52 Matching Annotations
  1. Jul 2026
  2. aacrjournals.org aacrjournals.org
    AKT3-Driven Epithelial-Mesenchymal Plasticity Governs Ovarian Metastasis in Colorectal Cancer via Tumor Microenvironment Remodeling
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    aacrjournals.org/cancerres/article/86/10/2537/784901/AKT3-Driven-Epithelial-Mesenchymal-Plasticity
  3. May 2026
  4. www.sciencedirect.com www.sciencedirect.com
    Giredestrant immobilizes the estrogen receptor to exert potent antitumor efficacy against ER-active breast cancers
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    sciencedirect.com/science/article/pii/S2451945626001431
  5. www.biorxiv.org www.biorxiv.org
    SIMO – Single Section Integrative Multi-Omics – spatial mapping of metabolites and lipids combined with region-specific proteomics in a single tissue slice
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    biorxiv.org/content/10.64898/2026.04.17.719206v1
  6. Apr 2026
  7. 54.241.53.176 54.241.53.176
    Supplementary file-html.html
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    54.241.53.176/4d06b1922c474219b22e5a7827bebd122dca3f2f/Supplementary file-html.html
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
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    pmc.ncbi.nlm.nih.gov/articles/PMC13060634/
  9. aacrjournals.org aacrjournals.org
    A Novel Anti-CD47 Antibody TJH2201: Efficacious Tumor Suppression with Reduced RBC Toxicity via a SIRPα-Independent Mechanism
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    aacrjournals.org/mct/article/25/1/21/771288/A-Novel-Anti-CD47-Antibody-TJH2201-Efficacious
  10. Mar 2026
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    7,7”-dimethoxyagastisflavone induced MYCN/MYBL2-dependent apoptosis and metabolism reprogramming in Sonic Hedgehog medulloblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12997686/
  12. www.sciencedirect.com www.sciencedirect.com
    Cancer cell-derived sialylated IgG interacting with Siglec-7/9/10 is a potential immunotherapeutic target in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2666379126000777
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Selective inhibition of ALDH1A3 impedes breast cancer growth and metastasis by blocking ALDH1A3-driven transcriptional programs
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    pmc.ncbi.nlm.nih.gov/articles/PMC12962171/
  14. Feb 2026
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The molecular and functional landscape of resistance to FOLFIRI chemotherapy in metastatic colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12877753/
  16. Jan 2026
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor-associated macrophages educated by IGSF9 exhibit a senescence-associated secretory phenotype to promote tumor immune escape
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    pmc.ncbi.nlm.nih.gov/articles/PMC12815053/
  18. Dec 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLC6A14 Drives Mitochondrial Fusion and Oxidative Phosphorylation to Promote Cancer Stemness and Early‐Onset of Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12677700/
  20. Nov 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microtubule architecture connects AMOT stability to YAP/TAZ mechanotransduction and Hippo signalling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12527920/
  22. www.nature.com www.nature.com
    Oncostatin M induces epigenetic reprogramming in renal cell carcinoma-associated endothelial cells
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    nature.com/articles/s42003-025-08907-x
  23. Sep 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PPAR-δ Orchestrates a Pro-metastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402788/
  25. Jul 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CAMKKβ supports growth and viability of epithelial ovarian cancer in vitro and in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC12271461/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214879/
  28. Apr 2025
  29. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/73f4a278983fd3a9b93fed6443158024ffc69ddc/PDF-html.html
  30. Jan 2025
  31. www.mdpi.com www.mdpi.com
    Doxycycline Restores Gemcitabine Sensitivity in Preclinical Models of Multidrug-Resistant Intrahepatic Cholangiocarcinoma
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    mdpi.com/2072-6694/17/1/132
  32. Dec 2024
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pathogenic mitochondrial DNA variants are associated with response to anti-VEGF therapy in ovarian cancer PDX models
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    pmc.ncbi.nlm.nih.gov/articles/PMC11657443/
  34. Oct 2024
  35. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ERK1/2 mitogen-activated protein kinase dimerization is essential for the regulation of cell motility
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13732
  36. Aug 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FEBS Press
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    ncbi.nlm.nih.gov/pmc/articles/PMC10323897/
  38. May 2024
  39. www.sciencedirect.com www.sciencedirect.com
    A computational pipeline for identifying gene targets and signalling pathways in cancer cells to improve lymphocyte infiltration and immune checkpoint therapy efficacy
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    sciencedirect.com/science/article/pii/S2352396424002020
  40. Apr 2024
  41. www.sciencedirect.com www.sciencedirect.com
    Endothelial progenitor cells control remodeling of uterine spiral arteries for the establishment of utero-placental circulation
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    sciencedirect.com/science/article/pii/S153458072400234X
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PARP inhibitors suppress tumours via centrosome error-induced senescence independent of DNA damage response
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    ncbi.nlm.nih.gov/pmc/articles/PMC11052917/
  43. Dec 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Dissecting embryonic and extraembryonic lineage crosstalk with stem cell co-culture
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    sciencedirect.com/science/article/pii/S0092867423012254
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional maturation of human iPSC-derived pyramidal neurons in vivo is dependent on proximity with the host tissue
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    ncbi.nlm.nih.gov/pmc/articles/PMC10708947/
  46. Oct 2023
  47. aacrjournals.org aacrjournals.org
    Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.
