547 Matching Annotations
  1. Apr 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Succinyl-CoA Ligase Deficiency in Pro-inflammatory and Tissue-Invasive T Cells
    1
    1. scibot 30 Apr 2021
      Stock#005557

      DOI: 10.1016/j.cmet.2020.10.025

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    sciencedirect.com/science/article/pii/S1550413120305945
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    Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells
    1
    1. scibot 29 Apr 2021
      005557

      DOI: 10.1016/j.cmet.2020.10.017

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    sciencedirect.com/science/article/pii/S1550413120305507
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    Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance
    1
    1. scibot 29 Apr 2021
      005557

      DOI: 10.1016/j.cmet.2020.07.009

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    sciencedirect.com/science/article/pii/S1550413120303673
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    Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells
    1
    1. scibot 29 Apr 2021
      Stock No: 005557

      DOI: 10.1016/j.cmet.2020.07.008

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    sciencedirect.com/science/article/pii/S1550413120303661
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    The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development
    1
    1. scibot 29 Apr 2021
      JAX- 005557

      DOI: 10.1016/j.cmet.2020.05.008

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    sciencedirect.com/science/article/pii/S1550413120302473
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    Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections
    1
    1. scibot 29 Apr 2021
      Stock No: 005557

      DOI: 10.1016/j.immuni.2021.04.002

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    sciencedirect.com/science/article/pii/S1074761321001394
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    An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity
    1
    1. scibot 28 Apr 2021
      005557

      DOI: 10.1016/j.chembiol.2020.11.012

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    sciencedirect.com/science/article/pii/S245194562030475X
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    Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma
    1
    1. scibot 28 Apr 2021
      Cat#005557

      DOI: 10.1016/j.celrep.2021.109013

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    sciencedirect.com/science/article/pii/S2211124721003272
  10. www.sciencedirect.com www.sciencedirect.com
    Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
    1
    1. scibot 24 Apr 2021
      005557

      DOI: 10.1016/j.cell.2020.07.009

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    sciencedirect.com/science/article/pii/S0092867420308746
  11. www.sciencedirect.com www.sciencedirect.com
    Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis
    1
    1. scibot 24 Apr 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2021.01.022

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    sciencedirect.com/science/article/pii/S0092867421000659
  12. www.sciencedirect.com www.sciencedirect.com
    Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies
    1
    1. scibot 24 Apr 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2020.08.022

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    sciencedirect.com/science/article/pii/S0092867420310138
  13. rupress.org rupress.org
    Human KIT+ myeloid cells facilitate visceral metastasis by melanoma
    1
    1. scibot 24 Apr 2021
      JAX:005557

      DOI: 10.1084/jem.20182163

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    rupress.org/jem/article/218/6/e20182163/211995/Human-KIT-myeloid-cells-facilitate-visceral
  14. www.sciencedirect.com www.sciencedirect.com
    MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism
    1
    1. scibot 22 Apr 2021
      005557

      DOI: 10.1016/j.ccell.2021.02.006

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    sciencedirect.com/science/article/pii/S1535610821001082
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    A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation
    1
    1. scibot 22 Apr 2021
      Ref 5557

      DOI: 10.1016/j.ccell.2021.02.003

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    sciencedirect.com/science/article/pii/S1535610821001057
  16. www.sciencedirect.com www.sciencedirect.com
    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
    1
    1. scibot 22 Apr 2021
      005557

      DOI: 10.1016/j.ccell.2020.10.010

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    sciencedirect.com/science/article/pii/S1535610820305419
  17. www.sciencedirect.com www.sciencedirect.com
    Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance
    1
    1. scibot 22 Apr 2021
      JAX:005557

      DOI: 10.1016/j.ccell.2020.12.023

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    sciencedirect.com/science/article/pii/S1535610820306711
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    Emergence of a High-Plasticity Cell State during Lung Cancer Evolution
    1
    1. scibot 20 Apr 2021
      005557

      DOI: 10.1016/j.ccell.2020.06.012

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    sciencedirect.com/science/article/pii/S1535610820303160
  19. www.sciencedirect.com www.sciencedirect.com
    Mass spectrometry analysis of circulating breast cancer cells from a Xenograft mouse model
    1
    1. scibot 20 Apr 2021
      Cat# 5557

