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  1. Last 7 days
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    Potency and safety of novel [225Ac]Ac-labeled pertuzumab-PEGylated emtansine drug conjugate against HER2-positive breast cancer
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    nature.com/articles/s41416-026-03393-2
  3. Mar 2026
  4. www.sciencedirect.com www.sciencedirect.com
    Expanded applications of bioluminescence microscopy with phasor analysis
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    sciencedirect.com/science/article/pii/S2667237526000445
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    A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy
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    sciencedirect.com/science/article/pii/S0092867426002692
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microglia Display Heterogeneous Initial Responses to Disseminated Tumor Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012254/
  7. Feb 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    [225Ac]Ac-labeled matuzumab is an effective radioimmunotherapeutic against EGFR-positive triple negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12892558/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Colorectal cancer-derived osteopontin rewires macrophages into a pro-metastatic M2 state via the PI3K/AKT/CSF1-CSF1R axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12894849/
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    Pharmacokinetic-pharmacodynamic-efficacy modeling of the MDM2 inhibitor brigimadlin in glioblastoma patient-derived xenografts
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    pmc.ncbi.nlm.nih.gov/articles/PMC12883205/
  11. Jan 2026
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    A Jagged1-regulated hybrid-EMT state identifies pancreatic cancer stem cells
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  13. Dec 2025
  14. 54.241.53.176 54.241.53.176
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    Nε-Carboxymethyl-Lysine Drives Centrosome Amplification and Hepatocarcinogenesis via Pathological Dysregulation of the PLK1-CEP20-CCDC116 Axis
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    pubs.acs.org/doi/10.1021/acs.jafc.5c10762
  16. Oct 2025
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    Development of retinoid nuclear receptor pathway antagonists through targeting aldehyde dehydrogenase 1A3
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    sciencedirect.com/science/article/pii/S2589004225019364
  18. Sep 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pre-clinical Modeling of Navtemadlin Pharmacokinetics, Pharmacodynamics, and Efficacy in IDH-wildtype Glioblastoma
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  20. Jul 2025
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    Tumor-specific antigen delivery for T-cell therapy via a pH-sensitive peptide conjugate
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    pmc.ncbi.nlm.nih.gov/articles/PMC11695185/
  22. Jun 2025
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    BRAF/MEK inhibition induces cell state transitions boosting immune checkpoint sensitivity in BRAFV600E-mutant glioma
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    Inhibition of NAD-GPx4 axis and MEK triggers ferroptosis to suppress pancreatic ductal adenocarcinoma
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  26. May 2025
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  28. Feb 2025
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SMAD4 and KRAS Status Shape Cancer Cell-Stromal Crosstalk and Therapeutic Response in Pancreatic Cancer
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  30. Jan 2025
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  32. Dec 2024
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    Development and evaluation of a single domain antibody targeting folate receptor alpha for radioligand therapy
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  34. Nov 2024
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  36. Sep 2024
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    Distinct tumor architectures and microenvironments for the initiation of breast cancer metastasis in the brain
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    TGF-β and RAS jointly unmask primed enhancers to drive metastasis
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  39. May 2024
  40. www.biorxiv.org www.biorxiv.org
    SMAD4 and KRAS status shape malignant-stromal crosstalk in pancreatic cancer
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    biorxiv.org/content/10.1101/2024.04.28.591518v1
  41. Mar 2024
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors
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  43. Feb 2024
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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatial Immunoprofiling of Adenoid Cystic Carcinoma Reveals B7-H4 Is a Therapeutic Target for Aggressive Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10526680/
  46. Apr 2023
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
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  48. Mar 2023
  49. www.thelancet.com www.thelancet.com
    Metformin and simvastatin exert additive antitumour effects in glioblastoma via senescence-state: clinical and translational evidence
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00049-X/abstract
  50. aacrjournals.org aacrjournals.org
    Safety and efficacy of intraventricular immunovirotherapy with oncolytic HSV-1 for CNS cancers
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    aacrjournals.org/clincancerres/article/28/24/5419/711437/Safety-and-Efficacy-of-Intraventricular
  51. Dec 2022
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  53. Sep 2022
  54. www.sciencedirect.com www.sciencedirect.com
    A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-β2 signaling
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    sciencedirect.com/science/article/pii/S2211124722011901
  55. May 2022
  56. aacrjournals.org aacrjournals.org
    Secretion of interleukin-1 by dedifferentiated melanoma cells inhibits JAK1-STAT3-driven actomyosin contractility of lymph node fibroblastic reticular cells
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    aacrjournals.org/cancerres/article/82/9/1774/694699/Secretion-of-IL1-by-Dedifferentiated-Melanoma
  57. Nov 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug
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    sciencedirect.com/science/article/pii/S2211124721014340
  59. Jul 2021
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    ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors
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    sciencedirect.com/science/article/pii/S2666379121001993
  61. Apr 2021
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    YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis
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    sciencedirect.com/science/article/pii/S1535610820304980
  63. Nov 2017
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    Complement Component 3 Adapts the Cerebrospinal Fluid for Leptomeningeal Metastasis
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    sciencedirect.com/science/article/pii/S0092867417302404
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    Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature
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    sciencedirect.com/science/article/pii/S1535610817301010