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  1. Mar 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    7,7”-dimethoxyagastisflavone induced MYCN/MYBL2-dependent apoptosis and metabolism reprogramming in Sonic Hedgehog medulloblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12997686/
  3. www.sciencedirect.com www.sciencedirect.com
    Cancer cell-derived sialylated IgG interacting with Siglec-7/9/10 is a potential immunotherapeutic target in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2666379126000777
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Selective inhibition of ALDH1A3 impedes breast cancer growth and metastasis by blocking ALDH1A3-driven transcriptional programs
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    pmc.ncbi.nlm.nih.gov/articles/PMC12962171/
  5. Feb 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The molecular and functional landscape of resistance to FOLFIRI chemotherapy in metastatic colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12877753/
  7. Jan 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor-associated macrophages educated by IGSF9 exhibit a senescence-associated secretory phenotype to promote tumor immune escape
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    pmc.ncbi.nlm.nih.gov/articles/PMC12815053/
  9. Dec 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLC6A14 Drives Mitochondrial Fusion and Oxidative Phosphorylation to Promote Cancer Stemness and Early‐Onset of Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12677700/
  11. Nov 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microtubule architecture connects AMOT stability to YAP/TAZ mechanotransduction and Hippo signalling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12527920/
  13. www.nature.com www.nature.com
    Oncostatin M induces epigenetic reprogramming in renal cell carcinoma-associated endothelial cells
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    nature.com/articles/s42003-025-08907-x
  14. Sep 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PPAR-δ Orchestrates a Pro-metastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402788/
  16. Jul 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CAMKKβ supports growth and viability of epithelial ovarian cancer in vitro and in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC12271461/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214879/
  19. Apr 2025
  20. 52.53.155.43 52.53.155.43
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  21. Jan 2025
  22. www.mdpi.com www.mdpi.com
    Doxycycline Restores Gemcitabine Sensitivity in Preclinical Models of Multidrug-Resistant Intrahepatic Cholangiocarcinoma
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    mdpi.com/2072-6694/17/1/132
  23. Dec 2024
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pathogenic mitochondrial DNA variants are associated with response to anti-VEGF therapy in ovarian cancer PDX models
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    pmc.ncbi.nlm.nih.gov/articles/PMC11657443/
  25. Oct 2024
  26. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ERK1/2 mitogen-activated protein kinase dimerization is essential for the regulation of cell motility
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13732
  27. Aug 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FEBS Press
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    ncbi.nlm.nih.gov/pmc/articles/PMC10323897/
  29. May 2024
  30. www.sciencedirect.com www.sciencedirect.com
    A computational pipeline for identifying gene targets and signalling pathways in cancer cells to improve lymphocyte infiltration and immune checkpoint therapy efficacy
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    sciencedirect.com/science/article/pii/S2352396424002020
  31. Apr 2024
  32. www.sciencedirect.com www.sciencedirect.com
    Endothelial progenitor cells control remodeling of uterine spiral arteries for the establishment of utero-placental circulation
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    sciencedirect.com/science/article/pii/S153458072400234X
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PARP inhibitors suppress tumours via centrosome error-induced senescence independent of DNA damage response
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    ncbi.nlm.nih.gov/pmc/articles/PMC11052917/
  34. Dec 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Dissecting embryonic and extraembryonic lineage crosstalk with stem cell co-culture
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    sciencedirect.com/science/article/pii/S0092867423012254
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional maturation of human iPSC-derived pyramidal neurons in vivo is dependent on proximity with the host tissue
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    ncbi.nlm.nih.gov/pmc/articles/PMC10708947/
  37. Oct 2023
  38. aacrjournals.org aacrjournals.org
    Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.
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    aacrjournals.org/cancerrescommun/article/3/10/2030/729478/Piperacetazine-Directly-Binds-to-the-PAX3-FOXO1
  39. Sep 2023
  40. www.sciencedirect.com www.sciencedirect.com
    A NRF2 inhibitor selectively sensitizes KEAP1 mutant tumor cells to cisplatin and gefitinib by restoring NRF2-inhibitory function of KEAP1 mutants
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    sciencedirect.com/science/article/pii/S2211124723011154
  41. Jun 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Efficacy of the Antibody–Drug Conjugate CLDN6–23-ADC for the Treatment of CLDN6-Positive Solid Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10233360/
  43. Apr 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FEBS Press
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    ncbi.nlm.nih.gov/pmc/articles/PMC10323897/
  45. Jan 2023
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapy-induced senescence enhances the efficacy of HER2-targeted antibody-drug conjugates in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9755966/
  47. Dec 2022
  48. 52.53.155.43 52.53.155.43
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  49. Sep 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of RING and PHD Domains of TRIM28 Evokes Differentiation in Human iPSCs
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    ncbi.nlm.nih.gov/pmc/articles/PMC8394524/
  51. Aug 2021
  52. elifesciences.org elifesciences.org
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    elifesciences.org/articles/30224
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse
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    pmc.ncbi.nlm.nih.gov/articles/PMC6760242/
  54. Jul 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas
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    sciencedirect.com/science/article/pii/S2211124719314056
  56. www.sciencedirect.com www.sciencedirect.com
    Radiologic and Genomic Evolution of Individual Metastases during HER2 Blockade in Colorectal Cancer
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    sciencedirect.com/science/article/pii/S1535610818302617
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC5773178/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6414201/
  59. May 2021
  60. www.nature.com www.nature.com
    Cancer of unknown primary stem-like cells model multi-organ metastasis and unveil liability to MEK inhibition
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    nature.com/articles/s41467-021-22643-w
  61. www.sciencedirect.com www.sciencedirect.com
    Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification
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    sciencedirect.com/science/article/pii/S1934590920305415
  62. Feb 2021
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC7501074/
  64. Sep 2020
  65. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Oxygen-enhanced optoacoustic tomography reveals the effectiveness of targeting heme and oxidative phosphorylation at normalizing tumor vascular oxygenation
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    cancerres.aacrjournals.org/content/80/17/3542
  66. www.sciencedirect.com www.sciencedirect.com
    Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
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    sciencedirect.com/science/article/pii/S1934590920300540
  67. Jan 2020
  68. www.sciencedirect.com www.sciencedirect.com
    Acquisition of a Unique Mesenchymal Precursor-like Blastema State Underlies Successful Adult Mammalian Digit Tip Regeneration
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    sciencedirect.com/science/article/pii/S1534580719310251
  69. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Elevated Heme Synthesis and Uptake Underpin Intensified Oxidative Metabolism and Tumorigenic Functions in Non–Small Cell Lung Cancer Cells
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    cancerres.aacrjournals.org/content/79/10/2511
  70. Nov 2018
  71. www.sciencedirect.com www.sciencedirect.com
    MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation
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    sciencedirect.com/science/article/pii/S1535610818302691
  72. Nov 2017
  73. www.sciencedirect.com www.sciencedirect.com
    Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming
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    sciencedirect.com/science/article/pii/S1934590917303387