69 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fibrotic remodeling in the NOD/ShiLtJ mouse model of Sjögren’s disease: insights from single-cell transcriptomics and AI-driven ECM quantification
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    pmc.ncbi.nlm.nih.gov/articles/PMC13429612/
  3. Jul 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Both soluble and cell surface CD137 expressed by Foxp3+ CD4 T cells restrain autoimmune diabetes
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    pmc.ncbi.nlm.nih.gov/articles/PMC13340443/
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    LEF1 and niche factors determine T cell stemness across chronic diseases
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    sciencedirect.com/science/article/pii/S0092867426007099
  6. Jun 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Beta cell microRNAs function as molecular hubs of type 1 diabetes pathogenesis and as biomarkers of diabetes risk
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    pmc.ncbi.nlm.nih.gov/articles/PMC13236762/
  8. May 2026
  9. www.science.org www.science.org
    Real-time in vivo analysis of murine β cells reveals autophagic flux defects before onset of autoimmune diabetes
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    science.org/doi/10.1126/scitranslmed.adj4902
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    Longitudinal analysis of body weight reveals homeostatic and adaptive traits linked to lifespan in diversity outbred mice
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    nature.com/articles/s41467-026-68392-6
  11. Mar 2026
  12. www.biorxiv.org www.biorxiv.org
    Synthetic Immunological Niche Reveals Early Immune Dysregulation and Stratifies Therapeutic Response in Type 1 Diabetes
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    biorxiv.org/content/10.64898/2026.03.06.710219v1
  13. Feb 2026
  14. www.sciencedirect.com www.sciencedirect.com
    Tet2 modulates ER stress responses related to β-cell death and autoimmunity in diabetes
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    sciencedirect.com/science/article/pii/S2589004226001938
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    Messenger RNA delivery to islet β cells using conjugated lipid nanoparticles
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    sciencedirect.com/science/article/pii/S2666379126000510
  16. Oct 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A tandem repeat atlas for the genome of inbred mouse strains: A genetic variation resource
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    pmc.ncbi.nlm.nih.gov/articles/PMC12552916/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Hippo terminal effector YAP boosts enterovirus replication in type 1 diabetes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12500894/
  19. Sep 2025
  20. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225017985-main-html.html
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    52.53.155.43/bfa103a56e03ca8260532bade686a824030c14b2/1-s2.0-S2589004225017985-main-html.html
  21. Aug 2025
  22. www.sciencedirect.com www.sciencedirect.com
    A vascular-associated fibroblastic cell controls pancreatic islet immunity
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    sciencedirect.com/science/article/pii/S221112472500960X
  23. Jul 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sex and Genotype Affect Mouse Hippocampal Gene Expression in Response to Blast-Induced Traumatic Brain Injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC12289863/
  25. May 2025
  26. www.sciencedirect.com www.sciencedirect.com
    Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice
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    sciencedirect.com/science/article/pii/S2352396425001781
  27. Feb 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-Yield Generation of Glucose-Responsive Pseudoislets From Murine Insulinoma Cells for In Vitro Studies and Longitudinal Monitoring of Graft Survival In Vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC11780636/
  29. Dec 2024
  30. link.springer.com link.springer.com
    Inhibition of CD226 co-stimulation suppresses diabetes development in the NOD mouse by augmenting regulatory T cells and diminishing effector T cell function
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    link.springer.com/article/10.1007/s00125-024-06329-8
  31. Oct 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes β-Cell IGF-I Signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10545554/
  33. Aug 2024
  34. www.sciencedirect.com www.sciencedirect.com
    CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes
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    sciencedirect.com/science/article/pii/S107476132400373X
  35. Jul 2024
  36. www.biorxiv.org www.biorxiv.org
    Inhibition of CD226 Co-Stimulation Suppresses Diabetes Development in the NOD Mouse by Augmenting Tregs and Diminishing Effector T Cell Function
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    biorxiv.org/content/10.1101/2024.07.16.603756v1
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmaceutical targeting of the cannabinoid type 1 receptor impacts the crosstalk between immune cells and islets to reduce insulitis in humans
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    ncbi.nlm.nih.gov/pmc/articles/PMC11410908/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular profiling of NOD mouse islets reveals a novel regulator of insulitis onset
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    ncbi.nlm.nih.gov/pmc/articles/PMC11199597/
  39. Jun 2024
  40. www.sciencedirect.com www.sciencedirect.com
