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Dietary saturated fatty acids promote lung myeloid cell inflammasome activation and IL-1β–mediated inflammation in mice and humans

1
1. scibot 04 Sep 2025
  
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  JAX, no. 004650
  
  DOI: 10.1126/scitranslmed.adp5653
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650
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science.org/doi/10.1126/scitranslmed.adp5653
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Structure of gut microbial glycolipid modulates host inflammatory response

1
1. scibot 23 Jul 2025
  
  in Public
  
  RRID:IMSR_JAX:004650
  
  DOI: 10.1016/j.cell.2025.05.016
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650
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sciencedirect.com/science/article/pii/S0092867425005665
Jul 2024
journals.plos.org journals.plos.org

The lipopeptide Pam3CSK4 inhibits Rift Valley fever virus infection and protects from encephalitis

1
1. scibot 04 Jul 2024
  
  in Public
  
  RRID:IMSR_JAX:004650
  
  DOI: 10.1371/journal.ppat.1012343
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650
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journals.plos.org/plospathogens/article
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TLR2 regulates hair follicle cycle and regeneration via BMP signaling

1
1. scibot 16 Mar 2024
  
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  RRID:IMSR_JAX:004650
  
  DOI: 10.7554/eLife.89335
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650
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ncbi.nlm.nih.gov/pmc/articles/PMC10939499/
Nov 2022
www.sciencedirect.com www.sciencedirect.com

BlpC-mediated selfish program leads to rapid loss of Streptococcus pneumoniae clonal diversity during infection

1
1. scibot 17 Nov 2022
  
  in Public
  
  RRID:IMSR_JAX:004650
  
  DOI: 10.1016/j.chom.2022.10.015
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650
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sciencedirect.com/science/article/pii/S1931312822005285
Sep 2022
www.sciencedirect.com www.sciencedirect.com

Human gut microbiota stimulate defined innate immune responses that vary from phylum to strain

1
1. scibot 13 Sep 2022
  
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  RRID:IMSR_JAX:004650
  
  DOI: 10.1016/j.chom.2022.08.009
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650
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sciencedirect.com/science/article/pii/S1931312822004085
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment

1
1. scibot 17 Aug 2022
  
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  The Jackson Laboratory004650
  
  DOI: 10.1016/j.celrep.2022.111201
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650
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sciencedirect.com/science/article/pii/S221112472201018X
May 2022
www.sciencedirect.com www.sciencedirect.com

Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity

1
1. scibot 19 May 2022
  
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  The Jackson LaboratoryStock No: 004650
  
  DOI: 10.1016/j.celrep.2022.110837
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650
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sciencedirect.com/science/article/pii/S2211124722006106
Feb 2022
www.sciencedirect.com www.sciencedirect.com

A TLR/CD44 axis regulates T cell trafficking in experimental and human multiple sclerosis

1
1. scibot 02 Feb 2022
  
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  RRID:IMSR_JAX:004650
  
  DOI: 10.1016/j.isci.2022.103763
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650
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sciencedirect.com/science/article/pii/S2589004222000335
Dec 2021
www.sciencedirect.com www.sciencedirect.com

The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota

1
1. scibot 11 Dec 2021
  
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  Cat#004650
  
  DOI: 10.1016/j.xcrm.2021.100464
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRIDCUR:Missing RRID:IMSR_JAX:004650
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RRIDCUR:Missing

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sciencedirect.com/science/article/pii/S2666379121003360
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming

1
1. scibot 24 Sep 2021
  
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  Stock#004650
  
  DOI: 10.1016/j.cmet.2021.09.002
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRIDCUR:Missing RRID:IMSR_JAX:004650
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sciencedirect.com/science/article/pii/S1550413121004216
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Interleukin-1 causes CNS inflammatory cytokine expression via endothelia-microglia bi-cellular signaling

1
1. scibot 29 Jul 2021
  
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  004650
  
  DOI: 10.1016/j.bbi.2019.06.026
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRIDCUR:Missing RRID:IMSR_JAX:004650
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sciencedirect.com/science/article/pii/S0889159118307621
www.sciencedirect.com www.sciencedirect.com

Dysregulated Lung Commensal Bacteria Drive Interleukin-17B Production to Promote Pulmonary Fibrosis through Their Outer Membrane Vesicles

1
1. scibot 28 Jul 2021
  
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  004650
  
  DOI: 10.1016/j.immuni.2019.02.001
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650
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sciencedirect.com/science/article/pii/S1074761319300469
Jun 2021
insight.jci.org insight.jci.org

MMP2 and TLRs modulate immune responses in the tumor microenvironment

1
1. scibot 29 Jun 2021
  
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  JAX:004650
  
  DOI: 10.1172/jci.insight.144913
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650
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insight.jci.org/articles/view/144913
www.cell.com www.cell.com

Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota

1
1. scibot 24 Jun 2021
  
  in Public
  
  Jax 004650
  
  DOI: 10.1016/j.cell.2021.05.020
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650 RRIDCUR:Missing
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RRID:IMSR_JAX:004650

RRIDCUR:Missing

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cell.com/cell/fulltext/S0092-8674(21)00650-4
May 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Toll-like receptor 2 activation and up-regulation by high mobility group box-1 contribute to post-operative neuroinflammation and cognitive dysfunction in mice

1
1. scibot 20 May 2021
  
  in Public
  
  RRID:IMSR_JAX:004650
  
  DOI: 10.1111/jnc.15368
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650
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onlinelibrary.wiley.com/doi/10.1111/jnc.15368
Mar 2021
www.sciencedirect.com www.sciencedirect.com

Fatty acid chain length drives lysophosphatidylserine-dependent immunological outputs

1
1. scibot 29 Mar 2021
  
  in Public
  
  RRID:IMSR_JAX:004650
  
  DOI: 10.1016/j.chembiol.2021.01.008
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650
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RRID:IMSR_JAX:004650

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sciencedirect.com/science/article/pii/S2451945621000088
Feb 2021
www.nature.com www.nature.com

Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection

1
1. scibot 25 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:004650
  
  DOI: 10.1038/s41564-020-0756-3
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650
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nature.com/articles/s41564-020-0756-3
Oct 2020
www.sciencedirect.com www.sciencedirect.com

Hyperactivity of Innate Immunity Triggers Pain via TLR2-IL-33-Mediated Neuroimmune Crosstalk

1
1. scibot 08 Oct 2020
  
  in Public
  
  TLR2 ko
  
  DOI: 10.1016/j.celrep.2020.108233
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
  Curator comments: B6.129-Tlr2tm1Kir/J Mus musculus IMSR Cat# JAX:004650
  
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  RRID:IMSR_JAX:004650 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124720312225
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration

1
1. scibot 03 Sep 2020
  
  in Public
  
  JAX stock #004650
  
  DOI: 10.1016/j.celrep.2020.01.064
  
  Resource: (IMSR Cat# JAX_004650,RRID:IMSR_JAX:004650)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
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  RRID:IMSR_JAX:004650
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RRID:IMSR_JAX:004650

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sciencedirect.com/science/article/pii/S2211124720300899
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Temporal Regulation of the Bacterial Metabolite Deoxycholate during Colonic Repair Is Critical for Crypt Regeneration

1
1. scibot 05 Nov 2018
  
  in Public
  
  JAX 004650
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:004650
  
  SciCrunch record: RRID:IMSR_JAX:004650
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:004650 RRIDCUR:Missing
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RRID:IMSR_JAX:004650

RRIDCUR:Missing

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scibot

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sciencedirect.com/science/article/pii/S1931312818303895