41 Matching Annotations
  1. Oct 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Small molecules targeting selective PCK1 and PGC-1α lysine acetylation cause anti-diabetic action through increased lactate oxidation
    1
    1. scibot 02 Oct 2024
      Jackson Laboratory Cat_000697

      DOI: 10.1016/j.chembiol.2024.09.001

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    sciencedirect.com/science/article/pii/S2451945624003933
  3. Aug 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Obesity intensifies sex-specific interferon signaling to selectively worsen central nervous system autoimmunity in females
    1
    1. scibot 22 Aug 2024
      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.cmet.2024.07.017

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    sciencedirect.com/science/article/pii/S1550413124002882
  5. May 2024
  6. www.sciencedirect.com www.sciencedirect.com
    G-protein-coupled receptor 84 regulates acute inflammation in normal and diabetic skin wounds
    1
    1. scibot 30 May 2024
      000697

      DOI: 10.1016/j.celrep.2024.114288

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    sciencedirect.com/science/article/pii/S2211124724006168
  7. www.sciencedirect.com www.sciencedirect.com
    Bone transport induces the release of factors with multi-tissue regenerative potential for diabetic wound healing in rats and patients
    1
    1. scibot 23 May 2024
      JAX:000697

      DOI: 10.1016/j.xcrm.2024.101588

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    sciencedirect.com/science/article/pii/S2666379124002805
  8. Apr 2024
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Krüppel-like factor 10 protects against metabolic dysfunction-associated steatohepatitis by regulating HNF4α-mediated metabolic pathways
    1
    1. scibot 10 Apr 2024
      000697

      DOI: 10.1016/j.metabol.2024.155909

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    pmc.ncbi.nlm.nih.gov/articles/PMC11178432/
  10. www.sciencedirect.com www.sciencedirect.com
    Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss
    1
    1. scibot 04 Apr 2024
      Strain #:000697

      DOI: 10.1016/j.cmet.2024.02.007

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    sciencedirect.com/science/article/pii/S1550413124000536
  11. Nov 2023
  12. www.sciencedirect.com www.sciencedirect.com
    The Role of KLF2 in Regulating Hepatic Lipogenesis and Blood Cholesterol Homeostasis via the SCAP/SREBP Pathway
    1
    1. scibot 17 Nov 2023
      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.jlr.2023.100472

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    sciencedirect.com/science/article/pii/S0022227523001451
  13. Jun 2023
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tubular IL-1β Induces Salt Sensitivity in Diabetes by Activating Renal Macrophages
    1
    1. scibot 27 Jun 2023
      RRID:IMSR_JAX:000697

      DOI: 10.1161/CIRCRESAHA.121.320239

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    ncbi.nlm.nih.gov/pmc/articles/PMC9233055/
  15. Aug 2022
  16. www.sciencedirect.com www.sciencedirect.com
    Hepatocyte Rap1a contributes to obesity- and statin-associated hyperglycemia
    1
    1. scibot 26 Aug 2022
      JAX:000697

      DOI: 10.1016/j.celrep.2022.111259

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    sciencedirect.com/science/article/pii/S2211124722010774
  17. www.sciencedirect.com www.sciencedirect.com
    In vivo drug discovery for increasing incretin-expressing cells identifies DYRK inhibitors that reinforce the enteroendocrine system
    1
    1. scibot 23 Aug 2022
      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.chembiol.2022.08.001

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    sciencedirect.com/science/article/pii/S245194562200277X
  18. Jul 2022
  19. 52.53.155.43 52.53.155.43
    Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome
    1
    1. scibot 29 Jul 2022
      RRID:IMSR_JAX:000697

      DOI: 10.2337/db22-0260

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    52.53.155.43/72094a1fe18d13f5780e59dcdef493f11f57b326/db220260-html.html
  20. Jun 2022
  21. www.sciencedirect.com www.sciencedirect.com
    A protocol to induce systemic autophagy and increase energy metabolism in mice using PEGylated arginine deiminase
    1
    1. scibot 25 Jun 2022
      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.xpro.2022.101489

