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117 Matching Annotations

Last 7 days
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Hepatic adaptation to chronic metabolic stress primes tumorigenesis

1
1. scibot 23 Dec 2025
  
  in Public
  
  Maintained in lab (originally from Jackson Laboratory)Strain #003574
  
  DOI: 10.1016/j.cell.2025.11.031
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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sciencedirect.com:5037/science/article/pii/S0092867425013662
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Post-translational switch of DHCR24 acetylation sustains sterol synthesis and promotes HCC via the 7-ketocholesterol/p62 axis

1
1. scibot 13 Dec 2025
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.celrep.2025.116640
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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sciencedirect.com:5037/science/article/pii/S2211124725014123
Nov 2025
www.sciencedirect.com www.sciencedirect.com

UDP-GlcUA triggers PKR kinase activity to promote liquid-liquid phase separation of TOP2A and enhances radioimmunotherapy resistance

1
1. scibot 18 Nov 2025
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.molcel.2025.10.011
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S1097276525008287
Oct 2025
www.science.org www.science.org

T cell cholesterol transport links intestinal immune responses to dietary lipid absorption

1
1. scibot 23 Oct 2025
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1126/science.adt4169
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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science.org/doi/10.1126/science.adt4169
www.sciencedirect.com www.sciencedirect.com

HUWE1 stimulates mTORC1 activity by enhancing Rheb interaction with mTORC1 and supports de novo pyrimidine synthesis

1
1. scibot 11 Oct 2025
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.celrep.2025.116382
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S2211124725011532
Jul 2025
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Functional liver genomics identifies hepatokines promoting wasting in cancer cachexia

1
1. scibot 22 Jul 2025
  
  in Public
  
  JAXStrain code:003574
  
  DOI: 10.1016/j.cell.2025.06.039
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S009286742500741X
www.sciencedirect.com www.sciencedirect.com

ANGPTL3 orchestrates hepatic fructose sensing and metabolism

1
1. scibot 15 Jul 2025
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.celrep.2025.115962
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S2211124725007338
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Modulation of glucocorticoid receptor function under iron overload

1
1. scibot 04 Jul 2025
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.3389/fimmu.2025.1605420
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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pmc.ncbi.nlm.nih.gov/articles/PMC12213461/
bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com

Brain miR-137 governs growth and development via GH/IGF-1 signaling

1
1. scibot 03 Jul 2025
  
  in Public
  
  Strain No.003574
  
  DOI: 10.1186/s12915-025-02306-8
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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bmcbiol.biomedcentral.com/articles/10.1186/s12915-025-02306-8
Jun 2025
www.sciencedirect.com www.sciencedirect.com

RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation

1
1. scibot 26 Jun 2025
  
  in Public
  
  Jackson Laboratory Cat_003574
  
  DOI: 10.1016/j.cmet.2025.05.014
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRIDCUR:Unresolved RRID:IMSR_JAX:003574
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scibot

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sciencedirect.com/science/article/pii/S1550413125002943
www.sciencedirect.com www.sciencedirect.com

Comparative analysis of mouse strains for in vivo induction of reprogramming factors

1
1. scibot 25 Jun 2025
  
  in Public
  
  Jackson LaboratoryStock No: 003574
  
  DOI: 10.1016/j.celrep.2025.115879
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S2211124725006503
52.53.155.43 52.53.155.43

1-s2.0-S2589004225011939-main-html.html

1
1. scibot 18 Jun 2025
  
  in Public
  
  JAX:003574
  
  DOI: 10.1016/j.isci.2025.112932
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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RRID:IMSR_JAX:003574

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52.53.155.43/41ee7f7c4d03a161945c3364f420059e19e16098/1-s2.0-S2589004225011939-main-html.html
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells

1
1. scibot 21 May 2025
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.7554/eLife.101299
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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pmc.ncbi.nlm.nih.gov/articles/PMC12055005/
Apr 2025
www.sciencedirect.com www.sciencedirect.com

Type I interferons induce guanylate-binding proteins and lysosomal defense in hepatocytes to control malaria

1
1. scibot 01 Apr 2025
  
  in Public
  
  JAX:003574
  
  DOI: 10.1016/j.chom.2025.03.008
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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RRID:IMSR_JAX:003574

