175 Matching Annotations
  1. Jul 2025
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    CMTR1-catalyzed 2′-O-methylation promotes NMDA receptor signaling, long-term potentiation and memory
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    sciencedirect.com/science/article/pii/S0301008225000930
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    VIRMA-mediated m6A modification regulates forebrain formation through modulating ribosome biogenesis
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    science.org/doi/10.1126/sciadv.adq9643
  4. May 2025
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elevated pyramidal cell firing orchestrates arteriolar vasoconstriction through COX-2-derived prostaglandin E2 signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12017770/
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    Oncogenic fusions converge on shared mechanisms in initiating astroblastoma
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    link.springer.com/article/10.1038/s41586-025-08981-5
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    Activity-dependent degradation of Kv4.2 contributes to synaptic plasticity and behavior in Angelman syndrome model mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12232208/
  8. Apr 2025
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    Activity-dependent synthesis of Emerin gates neuronal plasticity by regulating proteostasis
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    sciencedirect.com/science/article/pii/S2211124725002104
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    The dorsal column nuclei scale mechanical sensitivity in naive and neuropathic pain states
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    sciencedirect.com/science/article/pii/S2211124725003274
  11. www.biorxiv.org www.biorxiv.org
    Highly selective visual receptive fields in mouse frontal cortex
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    biorxiv.org/content/10.1101/2025.03.25.645272v1
  12. Mar 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Radial glia integrin avb8 regulates cell autonomous microglial TGFβ1 signaling that is necessary for microglial identity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11929771/
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    Cell-type-specific roles of FOXP1 in the excitatory neuronal lineage during early neocortical murine development
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    sciencedirect.com/science/article/pii/S221112472500155X
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    Development of Differential Sublaminar Feedforward Inhibitory Circuits in CA1 Hippocampus Requires Satb2
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    jneurosci.org/content/45/8/e0737242024
  16. Feb 2025
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    Presymptomatic targeted circuit manipulation for ameliorating Huntington’s disease pathogenesis
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    sciencedirect.com/science/article/pii/S2589004225002822
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Translaminar synchronous neuronal activity is required for columnar synaptic strengthening in the mouse neocortex
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    pmc.ncbi.nlm.nih.gov/articles/PMC11791040/
  19. Jan 2025
  20. www.biorxiv.org www.biorxiv.org
    Epigenetic priming of neural progenitors by Notch enhances Sonic hedgehog signaling and establishes gliogenic competence
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    biorxiv.org/content/10.1101/2025.01.20.633996v1
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    Syngap1 promotes cognitive function through regulation of cortical sensorimotor dynamics
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    pmc.ncbi.nlm.nih.gov/articles/PMC11743135/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cyclin-dependent kinase inhibitor p18 regulates lineage transitions of excitatory neurons, astrocytes, and interneurons in the mouse cortex
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    pmc.ncbi.nlm.nih.gov/articles/PMC11730326/
  23. Dec 2024
  24. www.biorxiv.org www.biorxiv.org
    Cortical projection neurons with distinct axonal connectivity employ ribosomal complexes with distinct protein compositions
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    biorxiv.org/content/10.1101/2024.12.22.629968v2
  25. www.biorxiv.org www.biorxiv.org
    Ciliopathy interacts with neonatal anesthesia to cause non-apoptotic caspase-mediated motor deficits
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    biorxiv.org/content/10.1101/2024.11.27.624302v1
  26. Nov 2024
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rasopathy-Associated Mutation Ptpn11D61Y has Age-Dependent Effect on Synaptic Vesicle Recycling
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    pmc.ncbi.nlm.nih.gov/articles/PMC11582327/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC2840225/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap
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    pmc.ncbi.nlm.nih.gov/articles/PMC4302891/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tuning instability of non-columnar neurons in the salt-and-pepper whisker map in somatosensory cortex
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    pmc.ncbi.nlm.nih.gov/articles/PMC9633707/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A whole-brain monosynaptic input connectome to neuron classes in mouse visual cortex
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    pmc.ncbi.nlm.nih.gov/articles/PMC10039800/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EphB1 controls long-range cortical axon guidance through a cell non-autonomous role in GABAergic cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC10946438/
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    Syngap1 Promotes Cognitive Function through Regulation of Cortical Sensorimotor Dynamics
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    pmc.ncbi.nlm.nih.gov/articles/PMC10557642/
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    APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints
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  35. Sep 2024
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    Daily oscillations of neuronal membrane capacitance
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    sciencedirect.com/science/article/pii/S2211124724010957
