Hypothesis

16 Matching Annotations

Jun 2025
elifesciences.org elifesciences.org

Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma

1
1. scibot 11 Jun 2025
  
  in Public
  
  Ptch1+/-
  
  DOI: 10.7554/eLife.105339.1
  
  Resource: (IMSR Cat# JAX_003081,RRID:IMSR_JAX:003081)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  What is this?
  
  RRID:IMSR_JAX:003081
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RRID:IMSR_JAX:003081

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scibot

URL

elifesciences.org/reviewed-preprints/105339v1
May 2025
www.sciencedirect.com www.sciencedirect.com

Chromatin modification abnormalities by CHD7 and KMT2C loss promote medulloblastoma progression

1
1. scibot 20 May 2025
  
  in Public
  
  The Jackson LaboratoryJAX No. 003081
  
  DOI: 10.1016/j.celrep.2025.115673
  
  Resource: (IMSR Cat# JAX_003081,RRID:IMSR_JAX:003081)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  What is this?
  
  RRID:IMSR_JAX:003081
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RRID:IMSR_JAX:003081

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scibot

URL

sciencedirect.com/science/article/pii/S2211124725004449
Jan 2025
www.sciencedirect.com www.sciencedirect.com

A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance

1
1. scibot 28 Jan 2025
  
  in Public
  
  RRID:IMSR_JAX:003081
  
  DOI: 10.1016/j.devcel.2025.01.001
  
  Resource: (IMSR Cat# JAX_003081,RRID:IMSR_JAX:003081)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  What is this?
  
  RRID:IMSR_JAX:003081
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RRID:IMSR_JAX:003081

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scibot

URL

sciencedirect.com/science/article/pii/S1534580725000012
Jun 2024
www.sciencedirect.com www.sciencedirect.com

Cancer-specific epigenome identifies oncogenic hijacking by nuclear factor I family proteins for medulloblastoma progression

1
1. scibot 04 Jun 2024
  
  in Public
  
  003081
  
  DOI: 10.1016/j.devcel.2024.05.013
  
  Resource: (IMSR Cat# JAX_003081,RRID:IMSR_JAX:003081)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  What is this?
  
  DOI:10.1016/j.devcel.2024.05.013 RRID:IMSR_JAX:003081
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RRID:IMSR_JAX:003081

DOI:10.1016/j.devcel.2024.05.013

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scibot

URL

sciencedirect.com/science/article/pii/S1534580724003307
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors

1
1. scibot 25 Jan 2023
  
  in Public
  
  RRID:IMSR_JAX:003081
  
  DOI: 10.1158/2767-9764.crc-22-0124
  
  Resource: (IMSR Cat# JAX_003081,RRID:IMSR_JAX:003081)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  What is this?
  
  RRID:IMSR_JAX:003081
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RRID:IMSR_JAX:003081

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9853917/
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hedgehog regulation of epithelial cell state and morphogenesis in the larynx

1
1. scibot 06 Dec 2022
  
  in Public
  
  RRID:IMSR_JAX:003081
  
  DOI: 10.7554/eLife.77055
  
  Resource: (IMSR Cat# JAX_003081,RRID:IMSR_JAX:003081)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  What is this?
  
  RRID:IMSR_JAX:003081
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RRID:IMSR_JAX:003081

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9718526/
Nov 2022
aacrjournals.org aacrjournals.org

A druggable UHRF1/DNMT1/GLI complex regulates Sonic hedgehog dependent tumor growth

1
1. scibot 22 Nov 2022
  
  in Public
  
  RRID:IMSR_JAX:003081
  
  DOI: 10.1158/1541-7786.MCR-22-0182
  
  Resource: (IMSR Cat# JAX_003081,RRID:IMSR_JAX:003081)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  What is this?
  
  RRID:IMSR_JAX:003081
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RRID:IMSR_JAX:003081

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scibot

URL

aacrjournals.org/mcr/article/20/11/1598/709855/A-Druggable-UHRF1-DNMT1-GLI-Complex-Regulates
Oct 2022
52.53.155.43 52.53.155.43

mcr-22-0182-html.html

1
1. scibot 29 Oct 2022
  
  in Public
  
  JAX:003081
  
  DOI: 10.1158/1541-7786.MCR-22-0182
  
  Resource: (IMSR Cat# JAX_003081,RRID:IMSR_JAX:003081)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  What is this?
  
