Hypothesis

23 Matching Annotations

Last 7 days
www.sciencedirect.com www.sciencedirect.com

An antibody-PROTAC conjugate targets BRD4/c-Myc/PD-L1 to enhance immunotherapy efficacy in triple-negative breast cancer

1
1. scibot 31 Jul 2026
  
  in Public
  
  RRID:IMSR_GPT:N000020
  
  DOI: 10.1016/j.xcrm.2026.102948
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
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  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

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scibot

URL

sciencedirect.com/science/article/pii/S2666379126003654
Apr 2026
www.sciencedirect.com www.sciencedirect.com

Palmitic acid reprograms neutrophils to compromise vascular integrity and promote breast cancer lung metastasis

1
1. scibot 25 Apr 2026
  
  in Public
  
  RRID:IMSR_GPT:N000020
  
  DOI: 10.1016/j.immuni.2026.03.026
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

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scibot

URL

sciencedirect.com/science/article/pii/S1074761326001378
www.sciencedirect.com www.sciencedirect.com

Modular double-stranded DNA recognition defines specificity of the exonuclease TREX1 in cGAS-STING control

1
1. scibot 25 Apr 2026
  
  in Public
  
  RRID:IMSR_GPT:N000020
  
  DOI: 10.1016/j.immuni.2026.03.025
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

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scibot

URL

sciencedirect.com/science/article/pii/S1074761326001366
54.241.53.176 54.241.53.176

1-s2.0-S2589004226009533-main-html.html

1
1. scibot 09 Apr 2026
  
  in Public
  
  Gem Pharmatech Cat#N000020
  
  DOI: 10.1016/j.isci.2026.115578
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

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scibot

URL

54.241.53.176/aa3e0f41f285132e3e980831995e53fa5d34affa/1-s2.0-S2589004226009533-main-html.html
Mar 2026
www.sciencedirect.com www.sciencedirect.com

AK5 suppresses breast cancer progression and modulates anti-PD-L1 efficacy via the miR-182-5p/PD-L1 axis

1
1. scibot 24 Mar 2026
  
  in Public
  
  GempharmatechN000020
  
  DOI: 10.1016/j.isci.2026.115260
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

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scibot

URL

sciencedirect.com/science/article/pii/S2589004226006358
www.sciencedirect.com www.sciencedirect.com

HE4 drives PD-L1 expression in myeloid cells via IFN-γR-JAK-STAT3 signaling to promote tumor immune evasion

1
1. scibot 20 Mar 2026
  
  in Public
  
  GemPharmatechN000020
  
  DOI: 10.1016/j.xcrm.2026.102691
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

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scibot

URL

sciencedirect.com/science/article/pii/S2666379126001084
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting OxLDL-mediated CD36 + CAF reprogramming potentiates PD-1 immunotherapy in osteosarcoma

1
1. scibot 28 Jan 2026
  
  in Public
  
  RRID:IMSR_GPT
  
  DOI: 10.1186/s12943-025-02516-2
  
  Resource: None
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020 RRIDCUR:Unresolved
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RRID:IMSR_GPT:N000020

RRIDCUR:Unresolved

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12829093/
www.sciencedirect.com www.sciencedirect.com

Pregnenolone promotes immune evasion through blocking endogenous retrovirus expression

1
1. scibot 27 Jan 2026
  
  in Public
  
  GemPharmatechCat# N000020
  
  DOI: 10.1016/j.cmet.2025.12.020
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

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scibot

URL

sciencedirect.com/science/article/pii/S1550413125005844
Oct 2025
www.sciencedirect.com www.sciencedirect.com

Structure and function of a pair of non-competing monoclonal antibodies against Langya henipavirus attachment glycoprotein

1
1. scibot 15 Oct 2025
  
  in Public
  
  Gempharmatech-GDCat# N000020
  
  DOI: 10.1016/j.celrep.2025.116407
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

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scibot

URL

sciencedirect.com/science/article/pii/S2211124725011787
Jun 2025
www.sciencedirect.com www.sciencedirect.com

Arachidonic acid triggers spermidine synthase secretion from primary tumor to induce skeletal muscle weakness upon irradiation

1
1. scibot 21 Jun 2025
  
  in Public
  
  GemPharmatech Co., LtdBALB/cJGpt, Strain NO. N000020
  
  DOI: 10.1016/j.cmet.2025.05.013
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

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scibot

URL

sciencedirect.com/science/article/pii/S1550413125002694
Apr 2025
www.sciencedirect.com www.sciencedirect.com

