59 Matching Annotations
  1. Last 7 days
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    Astrocytes contribute to long-chain polyunsaturated fatty acid metabolism affecting microglia in fragile X syndrome
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    sciencedirect.com/science/article/pii/S2589004226035595
  3. Oct 2026
  4. www.biorxiv.org www.biorxiv.org
    Novel Co-expression of Group I Metabotropic Glutamate Receptor During Mouse Cochlear Nucleus Development
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    biorxiv.org/content/10.64898/2026.09.29.755315v1
  5. Aug 2026
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Hippocampal Astrocytes Impact Postnatal Development of Inhibitory Connections, Parvalbumin Levels, Social, and Spatial Navigation Behaviors in a Mouse Model of Fragile X Syndrome
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70541
  7. Jul 2026
  8. www.nature.com www.nature.com
    FMR1 gene therapy restores translationally relevant phenotypes in a mouse model for fragile X syndrome
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    nature.com/articles/s41434-026-00630-4
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neonatal expression of human FMRP isoform corrects cortical deficits and improves behavior in a mouse model of fragile X syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC13320503/
  10. May 2026
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Translatome profiling reveals opposing alterations in inhibitory and excitatory neurons of fragile X mice and identifies EPAC2 as a therapeutic target
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    pmc.ncbi.nlm.nih.gov/articles/PMC13242833/
  12. Apr 2026
  13. www.biorxiv.org www.biorxiv.org
    Fragile X messenger ribonucleoprotein modulates IL-6 induction and inflammatory cell death in macrophages
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    biorxiv.org/content/10.64898/2026.03.30.712626v1
  14. Jan 2026
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    Metabolic reprogramming during human neuron differentiation indicates glutaminase as a key determinant in Fragile X syndrome
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    sciencedirect.com/science/article/pii/S2211124725016298
  16. Dec 2025
  17. www.sciencedirect.com www.sciencedirect.com
    Astrocytic GABA controls fidelity of temporal cortical processing in Fragile X Syndrome
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    sciencedirect.com/science/article/pii/S0969996125004504
  18. Nov 2025
  19. 54.241.53.176 54.241.53.176
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  20. Sep 2025
  21. elifesciences.org elifesciences.org
    Scheduled feeding improves behavioral outcomes and reduces inflammation in a mouse model of fragile X syndrome
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    elifesciences.org/articles/104720
  22. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial dysfunction reveals H2S-mediated synaptic sulfhydration as a potential mechanism for autism-associated social defects
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    sciencedirect.com/science/article/pii/S1550413125003596
  23. Aug 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Conditional deletion of TRPC1 channel modulates synaptic plasticity, long term depression, and memory extinction in Fragile X Syndrome mice.
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    pmc.ncbi.nlm.nih.gov/articles/PMC12329558/
  25. elifesciences.org elifesciences.org
    Scheduled feeding improves behavioral outcomes and reduces inflammation in a mouse model of Fragile X syndrome
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    elifesciences.org/reviewed-preprints/104720
  26. Jul 2025
  27. 52.53.155.43 52.53.155.43
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  28. Jun 2025
  29. 52.53.155.43 52.53.155.43
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  30. Apr 2025
  31. www.sciencedirect.com www.sciencedirect.com
    Brain-wide mapping of immune receptors uncovers a neuromodulatory role of IL-17E and the receptor IL-17RB
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    sciencedirect.com/science/article/pii/S009286742500279X
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Early expression of GluN2A-containing NMDA receptors in a model of fragile X syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC11254340/
  33. Feb 2025
  34. www.cell.com www.cell.com
    Non-ionotropic signaling through the NMDA receptor GluN2B carboxy-terminal domain drives dendritic spine plasticity and reverses fragile X phenotypes
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    cell.com/cell-reports/fulltext/S2211-1247(25)00082-8
  35. 52.53.155.43 52.53.155.43
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  36. Dec 2024
  37. 52.53.155.43 52.53.155.43
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  39. Sep 2024
  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
    P2X7 expression patterns in the developing Fmr1-knockout mouse hippocampus
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    onlinelibrary.wiley.com/doi/10.1002/hipo.23634
  41. Jul 2024
  42. royalsocietypublishing.org royalsocietypublishing.org
    Cage effects on synaptic plasticity and its modulation in a mouse model of fragile X syndrome
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    royalsocietypublishing.org/doi/10.1098/rstb.2023.0484
  43. www.biorxiv.org www.biorxiv.org
    Sex-specific loss of mitochondrial membrane integrity and mass in the auditory brainstem of a mouse model of Fragile X syndrome
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    biorxiv.org/content/10.1101/2024.07.02.601649v1
  44. May 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parvalbumin interneuron activity in autism underlies susceptibility to PTSD-like memory formation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11089364/
  46. Apr 2024
  47. www.sciencedirect.com www.sciencedirect.com
    Distributed X chromosome inactivation in brain circuitry is associated with X-linked disease penetrance of behavior
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    sciencedirect.com/science/article/pii/S2211124724003966
  48. www.embopress.org www.embopress.org
    mGluR7 allosteric modulator AMN082 corrects protein synthesis and pathological phenotypes in FXS | EMBO Molecular Medicine
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    embopress.org/doi/full/10.1038/s44321-024-00038-w
  49. Feb 2024