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    sciencedirect.com/science/article/pii/S2666166722003690
  22. www.sciencedirect.com www.sciencedirect.com
    Glucagon-receptor-antagonism-mediated β-cell regeneration as an effective anti-diabetic therapy
    1
    1. scibot 03 Jun 2022
      JAX000697

      DOI: 10.1016/j.celrep.2022.110872

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      Curator: @sophiastull

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    sciencedirect.com/science/article/pii/S2211124722006477
  23. Apr 2022
  24. www.sciencedirect.com www.sciencedirect.com
    Three-dimensional volume fluorescence-imaging of vascular plasticity in adipose tissues
    1
    1. scibot 05 Apr 2022
      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.molmet.2018.06.004

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    sciencedirect.com/science/article/pii/S2212877818304447
  25. Jan 2022
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kir6.2-deficient mice develop somatosensory dysfunction and axonal loss in the peripheral nerves.
    1
    1. scibot 11 Jan 2022
      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.isci.2021.103609

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    ncbi.nlm.nih.gov/pmc/articles/PMC8719014/
  27. Oct 2021
  28. www.sciencedirect.com www.sciencedirect.com
    A synaptic temperature sensor for body cooling
    1
    1. scibot 21 Oct 2021
      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.neuron.2021.10.001

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    sciencedirect.com/science/article/pii/S0896627321007698
  29. Sep 2021
  30. www.sciencedirect.com www.sciencedirect.com
    Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis
    1
    1. scibot 17 Sep 2021
      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.stem.2021.08.007

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    sciencedirect.com/science/article/pii/S1934590921003441
  31. Jul 2021
  32. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas
    1
    1. scibot 30 Jul 2021
      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.devcel.2018.11.001

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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1534580718309195
  33. www.sciencedirect.com www.sciencedirect.com
    Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner
    1
    1. scibot 29 Jul 2021
      Mouse: B6.BKS(D)-Leprdb/J (B6 db)

      DOI: 10.1016/j.cell.2019.05.054

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S0092867419306257
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 29 Jul 2021
      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.molmet.2018.06.004

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC6034070/
  35. www.sciencedirect.com www.sciencedirect.com
    Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis
    1
    1. scibot 28 Jul 2021
      000697

      DOI: 10.1016/j.cmet.2018.12.008

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    sciencedirect.com/science/article/pii/S1550413118307459
  36. www.sciencedirect.com www.sciencedirect.com
    Circulating Levels of Soluble Dipeptidyl Peptidase-4 Are Dissociated from Inflammation and Induced by Enzymatic DPP4 Inhibition
    1
    1. scibot 27 Jul 2021
      000697

      DOI: 10.1016/j.cmet.2018.10.001

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    sciencedirect.com/science/article/pii/S1550413118306338
  37. Jun 2021
  38. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    SIRT6 transcriptionally regulates fatty acid transport by suppressing PPARγ
    1
    1. scibot 02 Jun 2021
      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.celrep.2021.109190

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    pubmed.ncbi.nlm.nih.gov/34077730/
  39. May 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation
    1
    1. scibot 19 May 2021
      Cat.# 000697

      DOI: 10.1016/j.chom.2021.04.004

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    sciencedirect.com/science/article/pii/S1931312821001803
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Asprosin-neutralizing antibodies as a treatment for metabolic syndrome
    1
    1. scibot 13 May 2021
      RRID:IMSR_JAX:000697

      DOI: 10.7554/eLife.63784

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    ncbi.nlm.nih.gov/pmc/articles/PMC8102062/
  42. www.sciencedirect.com www.sciencedirect.com
    Metabolic stress drives sympathetic neuropathy within the liver
    1
    1. scibot 01 May 2021
      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.cmet.2021.01.012

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    sciencedirect.com/science/article/pii/S1550413121000127
  43. Apr 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes
    1
    1. scibot 29 Apr 2021
      #000697