    Islet cell stress induced by insulin-degrading enzyme deficiency promotes regeneration and protection from autoimmune diabetes
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    sciencedirect.com/science/article/pii/S2589004224011519
  41. www.sciencedirect.com www.sciencedirect.com
    Quantitative trait loci mapping provides insights into the genetic regulation of dendritic cell numbers in mouse tissues
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    sciencedirect.com/science/article/pii/S2211124724006247
  42. May 2024
  43. www.sciencedirect.com www.sciencedirect.com
    CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8+ T cells in diabetic autoimmunity
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    sciencedirect.com/science/article/pii/S107476132400222X
  44. Jan 2024
  45. 52.53.155.43 52.53.155.43
    Discordant effects of polyamine depletion by DENSpm and DFMO on β cell cytokine stress and diabetes outcomes in mice
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    52.53.155.43/2d936eff3de62abd14c31ac4678d07f195bdd41e/bqae001-html.html
  46. Oct 2023
  47. www.biorxiv.org www.biorxiv.org
    Palatal segment contributions to midfacial growth in three inbred mouse strains
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    biorxiv.org/content/10.1101/2023.10.03.560703v1
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel regulators of islet function identified from genetic variation in mouse islet Ca2+ oscillations
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    ncbi.nlm.nih.gov/pmc/articles/PMC10547476/
  49. Sep 2023
  50. link.springer.com link.springer.com
    59 th EASD Annual Meeting of the European Association for the Study of Diabetes
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    link.springer.com/article/10.1007/s00125-023-05969-6
  51. Jul 2023
  52. www.sciencedirect.com www.sciencedirect.com
    Genetic pathways regulating the longitudinal acquisition of cocaine self-administration in a panel of inbred and recombinant inbred mice
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    sciencedirect.com/science/article/pii/S2211124723008677
  53. Jun 2023
  54. www.biorxiv.org www.biorxiv.org
    Real Time In vivo Analysis of Pancreatic Beta-cell Autophagic Flux Reveals Impairment Before Onset of Autoimmune Diabetes
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    biorxiv.org/content/10.1101/2023.05.23.541935v1
  55. May 2023
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elements
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    ncbi.nlm.nih.gov/pmc/articles/PMC10203049/
  57. Feb 2023
  58. www.sciencedirect.com www.sciencedirect.com
    DRAK2 contributes to type 1 diabetes by negatively regulating IL-2 sensitivity to alter regulatory T cell development
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    sciencedirect.com/science/article/pii/S2211124723001171
  59. Jan 2023
  60. www.sciencedirect.com www.sciencedirect.com
    Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes
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    sciencedirect.com/science/article/pii/S1931312822006102
  61. Nov 2022
  62. www.sciencedirect.com www.sciencedirect.com
    Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection
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    sciencedirect.com/science/article/pii/S2211124722013286
  63. Jun 2022
  64. www.sciencedirect.com www.sciencedirect.com
    Proinflammatory signaling in islet β cells propagates invasion of pathogenic immune cells in autoimmune diabetes
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    sciencedirect.com/science/article/pii/S2211124722008002
  65. www.sciencedirect.com www.sciencedirect.com
    Genetic background and sex control the outcome of high-fat diet feeding in mice
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    sciencedirect.com/science/article/pii/S2589004222007398
  66. www.sciencedirect.com www.sciencedirect.com
    Glucagon-receptor-antagonism-mediated β-cell regeneration as an effective anti-diabetic therapy
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    sciencedirect.com/science/article/pii/S2211124722006477
  67. Mar 2022
  68. www.sciencedirect.com www.sciencedirect.com
    Induction of broadly reactive influenza antibodies increases susceptibility to autoimmunity
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    sciencedirect.com/science/article/pii/S2211124722002157
  69. Jan 2022
  70. diabetesjournals.org diabetesjournals.org
    Syntaxin 4 enrichment in β-cells prevents conversion to autoimmune diabetes in non-obese diabetic (NOD) mice
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    diabetesjournals.org/diabetes/article/70/12/2837/139076/Syntaxin-4-Enrichment-in-Cells-Prevents-Conversion
  71. www.sciencedirect.com www.sciencedirect.com
    Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation
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    sciencedirect.com/science/article/pii/S221112472101740X
  72. Oct 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation
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    sciencedirect.com/science/article/pii/S1534580721007668
  74. Sep 2021
  75. www.sciencedirect.com www.sciencedirect.com
    Regulation of protein abundance in genetically diverse mouse populations
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    sciencedirect.com/science/article/pii/S2666979X21000033
  76. Aug 2021
  77. dom-pubs.onlinelibrary.wiley.com dom-pubs.onlinelibrary.wiley.com
    High fat diet prevents the development of autoimmune diabetes in NOD mice
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    dom-pubs.onlinelibrary.wiley.com/doi/10.1111/dom.14486