      DOI: 10.1016/j.xpro.2021.100480

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    sciencedirect.com/science/article/pii/S2666166721001878
  20. www.sciencedirect.com www.sciencedirect.com
    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
    1
    1. scibot 20 Apr 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2020.07.008

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    sciencedirect.com/science/article/pii/S153561082030369X
  21. www.sciencedirect.com www.sciencedirect.com
    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
    1
    1. scibot 17 Apr 2021
      Strain# 005557

      DOI: 10.1016/j.ccell.2020.04.014

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    sciencedirect.com/science/article/pii/S1535610820302130
  22. www.sciencedirect.com www.sciencedirect.com
    Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
    1
    1. scibot 17 Apr 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2020.04.017

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    sciencedirect.com/science/article/pii/S1535610820302166
  23. www.sciencedirect.com www.sciencedirect.com
    Dissecting the impact of regional identity and the oncogenic role of human-specific NOTCH2NL in an hESC model of H3.3G34R-mutant glioma
    1
    1. scibot 11 Apr 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2021.02.003

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    sciencedirect.com/science/article/pii/S1934590921000539
  24. Mar 2021
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells
    1
    1. scibot 28 Mar 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1158/2643-3230.BCD-20-0161

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    ncbi.nlm.nih.gov/pmc/articles/PMC7610449/
  26. Feb 2021
  27. www.nature.com www.nature.com
    Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51
    1
    1. scibot 28 Feb 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1038/s41418-020-00733-4

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    nature.com/articles/s41418-020-00733-4
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues
    1
    1. scibot 28 Feb 2021
      RRID:IMSR_JAX:005557

      DOI: 10.7554/eLife.61980

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    ncbi.nlm.nih.gov/pmc/articles/PMC7847306/
  29. www.cell.com www.cell.com
    Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01
    1
    1. scibot 26 Feb 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2021.01.004

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    cell.com/cell-stem-cell/abstract/S1934-5909(21)00004-7
  30. www.sciencedirect.com www.sciencedirect.com
    Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants
    1
    1. scibot 25 Feb 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2021.01.016

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    sciencedirect.com/science/article/pii/S1934590921000163
  31. insight.jci.org insight.jci.org
    Asymmetric cell division promotes therapeutic resistance in glioblastoma stem cells
    1
    1. scibot 14 Feb 2021
      S

      DOI: 10.1172/jci.insight.130510

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      Curator: @bandrow

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    insight.jci.org/articles/view/130510/sd/1
  32. www.sciencedirect.com www.sciencedirect.com
    A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)
    1
    1. scibot 03 Feb 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ebiom.2021.103220

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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S235239642100013X
  33. www.sciencedirect.com www.sciencedirect.com
    Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis
    1
    1. scibot 01 Feb 2021
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2020.11.012

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    sciencedirect.com/science/article/pii/S0092867420315294
  34. Jan 2021
  35. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins
    1
    1. scibot 07 Jan 2021
      Cat# 005557

      DOI: 10.1016/j.celrep.2020.108532

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    sciencedirect.com/science/article/pii/S2211124720315217
  36. www.sciencedirect.com www.sciencedirect.com
    Piwil1 Regulates Glioma Stem Cell Maintenance and Glioblastoma Progression
    1
    1. scibot 07 Jan 2021
      NSG mice

      DOI: 10.1016/j.celrep.2020.108522

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    sciencedirect.com/science/article/pii/S2211124720315114
  37. Dec 2020
  38. www.sciencedirect.com www.sciencedirect.com
    Tracking HIV Rebound following Latency Reversal Using Barcoded HIV
    1
    1. scibot 24 Dec 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2020.100162

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    sciencedirect.com/science/article/pii/S2666379120302093
  39. www.sciencedirect.com www.sciencedirect.com
    Lgr5 Marks Adult Progenitor Cells Contributing to Skeletal Muscle Regeneration and Sarcoma Formation
    1
    1. scibot 24 Dec 2020
      JAX:005557

      DOI: 10.1016/j.celrep.2020.108535

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    sciencedirect.com/science/article/pii/S2211124720315242
  40. www.sciencedirect.com www.sciencedirect.com
    Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells
    1
    1. scibot 15 Dec 2020
      NOD-scidIL2Rgammanull

      DOI: 10.1016/j.celrep.2020.108482

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      Curator: @Naa003

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      Curator comments: NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ Mus musculus IMSR Cat# JAX:005557

