111 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Identification of cells of leukemic stem cell origin with non-canonical regenerative properties
    1
    1. scibot 09 Apr 2024
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.xcrm.2024.101485

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    sciencedirect.com/science/article/pii/S2666379124001319
  3. www.sciencedirect.com www.sciencedirect.com
    Oncostatin M signaling drives cancer-associated skeletal muscle wasting
    1
    1. scibot 05 Apr 2024
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.xcrm.2024.101498

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    sciencedirect.com/science/article/pii/S2666379124001666
  4. Mar 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors
    1
    1. scibot 06 Mar 2024
      RRID:IMSR_JAX:001303

      DOI: 10.1158/2159-8290.CD-23-0954

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    ncbi.nlm.nih.gov/pmc/articles/PMC10905675/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification and characterization of a small molecule Bcl-2 Functional Converter
    1
    1. scibot 06 Mar 2024
      JAX:001303

      DOI: 10.1158/2767-9764.CRC-22-0526

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    ncbi.nlm.nih.gov/pmc/articles/PMC10911799/
  7. Feb 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An integrative proteomics approach identifies tyrosine kinase KIT as a therapeutic target for SPINK1-positive prostate cancer
    1
    1. scibot 28 Feb 2024
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.isci.2024.108794

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879682/
  9. 52.53.155.43 52.53.155.43
    cd-23-0954-html.html
    1
    1. scibot 27 Feb 2024
      RRID:IMSR_JAX:001303

      DOI: 10.1158/2159-8290.cd-23-0954

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    52.53.155.43/aaf525c30ae01b53e260240fad732783dfb4bbac/cd-23-0954-html.html
  10. link.springer.com link.springer.com
    TYK2 signaling promotes the development of autoreactive CD8+ cytotoxic T lymphocytes and type 1 diabetes
    1
    1. scibot 15 Feb 2024
      RRID:IMSR_JAX:001303

      DOI: 10.1038/s41467-024-45573-9

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    link.springer.com/article/10.1038/s41467-024-45573-9
  11. link.springer.com link.springer.com
    Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer
    1
    1. scibot 07 Feb 2024
      RRID:IMSR_JAX:001303

      DOI: 10.1186/s12935-024-03231-6

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    link.springer.com/article/10.1186/s12935-024-03231-6
  12. Jan 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer
    1
    1. scibot 06 Jan 2024
      The Jackson Laboratory001303

      DOI: 10.1016/j.cmet.2023.12.003

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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S1550413123004552
  14. Dec 2023
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Master transcription factor reprograming unleashes selective translation promoting castration resistance and immune evasion in lethal prostate cancer.
    1
    1. scibot 15 Dec 2023
      RRID:IMSR_JAX:001303

      DOI: 10.1158/2159-8290.CD-23-0306

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    ncbi.nlm.nih.gov/pmc/articles/PMC10714140/
  16. 52.53.155.43 52.53.155.43
    cd-23-0306-html.html
    1
    1. scibot 01 Dec 2023
      RRID:IMSR_JAX

      DOI: 10.1158/2159-8290.cd-23-0306

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    52.53.155.43/2d1591f4bcff82c10886f9ef5d1f22c1addeb365/cd-23-0306-html.html
  17. Nov 2023
  18. www.sciencedirect.com www.sciencedirect.com
    TGFB1 induces fetal reprogramming and enhances intestinal regeneration
    1
    1. scibot 10 Nov 2023
      JAX:001303

      DOI: 10.1016/j.stem.2023.09.015

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    sciencedirect.com/science/article/pii/S1934590923003624
  19. Sep 2023
  20. www.embopress.org www.embopress.org
    mAb therapy controls CNS-resident lyssavirus infection via a CD4 T cell-dependent mechanism
    1
    1. scibot 29 Sep 2023
      RRID:IMSR_JAX:001303

      DOI: 10.15252/emmm.202216394

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    embopress.org/doi/10.15252/emmm.202216394
  21. Aug 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leukemic progenitor compartment serves as a prognostic measure of cancer stemness in patients with acute myeloid leukemia
    1
    1. scibot 04 Aug 2023
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.xcrm.2023.101108

