56 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Krüppel-like factor 10 protects against metabolic dysfunction-associated steatohepatitis by regulating HNF4α-mediated metabolic pathways
    1
    1. scibot 10 Apr 2024
      000632

      DOI: 10.1016/j.metabol.2024.155909

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    sciencedirect.com/science/article/pii/S0026049524001355
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T cells with increased responsiveness cause obesity in mice without diet intervention
    1
    1. scibot 03 Apr 2024
      Jackson Laboratory#000632

      DOI: 10.1016/j.isci.2024.109471

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    ncbi.nlm.nih.gov/pmc/articles/PMC10973599/
  4. Dec 2023
  5. www.sciencedirect.com www.sciencedirect.com
    An enzyme that selectively S-nitrosylates proteins to regulate insulin signaling
    1
    1. scibot 20 Dec 2023
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.cell.2023.11.009

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    sciencedirect.com/science/article/pii/S0092867423012266
  6. Sep 2023
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficacy of oseltamivir treatment in influenza virus-infected obese mice
    1
    1. scibot 07 Sep 2023
      JAX:000632

      DOI: 10.1128/mbio.00887-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC10470499/
  8. Jun 2023
  9. www.sciencedirect.com www.sciencedirect.com
    Defective extracellular matrix remodeling in brown adipose tissue is associated with fibro-inflammation and reduced diet-induced thermogenesis
    1
    1. scibot 22 Jun 2023
      RRID:IMSR_JAX

      DOI: 10.1016/j.celrep.2023.112640

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      Curator: @jmitrevska

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    sciencedirect.com/science/article/pii/S2211124723006514
  10. Mar 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Monitoring autophagic flux in vivo revealed its physiological response and significance of heterogeneity in pancreatic beta cells
    1
    1. scibot 28 Mar 2023
      JAX:000632

      DOI: 10.1016/j.chembiol.2023.03.001

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    sciencedirect.com/science/article/pii/S2451945623000600
  12. www.sciencedirect.com www.sciencedirect.com
    Rapid and fully automated blood vasculature analysis in 3D light-sheet image volumes of different organs
    1
    1. scibot 18 Mar 2023
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.crmeth.2023.100436

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    sciencedirect.com/science/article/pii/S2667237523000516
  13. Feb 2023
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stress Granules determine the Development of Obesity-associated Pancreatic Cancer
    1
    1. scibot 09 Feb 2023
      JAX:000632

      DOI: 10.1158/2159-8290.CD-21-1672

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    ncbi.nlm.nih.gov/pmc/articles/PMC9357213/
  15. Oct 2022
  16. www.sciencedirect.com www.sciencedirect.com
    The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic effects in obese mice
    1
    1. scibot 18 Oct 2022
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.cmet.2022.09.019

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    sciencedirect.com/science/article/pii/S1550413122004090
  17. www.sciencedirect.com www.sciencedirect.com
    The gut peptide Reg3g links the small intestine microbiome to the regulation of energy balance, glucose levels, and gut function
    1
    1. scibot 15 Oct 2022
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.cmet.2022.09.024

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    sciencedirect.com/science/article/pii/S155041312200448X
  18. www.sciencedirect.com www.sciencedirect.com
    Obesity caused by an OVOL2 mutation reveals dual roles of OVOL2 in promoting thermogenesis and limiting white adipogenesis
    1
    1. scibot 13 Oct 2022
      000632

      DOI: 10.1016/j.cmet.2022.09.018

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      Curator: @a5munoz

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    sciencedirect.com/science/article/pii/S1550413122004089
  19. Aug 2022
  20. www.sciencedirect.com www.sciencedirect.com
    The mitochondrial calcium uniporter engages UCP1 to form a thermoporter that promotes thermogenesis
    1
    1. scibot 17 Aug 2022
      The Jackson LaboratoryStock No. 000632

