30 Matching Annotations
  1. Aug 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Hepatic BMAL1 and HIF1α regulate a time-dependent hypoxic response and prevent hepatopulmonary-like syndrome
    1
    1. scibot 13 Aug 2024
      Jackson Laboratories007561

      DOI: 10.1016/j.cmet.2024.07.003

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      Curator: @vtello

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    sciencedirect.com/science/article/pii/S1550413124002742
  3. Jul 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vhl safeguards thymic epithelial cell identity and thymopoietic capacity by constraining Hif1a activity during development
    1
    1. scibot 26 Jul 2024
      RRID:IMSR_JAX:007561

      DOI: 10.1016/j.isci.2024.110258

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    ncbi.nlm.nih.gov/pmc/articles/PMC11261450/
  5. May 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Metabolic coordination between skin epithelium and type 17 immunity sustains chronic skin inflammation
    1
    1. scibot 21 May 2024
      RRID:IMSR_JAX:007561

      DOI: 10.1016/j.immuni.2024.04.022

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S1074761324002279
  7. Apr 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut
    1
    1. scibot 30 Apr 2024
      Jackson LaboratoryStrain# 007561

      DOI: 10.1016/j.immuni.2024.04.001

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @abever99

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    sciencedirect.com/science/article/pii/S1074761324002061
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Granulocytic myeloid-derived suppressor cell activity during biofilm infection is regulated by a glycolysis-HIF1a axis
    1
    1. scibot 18 Apr 2024
      RRID:IMSR_JAX:007561

      DOI: 10.1172/JCI174051

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @scibot

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014666/
  10. Mar 2024
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury
    1
    1. scibot 16 Mar 2024
      RRID:IMSR_JAX:007561

      DOI: 10.21203/rs.3.rs-3938716/v1

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      Curator: @scibot

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    pmc.ncbi.nlm.nih.gov/articles/PMC10925443/
  12. Jan 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Augmentation of scleral glycolysis promotes myopia through histone lactylation
    1
    1. scibot 19 Jan 2024
      Jackson LaboratoryStock No: 007561

      DOI: 10.1016/j.cmet.2023.12.023

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S1550413123004746
  14. Dec 2023
  15. www.sciencedirect.com www.sciencedirect.com
    IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis
    1
    1. scibot 02 Dec 2023
      RRID:IMSR_JAX:007561

      DOI: 10.1016/j.celrep.2023.113508

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      Curator: @scibot

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    sciencedirect.com/science/article/pii/S2211124723015206
  16. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Lactate produced by alveolar type II cells suppresses inflammatory alveolar macrophages in acute lung injury
    1
    1. scibot 01 Dec 2023
      RRID:IMSR_JAX:007561

      DOI: 10.1096/fj.202301722R

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      Curator: @scibot

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202301722R
  17. Oct 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease
    1
    1. scibot 13 Oct 2023
      RRID:IMSR_JAX:007561

      DOI: 10.1016/j.xcrm.2023.101236

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      Curator: @scibot

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    sciencedirect.com/science/article/pii/S2666379123004135
  19. Apr 2023
  20. www.sciencedirect.com www.sciencedirect.com
    A tissue injury sensing and repair pathway distinct from host pathogen defense
    1
    1. scibot 26 Apr 2023
      RRID:IMSR_JAX:007561

      DOI: 10.1016/j.cell.2023.03.031

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      Curator: @scibot

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    sciencedirect.com/science/article/pii/S0092867423003288
  21. Dec 2022
  22. www.sciencedirect.com www.sciencedirect.com
    Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells
    1
    1. scibot 08 Dec 2022
      JAX:007561

      DOI: 10.1016/j.cmet.2022.11.003

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S1550413122004946
  23. Apr 2022
  24. www.sciencedirect.com www.sciencedirect.com
    Stromal HIF2 Regulates Immune Suppression in the Pancreatic Cancer Microenvironment
    1
    1. scibot 08 Apr 2022
      RRID:IMSR_JAX:007561

      DOI: 10.1053/j.gastro.2022.02.024

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S0016508522001548
  25. Mar 2022
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The oxygen sensor prolyl hydroxylase domain 2 regulates the in vivo suppressive capacity of regulatory T cells
    1
    1. scibot 09 Mar 2022
      RRID:IMSR_JAX:007561

      DOI: 10.7554/eLife.70555

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @scibot

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    ncbi.nlm.nih.gov/pmc/articles/PMC8896828/
  27. Dec 2021
  28. www.sciencedirect.com www.sciencedirect.com
    Coenzyme A fuels T cell anti-tumor immunity
    1
    1. scibot 08 Dec 2021
      Stock#007561