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    ncbi.nlm.nih.gov/pmc/articles/PMC10394166/
  23. Jul 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caffeine supplementation and FOXM1 inhibition enhance the antitumor effect of statins in neuroblastoma
    1
    1. scibot 08 Jul 2023
      RRID:IMSR_JAX:001303

      DOI: 10.1158/0008-5472.CAN-22-3450

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    ncbi.nlm.nih.gov/pmc/articles/PMC10320471/
  25. Jun 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Deep Learning Enabled Quantification of Simultaneous PET/MRI for Cell Transplantation Monitoring
    1
    1. scibot 27 Jun 2023
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.isci.2023.107083

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    sciencedirect.com/science/article/pii/S2589004223011604
  27. 52.53.155.43 52.53.155.43
    can-22-3450-html.html
    1
    1. scibot 01 Jun 2023
      RRID:IMSR_JAX:001303

      DOI: 10.1158/0008-5472.CAN-22-3450

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    52.53.155.43/d74c78a2e62f04f8ffa00018470c131fb0d65945/can-22-3450-html.html
  28. May 2023
  29. www.sciencedirect.com www.sciencedirect.com
    An in vivo neuroimmune organoid model to study human microglia phenotypes
    1
    1. scibot 12 May 2023
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.cell.2023.04.022

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    sciencedirect.com/science/article/pii/S009286742300418X
  30. Apr 2023
  31. www.science.org www.science.org
    An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation
    2
    1. scibot 27 Apr 2023
      RRID:IMSR_JAX:001303

      DOI: 10.1126/sciadv.adf8966

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    2. scibot 27 Apr 2023
      RRID:IMSR_JAX:001303

      DOI: 10.1126/sciadv.adf8966

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    science.org/doi/10.1126/sciadv.adf8966
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
    1
    1. scibot 20 Apr 2023
      RRID:IMSR_JAX:001303

      DOI: 10.1158/2767-9764.CRC-22-0310

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    ncbi.nlm.nih.gov/pmc/articles/PMC10112292/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SGN-CD228A Is an Investigational CD228-Directed Antibody–Drug Conjugate with Potent Antitumor Activity across a Wide Spectrum of Preclinical Solid Tumor Models
    1
    1. scibot 12 Apr 2023
      RRID:IMSR_JAX:001303

      DOI: 10.1158/1535-7163.MCT-22-0401

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    ncbi.nlm.nih.gov/pmc/articles/PMC10068445/
  34. Mar 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Isolation of slow-cycling cancer cells from lung patient-derived xenograft using carboxyfluorescein-succinimidyl ester retention-mediated cell sorting
    1
    1. scibot 16 Mar 2023
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.xpro.2023.102167

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    sciencedirect.com/science/article/pii/S2666166723001259
  36. Feb 2023
  37. www.sciencedirect.com www.sciencedirect.com
    DRAK2 contributes to type 1 diabetes by negatively regulating IL-2 sensitivity to alter regulatory T cell development
    1
    1. scibot 17 Feb 2023
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.celrep.2023.112106

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    sciencedirect.com/science/article/pii/S2211124723001171
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of iNOS/NO Promotes Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer
    1
    1. scibot 09 Feb 2023
      RRID:IMSR-JAX

      DOI: 10.1158/1541-7786.MCR-22-0509

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC9890133/
  39. Jan 2023
  40. journals.biologists.com journals.biologists.com
    HES1 promoter activation dynamics reveal the plasticity, stemness and heterogeneity in neuroblastoma cancer stem cells
    1
    1. scibot 21 Jan 2023
      RRID:IMSR_JAX:001303

      DOI: 10.1242/jcs.260157

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    journals.biologists.com/jcs/article/135/22/jcs260157/283156/HES1-promoter-activation-dynamics-reveal-the
  41. www.sciencedirect.com www.sciencedirect.com
    Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes
    1
    1. scibot 05 Jan 2023
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.chom.2022.12.009

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    sciencedirect.com/science/article/pii/S1931312822006102
  42. Nov 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis
    1
    1. scibot 16 Nov 2022
      001303

