34 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor α
    3
    1. scibot 09 Apr 2024
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2024.114056

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    2. scibot 09 Apr 2024
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2024.114056

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    3. scibot 09 Apr 2024
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2024.114056

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    sciencedirect.com/science/article/pii/S221112472400384X
  3. Mar 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Pten regulates endocytic trafficking of cell adhesion and Wnt signaling molecules to pattern the retina
    1
    1. scibot 29 Mar 2024
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2024.114005

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    sciencedirect.com/science/article/pii/S2211124724003334
  5. Jan 2024
  6. link.springer.com link.springer.com
    Distinct mesenchymal cell states mediate prostate cancer progression
    1
    1. scibot 11 Jan 2024
      RRID:IMSR_JAX:006440

      DOI: 10.1038/s41467-023-44210-1

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    link.springer.com/article/10.1038/s41467-023-44210-1
  7. Dec 2023
  8. www.sciencedirect.com www.sciencedirect.com
    De novo NAD+ synthesis contributes to CD8+ T cell metabolic fitness and antitumor function
    1
    1. scibot 21 Dec 2023
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2023.113518

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    sciencedirect.com/science/article/pii/S2211124723015309
  9. Mar 2023
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neurovascular development in Pten and Tsc2 mouse mutants
    1
    1. scibot 02 Mar 2023
      RRID:IMSR_JAX:006440

      DOI: 10.1523/ENEURO.0340-22.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC9953070/
  11. Nov 2022
  12. www.sciencedirect.com www.sciencedirect.com
    Targeting PTEN but not SOCS3 resists an age-dependent decline in promoting axon sprouting
    1
    1. scibot 10 Nov 2022
      The Jackson Laboratory006440

      DOI: 10.1016/j.isci.2022.105383

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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S2589004222016558
  13. www.sciencedirect.com www.sciencedirect.com
    Disruption of mTORC1 rescues neuronal overgrowth and synapse function dysregulated by Pten loss
    1
    1. scibot 03 Nov 2022
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2022.111574

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    sciencedirect.com/science/article/pii/S2211124722014358
  14. Aug 2022
  15. www.sciencedirect.com www.sciencedirect.com
    Single-cell transcriptome analysis of regenerating RGCs reveals potent glaucoma neural repair genes
    1
    1. scibot 12 Aug 2022
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.neuron.2022.06.022

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    sciencedirect.com/science/article/pii/S0896627322006018
  16. Jul 2022
  17. www.sciencedirect.com www.sciencedirect.com
    PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis
    1
    1. scibot 27 Jul 2022
      JAX# 006440

      DOI: 10.1016/j.celrep.2022.111125

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      Curator: @sophiastull

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    sciencedirect.com/science/article/pii/S2211124722009317
  18. Jun 2022
  19. www.sciencedirect.com www.sciencedirect.com
    Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells
    1
    1. scibot 29 Jun 2022
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.neuron.2022.06.002

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    sciencedirect.com/science/article/pii/S0896627322005402
  20. www.sciencedirect.com www.sciencedirect.com
    Muscle satellite cells are impaired in type 2 diabetic mice by elevated extracellular adenosine
    1
    1. scibot 03 Jun 2022
      The Jackson LaboratoryStock No: 006440

      DOI: 10.1016/j.celrep.2022.110884

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      Curator: @sophiastull

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    sciencedirect.com/science/article/pii/S2211124722006593
  21. May 2022
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage-derived cholesterol contributes to therapeutic resistance in prostate cancer
    1
    1. scibot 04 May 2022
      JAX 006440

      DOI: 10.1158/0008-5472.CAN-20-4028

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC8563406/
  23. Jan 2022
  24. www.eneuro.org www.eneuro.org
    An ATF3-CreERT2 Knock-In Mouse for Axotomy-Induced Genetic Editing: Proof of Principle
    1
    1. scibot 29 Jan 2022
      RRID:IMSR_JAX:006440

      DOI: 10.1523/ENEURO.0025-19.2019

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    eneuro.org/content/6/2/ENEURO.0025-19.2019
  25. Nov 2021
  26. www.sciencedirect.com www.sciencedirect.com
    Protein kinase Cι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities
    1
    1. scibot 24 Nov 2021
      Stock# 006440

      DOI: 10.1016/j.celrep.2021.110054

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    sciencedirect.com/science/article/pii/S2211124721015400
  27. Aug 2021
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 13 Aug 2021
      RRID:IMSR_JAX:006440

      DOI: 10.1523/ENEURO.0025-19.2019

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    ncbi.nlm.nih.gov/pmc/articles/PMC6464513/
  29. Jul 2021
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 29 Jul 2021
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2018.09.052

