Hypothesis

20 Matching Annotations

Apr 2026
www.science.org www.science.org

Stem cell control in the lung by an autocrine injury-activated Igf complex

1
1. scibot 21 Apr 2026
  
  in Public
  
  JAX:006955
  
  DOI: 10.1126/science.adt1310
  
  Resource: (IMSR Cat# JAX_006955,RRID:IMSR_JAX:006955)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
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  RRID:IMSR_JAX:006955
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RRID:IMSR_JAX:006955

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scibot

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science.org/doi/10.1126/science.adt1310
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Brain insulin signaling restores deficits in striatal dopamine release in overweight male mice with preexisting low D2-receptor expression

1
1. scibot 12 Dec 2025
  
  in Public
  
  JAX:006955
  
  DOI: 10.1101/2025.10.28.685173
  
  Resource: (IMSR Cat# JAX_006955,RRID:IMSR_JAX:006955)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
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  RRID:IMSR_JAX:006955
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RRID:IMSR_JAX:006955

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12636313/
May 2025
www.sciencedirect.com www.sciencedirect.com

Insulin acts on astrocytes to shift their substrate preference to fatty acids

1
1. scibot 16 May 2025
  
  in Public
  
  Jax 006955
  
  DOI: 10.1016/j.isci.2024.111642
  
  Resource: (IMSR Cat# JAX_006955,RRID:IMSR_JAX:006955)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
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  RRID:IMSR_JAX:006955
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RRID:IMSR_JAX:006955

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scibot

URL

sciencedirect.com/science/article/pii/S2589004224028694
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

IGF1-dependent synaptic plasticity of mitral cells encodes olfactory memory during social learning

1
1. scibot 15 Nov 2024
  
  in Public
  
  006955
  
  DOI: 10.1016/j.neuron.2017.06.015
  
  Resource: (IMSR Cat# JAX_006955,RRID:IMSR_JAX:006955)
  
  Curator: @AleksanderDrozdz
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
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  RRID:IMSR_JAX:006955
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RRID:IMSR_JAX:006955

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC5559288/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cell-Specific Effects of Insulin in a Murine Model of Restenosis Under Insulin-Sensitive and Insulin-Resistant Conditions

1
1. scibot 30 Aug 2024
  
  in Public
  
  stock #006955
  
  DOI: 10.3390/cells13161387
  
  Resource: (IMSR Cat# JAX_006955,RRID:IMSR_JAX:006955)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
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  RRID:IMSR_JAX:006955
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RRID:IMSR_JAX:006955

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11352246/
Jul 2024
www.biorxiv.org www.biorxiv.org

IGF-1 Acts through Kiss1-expressing Cells to Influence Metabolism and Reproduction

1
1. scibot 12 Jul 2024
  
  in Public
  
  RRID:IMSR_JAX:006955
  
  DOI: 10.1101/2024.07.02.601722
  
  Resource: (IMSR Cat# JAX_006955,RRID:IMSR_JAX:006955)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
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  RRID:IMSR_JAX:006955
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RRID:IMSR_JAX:006955

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scibot

URL

biorxiv.org/content/10.1101/2024.07.02.601722v1
Jun 2024
www.sciencedirect.com www.sciencedirect.com

Insulin and leptin oscillations license food-entrained browning and metabolic flexibility

1
1. scibot 21 Jun 2024
  
  in Public
  
  RRID:IMSR_JAX:006955
  
  DOI: 10.1016/j.celrep.2024.114390
  
  Resource: (IMSR Cat# JAX_006955,RRID:IMSR_JAX:006955)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
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  RRID:IMSR_JAX:006955
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RRID:IMSR_JAX:006955

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724007186
May 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Normal Ovarian Function in Subfertile Mouse with Amhr2-Cre-Driven Ablation of Insr and Igf1r

1
1. scibot 21 May 2024
  
  in Public
  
  006955
  
  DOI: 10.3390/genes15050616
  
  Resource: (IMSR Cat# JAX_006955,RRID:IMSR_JAX:006955)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
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  RRID:IMSR_JAX:006955 DOI:10.3390/genes15050616
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RRID:IMSR_JAX:006955

DOI:10.3390/genes15050616

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11121541/
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection

1
1. scibot 11 Apr 2024
  
  in Public
  
  JAX:006955
  
  DOI: 10.1016/j.celrep.2024.114007
  
  Resource: (IMSR Cat# JAX_006955,RRID:IMSR_JAX:006955)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
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  RRID:IMSR_JAX:006955
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RRID:IMSR_JAX:006955

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724003358
Mar 2024
www.sciencedirect.com www.sciencedirect.com