      DOI: 10.1016/j.celrep.2022.111672

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    sciencedirect.com/science/article/pii/S2211124722015467
  44. Aug 2022
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting ribonucleotide reductase induces synthetic lethality in PP2A-deficient uterine serous carcinoma
    1
    1. scibot 22 Aug 2022
      JAX:001303

      DOI: 10.1158/0008-5472.CAN-21-1987

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    ncbi.nlm.nih.gov/pmc/articles/PMC8857033/
  46. www.sciencedirect.com www.sciencedirect.com
    Herpesvirus-induced spermidine synthesis and eIF5A hypusination for viral episomal maintenance
    1
    1. scibot 17 Aug 2022
      The Jackson Laboratory001303

      DOI: 10.1016/j.celrep.2022.111234

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    sciencedirect.com/science/article/pii/S2211124722010518
  47. aacrjournals.org aacrjournals.org
    Proteomic mapping and targeting of mitotic pericentriolar material in tumors bearing centrosome amplification
    1
    1. scibot 16 Aug 2022
      RRID:IMSR_JAX:001303

      DOI: 10.1158/0008-5472.CAN-22-0225

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    aacrjournals.org/cancerres/article/82/14/2576/706950/Proteomic-Mapping-and-Targeting-of-Mitotic
  48. Jul 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer
    1
    1. scibot 30 Jul 2022
      Jackson Labs001303

      DOI: 10.1016/j.celrep.2022.111066

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    sciencedirect.com/science/article/pii/S2211124722008646
  50. www.sciencedirect.com www.sciencedirect.com
    Small intestinal resident eosinophils maintain gut homeostasis following microbial colonization
    1
    1. scibot 08 Jul 2022
      JAX Stock: 001303

      DOI: 10.1016/j.immuni.2022.05.014

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    sciencedirect.com/science/article/pii/S1074761322002345
  51. Jun 2022
  52. www.sciencedirect.com www.sciencedirect.com
    G6PD inhibition sensitizes ovarian cancer cells to oxidative stress in the metastatic omental microenvironment
    1
    1. scibot 29 Jun 2022
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.celrep.2022.111012

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    sciencedirect.com/science/article/pii/S2211124722008014
  53. May 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Gold(III)-P-chirogenic complex induce mitochondrial dysfunction in triple-negative breast cancer
    1
    1. scibot 19 May 2022
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.isci.2022.104340

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    sciencedirect.com/science/article/pii/S2589004222006113
  55. Apr 2022
  56. www.sciencedirect.com www.sciencedirect.com
    Microbial byproducts determine reproductive fitness of free-living and parasitic nematodes
    1
    1. scibot 15 Apr 2022
      JAX:001303

      DOI: 10.1016/j.chom.2022.03.015

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    sciencedirect.com/science/article/pii/S1931312822001457
  57. Mar 2022
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Murine glial progenitor cells transplantation and synthetic PreImplantation Factor (sPIF) reduces inflammation and early motor impairment in ALS mice
    1
    1. scibot 11 Mar 2022
      RRID:IMSR_JAX:001303

      DOI: 10.1038/s41598-022-08064-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC8901633/
  59. Feb 2022
  60. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling
    1
    1. scibot 16 Feb 2022
      The Jackson LaboratoriesStrain#001303

      DOI: 10.1016/j.celrep.2022.110395

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  61. www.sciencedirect.com www.sciencedirect.com
    Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity
    2
    1. scibot 11 Feb 2022
      001303

      DOI: 10.1016/j.devcel.2022.01.006

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    2. scibot 09 Feb 2022
      001303

      DOI: 10.1016/j.devcel.2022.01.006

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    sciencedirect.com/science/article/pii/S1534580722000065
  62. Jan 2022
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unique Sensitivity of Uterine Tissue and the Immune System for Endometriotic Lesion Formation
    1
    1. scibot 05 Jan 2022
      RRID:IMSR_JAX:001303

      DOI: 10.3389/fphys.2021.805784

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    ncbi.nlm.nih.gov/pmc/articles/PMC8719640/
  64. www.sciencedirect.com www.sciencedirect.com
    AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia
    1
    1. scibot 05 Jan 2022
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.celrep.2021.110197

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    sciencedirect.com/science/article/pii/S2211124721017010
  65. Dec 2021
  66. www.sciencedirect.com www.sciencedirect.com
    Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis
    1
    1. scibot 08 Dec 2021
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.celrep.2021.110099