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    Disruption of NMDA receptor function prevents normal experience-dependent homeostatic synaptic plasticity in mouse primary visual cortex
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    jneurosci.org/content/39/39/7664
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Embryonic origins of forebrain oligodendrocytes revisited by combinatorial genetic fate mapping
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  39. Aug 2024
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    Effective knockdown-replace gene therapy in a novel mouse model of DNM1 developmental and epileptic encephalopathy
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  41. www.nature.com www.nature.com
    Facemap: a framework for modeling neural activity based on orofacial tracking
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    nature.com/articles/s41593-023-01490-6
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  43. Jul 2024
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    Presymptomatic Targeted Circuit Manipulation for Ameliorating Huntington’s Disease Pathogenesis
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    biorxiv.org/content/10.1101/2024.07.24.604946v1
  45. Jun 2024
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental effect of RASopathy mutations on neuronal network activity on a chip
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    ncbi.nlm.nih.gov/pmc/articles/PMC11190344/
  47. May 2024
  48. 52.53.155.43 52.53.155.43
    Prenatal tuning of thalamic spontaneous activity patterns regulates somatosensory map resolution
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    Dynamic fibroblast-immune interactions shape wound healing after brain injury
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    biorxiv.org/content/10.1101/2024.03.13.584873v1
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parvalbumin interneuron activity in autism underlies susceptibility to PTSD-like memory formation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11089364/
  51. 52.53.155.43 52.53.155.43
    Chemogenetic silencing reveals presynaptic Gi/o protein-mediated inhibition of synchronized activity in the developing hippocampus<i>in vivo</i>
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  52. Apr 2024
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antipsychotic drugs selectively decorrelate long-range interactions in deep cortical layers
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    Overexpression of forebrain PTP1B leads to synaptic and cognitive impairments in obesity
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  55. Mar 2024
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    Multimodal sensory control of motor performance by glycinergic interneurons of the mouse spinal cord deep dorsal horn
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    sciencedirect.com/science/article/pii/S0896627324000539
  57. Jan 2024
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    Time-lapse imaging of cortical projection neuron migration in mice using mosaic analysis with double markers
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    sciencedirect.com/science/article/pii/S2666166723007621
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    Fine-tuning GPCR-mediated neuromodulation by biasing signaling through different G protein subunits
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    sciencedirect.com/science/article/pii/S1097276523004288
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tle4 controls both developmental acquisition and early post-natal maturation of corticothalamic projection neuron identity
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    pmc.ncbi.nlm.nih.gov/articles/PMC10542749/
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    Excitation creates a distributed pattern of cortical suppression due to varied recurrent input
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  62. www.jneurosci.org www.jneurosci.org
    Selective Deletion of Methyl CpG Binding Protein 2 from Parvalbumin Interneurons in the Auditory Cortex Delays the Onset of Maternal Retrieval in Mice
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    jneurosci.org/content/43/40/6745
  63. Dec 2023
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    Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala
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  65. Nov 2023
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    Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities
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    sciencedirect.com/science/article/pii/S2211124723015085
  67. Oct 2023
  68. www.nature.com www.nature.com
    Neural deficits in a mouse model of PACS1 syndrome are corrected with PACS1- or HDAC6-targeting therapy
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    nature.com/articles/s41467-023-42176-8
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radial glia promote microglial development through integrin αVβ8 -TGFβ1 signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10542141/
  70. www.jneurosci.org www.jneurosci.org
    KCNQ2/3 Gain-of-Function Variants and Cell Excitability: Differential Effects in CA1 vs. L2/3 pyramidal neurons
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    jneurosci.org/content/43/38/6479
  71. Sep 2023
  72. www.biorxiv.org www.biorxiv.org
    Developmental effect of RASopathy mutations on neuronal network activity on a chip
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    biorxiv.org/content/10.1101/2023.09.20.558464v1
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    Molecularly targetable cell types in mouse visual cortex have distinguishable prediction error responses
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  75. Jun 2023
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    Direct and indirect neurogenesis generate a mosaic of distinct glutamatergic projection neuron types in cerebral cortex
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    Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice
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    nature.com/articles/s41596-023-00831-w
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    Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
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    nature.com/articles/s41467-023-39203-z
  79. May 2023
  80. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nonspecific labeling limits the utility of Cre‐Lox bred CST‐YFP mice for studies of corticospinal tract regeneration
