Hypothesis

17 Matching Annotations

Jun 2026
www.sciencedirect.com www.sciencedirect.com

Temporal control of sgRNA library activation unlocks large-scale in vivo CRISPR screens

1
1. scibot 03 Jun 2026
  
  in Public
  
  RRID:IMSR_CRL:572
  
  DOI: 10.1016/j.crmeth.2026.101470
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572
Visit annotations in context

Tags

RRID:IMSR_CRL:572

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2667237526001700
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

KSR1 mediates small-cell lung carcinoma tumor initiation and cisplatin resistance

1
1. scibot 06 Dec 2025
  
  in Public
  
  CRL:572
  
  DOI: 10.1158/1541-7786.MCR-24-0652
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572
Visit annotations in context

Tags

RRID:IMSR_CRL:572

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12133430/
Nov 2025
www.sciencedirect.com www.sciencedirect.com

Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells

1
1. scibot 13 Nov 2025
  
  in Public
  
  Charles Rivers LaboratoriesStrain Code#572
  
  DOI: 10.1016/j.xcrm.2025.102446
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572
Visit annotations in context

Tags

RRID:IMSR_CRL:572

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379125005191
Aug 2025
jitc.bmj.com jitc.bmj.com

An affinity-modulated T cell engager targeting Claudin 18.2 shows potent anti-tumor activity with limited cytokine release

1
1. scibot 07 Aug 2025
  
  in Public
  
  RRID:IMSR_CRL:572
  
  DOI: 10.1136/jitc-2025-011857
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572
Visit annotations in context

Tags

RRID:IMSR_CRL:572

Annotators

scibot

URL

jitc.bmj.com/content/13/8/e011857
May 2025
www.sciencedirect.com www.sciencedirect.com

Generation of T cell responses against broad KRAS hotspot neoantigens for cell therapy or TCR discovery

1
1. scibot 17 May 2025
  
  in Public
  
  RRID:IMSR_CRL:572
  
  DOI: 10.1016/j.crmeth.2025.101049
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572
Visit annotations in context

Tags

RRID:IMSR_CRL:572

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2667237525000852
52.53.155.43 52.53.155.43

1-s2.0-S2589004225008454-main-html.html

1
1. scibot 16 May 2025
  
  in Public
  
  Charles River Laboratories Strain Code 572
  
  DOI: 10.1016/j.isci.2025.112584
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572
Visit annotations in context

Tags

RRID:IMSR_CRL:572

Annotators

scibot

URL

52.53.155.43/2f59eea255f6dfa2798e1e0fcb3d7e10d3ba6bc8/1-s2.0-S2589004225008454-main-html.html
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Preclinical Characterization of ARX517, a Site-Specific Stable PSMA-Targeted Antibody–Drug Conjugate for the Treatment of Metastatic Castration-Resistant Prostate Cancer

1
1. scibot 11 Dec 2024
  
  in Public
  
  RRID:IMSR_CRL:572
  
  DOI: 10.1158/1535-7163.MCT-23-0927
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572
Visit annotations in context

Tags

RRID:IMSR_CRL:572

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11612621/
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy

1
1. scibot 17 Sep 2024
  
  in Public
  
  Strain code: 572NCG
  
  DOI: 10.1016/j.cell.2024.08.029
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572
Visit annotations in context

Tags

RRID:IMSR_CRL:572

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867424009565
Apr 2024
www.biorxiv.org www.biorxiv.org

PVRL2 Suppresses Anti-tumor Immunity Through PVRIG- and TIGIT-Independent Pathways

1
1. scibot 02 Apr 2024
  
  in Public
  
  572
  
  DOI: 10.1101/2024.01.26.577132
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572
Visit annotations in context

Tags

RRID:IMSR_CRL:572

Annotators

scibot

URL

biorxiv.org/content/10.1101/2024.01.26.577132v1
Sep 2023
www.nature.com www.nature.com

A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer

1
1. scibot 08 Sep 2023
  
  in Public
  
  RRID:IMSR_CRL:572
  
  DOI: 10.1038/s41467-023-40798-6
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572
Visit annotations in context

Tags

RRID:IMSR_CRL:572

Annotators

scibot

URL

nature.com/articles/s41467-023-40798-6
Sep 2022
www.sciencedirect.com www.sciencedirect.com

A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-β2 signaling

1
1. scibot 22 Sep 2022
  
  in Public
  
  NCG mice (NOD-Prkdcem26Cd52Il2rgem26Cd22/NjuCrl)
  
  DOI: 10.1016/j.celrep.2022.111358
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572
Visit annotations in context

Tags

RRID:IMSR_CRL:572

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722011901
Aug 2022
www.sciencedirect.com www.sciencedirect.com

A tubulin binding molecule drives differentiation of acute myeloid leukemia cells

1
1. scibot 17 Aug 2022
  
  in Public
  
  RRID:IMSR_CRL:572
  
  DOI: 10.1016/j.isci.2022.104787
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572
Visit annotations in context

Tags

RRID:IMSR_CRL:572

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004222010598
Jan 2022
www.sciencedirect.com www.sciencedirect.com

Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells

1
1. scibot 16 Jan 2022
  
  in Public
  
  Charles River LaboratoriesCat#572
  
  DOI: 10.1016/j.celrep.2021.110236
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572
Visit annotations in context

Tags

RRID:IMSR_CRL:572

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721017459
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Triple targeting of breast tumors driven by hormonal receptors and HER2

1
1. scibot 11 Jan 2022
  
  in Public
  
  RRID:IMSR_CRL:572
  
  DOI: 10.1158/1535-7163.MCT-21-0098
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572
Visit annotations in context

Tags

RRID:IMSR_CRL:572

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8742793/
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hormonal regulation of Semaphorin 7a in ER+ breast cancer drives therapeutic resistance

1
1. scibot 03 Jul 2021
  
  in Public
  
  RRID:IMSR_CRL:572
  
  DOI: 10.1158/0008-5472.CAN-20-1601
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572
Visit annotations in context

Tags

RRID:IMSR_CRL:572

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7878309/
May 2021
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

Targeting DNA damage repair functions of two histone deacetylases, HDAC8 and SIRT6, sensitizes acute myeloid leukemia to NAMPT inhibition

1
1. scibot 12 May 2021
  
  in Public
  
  RRID:IMSR_CRL
  
  DOI: 10.1158/1078-0432.CCR-20-3724
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  Curator comments: NOD-Prkdcem26Cd52Il2rgem26Cd22/NjuCrl Mus musculus IMSR Cat# CRL:572
  
  What is this?
  
  RRIDCUR:SyntaxError RRID:IMSR_CRL:572 RRIDCUR:Unresolved
Visit annotations in context

Tags

RRID:IMSR_CRL:572

RRIDCUR:Unresolved

RRIDCUR:SyntaxError

Annotators

scibot

URL

clincancerres.aacrjournals.org/content/27/8/2352
Jan 2020
www.cell.com www.cell.com

Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_CRL:572
  
  DOI: 10.1016/j.cell.2019.02.016
  
  Resource: (IMSR Cat# CRL_572,RRID:IMSR_CRL:572)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_CRL:572
  
  What is this?
  
  RRID:IMSR_CRL:572 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:IMSR_CRL:572

RRIDCUR:Validated

Annotators

scibot

URL

cell.com/cell/fulltext/S0092-8674(19)30165-5