38 Matching Annotations
  1. Last 7 days
  2. www.biorxiv.org www.biorxiv.org
    Glycolytic flux controls retinal progenitor cell differentiation via regulating Wnt signaling
    1
    1. scibot 18 Jul 2024
      RRID:IMSR_JAX:006440

      DOI: 10.1101/2024.07.12.603298

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    biorxiv.org/content/10.1101/2024.07.12.603298v1
  3. Jul 2024
  4. www.cell.com www.cell.com
    Elevating PLK1 overcomes BETi resistance in prostate cancer via triggering BRD4 phosphorylation-dependent degradation in mitosis
    1
    1. scibot 12 Jul 2024
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2024.114431

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    cell.com/cell-reports/fulltext/S2211-1247(24)00760-5
  5. May 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Critical roles of the miR-17∼92 family in thymocyte development, leukemogenesis, and autoimmunity
    1
    1. scibot 23 May 2024
      006440

      DOI: 10.1016/j.celrep.2024.114261

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    sciencedirect.com/science/article/pii/S2211124724005898
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parvalbumin interneuron activity in autism underlies susceptibility to PTSD-like memory formation
    1
    1. scibot 15 May 2024
      JacksonJax 006440

      DOI: 10.1016/j.isci.2024.109747

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    ncbi.nlm.nih.gov/pmc/articles/PMC11089364/
  8. Apr 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor α
    3
    1. scibot 09 Apr 2024
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2024.114056

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    2. scibot 09 Apr 2024
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2024.114056

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    3. scibot 09 Apr 2024
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2024.114056

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    ncbi.nlm.nih.gov/pmc/articles/PMC11112681/
  10. Mar 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Pten regulates endocytic trafficking of cell adhesion and Wnt signaling molecules to pattern the retina
    1
    1. scibot 29 Mar 2024
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2024.114005

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    sciencedirect.com/science/article/pii/S2211124724003334
  12. Jan 2024
  13. link.springer.com link.springer.com
    Distinct mesenchymal cell states mediate prostate cancer progression
    1
    1. scibot 11 Jan 2024
      RRID:IMSR_JAX:006440

      DOI: 10.1038/s41467-023-44210-1

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    link.springer.com/article/10.1038/s41467-023-44210-1
  14. Dec 2023
  15. www.sciencedirect.com www.sciencedirect.com
    De novo NAD+ synthesis contributes to CD8+ T cell metabolic fitness and antitumor function
    1
    1. scibot 21 Dec 2023
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2023.113518

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    sciencedirect.com/science/article/pii/S2211124723015309
  16. Mar 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neurovascular development in Pten and Tsc2 mouse mutants
    1
    1. scibot 02 Mar 2023
      RRID:IMSR_JAX:006440

      DOI: 10.1523/ENEURO.0340-22.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC9953070/
  18. Nov 2022
  19. www.sciencedirect.com www.sciencedirect.com
    Targeting PTEN but not SOCS3 resists an age-dependent decline in promoting axon sprouting
    1
    1. scibot 10 Nov 2022
      The Jackson Laboratory006440

      DOI: 10.1016/j.isci.2022.105383

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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S2589004222016558
  20. www.sciencedirect.com www.sciencedirect.com
    Disruption of mTORC1 rescues neuronal overgrowth and synapse function dysregulated by Pten loss
    1
    1. scibot 03 Nov 2022
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2022.111574

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    sciencedirect.com/science/article/pii/S2211124722014358
  21. Aug 2022
  22. www.sciencedirect.com www.sciencedirect.com
    Single-cell transcriptome analysis of regenerating RGCs reveals potent glaucoma neural repair genes
    1
    1. scibot 12 Aug 2022
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.neuron.2022.06.022

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    sciencedirect.com/science/article/pii/S0896627322006018
  23. Jul 2022
  24. www.sciencedirect.com www.sciencedirect.com
    PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis
    1
    1. scibot 27 Jul 2022
      JAX# 006440

      DOI: 10.1016/j.celrep.2022.111125

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    sciencedirect.com/science/article/pii/S2211124722009317
  25. Jun 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells
    1
    1. scibot 29 Jun 2022
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.neuron.2022.06.002

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    sciencedirect.com/science/article/pii/S0896627322005402
  27. www.sciencedirect.com www.sciencedirect.com
    Muscle satellite cells are impaired in type 2 diabetic mice by elevated extracellular adenosine
    1
    1. scibot 03 Jun 2022
      The Jackson LaboratoryStock No: 006440

      DOI: 10.1016/j.celrep.2022.110884

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    sciencedirect.com/science/article/pii/S2211124722006593
  28. May 2022
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage-derived cholesterol contributes to therapeutic resistance in prostate cancer
    1
    1. scibot 04 May 2022
      JAX 006440

      DOI: 10.1158/0008-5472.CAN-20-4028

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    ncbi.nlm.nih.gov/pmc/articles/PMC8563406/
  30. Jan 2022
  31. www.eneuro.org www.eneuro.org
    An ATF3-CreERT2 Knock-In Mouse for Axotomy-Induced Genetic Editing: Proof of Principle
    1
    1. scibot 29 Jan 2022
      RRID:IMSR_JAX:006440

