Hypothesis

32 Matching Annotations

Jun 2025
www.sciencedirect.com www.sciencedirect.com

ILC3s sense gut microbiota through STING to initiate immune tolerance

1
1. scibot 17 Jun 2025
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1016/j.immuni.2025.05.016
  
  Resource: RRID:IMSR_JAX:002251
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S1074761325002377
May 2025
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Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway

1
1. scibot 31 May 2025
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1016/j.chom.2025.05.007
  
  Resource: RRID:IMSR_JAX:002251
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S1931312825001866
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IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis

1
1. scibot 17 May 2025
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1016/j.immuni.2025.04.004
  
  Resource: RRID:IMSR_JAX:002251
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S1074761325001670
Mar 2025
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Immunoglobulin A controls intestinal virus colonization to preserve immune homeostasis

1
1. scibot 28 Mar 2025
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1016/j.chom.2025.03.004
  
  Resource: RRID:IMSR_JAX:002251
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S1931312825000873
Jan 2025
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Neutrophil extracellular traps promote pre-metastatic niche formation in the omentum by expanding innate-like B cells that express IL-10

1
1. scibot 03 Jan 2025
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1016/j.ccell.2024.12.004
  
  Resource: RRID:IMSR_JAX:002251
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S1535610824004793
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Il10 deficiency re-balances innate immunity to mitigate Alzheimer-like pathology

1
1. scibot 22 Nov 2024
  
  in Public
  
  002251
  
  DOI: 10.1016/j.neuron.2014.12.068
  
  Resource: RRID:IMSR_JAX:002251
  
  Curator: @AleksanderDrozdz
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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pmc.ncbi.nlm.nih.gov/articles/PMC4352138/
Mar 2024
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Maternal inflammation regulates fetal emergency myelopoiesis

2
1. scibot 01 Mar 2024
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1016/j.cell.2024.02.002
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
2. scibot 01 Mar 2024
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1016/j.cell.2024.02.002
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S0092867424001235
Dec 2023
52.53.155.43 52.53.155.43

qiad158-html.html

1
1. scibot 17 Dec 2023
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1093/jleuko/qiad158
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
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52.53.155.43/42c899beea5620e593ae66892ac4a4239bf226aa/qiad158-html.html
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Colitis-induced upregulation of tumor necrosis factor receptor-2 (TNFR2) terminates epithelial regenerative signaling to restore homeostasis

1
1. scibot 23 Sep 2023
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1016/j.isci.2023.107829
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
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ncbi.nlm.nih.gov/pmc/articles/PMC10510063/
Aug 2023
www.sciencedirect.com www.sciencedirect.com

Wound-healing plasticity enables clonal expansion of founder progenitor cells in colitis

1
1. scibot 31 Aug 2023
  
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  RRID:IMSR_JAX:002251
  
  DOI: 10.1016/j.devcel.2023.08.011
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S1534580723004070
Jul 2023
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TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation

1
1. scibot 01 Jul 2023
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1016/j.immuni.2023.06.007
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S1074761323002649
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Adventitial macrophage accumulation impairs perivascular nerve function in mesenteric arteries with inflammatory bowel disease

1
1. scibot 21 Jun 2023
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.3389/fphys.2023.1198066
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
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ncbi.nlm.nih.gov/pmc/articles/PMC10278583/
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

IL-10 production by granulocytes promotes Staphylococcus aureus craniotomy infection

1
1. scibot 16 May 2023
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1186/s12974-023-02798-7
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
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ncbi.nlm.nih.gov/pmc/articles/PMC10183138/
Apr 2023
www.biorxiv.org www.biorxiv.org

Adventitial macrophage accumulation impairs perivascular nerve function in mesenteric arteries with inflammatory bowel disease

1
1. scibot 20 Apr 2023
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1101/2023.04.04.535591
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
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biorxiv.org/content/10.1101/2023.04.04.535591v1
Nov 2022
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Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy

1
1. scibot 03 Nov 2022
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1016/j.celrep.2022.111582
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S2211124722014474
May 2022
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STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program

1
1. scibot 26 May 2022
  
  in Public
  
  The Jackson LaboratoryStock No: 002251
  
  DOI: 10.1016/j.celrep.2022.110838
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S2211124722006118
Nov 2021
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Human gut bacterial metabolism drives Th17 activation and colitis

1
1. scibot 25 Nov 2021
  
  in Public
  
  Cat: 002251
  
  DOI: 10.1016/j.chom.2021.11.001
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRIDCUR:Missing RRID:IMSR_JAX:002251
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RRIDCUR:Missing

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scibot

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sciencedirect.com/science/article/pii/S1931312821005072
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Sepsis expands a CD39+ plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity

1
1. scibot 04 Sep 2021
  
  in Public
  
  Cat#002251
  
  DOI: 10.1016/j.immuni.2021.08.005
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRIDCUR:Missing RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S1074761321003356
Jul 2021
www.nature.com www.nature.com

Inhibition of inflammasome activation by a clinical strain of Klebsiella pneumoniae impairs efferocytosis and leads to bacterial dissemination

1
1. scibot 28 Jul 2021
  
  in Public
  
  JAX stock #002251
  
  DOI: 10.1038/s41419-018-1214-5
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRIDCUR:Missing RRID:IMSR_JAX:002251
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nature.com/articles/s41419-018-1214-5
Jun 2021
www.sciencedirect.com www.sciencedirect.com

Type I interferon decreases macrophage energy metabolism during mycobacterial infection

1
1. scibot 02 Jun 2021
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1016/j.celrep.2021.109195
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S2211124721005416
Apr 2021
www.sciencedirect.com www.sciencedirect.com

The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis

1
1. scibot 23 Apr 2021
  
  in Public
  
  JAX 002251
  
  DOI: 10.1016/j.cell.2020.05.048
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRIDCUR:Missing RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S0092867420306814
Mar 2021
www.sciencedirect.com www.sciencedirect.com

Interleukin-10 does not contribute to the anti-contractile nature of PVAT in health

1
1. scibot 29 Mar 2021
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1016/j.vph.2021.106838
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S1537189121000100
Feb 2021
elifesciences.org elifesciences.org

Integration of IL-2 and IL-4 signals coordinates divergent regulatory T cell responses and drives therapeutic efficacy

1
1. scibot 26 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.7554/eLife.57417
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRIDCUR:Validated RRID:IMSR_JAX:002251
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RRID:IMSR_JAX:002251

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elifesciences.org/articles/57417
Oct 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

TNF Receptor 1 Promotes Early-Life Immunity and Protects against Colitis in Mice

1
1. scibot 27 Oct 2020
  
  in Public
  
  Il10−/−
  
  DOI: 10.1016/j.celrep.2020.108275
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
  Curator comments: B6.129P2-Il10tm1Cgn/J Mus musculus IMSR Cat# JAX:002251
  
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  RRIDCUR:Missing RRID:IMSR_JAX:002251
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pubmed.ncbi.nlm.nih.gov/33086075/
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Th1-Th2 Cross-Regulation Controls Early Leishmania Infection in the Skin by Modulating the Size of the Permissive Monocytic Host Cell Reservoir

1
1. scibot 04 Sep 2020
  
  in Public
  
  The Jackson LaboratoryStrain Code #: 2251
  
  DOI: 10.1016/j.chom.2020.03.011
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S193131282030175X
www.sciencedirect.com www.sciencedirect.com

CCL2 and CXCL12 Derived from Mesenchymal Stromal Cells Cooperatively Polarize IL-10+ Tissue Macrophages to Mitigate Gut Injury

1
1. scibot 03 Sep 2020
  
  in Public
  
  Jackson LaboratoryStock No. 002251
  
  DOI: 10.1016/j.celrep.2020.01.047
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S2211124720300711
Jan 2020
www.sciencedirect.com www.sciencedirect.com

IL-10-Dependent Crosstalk between Murine Marginal Zone B Cells, Macrophages, and CD8α+ Dendritic Cells Promotes Listeria monocytogenes Infection

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  DOI: 10.1016/j.immuni.2019.05.011
  
  Resource: (IMSR Cat# JAX_002251,RRID:IMSR_JAX:002251)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
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  RRID:IMSR_JAX:002251 RRIDCUR:Validated
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RRID:IMSR_JAX:002251

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sciencedirect.com/science/article/pii/S1074761319302316
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:002251
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:002251 RRIDCUR:Validated
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RRID:IMSR_JAX:002251

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sciencedirect.com/science/article/pii/S1074761318303352
www.sciencedirect.com www.sciencedirect.com

LAG3+ Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1+ Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  Resource used:
  
  RRID:IMSR_JAX:002251
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S1074761318303273
www.sciencedirect.com www.sciencedirect.com

Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells

1
1. scibot 05 Nov 2018
  
  in Public
  
  JAX:002251
  
  Resource used:
  
  RRID:IMSR_JAX:002251
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:002251
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scibot

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sciencedirect.com/science/article/pii/S1074761318300888
www.sciencedirect.com www.sciencedirect.com

Effects of spinal non-viral interleukin-10 gene therapy formulated with d-mannose in neuropathic interleukin-10 deficient mice: Behavioral characterization, mRNA and protein analysis in pain relevant tissues

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:002251
  
  Resource used:
  
  RRID:IMSR_JAX:002251
  
  SciCrunch record: RRID:IMSR_JAX:002251
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:002251
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sciencedirect.com/science/article/pii/S0889159117305056