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    ncbi.nlm.nih.gov/pmc/articles/PMC6258034/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling
    2
    1. scibot 29 Jul 2021
      RRID:IMSR_JAX:006440

      DOI: 10.7554/eLife.32021

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      Curator: @evieth

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      RRID:IMSR_JAX:006440 RRIDCUR:Duplicate RRIDCUR:Validated
    2. scibot 29 Jul 2021
      RRID:IMSR_JAX:006440

      DOI: 10.7554/eLife.32021

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC5839742/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytokeratin 19 promoter directs the expression of Cre recombinase in various epithelia of transgenic mice
    1
    1. scibot 27 Jul 2021
      B6.129S4-PTEN tm1Hwu/J

      DOI: 10.18632/oncotarget.15435

      Resource: (IMSR Cat# JAX_006440,RRID:IMSR_JAX:006440)

      Curator: @mpairish

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      RRIDCUR:Missing RRID:IMSR_JAX:006440
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    ncbi.nlm.nih.gov/pmc/articles/PMC5392329/
  33. www.sciencedirect.com www.sciencedirect.com
    Impact of mTOR hyperactive neurons on the morphology and physiology of adjacent neurons: Do PTEN KO cells make bad neighbors?
    1
    1. scibot 27 Jul 2021
      RRID:IMSR_JAX

      DOI: 10.1016/j.expneurol.2019.113029

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      Curator: @bandrow

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      RRIDCUR:Unresolved RRIDCUR:SyntaxError RRID:IMSR_JAX:006440
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    sciencedirect.com/science/article/pii/S0014488619301785
  34. Jun 2021
  35. www.cell.com www.cell.com
    Transient developmental imbalance of cortical interneuron subtypes presages long-term changes in behavior
    1
    1. scibot 16 Jun 2021
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2021.109249

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    cell.com/cell-reports/fulltext/S2211-1247(21)00614-8
  36. May 2021
  37. www.sciencedirect.com www.sciencedirect.com
    mTOR-driven neural circuit changes initiate an epileptogenic cascade
    1
    1. scibot 07 May 2021
      RRID:IMSR_JAX

      DOI: 10.1016/j.pneurobio.2020.101974

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      Curator: @Naa003

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    sciencedirect.com/science/article/pii/S030100822030229X
  38. Sep 2020
  39. www.sciencedirect.com www.sciencedirect.com
    PI3K isoform-selective inhibition in neuron-specific PTEN-deficient mice rescues molecular defects and reduces epilepsy-associated phenotypes
    1
    1. scibot 25 Sep 2020
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.nbd.2020.105026

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    sciencedirect.com/science/article/pii/S0969996120303016
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN suppresses epithelial–mesenchymal transition and cancer stem cell activity by downregulating Abi1
    1
    1. scibot 10 Sep 2020
      RRID:IMSR_JAX:006440

      DOI: 10.1038/s41598-020-69698-1

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC7391766/
  41. Jan 2020
  42. www.sciencedirect.com www.sciencedirect.com
    Thrombospondin-1 Mediates Axon Regeneration in Retinal Ganglion Cells
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.neuron.2019.05.044

      Resource: (IMSR Cat# JAX_006440,RRID:IMSR_JAX:006440)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:006440 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627319304970
  43. www.sciencedirect.com www.sciencedirect.com
    Activity-dependent dendritic elaboration requires Pten
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.nbd.2019.104703

      Resource: (IMSR Cat# JAX_006440,RRID:IMSR_JAX:006440)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:006440 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S096999611930378X
  44. Nov 2018
  45. www.sciencedirect.com www.sciencedirect.com
    The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:006440

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1074761318304357
  46. www.sciencedirect.com www.sciencedirect.com
    Self-reinforcing effects of mTOR hyperactive neurons on dendritic growth
    1
    1. scibot 05 Nov 2018
      RRID: IMSR_JAX STRAIN #006440

      Curator: @bandrow

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      RRID:IMSR_JAX:006440 RRIDCUR:SyntaxError
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    sciencedirect.com/science/article/pii/S0014488618305259
  47. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:006440

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    sciencedirect.com/science/article/pii/S2211124718314979
  48. www.sciencedirect.com www.sciencedirect.com
    EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:006440

      Curator: @anp055

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    sciencedirect.com/science/article/pii/S1535610818302290
  49. www.sciencedirect.com www.sciencedirect.com
    Myelination of Neuronal Cell Bodies when Myelin Supply Exceeds Axonal Demand
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:006440

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S0960982218302549
  50. Nov 2017
  51. www.sciencedirect.com www.sciencedirect.com
    PTEN deletion increases hippocampal granule cell excitability in male and female mice
    1
    1. scibot 08 Nov 2017
      JAX:006440

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0969996117302048