencedirect.com www.sciencedirect.com
    Context-dependent regulation of ferroptosis sensitivity
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  81. Jun 2022
  82. www.sciencedirect.com www.sciencedirect.com
    Parkinson’s disease-risk protein TMEM175 is a proton-activated proton channel in lysosomes
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  83. Apr 2022
  84. www.sciencedirect.com www.sciencedirect.com
    Sulfur- and phosphorus-standardized metal quantification of biological specimens using inductively coupled plasma mass spectrometry
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  85. Dec 2021
  86. www.sciencedirect.com www.sciencedirect.com
    PPARα and PPARγ activation is associated with pleural mesothelioma invasion but therapeutic inhibition is ineffective
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  87. Nov 2021
  88. www.sciencedirect.com www.sciencedirect.com
    Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs
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  89. Aug 2021
  90. elifesciences.org elifesciences.org
    Quantitative live-cell imaging and computational modeling shed new light on endogenous WNT/CTNNB1 signaling dynamics
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  91. www.biorxiv.org www.biorxiv.org
    Scalable, FACS-Free Genome-Wide Phenotypic Screening
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  92. Jul 2021
  93. www.sciencedirect.com www.sciencedirect.com
    Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
    1
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  94. Jun 2021
  95. www.sciencedirect.com www.sciencedirect.com
    Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin
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  96. May 2021
  97. www.embopress.org www.embopress.org
    A method for benchmarking genetic screens reveals a predominant mitochondrial bias
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  98. Apr 2021
  99. www.sciencedirect.com www.sciencedirect.com
    NDUFS3 depletion permits complex I maturation and reveals TMEM126A/OPA7 as an assembly factor binding the ND4-module intermediate
    1
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    sciencedirect.com/science/article/pii/S2211124721003168
  100. Feb 2021
  101. www.sciencedirect.com www.sciencedirect.com
    Targeted degradation of the enhancer lysine acetyltransferases CBP and p300
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    sciencedirect.com/science/article/pii/S2451945620305134
  102. www.cell.com www.cell.com
    TMEM41B IS A PAN-FLAVIVIRUS HOST FACTOR
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    cell.com/cell/abstract/S0092-8674(20)31627-5
  103. Dec 2020
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
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  105. Oct 2020
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    POMK regulates dystroglycan function via LARGE1-mediated elongation of matriglycan
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  107. Sep 2020
  108. www.nature.com www.nature.com
    Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9–Cas12a platform
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  109. elifesciences.org elifesciences.org
    p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POLθ pathways
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  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Skd3 (human ClpB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations
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  111. Jan 2020
  112. www.nature.com www.nature.com
    High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting
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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  114. www.sciencedirect.com www.sciencedirect.com
    Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
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  115. Nov 2018
  116. www.sciencedirect.com www.sciencedirect.com
    Functional Domains of NEAT1 Architectural lncRNA Induce Paraspeckle Assembly through Phase Separation
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  117. www.sciencedirect.com www.sciencedirect.com
    Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread
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    sciencedirect.com/science/article/pii/S1931312817303906
  118. www.sciencedirect.com www.sciencedirect.com
    MLKL Requires the Inositol Phosphate Code to Execute Necroptosis
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  120. Nov 2017
  121. www.eneuro.org www.eneuro.org
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of protein O-mannose kinase reveals a unique active site architecture
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    ncbi.nlm.nih.gov/pmc/articles/PMC5142810/