      DOI: 10.1016/j.cmet.2022.07.011

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      Curator: @sophiastull

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    sciencedirect.com/science/article/pii/S1550413122003102
  21. Jul 2022
  22. www.sciencedirect.com www.sciencedirect.com
    FKBP11 rewires UPR signaling to promote glucose homeostasis in type 2 diabetes and obesity
    1
    1. scibot 06 Jul 2022
      JAX:000632

      DOI: 10.1016/j.cmet.2022.06.007

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    sciencedirect.com/science/article/pii/S1550413122002273
  23. Apr 2022
  24. www.sciencedirect.com www.sciencedirect.com
    Inducing and measuring apoptotic cell death in mouse pancreatic β-cells and in isolated islets
    1
    1. scibot 15 Apr 2022
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.xpro.2022.101287

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    sciencedirect.com/science/article/pii/S2666166722001678
  25. www.sciencedirect.com www.sciencedirect.com
    Three-dimensional volume fluorescence-imaging of vascular plasticity in adipose tissues
    1
    1. scibot 05 Apr 2022
      JAX:000632

      DOI: 10.1016/j.molmet.2018.06.004

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    sciencedirect.com/science/article/pii/S2212877818304447
  26. Mar 2022
  27. www.sciencedirect.com www.sciencedirect.com
    Amelioration of hepatic steatosis by dietary essential amino acid-induced ubiquitination
    1
    1. scibot 04 Mar 2022
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.molcel.2022.01.021

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    sciencedirect.com/science/article/pii/S1097276522000867
  28. Feb 2022
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms
    1
    1. scibot 08 Feb 2022
      RRID:MGI:6719537

      DOI: 10.7554/eLife.63998

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC8813054/
  30. Jan 2022
  31. www.sciencedirect.com www.sciencedirect.com
    FGF1 and insulin control lipolysis by convergent pathways
    1
    1. scibot 05 Jan 2022
      000632

      DOI: 10.1016/j.cmet.2021.12.004

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    sciencedirect.com/science/article/pii/S1550413121006239
  32. Nov 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Vaccine targeting ANGPTL3 ameliorates dyslipidemia and associated diseases in mouse models of obese dyslipidemia and familial hypercholesterolemia
    1
    1. scibot 17 Nov 2021
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.xcrm.2021.100446

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    sciencedirect.com/science/article/pii/S2666379121003141
  34. www.sciencedirect.com www.sciencedirect.com
    Dissecting mammalian spermatogenesis using spatial transcriptomics
    1
    1. scibot 03 Nov 2021
      000632

      DOI: 10.1016/j.celrep.2021.109915

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    sciencedirect.com/science/article/pii/S2211124721013887
  35. Sep 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation
    1
    1. scibot 08 Sep 2021
      Stock No: 000632

      DOI: 10.1016/j.celrep.2021.109659

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    sciencedirect.com/science/article/pii/S2211124721011037
  37. Aug 2021
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity
    1
    1. scibot 14 Aug 2021
      JAX:000632

      DOI: 10.1016/j.cmet.2018.12.003

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    ncbi.nlm.nih.gov/pmc/articles/PMC6701710/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 11 Aug 2021
      RRID:IMSR_JAX:000632

      DOI: 10.1002/cne.24327

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    ncbi.nlm.nih.gov/pmc/articles/PMC6040218/
  40. Jul 2021
  41. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    1. scibot 31 Jul 2021
      RRID:IMSR_JAX:000632

      DOI: 10.1002/cne.24327

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    onlinelibrary.wiley.com/doi/abs/10.1002/cne.24327
  42. www.sciencedirect.com www.sciencedirect.com
    Identification of a Paracrine Signaling Mechanism Linking CD34high Progenitors to the Regulation of Visceral Fat Expansion and Remodeling
    1
    1. scibot 29 Jul 2021
      The Jackson Laboratory#000632

      DOI: 10.1016/j.celrep.2019.08.092

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2211124719311544
  43. www.sciencedirect.com www.sciencedirect.com
    Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction
    1
    1. scibot 29 Jul 2021
      Jackson LabsCat. 000632

