Hypothesis

16 Matching Annotations

Jul 2026
www.sciencedirect.com www.sciencedirect.com

Mitochondria-to-plasma-membrane H2O2 signaling induced by branched-chain keto acid oxidation essentially stimulates insulin secretion in pancreatic β-cells

1
1. scibot 21 Jul 2026
  
  in Public
  
  RRID:IMSR_JAX:003573
  
  DOI: 10.1016/j.redox.2026.104309
  
  Resource: (IMSR Cat# JAX_003573,RRID:IMSR_JAX:003573)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  What is this?
  
  RRID:IMSR_JAX:003573
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RRID:IMSR_JAX:003573

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scibot

URL

sciencedirect.com/science/article/pii/S2213231726003083
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Identification of a neural basis for energy expenditure in the mouse arcuate hypothalamus

1
1. scibot 18 Sep 2025
  
  in Public
  
  JAX:003573
  
  DOI: 10.1016/j.neuron.2025.08.021
  
  Resource: (IMSR Cat# JAX_003573,RRID:IMSR_JAX:003573)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  What is this?
  
  RRID:IMSR_JAX:003573
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RRID:IMSR_JAX:003573

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scibot

URL

sciencedirect.com/science/article/pii/S0896627325006300
Dec 2024
www.sciencedirect.com www.sciencedirect.com

Pancreatic β cell interleukin-22 receptor subunit alpha 1 deficiency impairs β cell function in type 2 diabetes via cytochrome b5 reductase 3

1
1. scibot 17 Dec 2024
  
  in Public
  
  Jackson Laboratory Cat_003573
  
  DOI: 10.1016/j.celrep.2024.115057
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  What is this?
  
  RRID:IMSR_JAX:003573 RRIDCUR:Unresolved
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RRID:IMSR_JAX:003573

RRIDCUR:Unresolved

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724014086
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mosaic ablation of pancreatic β cells induces de-differentiation and repetitive proliferation of residual β cells in adult mice

1
1. scibot 25 Sep 2024
  
  in Public
  
  Jackson Laboratory#003573
  
  DOI: 10.1016/j.isci.2024.110656
  
  Resource: (IMSR Cat# JAX_003573,RRID:IMSR_JAX:003573)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  What is this?
  
  RRID:IMSR_JAX:003573
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RRID:IMSR_JAX:003573

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11416228/
Mar 2024
www.sciencedirect.com www.sciencedirect.com

Cytosolic pH is a direct nexus in linking environmental cues with insulin processing and secretion in pancreatic β cells

1
1. scibot 21 Mar 2024
  
  in Public
  
  The Jackson LaboratoryCAT:003573
  
  DOI: 10.1016/j.cmet.2024.02.012
  
  Resource: (IMSR Cat# JAX_003573,RRID:IMSR_JAX:003573)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  What is this?
  
  RRID:IMSR_JAX:003573
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RRID:IMSR_JAX:003573

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scibot

URL

sciencedirect.com/science/article/pii/S1550413124000597
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

circGlis3 promotes β-cell dysfunction by inhibiting hnRNPF nuclear translocation and encoding Glis3-348aa protein

1
1. scibot 18 Jan 2024
  
  in Public
  
  JAX:003573
  
  DOI: 10.1016/j.isci.2023.108680
  
  Resource: (IMSR Cat# JAX_003573,RRID:IMSR_JAX:003573)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  What is this?
  
  RRID:IMSR_JAX:003573
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RRID:IMSR_JAX:003573

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10788204/
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Lung injury induces a polarized immune response by self-antigen-specific CD4+ Foxp3+ regulatory T cells

1
1. scibot 21 Jul 2023
  
  in Public
  
  RRID:IMSR_JAX:003573
  
  DOI: 10.1016/j.celrep.2023.112839
  
  Resource: (IMSR Cat# JAX_003573,RRID:IMSR_JAX:003573)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  What is this?
  
  RRID:IMSR_JAX:003573
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RRID:IMSR_JAX:003573

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scibot

URL

sciencedirect.com/science/article/pii/S2211124723008501
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Regional and cell-type-specific afferent and efferent projections of the mouse claustrum

1
1. scibot 17 Feb 2023
  
  in Public
  
  JAX:003573
  
  DOI: 10.1016/j.celrep.2023.112118
  
  Resource: (IMSR Cat# JAX_003573,RRID:IMSR_JAX:003573)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  What is this?
  