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    aacrjournals.org/cancerrescommun/article/3/10/2030/729478/Piperacetazine-Directly-Binds-to-the-PAX3-FOXO1
  48. Sep 2023
  49. www.sciencedirect.com www.sciencedirect.com
    A NRF2 inhibitor selectively sensitizes KEAP1 mutant tumor cells to cisplatin and gefitinib by restoring NRF2-inhibitory function of KEAP1 mutants
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    sciencedirect.com/science/article/pii/S2211124723011154
  50. Jun 2023
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Efficacy of the Antibody–Drug Conjugate CLDN6–23-ADC for the Treatment of CLDN6-Positive Solid Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10233360/
  52. Apr 2023
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FEBS Press
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    ncbi.nlm.nih.gov/pmc/articles/PMC10323897/
  54. Jan 2023
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapy-induced senescence enhances the efficacy of HER2-targeted antibody-drug conjugates in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9755966/
  56. Dec 2022
  57. 52.53.155.43 52.53.155.43
    can-22-0787-html.html
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    52.53.155.43/fc7b32e58251b729fd8b8d78c9ec2c38de3723af/can-22-0787-html.html
  58. Sep 2021
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of RING and PHD Domains of TRIM28 Evokes Differentiation in Human iPSCs
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    ncbi.nlm.nih.gov/pmc/articles/PMC8394524/
  60. Aug 2021
  61. elifesciences.org elifesciences.org
    Untitled document
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    elifesciences.org/articles/30224
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse
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    pmc.ncbi.nlm.nih.gov/articles/PMC6760242/
  63. Jul 2021
  64. www.sciencedirect.com www.sciencedirect.com
    Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas
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    sciencedirect.com/science/article/pii/S2211124719314056
  65. www.sciencedirect.com www.sciencedirect.com
    Radiologic and Genomic Evolution of Individual Metastases during HER2 Blockade in Colorectal Cancer
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    sciencedirect.com/science/article/pii/S1535610818302617
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC5773178/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6414201/
  68. May 2021
  69. www.nature.com www.nature.com
    Cancer of unknown primary stem-like cells model multi-organ metastasis and unveil liability to MEK inhibition
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    nature.com/articles/s41467-021-22643-w
  70. www.sciencedirect.com www.sciencedirect.com
    Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification
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    sciencedirect.com/science/article/pii/S1934590920305415
  71. Feb 2021
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC7501074/
  73. Sep 2020
  74. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Oxygen-enhanced optoacoustic tomography reveals the effectiveness of targeting heme and oxidative phosphorylation at normalizing tumor vascular oxygenation
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    cancerres.aacrjournals.org/content/80/17/3542
  75. www.sciencedirect.com www.sciencedirect.com
    Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
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    sciencedirect.com/science/article/pii/S1934590920300540
  76. Jan 2020
  77. www.sciencedirect.com www.sciencedirect.com
    Acquisition of a Unique Mesenchymal Precursor-like Blastema State Underlies Successful Adult Mammalian Digit Tip Regeneration
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    sciencedirect.com/science/article/pii/S1534580719310251
  78. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Elevated Heme Synthesis and Uptake Underpin Intensified Oxidative Metabolism and Tumorigenic Functions in Non–Small Cell Lung Cancer Cells
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    cancerres.aacrjournals.org/content/79/10/2511
  79. Nov 2018
  80. www.sciencedirect.com www.sciencedirect.com
    MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation
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    sciencedirect.com/science/article/pii/S1535610818302691
  81. Nov 2017
  82. www.sciencedirect.com www.sciencedirect.com
    Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming
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    sciencedirect.com/science/article/pii/S1934590917303387