Transketolase promotes MAFLD by limiting inosine-induced mitochondrial activity

1
1. scibot 28 Mar 2024
  
  in Public
  
  The Jackson LaboratoryCat#006955
  
  DOI: 10.1016/j.cmet.2024.03.003
  
  Resource: (IMSR Cat# JAX_006955,RRID:IMSR_JAX:006955)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
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  RRID:IMSR_JAX:006955
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RRID:IMSR_JAX:006955

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scibot

URL

sciencedirect.com/science/article/pii/S1550413124000822
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Insulin receptor loss impairs mammary tumorigenesis in mice

1
1. scibot 02 Nov 2023
  
  in Public
  
  RRID:IMSR_JAX:006955
  
  DOI: 10.1016/j.celrep.2023.113251
  
  Resource: (IMSR Cat# JAX_006955,RRID:IMSR_JAX:006955)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
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  RRID:IMSR_JAX:006955
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RRID:IMSR_JAX:006955

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scibot

URL

sciencedirect.com/science/article/pii/S2211124723012639
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Leptin and insulin do not exert redundant control of metabolic or emotive function via dopamine neurons

1
1. scibot 27 Jul 2021
  
  in Public
  
  006955
  
  DOI: 10.1016/j.yhbeh.2018.10.001
  
  Resource: (IMSR Cat# JAX_006955,RRID:IMSR_JAX:006955)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
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  RRID:IMSR_JAX:006955 RRIDCUR:Missing
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RRID:IMSR_JAX:006955

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S0018506X18301600
www.sciencedirect.com www.sciencedirect.com

Postnatal knockout of beta cell insulin receptor impaired insulin secretion in male mice exposed to high-fat diet stress

1
1. scibot 27 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX
  
  DOI: 10.1016/j.mce.2019.110588
  
  Resource: (IMSR Cat# JAX_006955,RRID:IMSR_JAX:006955)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
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  RRID:IMSR_JAX:006955 RRIDCUR:Unresolved
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RRID:IMSR_JAX:006955

RRIDCUR:Unresolved

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scibot

URL

sciencedirect.com/science/article/pii/S0303720719302904
Jan 2021
www.sciencedirect.com www.sciencedirect.com

Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution

1
1. scibot 22 Jan 2021
  
  in Public
  
  Stock No: 006955
  
  DOI: 10.1016/j.celrep.2020.108624
  
  Resource: (IMSR Cat# JAX_006955,RRID:IMSR_JAX:006955)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
  What is this?
  
  RRID:IMSR_JAX:006955 RRIDCUR:Missing
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RRID:IMSR_JAX:006955

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2211124720316132
Nov 2018
elifesciences.org elifesciences.org

Insulin regulates POMC neuronal plasticity to control glucose metabolism

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:006955
  
  Curator: @evieth
  
  Resource used:
  
  RRID:IMSR_JAX:006955
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:006955 RRIDCUR:Validated
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RRID:IMSR_JAX:006955

RRIDCUR:Validated

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scibot

URL

elifesciences.org/articles/38704
www.sciencedirect.com www.sciencedirect.com

Lipolysis Triggers a Systemic Insulin Response Essential for Efficient Energy Replenishment of Activated Brown Adipose Tissue in Mice

1
1. scibot 05 Nov 2018
  
  in Public
  
  006955
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:006955
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:006955 RRIDCUR:Missing
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RRID:IMSR_JAX:006955

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1550413118304029
www.sciencedirect.com www.sciencedirect.com

Insulin Receptor-Mediated Stimulation Boosts T Cell Immunity during Inflammation and Infection

1
1. scibot 05 Nov 2018
  
  in Public
  
  006955
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:006955
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:006955 RRIDCUR:Missing
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RRID:IMSR_JAX:006955

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1550413118305047
Nov 2017
www.sciencedirect.com www.sciencedirect.com

FGF21 Regulates Metabolism Through Adipose-Dependent and -Independent Mechanisms

1
1. scibot 08 Nov 2017
  
  in Public
  
  006955
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:006955
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:006955 RRIDCUR:Missing
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RRID:IMSR_JAX:006955

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1550413117301560
www.sciencedirect.com www.sciencedirect.com

A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:IMSR_JAX:006955
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:006955
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:006955 RRIDCUR:Validated
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RRID:IMSR_JAX:006955

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1550413117304345
www.sciencedirect.com www.sciencedirect.com

IGF1-Dependent Synaptic Plasticity of Mitral Cells in Olfactory Memory during Social Learning

1
1. scibot 08 Nov 2017
  
  in Public
  
  IR f/fJAX MiceStock No: 006955
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:006955
  
  SciCrunch record: RRID:IMSR_JAX:006955
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:006955 RRIDCUR:Missing
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RRID:IMSR_JAX:006955

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627317305135