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    sciencedirect.com/science/article/pii/S2211124720314716
  41. www.sciencedirect.com www.sciencedirect.com
    Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis
    1
    1. scibot 15 Dec 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2020.108473

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      RRID:IMSR_JAX:005557 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720314625
  42. www.sciencedirect.com www.sciencedirect.com
    The Master Regulator Protein BAZ2B Can Reprogram Human Hematopoietic Lineage-Committed Progenitors into a Multipotent State
    1
    1. scibot 13 Dec 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2020.108474

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    sciencedirect.com/science/article/pii/S2211124720314637
  43. link.springer.com link.springer.com
    Melanoma cells can be eliminated by sialylated CD43 × CD3 bispecific T cell engager formats in vitro and in vivo
    1
    1. scibot 07 Dec 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1007/s00262-020-02780-9

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    link.springer.com/article/10.1007/s00262-020-02780-9
  44. Nov 2020
  45. www.sciencedirect.com www.sciencedirect.com
    Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.xcrm.2020.100131

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    sciencedirect.com/science/article/pii/S2666379120301737
  46. Oct 2020
  47. www.sciencedirect.com www.sciencedirect.com
    Assessing the Safety of a Cell-Based Immunotherapy for Brain Cancers Using a Humanized Model of Hematopoiesis
    1
    1. scibot 10 Oct 2020
      NOD-scid IL2Rgammanull (NSG) Mouse

      DOI: 10.1016/j.xpro.2020.100124

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    sciencedirect.com/science/article/pii/S2666166720301118
  48. Sep 2020
  49. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Human T Cells Expressing a CD19 CAR-T Receptor Provide Insights into Mechanisms of Human CD19-Positive β Cell Destruction
    1
    1. scibot 26 Sep 2020
      NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) mice

      DOI: 10.1016/j.xcrm.2020.100097

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  50. www.sciencedirect.com www.sciencedirect.com
    Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2020.05.039

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  51. www.sciencedirect.com www.sciencedirect.com
    Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2020.02.002

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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
    1
    1. scibot 26 Sep 2020
      RRID:IMSR_JAX:005557

      DOI: 10.7554/eLife.56913

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    ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
  53. www.sciencedirect.com www.sciencedirect.com
    Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2020.08.016

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  54. www.sciencedirect.com www.sciencedirect.com
    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2020.107840

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  55. www.sciencedirect.com www.sciencedirect.com
    A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2020.03.004

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    Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.stem.2020.02.001

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  57. www.sciencedirect.com www.sciencedirect.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2020.02.019

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  58. www.sciencedirect.com www.sciencedirect.com
    LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma LIN28B Control of EWS-FLI1 Stability
    1
    1. scibot 16 Sep 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2019.12.053

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    sciencedirect.com/science/article/pii/S2211124719317103
  59. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2019.12.007

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  60. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Proteomic profiling of the ECM of xenograft breast cancer metastases in different organs reveals distinct metastatic niches
    1
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      JAX:005557

      DOI: 10.1158/0008-5472.CAN-19-2961

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    cancerres.aacrjournals.org/content/80/7/1475
  61. www.sciencedirect.com www.sciencedirect.com
    Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2020.03.008

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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation
    1
    1. scibot 13 Sep 2020
      RRID:IMSR_JAX:005557

      DOI: 10.7554/eLife.53381

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    ncbi.nlm.nih.gov/pmc/articles/PMC7200154/
  63. www.sciencedirect.com www.sciencedirect.com
    A Cancer-Specific Ubiquitin Ligase Drives mRNA Alternative Polyadenylation by Ubiquitinating the mRNA 3′ End Processing Complex
    1
    1. scibot 11 Sep 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.molcel.2019.12.022

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    sciencedirect.com/science/article/pii/S1097276519309529
  64. www.sciencedirect.com www.sciencedirect.com
    Single-Cell Transcriptome Profiling Reveals β Cell Maturation in Stem Cell-Derived Islets after Transplantation
    1
    1. scibot 09 Sep 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2020.108067

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    sciencedirect.com/science/article/pii/S2211124720310524
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Axon-like protrusions promote small cell lung cancer migration and metastasis
    1
    1. scibot 08 Sep 2020
      RRID:IMSR_JAX:005557

      DOI: 10.7554/eLife.50616

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    ncbi.nlm.nih.gov/pmc/articles/PMC6940020/
  66. www.sciencedirect.com www.sciencedirect.com
    Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia
    1
    1. scibot 05 Sep 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.chembiol.2020.04.002