  RRID:IMSR_JAX:003573
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RRID:IMSR_JAX:003573

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scibot

URL

sciencedirect.com/science/article/pii/S2211124723001298
Jul 2022
www.nature.com www.nature.com

Mitoribosome insufficiency in β cells is associated with type 2 diabetes-like islet failure

1
1. scibot 12 Jul 2022
  
  in Public
  
  RRID:IMSR_JAX:003573
  
  DOI: 10.1038/s12276-022-00797-x
  
  Resource: (IMSR Cat# JAX_003573,RRID:IMSR_JAX:003573)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  What is this?
  
  RRID:IMSR_JAX:003573
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RRID:IMSR_JAX:003573

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scibot

URL

nature.com/articles/s12276-022-00797-x
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes

1
1. scibot 05 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:003573
  
  DOI: 10.1016/j.cmet.2018.04.013
  
  Resource: (IMSR Cat# JAX_003573,RRID:IMSR_JAX:003573)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  What is this?
  
  RRID:IMSR_JAX:003573
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RRID:IMSR_JAX:003573

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5989056/
Jul 2021
elifesciences.org elifesciences.org

A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary CaVβ subunits

1
1. scibot 29 Jul 2021
  
  in Public
  
  Jackson Laboratories Stock #003573
  
  DOI: 10.7554/eLife.49253
  
  Resource: (IMSR Cat# JAX_003573,RRID:IMSR_JAX:003573)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  What is this?
  
  RRID:IMSR_JAX:003573 RRIDCUR:Unrecognized
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RRID:IMSR_JAX:003573

RRIDCUR:Unrecognized

Annotators

scibot

URL

elifesciences.org/articles/49253
Feb 2021
academic.oup.com academic.oup.com

Ins1-Cre and Ins1-Cre ER gene replacement alleles are susceptible to silencing by DNA hypermethylation

1
1. scibot 24 Feb 2021
  
  in Public
  
  RRID:IMS4_JAX:003573
  
  DOI: 10.1210/endocr/bqaa054
  
  Resource: (IMSR Cat# JAX_003573,RRID:IMSR_JAX:003573)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  Curator comments: B6.Cg-Tg(Ins2-cre)25Mgn/J Mus musculus Cite this (IMSR Cat# JAX:003573
  
  What is this?
  
  RRIDCUR:Unresolved RRIDCUR:SyntaxError RRID:IMSR_JAX:003573
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RRID:IMSR_JAX:003573

RRIDCUR:SyntaxError

RRIDCUR:Unresolved

Annotators

scibot

URL

academic.oup.com/endo/article/161/8/bqaa054/5817889
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Glucose-Stimulated Insulin Secretion Fundamentally Requires H 2 O 2 Signaling by NADPH Oxidase 4

1
1. scibot 06 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:003573
  
  DOI: 10.2337/db19-1130
  
  Resource: (IMSR Cat# JAX_003573,RRID:IMSR_JAX:003573)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  What is this?
  
  RRID:IMSR_JAX:003573 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:003573

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7306122/
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:003573
  
  DOI: 10.1016/j.chembiol.2018.10.019
  
  Resource: (IMSR Cat# JAX_003573,RRID:IMSR_JAX:003573)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  What is this?
  
  RRID:IMSR_JAX:003573 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:003573

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945618303799
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:003573
  
  Curator: @evieth
  
  Resource used:
  
  RRID:IMSR_JAX:003573
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:003573 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:IMSR_JAX:003573

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5989056/
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal β Cell Proliferation

1
1. scibot 08 Nov 2017
  
  in Public
  
  IMSR_JAX:003573
  
  Curator: @chewbeccax
  
  Resource used:
  
  RRID:IMSR_JAX:003573
  
  SciCrunch record: RRID:IMSR_JAX:003573
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:003573 RRIDCUR:Validated
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Tags

RRIDCUR:Validated

RRID:IMSR_JAX:003573

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S155041311730219X