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    sciencedirect.com/science/article/pii/S221112472101593X
  67. Nov 2021
  68. www.sciencedirect.com www.sciencedirect.com
    Long-term selective stimulation of transplanted neural stem/progenitor cells for spinal cord injury improves locomotor function
    1
    1. scibot 24 Nov 2021
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.celrep.2021.110019

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  69. Oct 2021
  70. www.science.org www.science.org
    Therapeutic targeting of SLC6A8 creatine transporter suppresses colon cancer progression and modulates human creatine levels
    1
    1. scibot 18 Oct 2021
      001303

      DOI: 10.1126/sciadv.abi7511

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    science.org/doi/10.1126/sciadv.abi7511
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic targeting of SLC6A8 creatine transporter suppresses colon cancer progression and modulates human creatine levels
    1
    1. scibot 15 Oct 2021
      JAX stock #001303

      DOI: 10.1126/sciadv.abi7511

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    ncbi.nlm.nih.gov/pmc/articles/PMC8494442/
  72. www.sciencedirect.com www.sciencedirect.com
    Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells
    1
    1. scibot 13 Oct 2021
      001303

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    sciencedirect.com/science/article/pii/S2211124721012766
  73. Sep 2021
  74. www.sciencedirect.com www.sciencedirect.com
    Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations
    1
    1. scibot 08 Sep 2021
      Stock No: 001303

      DOI: 10.1016/j.celrep.2021.109673

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    sciencedirect.com/science/article/pii/S2211124721011177
  75. Aug 2021
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 04 Aug 2021
      RRID:IMSR_JAX:001303

      DOI: 10.7554/eLife.25306

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    ncbi.nlm.nih.gov/pmc/articles/PMC5487217/
  77. www.sciencedirect.com www.sciencedirect.com
    LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer
    1
    1. scibot 02 Aug 2021
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.cell.2017.12.026

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    sciencedirect.com/science/article/pii/S0092867417315064
  78. cancerres.aacrjournals.org cancerres.aacrjournals.org
    CCL27/CCL28–CCR10 Chemokine Signaling Mediates Migration of Lymphatic Endothelial Cells
    1
    1. scibot 01 Aug 2021
      RRID:IMSR_JAX:001303

      DOI: 10.1158/0008-5472.CAN-18-1858

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    cancerres.aacrjournals.org/content/79/7/1558
  79. www.sciencedirect.com www.sciencedirect.com
    Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing
    1
    1. scibot 01 Aug 2021
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.celrep.2019.08.060

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    sciencedirect.com/science/article/pii/S2211124719311088
  80. Jul 2021
  81. www.sciencedirect.com www.sciencedirect.com
    Skeletal Stem Cell-Schwann Cell Circuitry in Mandibular Repair
    1
    1. scibot 30 Jul 2021
      NOD.CB17-Prkdcscid/J

      DOI: 10.1016/j.celrep.2019.08.021

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    sciencedirect.com/science/article/pii/S221112471931054X
  82. www.sciencedirect.com www.sciencedirect.com
    p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas
    1
    1. scibot 29 Jul 2021
      Mouse strain: NOD/SCID; NOD.CB17-Prkdcscid/J

      DOI: 10.1016/j.celrep.2019.07.027

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    sciencedirect.com/science/article/pii/S2211124719309246
  83. www.sciencedirect.com www.sciencedirect.com
    Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis
    1
    1. scibot 28 Jul 2021
      SCID mouse

      DOI: 10.1016/j.ccell.2019.05.002

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    sciencedirect.com/science/article/pii/S1535610819302405
  84. www.sciencedirect.com www.sciencedirect.com
    KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism
    1
    1. scibot 27 Jul 2021
      001303

      DOI: 10.1016/j.ccell.2018.10.001

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    sciencedirect.com/science/article/pii/S1535610818304677
  85. www.sciencedirect.com www.sciencedirect.com
    Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing
    1
    1. scibot 27 Jul 2021
      RRID:IMSUR_JAX:001303