      DOI: 10.1016/j.cmet.2019.08.021

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    sciencedirect.com/science/article/pii/S1550413119304954
  44. www.sciencedirect.com www.sciencedirect.com
    Glycogen Synthase Kinase-3α Promotes Fatty Acid Uptake and Lipotoxic Cardiomyopathy
    1
    1. scibot 28 Jul 2021
      JAX 000632

      DOI: 10.1016/j.cmet.2019.01.005

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    sciencedirect.com/science/article/pii/S1550413119300051
  45. www.sciencedirect.com www.sciencedirect.com
    Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence
    1
    1. scibot 14 Jul 2021
      Cat# 000632

      DOI: 10.1016/j.celrep.2021.109362

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    sciencedirect.com/science/article/pii/S2211124721007609
  46. May 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation
    1
    1. scibot 19 May 2021
      Cat.# 000632

      DOI: 10.1016/j.chom.2021.04.004

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    sciencedirect.com/science/article/pii/S1931312821001803
  48. www.sciencedirect.com www.sciencedirect.com
    Fasting reduces the number of TRH immunoreactive neurons in the hypothalamic paraventricular nucleus of male rats, but not in mice
    1
    1. scibot 08 May 2021
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.neulet.2021.135832

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    sciencedirect.com/science/article/pii/S030439402100210X
  49. www.sciencedirect.com www.sciencedirect.com
    Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis
    1
    1. scibot 06 May 2021
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.immuni.2020.06.003

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    sciencedirect.com/science/article/pii/S1074761320302338
  50. www.sciencedirect.com www.sciencedirect.com
    Metabolic stress drives sympathetic neuropathy within the liver
    1
    1. scibot 01 May 2021
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.cmet.2021.01.012

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    sciencedirect.com/science/article/pii/S1550413121000127
  51. Apr 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity
    1
    1. scibot 29 Apr 2021
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.cmet.2020.04.020

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    sciencedirect.com/science/article/pii/S1550413120302370
  53. www.sciencedirect.com www.sciencedirect.com
    Identification of ALK in Thinness
    1
    1. scibot 23 Apr 2021
      Stock No 000632

      DOI: 10.1016/j.cell.2020.04.034

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    sciencedirect.com/science/article/pii/S0092867420304979
  54. www.sciencedirect.com www.sciencedirect.com
    Conversion of the death inhibitor ARC to a killer activates pancreatic β cell death in diabetes
    1
    1. scibot 19 Apr 2021
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.devcel.2021.02.011

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    sciencedirect.com/science/article/pii/S1534580721001222
  55. www.sciencedirect.com www.sciencedirect.com
    An optimized protocol for establishing a chronic stress model in mice
    1
    1. scibot 14 Apr 2021
      Cat# 000632

      DOI: 10.1016/j.xpro.2021.100448

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    sciencedirect.com/science/article/pii/S2666166721001556
  56. Mar 2021
  57. www.sciencedirect.com www.sciencedirect.com
    Phenotypic characterization of Adig null mice suggests roles for adipogenin in the regulation of fat mass accrual and leptin secretion
    1
    1. scibot 10 Mar 2021
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.celrep.2021.108810

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    sciencedirect.com/science/article/pii/S2211124721001248
  58. Feb 2021
  59. www.sciencedirect.com www.sciencedirect.com
    The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages
    1
    1. scibot 25 Feb 2021
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.molcel.2020.12.040

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    sciencedirect.com/science/article/pii/S1097276520309618
  60. Nov 2020
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leptin suppresses development of GLP-1 inputs to the paraventricular nucleus of the hypothalamus
    1
    1. scibot 26 Nov 2020
      RRID:IMSR_JAX:000632

      DOI: 10.7554/eLife.59857

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    ncbi.nlm.nih.gov/pmc/articles/PMC7673779/
  62. Sep 2020
  63. www.sciencedirect.com www.sciencedirect.com
    Secreted Phospholipase PLA2G2D Contributes to Metabolic Health by Mobilizing ω3 Polyunsaturated Fatty Acids in WAT
    1
    1. scibot 23 Sep 2020
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.celrep.2020.107579