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sciencedirect.com/science/article/pii/S1931312825000915
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Protocol to evaluate fasting metabolism and its relationship to the core circadian clock in mice

1
1. scibot 06 Mar 2025
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.xpro.2025.103660
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S2666166725000668
52.53.155.43 52.53.155.43

1-s2.0-S2589004225004110-main-html.html

1
1. scibot 06 Mar 2025
  
  in Public
  
  JAX:003574
  
  DOI: 10.1016/j.isci.2025.112151
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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RRID:IMSR_JAX:003574

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scibot

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52.53.155.43/71b100c2da4b391812dc0546081536f527a1e350/1-s2.0-S2589004225004110-main-html.html
Feb 2025
www.sciencedirect.com www.sciencedirect.com

Hepatic sphingomyelin phosphodiesterase 3 promotes steatohepatitis by disrupting membrane sphingolipid metabolism

1
1. scibot 27 Feb 2025
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.cmet.2025.01.016
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S1550413125000166
www.nature.com www.nature.com

Sox9 inhibits Activin A to promote biliary maturation and branching morphogenesis

1
1. scibot 21 Feb 2025
  
  in Public
  
  JAX #003574
  
  DOI: 10.1038/s41467-025-56813-x
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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RRID:IMSR_JAX:003574

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scibot

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nature.com/articles/s41467-025-56813-x
elifesciences.org elifesciences.org

Impact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology

1
1. scibot 21 Feb 2025
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.7554/eLife.99141
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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elifesciences.org/articles/99141
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Spatially restricted and ontogenically distinct hepatic macrophages are required for tissue repair

1
1. scibot 28 Jan 2025
  
  in Public
  
  JAX:003574
  
  DOI: 10.1016/j.immuni.2025.01.002
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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scibot

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sciencedirect.com/science/article/pii/S1074761325000020
Dec 2024
www.sciencedirect.com www.sciencedirect.com

SPTLC3 regulates plasma membrane sphingolipid composition to facilitate hepatic gluconeogenesis

1
1. scibot 12 Dec 2024
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.celrep.2024.115054
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S2211124724014050
www.sciencedirect.com www.sciencedirect.com

Spatial organizations of heterochromatin underpin nuclear structural integrity of ventricular cardiomyocytes against mechanical stress

1
1. scibot 10 Dec 2024
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.celrep.2024.115048
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S2211124724013998
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FAK is required for c-Met/β-catenin-driven hepatocarcinogenesis

1
1. scibot 22 Nov 2024
  
  in Public
  
  003574
  
  DOI: 10.1002/hep.27402
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @AleksanderDrozdz
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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RRID:IMSR_JAX:003574

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC4280291/
www.sciencedirect.com www.sciencedirect.com

A β-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites

1
1. scibot 14 Nov 2024
  
  in Public
  
  003574
  
  DOI: 10.1016/j.cell.2024.10.032
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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RRID:IMSR_JAX:003574

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scibot

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sciencedirect.com/science/article/pii/S0092867424012145
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Paneth cell TNF signaling induces gut bacterial translocation and sepsis

1
1. scibot 10 Sep 2024
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.chom.2024.08.007
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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RRID:IMSR_JAX:003574

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sciencedirect.com/science/article/pii/S1931312824003147
Aug 2024
www.sciencedirect.com www.sciencedirect.com

Hepatic BMAL1 and HIF1α regulate a time-dependent hypoxic response and prevent hepatopulmonary-like syndrome

1
1. scibot 13 Aug 2024
  
  in Public
  
  Jackson Laboratories003574
  
  DOI: 10.1016/j.cmet.2024.07.003
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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RRID:IMSR_JAX:003574

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scibot

URL

sciencedirect.com/science/article/pii/S1550413124002742
Jul 2024
www.cell.com www.cell.com

Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver

1
1. scibot 19 Jul 2024
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.celrep.2024.114400
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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cell.com/cell-reports/abstract/S2211-1247(24)00728-9
52.53.155.43 52.53.155.43

research.0435-html.html

1
1. scibot 11 Jul 2024
  
  in Public
  
  The Jackson Laboratory, 003574
  
  DOI: 10.34133/research.0435
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574 DOI:10.34133/research.0435
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DOI:10.34133/research.0435