      DOI: 10.1016/j.celrep.2019.08.060

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    sciencedirect.com/science/article/pii/S2211124719311088
  86. www.sciencedirect.com www.sciencedirect.com
    Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain
    2
    1. scibot 27 Jul 2021
      IMSR_JAX:001303

      DOI: 10.1016/j.neuron.2017.02.001

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      IMSR_JAX:001303

      DOI: 10.1016/j.neuron.2017.02.001

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    sciencedirect.com/science/article/pii/S0896627317300582
  87. www.sciencedirect.com www.sciencedirect.com
    IL-23/IL-17A/TRPV1 axis produces mechanical pain via macrophage-sensory neuron crosstalk in female mice
    1
    1. scibot 21 Jul 2021
      JAX:001303

      DOI: 10.1016/j.neuron.2021.06.015

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    sciencedirect.com/science/article/pii/S0896627321004566
  88. Jun 2021
  89. www.sciencedirect.com www.sciencedirect.com
    Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states
    1
    1. scibot 12 Jun 2021
      001303

      DOI: 10.1016/j.ccell.2021.05.005

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    sciencedirect.com/science/article/pii/S1535610821002713
  90. May 2021
  91. www.sciencedirect.com www.sciencedirect.com
    Viral infection of the ovaries compromises pregnancy and reveals innate immune mechanisms protecting fertility
    1
    1. scibot 20 May 2021
      Stock No: 001303

      DOI: 10.1016/j.immuni.2021.04.020

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    sciencedirect.com/science/article/pii/S1074761321001825
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic and prognostic implications of NOTCH and MAPK signaling in bladder cancer
    1
    1. scibot 12 May 2021
      RRID:IMSR_JAX:001303

      DOI: 10.1111/cas.14878

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    ncbi.nlm.nih.gov/pmc/articles/PMC8088911/
  93. www.sciencedirect.com www.sciencedirect.com
    Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption
    1
    1. scibot 09 May 2021
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.stem.2020.12.017

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    sciencedirect.com/science/article/pii/S1934590920306019
  94. www.sciencedirect.com www.sciencedirect.com
    Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal
    1
    1. scibot 09 May 2021
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.stem.2020.04.010

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    sciencedirect.com/science/article/pii/S1934590920301491
  95. Apr 2021
  96. www.sciencedirect.com www.sciencedirect.com
    Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability
    1
    1. scibot 30 Apr 2021
      Stock#: 001303

      DOI: 10.1016/j.cmet.2020.12.002

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    sciencedirect.com/science/article/pii/S1550413120306574
  97. www.sciencedirect.com www.sciencedirect.com
    The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development
    1
    1. scibot 29 Apr 2021
      JAX- 001303

      DOI: 10.1016/j.cmet.2020.05.008

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    sciencedirect.com/science/article/pii/S1550413120302473
  98. www.sciencedirect.com www.sciencedirect.com
    Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells
    1
    1. scibot 29 Apr 2021
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.stem.2021.03.005

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    sciencedirect.com/science/article/pii/S1934590921001119
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low expression of the PPARγ-regulated gene thioredoxin-interacting protein accompanies human melanoma progression and promotes experimental lung metastases
    2
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      RRID:IMSR_JA:001303

      DOI: 10.1038/s41598-021-86329-5

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      JAX:001303

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    ncbi.nlm.nih.gov/pmc/articles/PMC8042115/
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    PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis
    1
    1. scibot 12 Apr 2021
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.molcel.2021.02.001

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    sciencedirect.com/science/article/pii/S1097276521000873
  101. Mar 2021
  102. www.sciencedirect.com www.sciencedirect.com
    Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma
    1
    1. scibot 17 Mar 2021
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.celrep.2021.108870

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    sciencedirect.com/science/article/pii/S2211124721001844
  103. www.sciencedirect.com www.sciencedirect.com
    Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity
    1
    1. scibot 10 Mar 2021
      RRID:IMSR_Jax:001303

      DOI: 10.1016/j.celrep.2021.108833

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    sciencedirect.com/science/article/pii/S2211124721001479
  104. www.sciencedirect.com www.sciencedirect.com
    Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy
    1
    1. scibot 01 Mar 2021
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.cell.2020.11.018