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    sciencedirect.com/science/article/pii/S2451945620301161
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer
    1
    1. scibot 05 Sep 2020
      RRID:IMSR_JAX:005557

      DOI: 10.7554/eLife.57679

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    ncbi.nlm.nih.gov/pmc/articles/PMC7302877/
  68. www.sciencedirect.com www.sciencedirect.com
    Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis
    1
    1. scibot 04 Sep 2020
      Mouse: NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ

      DOI: 10.1016/j.cell.2020.03.047

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    sciencedirect.com/science/article/pii/S0092867420303408
  69. www.sciencedirect.com www.sciencedirect.com
    Senescence, Necrosis, and Apoptosis Govern Circulating Cell-free DNA Release Kinetics
    1
    1. scibot 04 Sep 2020
      Nod-Scid-Gamma

      DOI: 10.1016/j.celrep.2020.107830

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    sciencedirect.com/science/article/pii/S2211124720308111
  70. www.nature.com www.nature.com
    Rapid generation of Col7a1 −/− mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells
    1
    1. scibot 04 Sep 2020
      NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ

      DOI: 10.1038/labinvest.2017.85

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    nature.com/articles/labinvest201785
  71. www.jci.org www.jci.org
    Chronic myelogenous leukemia stem cells require cell-autonomous pleiotrophin signaling
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    1. scibot 04 Sep 2020
      C57BL/6

      DOI: 10.1172/JCI129061

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    jci.org/articles/view/129061
  72. www.nature.com www.nature.com
    The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer
    1
    1. scibot 04 Sep 2020
      NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ NSG

      DOI: 10.1038/s41388-020-1196-5

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    nature.com/articles/s41388-020-1196-5
  73. www.nature.com www.nature.com
    Human immune cells infiltrate the spinal cord and impair recovery after spinal cord injury in humanized mice
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    1. scibot 04 Sep 2020
      Jackson Laboratory (strain #005557

      DOI: 10.1038/s41598-019-55729-z

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    nature.com/articles/s41598-019-55729-z
  74. www.nature.com www.nature.com
    Isolation of satellite cells and transplantation into mice for lineage tracing in muscle
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    1. scibot 04 Sep 2020
      JAX, cat no. 005557

      DOI: 10.1038/s41596-019-0278-8

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  75. www.sciencedirect.com www.sciencedirect.com
    Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells
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    1. scibot 03 Sep 2020
      Jackson Laboratory005557

      DOI: 10.1016/j.celrep.2020.107688

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    Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2
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    1. scibot 03 Sep 2020
      The Jackson LaboratoryCat#005557

      DOI: 10.1016/j.cell.2020.03.051

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    MYC Controls the Epstein-Barr Virus Lytic Switch
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      The Jackson Laboratory005557

      DOI: 10.1016/j.molcel.2020.03.025

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    ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase
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      The Jackson Laboratory005557

      DOI: 10.1016/j.cmet.2020.03.008

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    Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer
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      The Jackson LaboratoryCat# 005557

      DOI: 10.1016/j.stem.2020.02.008

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    Cancer Cells Resist Mechanical Destruction in Circulation via RhoA/Actomyosin-Dependent Mechano-Adaptation
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      The Jackson Laboratory005557

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    Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
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      Jackosn LabsStock No: 005557

      DOI: 10.1016/j.ccell.2020.01.011

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    Comparison of Human Antral Follicles of Xenograft versus Ovarian Origin Reveals Disparate Molecular Signatures
    1
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      female NSG

      DOI: 10.1016/j.celrep.2020.108027

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    Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity
    1
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      NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG™)

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  84. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Protocol for Cloning Epithelial Stem Cell Variants from Human Lung
    1
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      NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ

      DOI: 10.1016/j.xpro.2020.100063

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  85. Aug 2020
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    Neutralizing Antibodies Protect against Oral Transmission of Lymphocryptovirus
    1
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      The Jackson LaboratoryStock No: 005557

      DOI: 10.1016/j.xcrm.2020.100033

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    Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2019.12.003

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  88. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Exosome/Microvesicle Content is Altered in LRRK2 Mutant iPSC‐derived Neural Cells
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      The Jackson Laboratory, Stock# 005557

      DOI: 10.1002/cne.24819

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    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
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      RRID:IMSR_JAX:005557

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  90. Jan 2020
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    Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.molcel.2019.06.001