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52.53.155.43/a7f04caa88f9444036bc33f95ca42247b9d59475/research.0435-html.html
Jun 2024
www.sciencedirect.com www.sciencedirect.com

FoxO1 suppresses Fgf21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance

1
1. scibot 18 Jun 2024
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.celrep.2021.108893
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRIDCUR:Validated RRID:IMSR_JAX:003574
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RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721002072
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mecp2 fine-tunes quiescence exit by targeting nuclear receptors

1
1. scibot 17 May 2024
  
  in Public
  
  The Jackson LaboratoryCat# 003574
  
  DOI: 10.7554/eLife.89912
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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ncbi.nlm.nih.gov/pmc/articles/PMC11095939/
www.sciencedirect.com www.sciencedirect.com

Reprogramming tumor-associated macrophages and inhibiting tumor neovascularization by targeting MANF-HSF1-HSP70-1 pathway: An effective treatment for hepatocellular carcinoma

1
1. scibot 14 May 2024
  
  in Public
  
  RRID: IMSR_JAX: 003574
  
  DOI: 10.1016/j.apsb.2024.05.001
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S2211383524001795
www.sciencedirect.com www.sciencedirect.com

A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1

1
1. scibot 08 May 2024
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.cmet.2024.04.015
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S1550413124001359
Mar 2024
www.sciencedirect.com www.sciencedirect.com

Transketolase promotes MAFLD by limiting inosine-induced mitochondrial activity

1
1. scibot 28 Mar 2024
  
  in Public
  
  The Jackson LaboratoryCat#003574
  
  DOI: 10.1016/j.cmet.2024.03.003
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574
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RRID:IMSR_JAX:003574

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scibot

URL

sciencedirect.com/science/article/pii/S1550413124000822
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Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT

1
1. scibot 06 Mar 2024
  
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  Jackson LaboratoriesCat# 003574
  
  DOI: 10.1016/j.celrep.2024.113881
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability

1
1. scibot 06 Mar 2024
  
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  Jackson Labs)Cat. #003574
  
  DOI: 10.1016/j.cmet.2024.02.004
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S1550413124000500
Feb 2024
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Gut-liver axis calibrates intestinal stem cell fitness

1
1. scibot 06 Feb 2024
  
  in Public
  
  The Jackson LaboratoryCat# 003574
  
  DOI: 10.1016/j.cell.2024.01.001
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S0092867424000035
Jan 2024
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Downregulation of the kidney glucagon receptor, essential for renal function and systemic homeostasis, contributes to chronic kidney disease

1
1. scibot 19 Jan 2024
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.cmet.2023.12.024
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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Ergosterol peroxide blocks HDV infection as a novel entry inhibitor by targeting human NTCP receptor

1
1. scibot 07 Jan 2024
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.biopha.2023.116077
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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www.sciencedirect.com:5037 www.sciencedirect.com:5037

Serine synthesis via reversed SHMT2 activity drives glycine depletion and acetaminophen hepatotoxicity in MASLD

1
1. scibot 06 Jan 2024
  
  in Public
  
  The Jackson LaboratoryCat# 003574
  
  DOI: 10.1016/j.cmet.2023.12.013
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com:5037/science/article/pii/S1550413123004643
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Under peroxisome proliferation acyl-CoA oxidase coordinates with catalase to enhance ethanol metabolism

1
1. scibot 03 Jan 2024
  
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  003574
  
  DOI: 10.1016/j.freeradbiomed.2023.08.016
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @bandrow
  
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sciencedirect.com/science/article/pii/S0891584923005889
Dec 2023
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Epinephrine inhibits PI3Kα via the Hippo kinases

1
1. scibot 20 Dec 2023
  
  in Public
  
  Jackson laboratoriesStock No: 003574
  
  DOI: 10.1016/j.celrep.2023.113535
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @evieth
  
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hepatic Huwe1 loss protects mice from non-alcoholic fatty liver disease through lipid metabolic rewiring

1
1. scibot 06 Dec 2023
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.isci.2023.108405
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10692727/
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Liver receptor homolog-1 (NR5A2) orchestrates hepatic inflammation and TNF-induced cell death