  RRID:IMSR_JAX:003081
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RRID:IMSR_JAX:003081

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scibot

URL

52.53.155.43/736c3e45aba95f2b9e7e9af3df073f3bca899f3f/mcr-22-0182-html.html
Jun 2022
aacrjournals.org aacrjournals.org

Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors

1
1. scibot 15 Jun 2022
  
  in Public
  
  RRID:IMSR_JAX:003081
  
  DOI: 10.1158/2767-9764.CRC-22-0124
  
  Resource: (IMSR Cat# JAX_003081,RRID:IMSR_JAX:003081)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  What is this?
  
  RRID:IMSR_JAX:003081
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RRID:IMSR_JAX:003081

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scibot

URL

aacrjournals.org/cancerrescommun/article/2/6/402/699311/Cancer-Stem-Cells-not-Bulk-Tumor-Cells-Determine
Feb 2022
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development

1
1. scibot 23 Feb 2022
  
  in Public
  
  The Jackson LaboratoryStock No: 003081
  
  DOI: 10.1016/j.celrep.2022.110416
  
  Resource: (IMSR Cat# JAX_003081,RRID:IMSR_JAX:003081)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  What is this?
  
  RRID:IMSR_JAX:003081
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RRID:IMSR_JAX:003081

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scibot

URL

pubmed.ncbi.nlm.nih.gov/35196485/
Nov 2021
www.sciencedirect.com www.sciencedirect.com

Controlling tissue patterning by translational regulation of signaling transcripts through the core translation factor eIF3c

1
1. scibot 09 Nov 2021
  
  in Public
  
  JAX:003081
  
  DOI: 10.1016/j.devcel.2021.10.009
  
  Resource: (IMSR Cat# JAX_003081,RRID:IMSR_JAX:003081)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  What is this?
  
  RRID:IMSR_JAX:003081
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RRID:IMSR_JAX:003081

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scibot

URL

sciencedirect.com/science/article/pii/S1534580721008108
May 2021
www.sciencedirect.com www.sciencedirect.com

Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling

1
1. scibot 05 May 2021
  
  in Public
  
  Strain #003081
  
  DOI: 10.1016/j.devcel.2020.06.034
  
  Resource: (IMSR Cat# JAX_003081,RRID:IMSR_JAX:003081)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:003081
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RRIDCUR:Missing

RRID:IMSR_JAX:003081

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scibot

URL

sciencedirect.com/science/article/pii/S1534580720305426
Jan 2021
www.sciencedirect.com www.sciencedirect.com

Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor

1
1. scibot 27 Jan 2021
  
  in Public
  
  JAX:003081
  
  DOI: 10.1016/j.celrep.2020.03.075
  
  Resource: (IMSR Cat# JAX_003081,RRID:IMSR_JAX:003081)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  What is this?
  
  RRID:IMSR_JAX:003081 RRIDCUR:Validated
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RRID:IMSR_JAX:003081

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720304010
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth

1
1. scibot 03 Sep 2020
  
  in Public
  
  JAX#003081
  
  DOI: 10.1016/j.cell.2019.12.024
  
  Resource: (IMSR Cat# JAX_003081,RRID:IMSR_JAX:003081)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  What is this?
  
  RRID:IMSR_JAX:003081
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RRID:IMSR_JAX:003081

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scibot

URL

sciencedirect.com/science/article/pii/S0092867419313868
Nov 2018
www.sciencedirect.com www.sciencedirect.com

BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation

1
1. scibot 05 Nov 2018
  
  in Public
  
  JAX:003081
  
  Resource used:
  
  RRID:IMSR_JAX:003081
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:003081
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RRID:IMSR_JAX:003081

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scibot

URL

sciencedirect.com/science/article/pii/S1535610818302204
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis

1
1. scibot 08 Nov 2017
  
  in Public
  
  Mouse: Ptch1tm1MpsThe Jackson LaboratoryStock No: 003081
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:003081
  
  SciCrunch record: RRID:IMSR_JAX:003081
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:003081 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:003081

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867417307547