  50. www.jneurosci.org www.jneurosci.org
    Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice
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    jneurosci.org/content/44/7/e1665232023
  51. Jan 2024
  52. 52.53.155.43 52.53.155.43
    JNEUROSCI.1665-23.2023.full-html.html
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Growth-suppressor microRNAs mediate synaptic overgrowth and behavioral deficits in Fragile X mental retardation protein deficiency
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    ncbi.nlm.nih.gov/pmc/articles/PMC10792201/
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FMRP regulation of aggrecan mRNA translation controls perineuronal net development
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16048
  55. Dec 2023
  56. www.sciencedirect.com www.sciencedirect.com
    Protocol for measuring protein synthesis in specific cell types in the mouse brain using in vivo non-canonical amino acid tagging
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    sciencedirect.com/science/article/pii/S2666166723007426
  57. Jul 2023
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cell-type-specific disruption of cortico-striatal circuitry drives repetitive patterns of behavior in fragile X syndrome model mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC10552611/
  59. May 2023
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC10113018/
  61. Apr 2023
  62. link.springer.com link.springer.com
    The activation of mGluR4 rescues parallel fiber synaptic transmission and LTP, motor learning and social behavior in a mouse model of Fragile X Syndrome
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    link.springer.com/article/10.1186/s13229-023-00547-4
  63. Dec 2022
  64. www.sciencedirect.com www.sciencedirect.com
    Excessive proteostasis contributes to pathology in fragile X syndrome
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    sciencedirect.com/science/article/pii/S0896627322010352
  65. Nov 2022
  66. www.sciencedirect.com www.sciencedirect.com
    Development of single-molecule ubiquitination mediated fluorescence complementation to visualize protein ubiquitination dynamics in dendrites
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    sciencedirect.com/science/article/pii/S2211124722015297
  67. Feb 2022
  68. elifesciences.org elifesciences.org
    FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons
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    elifesciences.org/articles/71892
  69. Nov 2021
  70. www.sciencedirect.com www.sciencedirect.com
    The organization and development of cortical interneuron presynaptic circuits are area specific
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    sciencedirect.com/science/article/pii/S2211124721014728
  71. Oct 2021
  72. link.springer.com link.springer.com
    Increased 2-arachidonoyl-sn-glycerol levels normalize cortical responses to sound and improve behaviors in Fmr1 KO mice
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    link.springer.com/article/10.1186/s11689-021-09394-x
  73. Aug 2021
  74. www.sciencedirect.com www.sciencedirect.com
    NGPF2 triggers synaptic scaling up through ALK-LIMK-cofilin-mediated mechanisms
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    sciencedirect.com/science/article/pii/S2211124721009451
  75. www.sciencedirect.com www.sciencedirect.com
    Normal CA1 Place Fields but Discoordinated Network Discharge in a Fmr1-Null Mouse Model of Fragile X Syndrome
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    sciencedirect.com/science/article/pii/S0896627317312114
  76. www.jneurosci.org www.jneurosci.org
    Dysregulated NMDA-Receptor Signaling Inhibits Long-Term Depression in a Mouse Model of Fragile X Syndrome
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    jneurosci.org/content/36/38/9817.full
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lovastatin, not Simvastatin, Corrects Core Phenotypes in the Fragile X Mouse Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC6565377/
  78. Jul 2021
  79. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Effects of the presence and absence of amino acids on translation, signaling and long‐term depression in hippocampal slices from Fmr1 knockout mice
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14874
  80. www.jneurosci.org www.jneurosci.org
    Dysregulated NMDA-Receptor Signaling Inhibits Long-Term Depression in a Mouse Model of Fragile X Syndrome
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    jneurosci.org/content/36/38/9817.full
  81. Mar 2021
  82. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The small GTPase Arf6 is dysregulated in a mouse model for fragile X syndrome
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15230
  83. Feb 2021
  84. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Acute pharmacological inhibition of matrix metalloproteinase‐9 activity during development restores perineuronal net formation and normalizes auditory processing in Fmr1 KO mice
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15037
  85. Dec 2020
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transient Enhanced GluA2 Expression in Young Hippocampal Neurons of a Fragile X Mouse Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC7745073/
  87. Sep 2020
  88. www.sciencedirect.com www.sciencedirect.com
    Input-Output Relationship of CA1 Pyramidal Neurons Reveals Intact Homeostatic Mechanisms in a Mouse Model of Fragile X Syndrome
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    sciencedirect.com/science/article/pii/S2211124720309736
  89. Jan 2020
  90. www.sciencedirect.com www.sciencedirect.com
    FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export
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    sciencedirect.com/science/article/pii/S2211124719308526
  91. elifesciences.org elifesciences.org
    FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory
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    elifesciences.org/articles/46919
  92. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Inhibition of GluN2A NMDA receptors ameliorates synaptic plasticity deficits in the Fmr1−/y mouse model
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    physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP276304
  93. Nov 2017
  94. www.jneurosci.org www.jneurosci.org
    Dysregulated NMDA-Receptor Signaling Inhibits Long-Term Depression in a Mouse Model of Fragile X Syndrome
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