1
1. scibot 02 Dec 2023
  
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  JAX:003574
  
  DOI: 10.1016/j.celrep.2023.113513
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S2211124723015255
Nov 2023
link.springer.com link.springer.com

Hepatocyte integrity depends on c-Jun-controlled proliferation in Schistosoma mansoni infected mice

1
1. scibot 25 Nov 2023
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.1038/s41598-023-47646-z
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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link.springer.com/article/10.1038/s41598-023-47646-z
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Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria

1
1. scibot 10 Nov 2023
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.celrep.2023.113389
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S2211124723014018
Jul 2023
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Kynurenine monooxygenase regulates inflammation during critical illness and recovery in experimental acute pancreatitis

1
1. scibot 21 Jul 2023
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.celrep.2023.112763
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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Inositol polyphosphate multikinase modulates redox signaling through nuclear factor erythroid 2-related factor 2 and glutathione metabolism

1
1. scibot 15 Jul 2023
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.isci.2023.107199
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S2589004223012762
May 2023
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FOXK1 promotes nonalcoholic fatty liver disease by mediating mTORC1-dependent inhibition of hepatic fatty acid oxidation

1
1. scibot 20 May 2023
  
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  JAX:003574
  
  DOI: 10.1016/j.celrep.2023.112530
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S2211124723005417
link.springer.com link.springer.com

Atransgenic mouse line for assaying tissue-specific changes in endoplasmic reticulum proteostasis

1
1. scibot 04 May 2023
  
  in Public
  
  RRID:IMSR_JAX:003
  
  DOI: 10.1007/s11248-023-00349-7
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @a5munoz
  
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  RRID:IMSR_JAX:003574 RRIDCUR:Unresolved
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link.springer.com/article/10.1007/s11248-023-00349-7
Apr 2023
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Central growth hormone action regulates neuroglial and proinflammatory markers in the hypothalamus of male mice

1
1. scibot 08 Apr 2023
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.neulet.2023.137236
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S0304394023001933
Jan 2023
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Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma

1
1. scibot 26 Jan 2023
  
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  Stock No:003574
  
  DOI: 10.1016/j.devcel.2022.12.012
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S1534580722008942
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Chimeric efferocytic receptors improve apoptotic cell clearance and alleviate inflammation

1
1. scibot 10 Jan 2023
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.cell.2022.11.029
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S0092867422015045
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome

1
1. scibot 09 Nov 2022
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.1073/pnas.2210434119
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9636906/
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier

1
1. scibot 27 Oct 2022
  
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  JAX:003574
  
  DOI: 10.7554/eLife.80690
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9596162/
52.53.155.43 52.53.155.43

Centriole signaling restricts hepatocyte ploidy to maintain liver integrity

1
1. scibot 27 Oct 2022
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1101/gad.349727.122
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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52.53.155.43/27d2faf8da2c0ce1e6065d96eb324b873fb45bb8/Genes Dev.-2022-Sladky-843-56-html.html
Sep 2022
www.sciencedirect.com www.sciencedirect.com

Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice

1
1. scibot 16 Sep 2022
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.molmet.2022.101589
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S2212877822001582
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma

1
1. scibot 02 Sep 2022
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1158/2159-8290.CD-21-1077
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8904298/
Aug 2022
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Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma

1
1. scibot 31 Aug 2022
  
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  JAX:003574
  
  DOI: 10.1016/j.celrep.2022.111253
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S2211124722010713
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Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis

1
1. scibot 04 Aug 2022
  
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  JAX:003574
  
  DOI: 10.1016/j.cmet.2022.07.006
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S1550413122003059
Jun 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis

1
1. scibot 03 Jun 2022
  
  in Public
  
  Jackson LaboratoryStock no.: 003574
  
  DOI: 10.1016/j.chom.2022.05.006
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @sophiastull
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9841318/
Apr 2022
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WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy

1
1. scibot 20 Apr 2022
  
  in Public
  
  The Jackson Laboratory,#003574
  
  DOI: 10.1016/j.molcel.2022.03.027
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S1097276522002659
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Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure

1
1. scibot 07 Apr 2022
  
  in Public
  
  Jackson laboratory003574
  
  DOI: 10.1016/j.cmet.2022.03.005
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S1550413122000936
Mar 2022
www.nature.com www.nature.com

CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver

1
1. scibot 23 Mar 2022
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.1038/s41596-021-00677-0
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
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nature.com/articles/s41596-021-00677-0
Jan 2022
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Apolipoprotein E derived from CD11c+ cells ameliorates atherosclerosis

1
1. scibot 12 Jan 2022
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.isci.2021.103677
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S2589004221016473
Dec 2021
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TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver

1
1. scibot 21 Dec 2021
  
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  Stock#003574
  
  DOI: 10.1016/j.cmet.2021.11.013
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @Naa003
  
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  RRIDCUR:Missing RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S1550413121005416
www.nature.com www.nature.com

A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

1
1. scibot 21 Dec 2021
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.1038/s41467-021-27452-9
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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nature.com/articles/s41467-021-27452-9
Nov 2021
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APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis

1
1. scibot 09 Nov 2021
  
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  Stock#003574
  
  DOI: 10.1016/j.immuni.2021.10.004
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S1074761321004106
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TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states

1
1. scibot 05 Nov 2021
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.7554/eLife.57462
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8555985/
Oct 2021
www.embopress.org www.embopress.org

Reprogramming of glucocorticoid receptor function by hypoxia

1
1. scibot 27 Oct 2021
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.15252/embr.202153083
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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embopress.org/doi/full/10.15252/embr.202153083
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Glycogen accumulation and phase separation drives liver tumor initiation

1
1. scibot 22 Oct 2021
  
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  Stock No: 003574
  
  DOI: 10.1016/j.cell.2021.10.001
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S0092867421011752
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Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinase

1
1. scibot 08 Oct 2021
  
  in Public
  
  RRID:IMSR_JAX
  
  DOI: 10.1016/j.celrep.2021.109785
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
  Curator comments: B6.Cg-Speer6-ps1Tg(Alb-cre)21Mgn/J Mus musculus IMSR Cat# JAX:003574
  
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  RRID:IMSR_JAX:003574 RRIDCUR:Unresolved RRIDCUR:SyntaxError
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sciencedirect.com/science/article/pii/S2211124721012444
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation

1
1. scibot 08 Sep 2021
  
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  Stock No: 003574
  
  DOI: 10.1016/j.celrep.2021.109659
  
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  RRIDCUR:Missing RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S2211124721011037
Aug 2021
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Hepatic nitric oxide synthase 1 adaptor protein regulates glucose homeostasis and hepatic insulin sensitivity in obese mice depending on its PDZ binding domain

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.ebiom.2019.08.033
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:003574 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2352396419305584
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Activin E Controls Energy Homeostasis in Both Brown and White Adipose Tissues as a Hepatokine

2
1. scibot 30 Jul 2021
  
  in Public
  
  JAX:003574
  
  DOI: 10.1016/j.celrep.2018.10.008
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574 RRIDCUR:Duplicate RRIDCUR:Validated
2. scibot 30 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.celrep.2018.10.008
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S2211124718315717
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GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis

1
1. scibot 29 Jul 2021
  
  in Public
  
  RRID: IMSR_JAX:003574
  
  DOI: 10.1016/j.cell.2019.10.034
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S0092867419312115
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Diabetes reversal by inhibition of the low molecular weight tyrosine phosphatase

1
1. scibot 27 Jul 2021
  
  in Public
  
  003574
  
  DOI: 10.1038/nchembio.2344
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5435566/
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Untitled document

1
1. scibot 27 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX
  
  DOI: 10.1016/j.cell.2019.02.013
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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  RRID:IMSR_JAX:003574 RRIDCUR:Unresolved
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sciencedirect.com/science/article/pii/S009286741930162X
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Time-Restricted Feeding Prevents Obesity and Metabolic Syndrome in Mice Lacking a Circadian Clock

1
1. scibot 27 Jul 2021
  
  in Public
  
  RRID:MSR_JAX:003574
  
  DOI: 10.1016/j.cmet.2018.08.004
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRID:IMSR_JAX:003574 RRIDCUR:Unresolved RRIDCUR:Incorrect
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sciencedirect.com/science/article/pii/S1550413118305059
www.sciencedirect.com www.sciencedirect.com

Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis

1
1. scibot 24 Jul 2021
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.cmet.2021.07.002
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S1550413121003181
Jun 2021
www.sciencedirect.com www.sciencedirect.com

Hepatocyte membrane potential regulates serum insulin and insulin sensitivity by altering hepatic GABA release

1
1. scibot 30 Jun 2021
  
  in Public
  
  JAX stock 003574
  
  DOI: 10.1016/j.celrep.2021.109298
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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  RRID:IMSR_JAX:003574 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124721006744
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Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1

1
1. scibot 19 Jun 2021
  
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  Cat#003574
  
  DOI: 10.1016/j.cmet.2021.05.019
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @Naa003
  
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  RRID:IMSR_JAX:003574 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1550413121002709
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells

1
1. scibot 17 Jun 2021
  
  in Public
  
  JAX:003574
  
  DOI: 10.1371/journal.ppat.1009593
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8172060/
May 2021
www.sciencedirect.com www.sciencedirect.com

PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation

1
1. scibot 08 May 2021
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.molcel.2021.01.032
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1097276521000526
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Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:IMSR_JAX
  
  DOI: 10.1016/j.devcel.2020.05.024
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
  Curator comments: B6.Cg-Speer6-ps1Tg(Alb-cre)21Mgn/J Mus musculus IMSR Cat# JAX:003574
  
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  RRIDCUR:Unresolved RRID:IMSR_JAX:003574 RRIDCUR:SyntaxError
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sciencedirect.com/science/article/pii/S1534580720304135
Apr 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Intercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism

1
1. scibot 30 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.cmet.2020.11.009
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7858244/
www.sciencedirect.com www.sciencedirect.com

Deletion of Fructokinase in the Liver or in the Intestine Reveals Differential Effects on Sugar-Induced Metabolic Dysfunction

1
1. scibot 29 Apr 2021
  
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  003574
  
  DOI: 10.1016/j.cmet.2020.05.012
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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  RRIDCUR:Missing RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S1550413120302515
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TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation

1
1. scibot 29 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.cmet.2020.10.010
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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  RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S155041312030543X
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Identification of ALK in Thinness

1
1. scibot 23 Apr 2021
  
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  Stock No 003574
  
  DOI: 10.1016/j.cell.2020.04.034
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @Naa003
  
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  RRID:IMSR_JAX:003574 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S0092867420304979
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The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine

1
1. scibot 22 Apr 2021
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.cmet.2021.03.025
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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  RRIDCUR:Validated RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S1550413121001662
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PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression

1
1. scibot 17 Apr 2021
  
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  Stock No: 003574
  
  DOI: 10.1016/j.ccell.2020.05.018
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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  RRID:IMSR_JAX:003574 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1535610820302683
Mar 2021
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FoxO1 suppresses Fgf21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance

1
1. scibot 24 Mar 2021
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.celrep.2021.108893
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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sciencedirect.com/science/article/pii/S2211124721002072
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS

1
1. scibot 28 Feb 2021
  
  in Public
  
  JAX:003574
  
  DOI: 10.1016/j.ccell.2017.05.006
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7909318/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism

1
1. scibot 27 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.7554/eLife.59258
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7723411/
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Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas

1
1. scibot 24 Feb 2021
  
  in Public
  
  Stock# 003574
  
  DOI: 10.1016/j.celrep.2021.108772
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @Naa003
  
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  RRIDCUR:Missing RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S2211124721000851
Jan 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21

1
1. scibot 13 Jan 2021
  
  in Public
  
  JAX:003574
  
  DOI: 10.1101/gad.344556.120
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @evieth
  
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  RRID:IMSR_JAX:003574 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7778269/
Dec 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor

1
1. scibot 07 Dec 2020
  
  in Public
  
  RRID:IMSR_JAX:003574
  
  DOI: 10.7554/eLife.58069
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRIDCUR:Validated RRID:IMSR_JAX:003574
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ncbi.nlm.nih.gov/pmc/articles/PMC7688313/
Sep 2020
www.pnas.org www.pnas.org

JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma

1
1. scibot 13 Sep 2020
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.1073/pnas.2002672117
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
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  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRIDCUR:Validated RRID:IMSR_JAX:003574
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pnas.org/content/117/28/16492
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Novel aspects of glutamine synthetase in ammonia homeostasis