  78. academic.oup.com academic.oup.com
    Exocytosis Protein DOC2B as a Biomarker of Type 1 Diabetes
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    academic.oup.com/jcem/article/103/5/1966/4916911
  79. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    Soluble Antigen Arrays Efficiently Deliver Peptides and Arrest Spontaneous Autoimmune Diabetes
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    diabetes.diabetesjournals.org/content/70/6/1334
  80. Jul 2021
  81. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention
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    sciencedirect.com/science/article/pii/S1550413119306709
  82. link.springer.com link.springer.com
    Phenotypic alterations in pancreatic lymph node stromal cells from human donors with type 1 diabetes and NOD mice
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    link.springer.com/article/10.1007/s00125-019-04984-w
  83. academic.oup.com academic.oup.com
    Exocytosis Protein DOC2B as a Biomarker of Type 1 Diabetes
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    academic.oup.com/jcem/article/103/5/1966/4916911
  84. www.sciencedirect.com www.sciencedirect.com
    Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes
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    sciencedirect.com/science/article/pii/S155041311930021X
  85. www.sciencedirect.com www.sciencedirect.com
    Maternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice
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    sciencedirect.com/science/article/pii/S1931312821002961
  86. May 2021
  87. www.sciencedirect.com www.sciencedirect.com
    NLRP1 acts as a negative regulator of Th17 cell programming in mice and humans with autoimmune diabetes
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    sciencedirect.com/science/article/pii/S2211124721005210
  88. www.sciencedirect.com www.sciencedirect.com
    RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
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    sciencedirect.com/science/article/pii/S2211124721004460
  89. www.sciencedirect.com www.sciencedirect.com
    Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency
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    sciencedirect.com/science/article/pii/S193459092030343X
  90. Apr 2021
  91. www.sciencedirect.com www.sciencedirect.com
    Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP
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    sciencedirect.com/science/article/pii/S2211124721002333
  92. Feb 2021
  93. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15058
  94. www.sciencedirect.com www.sciencedirect.com
    Dynamic Interstitial Cell Response during Myocardial Infarction Predicts Resilience to Rupture in Genetically Diverse Mice
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    sciencedirect.com/science/article/pii/S2211124720301625
  95. Jan 2021
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic and stochastic influences upon tumor formation and tumor types in Li-Fraumeni mouse models
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    ncbi.nlm.nih.gov/pmc/articles/PMC7772779/
  97. Oct 2020
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD226 Deletion Reduces Type 1 Diabetes in the NOD Mouse by Impairing Thymocyte Development and Peripheral T Cell Activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7500101/
  99. Sep 2020
  100. www.sciencedirect.com www.sciencedirect.com
    Genetic Variation in Type 1 Diabetes Reconfigures the 3D Chromatin Organization of T Cells and Alters Gene Expression
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    sciencedirect.com/science/article/pii/S1074761320300303
  101. www.sciencedirect.com www.sciencedirect.com
    An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint
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    sciencedirect.com/science/article/pii/S0092867420304931
  102. www.sciencedirect.com www.sciencedirect.com
    Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch
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    sciencedirect.com/science/article/pii/S2211124720303508
  103. Jan 2020
  104. www.sciencedirect.com www.sciencedirect.com
    Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation
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    sciencedirect.com/science/article/pii/S2211124719314810
  105. Nov 2018
  106. www.sciencedirect.com www.sciencedirect.com
    Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development
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    sciencedirect.com/science/article/pii/S155041311830576X
  107. www.sciencedirect.com www.sciencedirect.com
    Gut Microbiota-Stimulated Innate Lymphoid Cells Support β-Defensin 14 Expression in Pancreatic Endocrine Cells, Preventing Autoimmune Diabetes
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    sciencedirect.com/science/article/pii/S1550413118303942
  108. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome
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    sciencedirect.com/science/article/pii/S2451945617304622
  109. onlinelibrary.wiley.com onlinelibrary.wiley.com
    “Epigenetic control of early neurodegenerative events in Diabetic Retinopathy by the histone deacetylase SIRT6”
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14243/full
  110. www.sciencedirect.com www.sciencedirect.com
    Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease
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    sciencedirect.com/science/article/pii/S0092867417314319
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC5728720/