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  92. cancerres.aacrjournals.org cancerres.aacrjournals.org
    HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress
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      RRID:IMSR_JAX:005557

      DOI: 10.1158/0008-5472.CAN-18-1377

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    CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies
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    Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network
    1
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      RRID:IMSR_JAX:005557

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    Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2019.08.105

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    BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2019.06.005

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    Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG
    1
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      RRID:IMSR_JAX:005557

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    UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma
    1
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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cell.2019.08.032

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      JAX:005557

      DOI: 10.1016/j.stem.2018.12.003

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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2019.01.006

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    Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.ccell.2019.02.003

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      RRID:IMSR_JAX005557

      DOI: 10.1016/j.celrep.2019.03.085

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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.celrep.2018.12.090

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      RRID:IMSR_JAX:005557

      DOI: 10.1016/j.cels.2018.10.005

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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells
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      RRID:IMSR_JAX:005557

      DOI: 10.1038/s41408-018-0165-5

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      JAX:005557

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  107. Nov 2018
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    Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations
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      005557

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    A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression
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      RRID:IMSR_JAX:005557

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    TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy
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      005557

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    Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages
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      RRID:IMSR_JAX:005557

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    Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells
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      005557

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    ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer
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      005557

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    3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
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      005557

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    An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis
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    Mutant NPM1 Maintains the Leukemic State through HOX Expression
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    Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance
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    Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway
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    Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
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    Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells
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      005557

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    Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

      Resource used:

      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S193459091830016X
  123. www.sciencedirect.com www.sciencedirect.com
    Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

      Resource used:

      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S0092867418309097
  124. www.sciencedirect.com www.sciencedirect.com
    Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

      Resource used:

      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1934590918302844
  125. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential
    1
    1. scibot 05 Nov 2018
      JAX:005557

      Resource used:

      RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1934590917305118
  126. www.sciencedirect.com www.sciencedirect.com
    Small Interfering RNA-Mediated Control of Virus Replication in the CNS Is Therapeutic and Enables Natural Immunity to West Nile Virus
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1931312818300982
  127. www.sciencedirect.com www.sciencedirect.com
    An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance
    1
    1. scibot 05 Nov 2018
      005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S0092867418303842
  128. www.sciencedirect.com www.sciencedirect.com
    The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1097276518301084
  129. www.sciencedirect.com www.sciencedirect.com
    The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1535610818301739
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557

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    ncbi.nlm.nih.gov/pmc/articles/PMC6643283/
  131. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:005557

      Resource used:

      RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1535610817305020
  132. www.sciencedirect.com www.sciencedirect.com
    Cytosolic Iron-Sulfur Assembly Is Evolutionarily Tuned by a Cancer-Amplified Ubiquitin Ligase
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:005557

      Resource used:

      RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1097276517308456
  133. europepmc.org europepmc.org
    TCF7L1 promotes skin tumorigenesis independently of β-catenin through induction of LCN2.
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557

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    europepmc.org/articles/PMC5438253/
  134. Nov 2017
  135. www.sciencedirect.com www.sciencedirect.com
    Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia
    1
    1. scibot 08 Nov 2017
      005557

      Curator: @Jmenke

      Resource used:

      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1535610817303641
  136. www.sciencedirect.com www.sciencedirect.com
    Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling
    1
    1. scibot 08 Nov 2017
      005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1535610817304075
  137. www.sciencedirect.com www.sciencedirect.com
    Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming
    1
    1. scibot 08 Nov 2017
      005557

      Curator: @Jmenke

      Resource used:

      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1934590917303387
  138. www.sciencedirect.com www.sciencedirect.com
    Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single-Step Transformation by KRAS Mutations
    1
    1. scibot 08 Nov 2017
      005557

      Curator: @Jmenke

      Resource used:

      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1535610817303495
  139. www.sciencedirect.com www.sciencedirect.com
    Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
    1
    1. scibot 08 Nov 2017
      RRID:IMSR_JAX:005557

      Curator: @Jmenke

      Resource used:

      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1535610817303471
  140. www.sciencedirect.com www.sciencedirect.com
    Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Disease Progression and Drug Response in Acute Myeloid Leukemia
    1
    1. scibot 08 Nov 2017
      005557

      Curator: @Jmenke

      Resource used:

      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1535610817303069
  141. www.sciencedirect.com www.sciencedirect.com
    Prostaglandin E1 and Its Analog Misoprostol Inhibit Human CML Stem Cell Self-Renewal via EP4 Receptor Activation and Repression of AP-1
    1
    1. scibot 08 Nov 2017
      JAX:005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1934590917303193
  142. www.sciencedirect.com www.sciencedirect.com
    Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia
    1
    1. scibot 08 Nov 2017
      005557

      Curator: @Jmenke

      Resource used:

      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1934590917300310
  143. elifesciences.org elifesciences.org
    Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids
    1
    1. scibot 08 Nov 2017
      RRID:IMSR_JAX:005557

      Resource used:

      RRID:IMSR_JAX:005557

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    elifesciences.org/articles/26575
  144. www.sciencedirect.com www.sciencedirect.com
    Stable and Potent Selenomab-Drug Conjugates
    1
    1. scibot 08 Nov 2017
      005557

      Curator: @Jmenke @bandrow

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S2451945617300600
  145. www.sciencedirect.com www.sciencedirect.com
    Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia
    1
    1. scibot 08 Nov 2017
      005557

      Curator: @Jmenke

      Resource used:

      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1535610817300636
  146. www.sciencedirect.com www.sciencedirect.com
    Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein α Signaling
    1
    1. scibot 08 Nov 2017
      Jax:005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1074761317303230
  147. www.sciencedirect.com www.sciencedirect.com
    Prevention of intestinal ischemia-reperfusion injury in humanized mice
    1
    1. scibot 08 Nov 2017
      NOD.PkSCID.IL2 receptor gamma chain null mice

      Curator: @bandrow

      Curator note: Author verified by email

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    sciencedirect.com/science/article/pii/S003960601600163X
  148. www.sciencedirect.com www.sciencedirect.com
    Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression
    1
    1. scibot 08 Nov 2017
      NOD/LtSz-scid IL2Rgnull (NSG mice)The Jackson LaboratoryStock#005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1931312817302494
  149. www.sciencedirect.com www.sciencedirect.com
    A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis
    1
    1. scibot 08 Nov 2017
      Mouse: NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG)The Jackson LaboratoryStock # 005557

      Curator: @Jmenke

      Resource used:

      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1535610817302039
  150. www.sciencedirect.com www.sciencedirect.com
    Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation
    1
    1. scibot 08 Nov 2017
      JAX005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1550413117303005
  151. www.sciencedirect.com www.sciencedirect.com
    Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma
    1
    1. scibot 08 Nov 2017
      NSG NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ miceThe Jackson LaboratoryStock: 005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1934590917301376
  152. www.sciencedirect.com www.sciencedirect.com
    BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment
    1
    1. scibot 08 Nov 2017
      Mouse: NSG: NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJThe Jackson LaboratoryCat#005557

      Curator: @Jmenke

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1097276517304069
  153. www.sciencedirect.com www.sciencedirect.com
    ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells
    1
    1. scibot 08 Nov 2017
      IMSR_JAX:005557

      Curator: @chewbeccax

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1934590917302308
  154. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma
    1
    1. scibot 08 Nov 2017
      Stock No. 005557

      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S1535610817301071
  155. www.sciencedirect.com www.sciencedirect.com
    Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes
    1
    1. scibot 08 Nov 2017
      IMSR_JAX:005557

      Curator: @gabimpine

      Resource used:

      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1550413117301705
  156. www.sciencedirect.com www.sciencedirect.com
    Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression
    1
    1. scibot 08 Nov 2017
      JAX: 005557

      Curator: @Zeljana_Babic

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S193459091630457X
  157. www.sciencedirect.com www.sciencedirect.com
    Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease
    1
    1. scibot 08 Nov 2017
      Cat# 005557

      Curator: @Zeljana_Babic

      Resource used:

      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    sciencedirect.com/science/article/pii/S1934590916304544
  158. www.cell.com www.cell.com
    Interspecies Chimerism with Mammalian Pluripotent Stem Cells
    1
    1. scibot 08 Nov 2017
      Stock No: 005557

      Curator: @Zeljana_Babic

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      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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    cell.com/action/showMethods
  159. www.sciencedirect.com www.sciencedirect.com
    A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds
    1
    1. scibot 08 Nov 2017
      NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ

      Curator: @gabimpine

      Resource used:

      RRID:IMSR_JAX:005557

      SciCrunch record: RRID:IMSR_JAX:005557

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      RRID:IMSR_JAX:005557 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867416311382