      DOI: 10.1523/ENEURO.0025-19.2019

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    eneuro.org/content/6/2/ENEURO.0025-19.2019
  32. Nov 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Protein kinase Cι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities
    1
    1. scibot 24 Nov 2021
      Stock# 006440

      DOI: 10.1016/j.celrep.2021.110054

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    sciencedirect.com/science/article/pii/S2211124721015400
  34. Aug 2021
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 13 Aug 2021
      RRID:IMSR_JAX:006440

      DOI: 10.1523/ENEURO.0025-19.2019

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    ncbi.nlm.nih.gov/pmc/articles/PMC6464513/
  36. Jul 2021
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 29 Jul 2021
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2018.09.052

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    ncbi.nlm.nih.gov/pmc/articles/PMC6258034/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling
    2
    1. scibot 29 Jul 2021
      RRID:IMSR_JAX:006440

      DOI: 10.7554/eLife.32021

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    2. scibot 29 Jul 2021
      RRID:IMSR_JAX:006440

      DOI: 10.7554/eLife.32021

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    ncbi.nlm.nih.gov/pmc/articles/PMC5839742/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytokeratin 19 promoter directs the expression of Cre recombinase in various epithelia of transgenic mice
    1
    1. scibot 27 Jul 2021
      B6.129S4-PTEN tm1Hwu/J

      DOI: 10.18632/oncotarget.15435

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      Curator: @mpairish

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    ncbi.nlm.nih.gov/pmc/articles/PMC5392329/
  40. www.sciencedirect.com www.sciencedirect.com
    Impact of mTOR hyperactive neurons on the morphology and physiology of adjacent neurons: Do PTEN KO cells make bad neighbors?
    1
    1. scibot 27 Jul 2021
      RRID:IMSR_JAX

      DOI: 10.1016/j.expneurol.2019.113029

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      Curator: @bandrow

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      RRIDCUR:Unresolved RRIDCUR:SyntaxError RRID:IMSR_JAX:006440
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    sciencedirect.com/science/article/pii/S0014488619301785
  41. Jun 2021
  42. www.cell.com www.cell.com
    Transient developmental imbalance of cortical interneuron subtypes presages long-term changes in behavior
    1
    1. scibot 16 Jun 2021
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.celrep.2021.109249

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    cell.com/cell-reports/fulltext/S2211-1247(21)00614-8
  43. May 2021
  44. www.sciencedirect.com www.sciencedirect.com
    mTOR-driven neural circuit changes initiate an epileptogenic cascade
    1
    1. scibot 07 May 2021
      RRID:IMSR_JAX

      DOI: 10.1016/j.pneurobio.2020.101974

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    sciencedirect.com/science/article/pii/S030100822030229X
  45. Sep 2020
  46. www.sciencedirect.com www.sciencedirect.com
    PI3K isoform-selective inhibition in neuron-specific PTEN-deficient mice rescues molecular defects and reduces epilepsy-associated phenotypes
    1
    1. scibot 25 Sep 2020
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.nbd.2020.105026

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    sciencedirect.com/science/article/pii/S0969996120303016
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN suppresses epithelial–mesenchymal transition and cancer stem cell activity by downregulating Abi1
    1
    1. scibot 10 Sep 2020
      RRID:IMSR_JAX:006440

      DOI: 10.1038/s41598-020-69698-1

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC7391766/
  48. Jan 2020
  49. www.sciencedirect.com www.sciencedirect.com
    Thrombospondin-1 Mediates Axon Regeneration in Retinal Ganglion Cells
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.neuron.2019.05.044

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S0896627319304970
  50. www.sciencedirect.com www.sciencedirect.com
    Activity-dependent dendritic elaboration requires Pten
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:006440

      DOI: 10.1016/j.nbd.2019.104703

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S096999611930378X
  51. Nov 2018
  52. www.sciencedirect.com www.sciencedirect.com
    The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:006440

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1074761318304357
  53. www.sciencedirect.com www.sciencedirect.com
    Self-reinforcing effects of mTOR hyperactive neurons on dendritic growth
    1
    1. scibot 05 Nov 2018
      RRID: IMSR_JAX STRAIN #006440

      Curator: @bandrow

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    sciencedirect.com/science/article/pii/S0014488618305259
  54. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:006440

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    sciencedirect.com/science/article/pii/S2211124718314979
  55. www.sciencedirect.com www.sciencedirect.com
    EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:006440

      Curator: @anp055

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    sciencedirect.com/science/article/pii/S1535610818302290
  56. www.sciencedirect.com www.sciencedirect.com
    Myelination of Neuronal Cell Bodies when Myelin Supply Exceeds Axonal Demand
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:006440

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S0960982218302549
  57. Nov 2017
  58. www.sciencedirect.com www.sciencedirect.com
    PTEN deletion increases hippocampal granule cell excitability in male and female mice
    1
    1. scibot 08 Nov 2017
      JAX:006440

      Curator: @Jmenke

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      RRID:IMSR_JAX:006440 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0969996117302048