The low-dose CHK1 inhibitor prexasertib triggers VDAC1 dephosphorylation to activate mtDNA-STING signaling and synergize immunotherapy

1
1. scibot 19 Apr 2025
  
  in Public
  
  GemPharmatech, Nanjing, ChinaNO. N000020
  
  DOI: 10.1016/j.celrep.2025.115605
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

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scibot

URL

sciencedirect.com/science/article/pii/S2211124725003766
www.sciencedirect.com www.sciencedirect.com

Protocol for renal subcapsular islet transplantation in diabetic mice to induce long-term immune tolerance

1
1. scibot 08 Apr 2025
  
  in Public
  
  GemPharmatech Co., LtdStrain#N000020
  
  DOI: 10.1016/j.xpro.2025.103729
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

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scibot

URL

sciencedirect.com/science/article/pii/S2666166725001352
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Targeting tumor monocyte-intrinsic PD-L1 by rewiring STING signaling and enhancing STING agonist therapy

1
1. scibot 11 Mar 2025
  
  in Public
  
  GemPharmatechStrain NO.N000020
  
  DOI: 10.1016/j.ccell.2025.02.014
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610825000662
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Early fusion intermediate of ACE2-using coronavirus spike acting as an antiviral target

1
1. scibot 31 Jan 2025
  
  in Public
  
  RRID:IMSR_GPT:N000020
  
  DOI: 10.1016/j.cell.2025.01.012
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

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scibot

URL

sciencedirect.com/science/article/pii/S0092867425000418
Dec 2024
www.cell.com www.cell.com

Disrupted methionine cycle triggers muscle atrophy in cancer cachexia through epigenetic regulation of REDD1

1
1. scibot 29 Dec 2024
  
  in Public
  
  N000020
  
  DOI: 10.1016/0140-6701(96)90942-x
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

Annotators

scibot

URL

cell.com/cell-metabolism/fulltext/S1550-4131(24)00413-3
Nov 2024
www.sciencedirect.com www.sciencedirect.com

DHDH-mediated D-xylose metabolism induces immune evasion in triple-negative breast cancer

1
1. scibot 11 Nov 2024
  
  in Public
  
  Strain NO.N000020
  
  DOI: 10.1016/j.medj.2024.10.012
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666634024004100
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer

1
1. scibot 25 Sep 2024
  
  in Public
  
  Cat#: N000020
  
  DOI: 10.1016/j.ccell.2024.08.019
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610824003180
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Tumor-intrinsic P2RY6 drives immunosuppression by enhancing PGE2 production

1
1. scibot 12 Jul 2024
  
  in Public
  
  RRID:IMSR_GPT:N000020
  
  DOI: 10.1016/j.celrep.2024.114469
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724007988
www.cell.com www.cell.com

Engineering an energy-dissipating hybrid tissue in vivo for obesity treatment

1
1. scibot 12 Jul 2024
  
  in Public
  
  RRID:IMSR_GPT:N000020
  
  DOI: 10.1016/j.celrep.2024.114425
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

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scibot

URL

cell.com/cell-reports/fulltext/S2211-1247(24)00754-X
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma

2
1. scibot 17 May 2024
  
  in Public
  
  RRID:IMSR_GPT:N000020
  
  DOI: 10.1158/0008-5472.CAN-23-2521
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRID:IMSR_GPT:N000020
2. scibot 17 May 2024
  
  in Public
  
  RRID:IMSR_GPT
  
  DOI: 10.1158/0008-5472.CAN-23-2521
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

RRIDCUR:Unresolved

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11094425/
Apr 2024
aacrjournals.org aacrjournals.org

Osteosarcoma cells secrete CXCL14 that activates integrin α11β1 on fibroblasts to form a lung metastatic niche

1
1. scibot 19 Apr 2024
  
  in Public
  
  RRID:IMSR_GPT
  
  DOI: 10.1158/0008-5472.CAN-23-1307
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

RRIDCUR:Unresolved

Annotators

scibot

URL

aacrjournals.org/cancerres/article/84/7/994/742036/Osteosarcoma-Cells-Secrete-CXCL14-That-Activates
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Creatine promotes cancer metastasis through activation of Smad2/3

1
1. scibot 06 Apr 2021
  
  in Public
  
  N000020
  
  DOI: 10.1016/j.cmet.2021.03.009
  
  Resource: (IMSR Cat# GPT_N000020,RRID:IMSR_GPT:N000020)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_GPT:N000020
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_GPT:N000020
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RRID:IMSR_GPT:N000020

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413121001169