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    sciencedirect.com/science/article/pii/S2211124720305283
  64. www.sciencedirect.com www.sciencedirect.com
    Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma
    1
    1. scibot 15 Sep 2020
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.cell.2020.03.062

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    sciencedirect.com/science/article/pii/S0092867420303950
  65. academic.oup.com academic.oup.com
    Gut hormone GIP induces inflammation and insulin resistance in the hypothalamus
    1
    1. scibot 03 Sep 2020
      ob/ob

      DOI: 10.1210/endocr/bqaa102

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      Curator: @Naa003

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    academic.oup.com/endo/article/161/9/bqaa102/5865317
  66. Aug 2020
  67. mbio.asm.org mbio.asm.org
    Obesity-Related Microenvironment Promotes Emergence of Virulent Influenza Virus Strains
    1
    1. scibot 31 Aug 2020
      JAX 000632

      DOI: 10.1128/mBio.03341-19

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    mbio.asm.org/content/11/2/e03341-19
  68. Jan 2020
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long-term consequences of the absence of leptin signaling in early life
    1
    1. scibot 13 Jan 2020
      JAX:000632

      DOI: 10.7554/eLife.40970

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    ncbi.nlm.nih.gov/pmc/articles/PMC6384028/
  70. elifesciences.org elifesciences.org
    Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:000632

      DOI: 10.7554/eLife.47990

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    elifesciences.org/articles/47990
  71. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 12 Jan 2020
      RRID:IMSR_JAX:000632

      DOI: 10.1016/j.cell.2019.02.030

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    sciencedirect.com/science/article/pii/S0092867419302132
  72. Nov 2018
  73. elifesciences.org elifesciences.org
    The adipocyte hormone leptin sets the emergence of hippocampal inhibition in mice
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:000632

      Curator: @evieth

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    elifesciences.org/articles/36726
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 05 Nov 2018
      JAX:000632

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    ncbi.nlm.nih.gov/pmc/articles/PMC6034070/
  75. www.sciencedirect.com www.sciencedirect.com
    Evidence for a Non-leptin System that Defends against Weight Gain in Overfeeding
    1
    1. scibot 05 Nov 2018
      000632

      Curator: @Jmenke

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      RRID:IMSR_JAX:000632 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1550413118303826
  76. Nov 2017
  77. www.sciencedirect.com www.sciencedirect.com
    Dynamics of Gut-Brain Communication Underlying Hunger
    1
    1. scibot 08 Nov 2017
      RRID:IMSR_JAX:000632

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0896627317309121
  78. www.sciencedirect.com www.sciencedirect.com
    Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity
    1
    1. scibot 08 Nov 2017
      JAX:000632

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    sciencedirect.com/science/article/pii/S1550413117305508
  79. www.sciencedirect.com www.sciencedirect.com
    Dense Intra-adipose Sympathetic Arborizations Are Essential for Cold-Induced Beiging of Mouse White Adipose Tissue
    1
    1. scibot 08 Nov 2017
      JAX:000632

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1550413117305016
  80. www.sciencedirect.com www.sciencedirect.com
    The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency
    1
    1. scibot 08 Nov 2017
      JAX: 000632

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S2451945617301095
  81. www.sciencedirect.com www.sciencedirect.com
    Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation
    1
    1. scibot 08 Nov 2017
      lep+/ob heterozygous miceJackson LaboratoriesCat#000632

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1550413117304308
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An alternative splicing program promotes adipose tissue thermogenesis
    1
    1. scibot 08 Nov 2017
      IMSR_JAX:000632

      Curator: @gabimpine

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    ncbi.nlm.nih.gov/pmc/articles/PMC5026472/
  83. www.sciencedirect.com www.sciencedirect.com
    Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes
    1
    1. scibot 08 Nov 2017
      000632

      Curator: @Zeljana_Babic

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      RRID:IMSR_JAX:000632

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    sciencedirect.com/science/article/pii/S0092867417302490