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    sciencedirect.com/science/article/pii/S009286742031535X
  105. Feb 2021
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis
    1
    1. scibot 26 Feb 2021
      RRID:IMSR_JAX:001303

      DOI: 10.7554/eLife.54166

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  107. www.cell.com www.cell.com
    Single-cell resolved imaging reveals intra-tumor heterogeneity in glycolysis, transitions between metabolic states, and their regulatory mechanisms
    1
    1. scibot 24 Feb 2021
      Stock No: 001303

      DOI: 10.1016/j.celrep.2021.108750

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    cell.com/cell-reports/fulltext/S2211-1247(21)00063-2
  108. www.sciencedirect.com www.sciencedirect.com
    Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients
    1
    1. scibot 24 Feb 2021
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.xcrm.2021.100202

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    sciencedirect.com/science/article/pii/S2666379121000136
  109. Jan 2021
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD117/c-kit defines a prostate CSC-like subpopulation driving progression and TKI resistance
    1
    1. scibot 20 Jan 2021
      RRID:IMSR_JAX:001303

      DOI: 10.1038/s41598-021-81126-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC7809150/
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging
    1
    1. scibot 17 Jan 2021
      RRID:IMSR_JAX:001303

      DOI: 10.7554/eLife.55117

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    ncbi.nlm.nih.gov/pmc/articles/PMC7800378/
  112. Dec 2020
  113. www.cell.com www.cell.com
    Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase ε
    1
    1. scibot 10 Dec 2020
      NOD.CB17-Prkdcscid/J

      DOI: 10.1016/j.molcel.2020.10.016

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    cell.com/molecular-cell/fulltext/S1097-2765(20)30723-1
  114. Oct 2020
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysosomal protein surface expression discriminates fat- from bone-forming human mesenchymal precursor cells
    1
    1. scibot 24 Oct 2020
      RRID:IMSR_JAX:001303

      DOI: 10.7554/eLife.58990

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    ncbi.nlm.nih.gov/pmc/articles/PMC7550188/
  116. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment
    1
    1. scibot 08 Oct 2020
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.celrep.2020.108221

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    pubmed.ncbi.nlm.nih.gov/33027668/
  117. Sep 2020
  118. cancerres.aacrjournals.org cancerres.aacrjournals.org
    A Novel Bioengineered MicroRNA-127 Prodrug Suppresses The Growth And Metastatic Potential Of Triple Negative Breast Cancer Cells
    1
    1. scibot 16 Sep 2020
      RRID:IMSR_JAX:001303

      DOI: 10.1158/0008-5472.CAN-19-0656

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    cancerres.aacrjournals.org/content/80/3/418
  119. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Proteomic profiling of the ECM of xenograft breast cancer metastases in different organs reveals distinct metastatic niches
    1
    1. scibot 12 Sep 2020
      RRID:IMSR_JAX:001303

      DOI: 10.1158/0008-5472.CAN-19-2961

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    cancerres.aacrjournals.org/content/80/7/1475
  120. www.sciencedirect.com www.sciencedirect.com
    Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module
    1
    1. scibot 06 Sep 2020
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.celrep.2020.01.024

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    sciencedirect.com/science/article/pii/S2211124720300334
  121. www.sciencedirect.com www.sciencedirect.com
    Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch
    1
    1. scibot 04 Sep 2020
      Jackson LabsStrain Code: 001303

      DOI: 10.1016/j.celrep.2020.03.036

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    sciencedirect.com/science/article/pii/S2211124720303508
  122. elifesciences.org elifesciences.org
    HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties
    1
    1. scibot 04 Sep 2020
      RRID: IMSR_JAX:001303

      DOI: 10.7554/eLife.33947

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    elifesciences.org/articles/33947
  123. www.sciencedirect.com www.sciencedirect.com
    A Modular Differentiation System Maps Multiple Human Kidney Lineages from Pluripotent Stem Cells
    1
    1. scibot 03 Sep 2020
      Jackson Laboratory: Stock No: 001303

      DOI: 10.1016/j.celrep.2020.03.040

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    sciencedirect.com/science/article/pii/S2211124720303545
  124. Jan 2020
  125. www.sciencedirect.com www.sciencedirect.com
    Combining the Allosteric Inhibitor Asciminib with Ponatinib Suppresses Emergence of and Restores Efficacy against Highly Resistant BCR-ABL1 Mutants
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.ccell.2019.08.004

