133 Matching Annotations
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    PI5P4Kα promotes glucose and iron acquisition to support metabolic fitness in pancreatic cancer
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  3. Aug 2025
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    NRCAM variant defined by microexon skipping is a targetable cell surface proteoform in high-grade gliomas
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  5. Jul 2025
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    RIT1 Drives Oncogenic Transformation and is an Actionable Target in Lung Adenocarcinoma
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    Preadipocyte-induced upregulation of IGFBP5 enhances ovarian cancer tumorigenesis via CREB signaling
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    Low-dose radiotherapy enhances the efficacy of PD-L1 blockade and induces the abscopal effect
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    Innovative Method for Fully Automated, Enzyme-Free Tissue Dissociation and Preparation for Single-Cell Analysis
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    High fructose promotes MYCN-amplified neuroblastoma progression through NgBR-ACSS2-mediated biosynthesis of acetyl-CoA
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  12. Jun 2025
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    Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancer
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    PLK1-mediated PDHA1 phosphorylation drives mitochondrial dysfunction, mitophagy, and cancer progression in Cr(VI)-associated lung cancer
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    Exosomal encapsulation of a steviol derivative SD9 to overcome TRAIL resistance as a highly effective therapy against lung cancer
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    In vivo CRISPR activation screen identifies acyl-CoA–binding protein as a driver of bone metastasis
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  18. May 2025
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    Bacteroides fragilis promotes chemoresistance in colorectal cancer, and its elimination by phage VA7 restores chemosensitivity
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    HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity
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  22. Apr 2025
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    The kinase PLK1 promotes Hedgehog signaling–dependent resistance to the antiandrogen enzalutamide in metastatic prostate cancer
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    Radiotherapy promotes cuproptosis and synergizes with cuproptosis inducers to overcome tumor radioresistance
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    Tumor-derived arachidonic acid reprograms neutrophils to promote immune suppression and therapy resistance in triple-negative breast cancer
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  30. Jan 2025
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    Therapeutic Targeting and Structural Characterization of a Sotorasib-Modified KRAS G12C–MHC I Complex Demonstrate the Antitumor Efficacy of Hapten-Based Strategies
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  32. Dec 2024
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    The histone H3.3 K27M mutation suppresses Ser31phosphorylation and mitotic fidelity, which can directly drive gliomagenesis
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    The Capicua C1 Domain Is Required for Full Activity of the CIC::DUX4 Fusion Oncoprotein
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  38. Oct 2024
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    Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer
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  44. Aug 2024
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  51. Jul 2024
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  55. Jun 2024
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    The Capicua C1 Domain is Required for Full Activity of the CIC::DUX4 Fusion Oncoprotein
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  59. May 2024
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  66. Apr 2024
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  68. Mar 2024
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  71. Feb 2024
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  76. Dec 2023
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  78. Nov 2023
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    Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer
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  81. Oct 2023
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  83. Sep 2023
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  87. Aug 2023
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    Discovery of oncogenic ROS1 missense mutations with sensitivity to tyrosine kinase inhibitors
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  90. Jul 2023
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  92. Jun 2023
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    USP10 regulates ZEB1 ubiquitination and protein stability to inhibit ZEB1-mediated colorectal cancer metastasis
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    5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling
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  99. Apr 2023
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    Engineering GliaTrap: a biodegradable non-swelling hydrogel with tuned release of CXCL12 to attract migrating glioblastoma cells
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    A kinome-wide CRISPR screen identifies CK1α as a target to overcome enzalutamide resistance of prostate cancer
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  103. Mar 2023
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sustained oncogenic signaling in the cytostatic state enables targeting of non-proliferating persistent cancer cells
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  105. Jan 2023
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    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma
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    Spatial transcriptomic analysis of ovarian cancer precursors reveals reactivation of IGFBP2 during pathogenesis
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  108. Dec 2022
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1
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  110. Oct 2022
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    Capicua suppresses YAP1 to limit tumorigenesis and maintain drug sensitivity in human cancer
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  112. Aug 2022
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ARID1A-deficient bladder cancer is dependent on PI3K signaling and sensitive to EZH2 and PI3K inhibitors
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  119. Jul 2022
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  126. May 2022
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  128. Apr 2022
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  135. Dec 2021
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  139. Sep 2021
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  154. Apr 2021
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  171. Jan 2020
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  175. Nov 2018
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  178. Nov 2017
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