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Co-targeting CDK4/6 enhances anti-cancer activity and alleviates immune-related adverse events of anti-PD-1 antibody for breast cancer

1
1. scibot 01 Nov 2025
  
  in Public
  
  RRID:IMSR_JAX:002376
  
  DOI: 10.1016/j.xcrm.2025.102429
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
  What is this?
  
  RRID:IMSR_JAX:002376
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RRID:IMSR_JAX:002376

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scibot

URL

sciencedirect.com/science/article/pii/S2666379125005026
May 2025
www.sciencedirect.com www.sciencedirect.com

Sumoylated Etv1 establishes mouse mammary cancer stem cells that support tumorigenesis by non-stem cancer cells

1
1. scibot 17 May 2025
  
  in Public
  
  RRID:IMSR_JAX:002376
  
  DOI: 10.1016/j.devcel.2025.04.005
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
  What is this?
  
  RRID:IMSR_JAX:002376
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RRID:IMSR_JAX:002376

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scibot

URL

sciencedirect.com/science/article/pii/S1534580725002072
Jun 2024
www.cell.com www.cell.com

Oxygen tension-dependent variability in the cancer cell kinome impacts signaling pathways and response to targeted therapies

1
1. scibot 29 Jun 2024
  
  in Public
  
  RRID:IMSR_JAX:002376
  
  DOI: 10.1016/j.isci.2024.110068
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
  What is this?
  
  RRID:IMSR_JAX:002376
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RRID:IMSR_JAX:002376

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scibot

URL

cell.com/iscience/abstract/S2589-0042(24)01293-8
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

IRX4204 Induces Senescence and Cell Death in HER2-positive Breast Cancer and Synergizes with Anti-HER2 Therapy

1
1. scibot 07 Jun 2024
  
  in Public
  
  RRID:IMSR_JAX:002376
  
  DOI: 10.1158/1078-0432.CCR-23-3839
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
  What is this?
  
  RRID:IMSR_JAX:002376
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RRID:IMSR_JAX:002376

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11145169/
May 2024
www.nature.com www.nature.com

Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer

1
1. scibot 30 May 2024
  
  in Public
  
  RRID:IMSR_JAX:002376
  
  DOI: 10.1038/s41416-024-02697-5
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
  What is this?
  
  RRID:IMSR_JAX:002376
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RRID:IMSR_JAX:002376

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scibot

URL

nature.com/articles/s41416-024-02697-5
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Early Normal Tissue Effects and Bone Marrow Relative Biological Effectiveness for an Actinium-225-labeled HER2/neu Targeting Antibody

1
1. scibot 21 Jun 2023
  
  in Public
  
  RRID:IMSR_JAX:002376
  
  DOI: 10.1016/j.ijrobp.2023.06.003
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
  What is this?
  
  RRID:IMSR_JAX:002376
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RRID:IMSR_JAX:002376

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scibot

URL

sciencedirect.com/science/article/pii/S0360301623005862
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis

1
1. scibot 16 Nov 2022
  
  in Public
  
  002376
  
  DOI: 10.1016/j.xcrm.2022.100821
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
  What is this?
  
  RRID:IMSR_JAX:002376
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RRID:IMSR_JAX:002376

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scibot

URL

sciencedirect.com/science/article/pii/S2666379122003809
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Bone marrow Relative Biological Effectiveness (RBE) for a 212Pb-labeled anti-HER2/neu antibody

1
1. scibot 02 Aug 2022
  
  in Public
  
  RRID:IMSR_JAX:002376
  
  DOI: 10.1016/j.ijrobp.2022.07.1842
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
  What is this?
  
  RRID:IMSR_JAX:002376
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RRID:IMSR_JAX:002376

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scibot

URL

sciencedirect.com/science/article/pii/S0360301622025998
Jun 2022
aacrjournals.org aacrjournals.org

NR2F1 is a barrier to dissemination of early stage breast cancer cells.

1
1. scibot 18 Jun 2022
  
  in Public
  
  RRID:IMSR_JAX:002376
  
  DOI: 10.1158/0008-5472.CAN-21-4145
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
  What is this?
  
  RRID:IMSR_JAX:002376
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RRID:IMSR_JAX:002376

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scibot

URL

aacrjournals.org/cancerres/article/82/12/2313/699348/NR2F1-Is-a-Barrier-to-Dissemination-of-Early-Stage
rupress.org rupress.org

CD4+ T helper 2 cells suppress breast cancer by inducing terminal differentiation

1
1. scibot 07 Jun 2022
  
  in Public
  
  JAX:002376
  
  DOI: 10.1084/jem.20201963
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
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  RRID:IMSR_JAX:002376
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RRID:IMSR_JAX:002376

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scibot

URL

rupress.org/jem/article/219/7/e20201963/213261/CD4-T-helper-2-cells-suppress-breast-cancer-by
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging

1
1. scibot 21 Sep 2021
  
  in Public
  
  Stock# 002376
  
  DOI: 10.1016/j.celrep.2021.109689
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:002376
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RRIDCUR:Missing

RRID:IMSR_JAX:002376

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721011360
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Transplantation of autologous extracellular vesicles for cancer-specific targeting

1
1. scibot 19 Jul 2021
  
  in Public
  
  MGI_1930204
  
  DOI: 10.7150/thno.51344
  
  Resource: IMSR_JAX: 002376
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX: 002376
  
  Curator comments: Author used the allele ID from MGI here, the JAX id is below.
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_JAX:002376
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RRID:IMSR_JAX:002376

RRIDCUR:Unresolved

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7797692/
May 2021
www.sciencedirect.com www.sciencedirect.com

RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness

1
1. scibot 18 May 2021
  
  in Public
  
  Cat#002376
  
  DOI: 10.1016/j.devcel.2021.04.022
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:002376
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RRIDCUR:Missing

RRID:IMSR_JAX:002376

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scibot

URL

sciencedirect.com/science/article/pii/S1534580721003609
Mar 2021
www.sciencedirect.com www.sciencedirect.com

Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer

1
1. scibot 11 Mar 2021
  
  in Public
  
  Stock #: 002376
  
  DOI: 10.1016/j.celrep.2021.108822
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:002376
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RRIDCUR:Missing

RRID:IMSR_JAX:002376

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721001364
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer

1
1. scibot 26 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:002376
  
  DOI: 10.7554/eLife.58810
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
  What is this?
  
  RRID:IMSR_JAX:002376
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RRID:IMSR_JAX:002376

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7447441/
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer

1
1. scibot 01 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:002376
  
  DOI: 10.7554/eLife.58810
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
  What is this?
  
  RRID:IMSR_JAX:002376
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RRID:IMSR_JAX:002376

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7447441/
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:002376
  
  DOI: 10.1016/j.celrep.2019.08.105
  
  Resource: (IMSR Cat# JAX_002376,RRID:IMSR_JAX:002376)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:002376
  
  What is this?
  
  RRID:IMSR_JAX:002376 RRIDCUR:Validated
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RRID:IMSR_JAX:002376

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719311672