1
1. scibot 06 Sep 2020
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.neuint.2020.104809
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:003574
  
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  RRIDCUR:Validated RRID:IMSR_JAX:003574
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sciencedirect.com/science/article/pii/S019701862030200X
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Liver haploinsufficiency of RuvBL1 causes hepatic insulin resistance and enhances hepatocellular carcinoma progression

1
1. scibot 04 Sep 2020
  
  in Public
  
  B6.Cg‐Tg(Alb‐cre)21Mgn/J
  
  DOI: 10.1002/ijc.32787
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @Naa003
  
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  Curator comments: B6.Cg-Speer6-ps1Tg(Alb-cre)21Mgn/J Mus musculus IMSR Cat# JAX:003574
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32787
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JARID1a Ablation in the Liver Alters Systemic Metabolism and Adaptation to Feeding

1
1. scibot 03 Sep 2020
  
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  The Jackson Laboratorystock 003574
  
  DOI: 10.1016/j.celrep.2020.107668
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2211124720306215
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Ovariectomy uncouples lifespan from metabolic health and reveals a sex-hormone-dependent role of hepatic mTORC2 in aging

1
1. scibot 03 Sep 2020
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.7554/eLife.56177
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @evieth
  
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elifesciences.org/articles/56177
Aug 2020
advances.sciencemag.org advances.sciencemag.org

Control of protein function through oxidation and reduction of persulfidated states

1
1. scibot 14 Aug 2020
  
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  JAX#003574
  
  DOI: 10.1126/sciadv.aax8358
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @Naa003
  
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  Curator comments: B6.Cg-Speer6-ps1Tg(Alb-cre)21Mgn/J Mus musculus IMSR Cat# JAX:003574
  
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advances.sciencemag.org/content/6/1/eaax8358
Jan 2020
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Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease

1
1. scibot 13 Jan 2020
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.cell.2019.11.026
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S0092867419312838
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Untitled document

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1. scibot 12 Jan 2020
  
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  RRID:IMSR_JAX:003574
  
  DOI: 10.1016/j.cmet.2019.03.001
  
  Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1550413119301299
Nov 2018
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γ-Secretase Inhibition Lowers Plasma Triglyceride-Rich Lipoproteins by Stabilizing the LDL Receptor

1
1. scibot 05 Nov 2018
  
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  003574
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1550413118301219
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis

1
1. scibot 05 Nov 2018
  
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  003574
  
  Curator: @Jmenke
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6300139/
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Small RNAs Are Trafficked from the Epididymis to Developing Mammalian Sperm

1
1. scibot 05 Nov 2018
  
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  RRID:IMSR_JAX:003574
  
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sciencedirect.com/science/article/pii/S1534580718305409
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Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis

1
1. scibot 05 Nov 2018
  
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  003574
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1931312818302634
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Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling

1
1. scibot 05 Nov 2018
  
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  003574
  
  Curator: @Jmenke
  
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Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling

1
1. scibot 05 Nov 2018
  
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  003574
  
  Curator: @Jmenke
  
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AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity

1
1. scibot 05 Nov 2018
  
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  RRID:IMSR_JAX:003574
  
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sciencedirect.com/science/article/pii/S1550413118301323
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Untitled document

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1. scibot 05 Nov 2018
  
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  RRID:IMSR_JAX:003574
  
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journals.sagepub.com/doi/full/10.1369/0022155417749828
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metabolic Adaptation Establishes Disease Tolerance to Sepsis

1
1. scibot 05 Nov 2018
  
  in Public
  
  Jackson Laboratories; stock 003574
  
  Curator: @bandrow
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5480394/
Nov 2017
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The FGF21-CCL11 Axis Mediates Beiging of White Adipose Tissues by Coupling Sympathetic Nervous System to Type 2 Immunity

1
1. scibot 08 Nov 2017
  
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  003574
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1550413117304886
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Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS

1
1. scibot 08 Nov 2017
  
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  JAX:003574
  
  Curator: @Jmenke
  
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  RRID:IMSR_JAX:003574 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610817302027
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Metabolic Adaptation Establishes Disease Tolerance to Sepsis

1
1. scibot 08 Nov 2017
  
  in Public
  
  JAX stock 003574
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S0092867417305925

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