      DOI: 10.1016/j.cmet.2020.09.012

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    sciencedirect.com/science/article/pii/S1550413120304903
  45. www.sciencedirect.com www.sciencedirect.com
    Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action
    1
    1. scibot 29 Apr 2021
      000697

      DOI: 10.1016/j.cmet.2020.07.002

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    sciencedirect.com/science/article/pii/S1550413120303600
  46. www.sciencedirect.com www.sciencedirect.com
    Conversion of the death inhibitor ARC to a killer activates pancreatic β cell death in diabetes
    2
    1. scibot 20 Apr 2021
      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.devcel.2021.02.011

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    2. scibot 19 Apr 2021
      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.devcel.2021.02.011

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    sciencedirect.com/science/article/pii/S1534580721001222
  47. Mar 2021
  48. link.springer.com link.springer.com
    Fasting and fasting-mimicking treatment activate SIRT1/LXRα and alleviate diabetes-induced systemic and microvascular dysfunction
    1
    1. scibot 30 Mar 2021
      stock #000697

      DOI: 10.1007/s00125-021-05431-5

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    link.springer.com/article/10.1007/s00125-021-05431-5
  49. Sep 2020
  50. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sophoricoside is a selective LXRβ antagonist with potent therapeutic effects on hepatic steatosis of mice
    1
    1. scibot 23 Sep 2020
      RRID:IMSR_JAX:000697

      DOI: 10.1002/ptr.6747

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    onlinelibrary.wiley.com/doi/10.1002/ptr.6747
  51. www.sciencedirect.com www.sciencedirect.com
    Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma
    1
    1. scibot 15 Sep 2020
      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.cell.2020.03.062

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    sciencedirect.com/science/article/pii/S0092867420303950
  52. link.springer.com link.springer.com
    Islet pericytes convert into profibrotic myofibroblasts in a mouse model of islet vascular fibrosis
    1
    1. scibot 04 Sep 2020
      stock no. 000697

      DOI: 10.1007/s00125-020-05168-7

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    link.springer.com/article/10.1007/s00125-020-05168-7
  53. www.sciencedirect.com www.sciencedirect.com
    Zonation of Pancreatic Acinar Cells in Diabetic Mice
    1
    1. scibot 03 Sep 2020
      B6.BKS(D)-Leprdb/J mice

      DOI: 10.1016/j.celrep.2020.108043

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    sciencedirect.com/science/article/pii/S2211124720310287
  54. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Microbial Imidazole Propionate Affects Responses to Metformin through p38γ-Dependent Inhibitory AMPK Phosphorylation
    1
    1. scibot 03 Sep 2020
      db/db mice

      DOI: 10.1016/j.cmet.2020.07.012

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    pubmed.ncbi.nlm.nih.gov/32783890/
  55. www.sciencedirect.com www.sciencedirect.com
    The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress
    1
    1. scibot 03 Sep 2020
      Mouse Diabetic db/db B6.BKS(D)-Leprdb/J

      DOI: 10.1016/j.celrep.2020.107846

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      RRID:IMSR_JAX:000697 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2211124720308275
  56. Jan 2020
  57. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas
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      RRID:IMSR_JAX:000697

      DOI: 10.1016/j.devcel.2018.11.001

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    sciencedirect.com/science/article/pii/S1534580718309195
  58. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Hydrogen sulfide regulates muscle RING finger‐1 protein S‐sulfhydration at Cys44 to prevent cardiac structural damage in diabetic cardiomyopathy
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    1. scibot 12 Jan 2020
      RRID:IMSR_JAX:000697

      DOI: 10.1111/bph.14601

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      Curator: @Naa003

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14601
  59. Nov 2018
  60. elifesciences.org elifesciences.org
    The adipocyte hormone leptin sets the emergence of hippocampal inhibition in mice
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      Curator: @evieth

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    elifesciences.org/articles/36726
  61. www.jneurosci.org www.jneurosci.org
    Untitled document
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    jneurosci.org/content/37/49/11854