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    sciencedirect.com/science/article/pii/S1535610819303721
  126. www.sciencedirect.com www.sciencedirect.com
    Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.celrep.2019.08.060

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    sciencedirect.com/science/article/pii/S2211124719311088
  127. www.sciencedirect.com www.sciencedirect.com
    The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.celrep.2019.07.107

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    sciencedirect.com/science/article/pii/S221112471931023X
  128. www.sciencedirect.com www.sciencedirect.com
    Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.molcel.2019.08.021

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    sciencedirect.com/science/article/pii/S1097276519306604
  129. www.sciencedirect.com www.sciencedirect.com
    Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.celrep.2019.07.092

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    sciencedirect.com/science/article/pii/S2211124719310083
  130. www.sciencedirect.com www.sciencedirect.com
    RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.chembiol.2019.12.005

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    sciencedirect.com/science/article/pii/S2451945619304015
  131. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:001303

      DOI: 10.1016/j.celrep.2018.12.089

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    sciencedirect.com/science/article/pii/S2211124718320497
  132. Nov 2018
  133. www.sciencedirect.com www.sciencedirect.com
    Sox9-Meis1 Inactivation Is Required for Adipogenesis, Advancing Pref-1+ to PDGFRα+ Cells
    1
    1. scibot 05 Nov 2018
      001303

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S2211124718315572
  134. www.sciencedirect.com www.sciencedirect.com
    An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:001303

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0092867418310298
  135. www.sciencedirect.com www.sciencedirect.com
    Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:001303

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1535610818303672
  136. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia
    1
    1. scibot 05 Nov 2018
      001303

      Curator: @patriciaelyse_

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    sciencedirect.com/science/article/pii/S0092867416311540
  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 05 Nov 2018
      JAX:001303

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC6122955/
  138. www.sciencedirect.com www.sciencedirect.com
    Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
    1
    1. scibot 05 Nov 2018
      001303

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276518305999
  139. www.sciencedirect.com www.sciencedirect.com
    miRNA-711 Binds and Activates TRPA1 Extracellularly to Evoke Acute and Chronic Pruritus
    1
    1. scibot 05 Nov 2018
      JAX:001303

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    sciencedirect.com/science/article/pii/S089662731830535X
  140. www.sciencedirect.com www.sciencedirect.com
    Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors
    1
    1. scibot 05 Nov 2018
      001303

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1535610818302265
  141. www.sciencedirect.com www.sciencedirect.com
    Twist1 Activation in Muscle Progenitor Cells Causes Muscle Loss Akin to Cancer Cachexia
    1
    1. scibot 05 Nov 2018
      001303

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1534580718304192
  142. www.sciencedirect.com www.sciencedirect.com
    High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:001303

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    sciencedirect.com/science/article/pii/S1934590918302169
  143. www.sciencedirect.com www.sciencedirect.com
    A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:001303

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    sciencedirect.com/science/article/pii/S1535610818301259
  144. europepmc.org europepmc.org
    Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth.
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:001303

      Curator: @evieth

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    europepmc.org/articles/PMC5736349/
  145. Nov 2017
  146. www.sciencedirect.com www.sciencedirect.com
    Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells
    1
    1. scibot 08 Nov 2017
      RRID: IMSR_JAX: 001303

      Curator: @BlakeMcMurray

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    sciencedirect.com/science/article/pii/S0092867416310832
  147. elifesciences.org elifesciences.org
    Replication Study: Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
    1
    1. scibot 08 Nov 2017
      IMSR_JAX:001303

      Curator: @chewbeccax

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    elifesciences.org/articles/25306
  148. elifesciences.org elifesciences.org
    Registered report: the microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
    1
    1. scibot 08 Nov 2017
      NOD/SCID mice

      Curator: @jcabotaj

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    elifesciences.org/content/4/e06434
  149. elifesciences.org elifesciences.org
    Registered report: Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukemia
    1
    1. scibot 08 Nov 2017
      NOD-SCID mice

      Curator: @jcabotaj

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    elifesciences.org/content/4/e08997