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    onlinelibrary.wiley.com/doi/10.1002/cne.23809/full
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    Amplified cortical neural responses as animals learn to use novel activity patterns
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    sciencedirect.com/science/article/pii/S0960982223004803
  82. Apr 2023
  83. www.sciencedirect.com www.sciencedirect.com
    Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development
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    sciencedirect.com/science/article/pii/S1534580723001326
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    Integrin β3 regulates apical dendritic morphology of pyramidal neurons throughout hippocampal CA3
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    onlinelibrary.wiley.com/doi/10.1002/hipo.23530
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bicistronic expression of a high-performance calcium indicator and opsin for all-optical stimulation and imaging at cellular resolution
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    ncbi.nlm.nih.gov/pmc/articles/PMC10062490/
  86. Mar 2023
  87. www.sciencedirect.com www.sciencedirect.com
    Large neutral amino acid levels tune perinatal neuronal excitability and survival
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    Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations
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    Upregulation of SYNGAP1 expression in mice and human neurons by redirecting alternative splicing
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A transcriptional constraint mechanism limits the homeostatic response to activity deprivation in mammalian neocortex
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    ncbi.nlm.nih.gov/pmc/articles/PMC10010687/
  91. Feb 2023
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA-targeted therapy corrects neuronal deficits in PACS1 syndrome mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9901029/
  93. www.sciencedirect.com www.sciencedirect.com
    Regional and cell-type-specific afferent and efferent projections of the mouse claustrum
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    sciencedirect.com/science/article/pii/S2211124723001298
  94. Dec 2022
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Network instability dynamics drive a transient bursting period in the developing hippocampus in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC9762703/
  96. Oct 2022
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    miR-409-3p represses Cited2 to refine neocortical layer V projection neuron identity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9558290/
  98. Sep 2022
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    Functionally distinct NPAS4-expressing somatostatin interneuron ensembles critical for motor skill learning
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    sciencedirect.com/science/article/pii/S0896627322007541
  100. Aug 2022
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The rapid developmental rise of somatic inhibition disengages hippocampal dynamics from self-motion
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    ncbi.nlm.nih.gov/pmc/articles/PMC9363116/
  102. Jun 2022
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant cortical development is driven by impaired cell cycle and translational control in a DDX3X syndrome model
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    ncbi.nlm.nih.gov/pmc/articles/PMC9239684/
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    Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
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    Phosphatidylinositol transfer protein/planar cell polarity axis regulates neocortical morphogenesis by supporting interkinetic nuclear migration
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  106. May 2022
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    Increased glycine contributes to synaptic dysfunction and early mortality in Nprl2 seizure model
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  108. Apr 2022
  109. www.sciencedirect.com www.sciencedirect.com
    Simultaneous brain cell type and lineage determined by scRNA-seq reveals stereotyped cortical development
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    sciencedirect.com/science/article/pii/S2405471222001338
  110. www.sciencedirect.com www.sciencedirect.com
    Continuity within the somatosensory cortical map facilitates learning
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    sciencedirect.com/science/article/pii/S2211124722003655
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neocortical Projection Neurons Instruct Inhibitory Interneuron Circuit Development in a Lineage-Dependent Manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC8965597/
  112. Feb 2022
  113. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development
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    pubmed.ncbi.nlm.nih.gov/35196485/
  114. Jan 2022
  115. www.sciencedirect.com www.sciencedirect.com
    ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder
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    sciencedirect.com/science/article/pii/S0896627321010904
  116. www.sciencedirect.com www.sciencedirect.com
    History-dependent dopamine release increases cAMP levels in most basal amygdala glutamatergic neurons to control learning
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    sciencedirect.com/science/article/pii/S2211124722000031
  117. Nov 2021
  118. www.sciencedirect.com www.sciencedirect.com
    Genetic mosaic dissection of candidate genes in mice using mosaic analysis with double markers
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    sciencedirect.com/science/article/pii/S2666166721006456
  119. Oct 2021
  120. www.sciencedirect.com www.sciencedirect.com
    NuMorph: Tools for cortical cellular phenotyping in tissue-cleared whole-brain images
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  121. Sep 2021
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    Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells
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  123. Aug 2021
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXP2 exhibits projection neuron class specific expression, but is not required for multiple aspects of cortical histogenesis
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