      DOI: 10.1016/j.cmet.2021.11.010

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @Naa003

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      RRID:IMSR_JAX:007561 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1550413121005386
  29. Nov 2021
  30. www.sciencedirect.com www.sciencedirect.com
    Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction
    1
    1. scibot 11 Nov 2021
      Stock No: 007561

      DOI: 10.1016/j.stem.2021.10.009

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      Curator: @Naa003

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      RRIDCUR:Missing RRID:IMSR_JAX:007561
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    sciencedirect.com/science/article/pii/S1934590921004215
  31. Sep 2021
  32. www.sciencedirect.com www.sciencedirect.com
    Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming
    1
    1. scibot 24 Sep 2021
      Stock#007561

      DOI: 10.1016/j.cmet.2021.09.002

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @Naa003

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      RRIDCUR:Missing RRID:IMSR_JAX:007561
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    sciencedirect.com/science/article/pii/S1550413121004216
  33. Aug 2021
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HIF1α is required for NK cell metabolic adaptation during virus infection
    1
    1. scibot 27 Aug 2021
      RRID:IMSR_JAX:007561

      DOI: 10.7554/eLife.68484

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @scibot

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    ncbi.nlm.nih.gov/pmc/articles/PMC8382296/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 13 Aug 2021
      RRID:IMSR_JAX:007561

      DOI: 10.1016/j.celrep.2019.03.029

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @scibot

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    ncbi.nlm.nih.gov/pmc/articles/PMC6461402/
  36. Jul 2021
  37. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 31 Jul 2021
      RRID:IMSR_JAX:007561

      DOI: 10.1016/j.immuni.2019.01.021

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:IMSR_JAX:007561
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    sciencedirect.com/science/article/pii/S1074761319300445
  38. Jun 2021
  39. www.sciencedirect.com www.sciencedirect.com
    MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages
    1
    1. scibot 16 Jun 2021
      RRID:IMSR_JAX:007561

      DOI: 10.1016/j.celrep.2021.109264

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S2211124721006318
  40. May 2021
  41. www.sciencedirect.com www.sciencedirect.com
    Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity
    1
    1. scibot 06 May 2021
      RRID:IMSR_JAX:007561

      DOI: 10.1016/j.immuni.2020.05.001

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    sciencedirect.com/science/article/pii/S1074761320301825
  42. Apr 2021
  43. www.sciencedirect.com www.sciencedirect.com
    Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy
    1
    1. scibot 24 Apr 2021
      JAX:007561

      DOI: 10.1016/j.cell.2020.06.014

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    sciencedirect.com/science/article/pii/S0092867420307455
  44. Mar 2021
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stage-dependent effects of intermittent hypoxia influence the outcome of hippocampal adult neurogenesis
    1
    1. scibot 21 Mar 2021
      RRID:IMSR_JAX:007

      DOI: 10.1038/s41598-021-85357-5

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @evieth

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      RRIDCUR:SyntaxError RRIDCUR:Unresolved RRID:IMSR_JAX:007561
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    ncbi.nlm.nih.gov/pmc/articles/PMC7966401/
  46. Jan 2021
  47. www.jneurosci.org www.jneurosci.org
    HIFα regulates developmental myelination independent of autocrine Wnt signaling
    1
    1. scibot 29 Jan 2021
      RRID:IMSR_JAX:007561

      DOI: 10.1523/JNEUROSCI.0731-20.2020

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @Naa003

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    jneurosci.org/content/41/2/251
  48. Sep 2020
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bmal1 integrates mitochondrial metabolism and macrophage activation
    1
    1. scibot 05 Sep 2020
      JAX:007561

      DOI: 10.7554/eLife.54090

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      Curator: @evieth

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      RRIDCUR:Validated RRID:IMSR_JAX:007561
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    ncbi.nlm.nih.gov/pmc/articles/PMC7259948/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways
    1
    1. scibot 03 Sep 2020
      RRID: IMSR_JAX:007561

      DOI: 10.1038/s41467-020-15656-4

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC7181614/
  51. www.sciencedirect.com www.sciencedirect.com
    Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration
    1
    1. scibot 03 Sep 2020
      Hi1faflox/flox

      DOI: 10.1016/j.stem.2020.06.020

      Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)

      Curator: @Naa003

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      Curator comments: B6.129-Hif1atm3Rsjo/J Mus musculus IMSR Cat# JAX:007561

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      RRID:IMSR_JAX:007561 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1934590920302873
  52. Jan 2020
  53. www.sciencedirect.com www.sciencedirect.com
    A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:007561

      DOI: 10.1016/j.immuni.2019.03.001

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      Curator: @ethanbadger

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      RRID:IMSR_JAX:007561 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761319300913
  54. Nov 2018
  55. www.sciencedirect.com www.sciencedirect.com
    PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism
    1
    1. scibot 05 Nov 2018
      007561

      Curator: @Jmenke

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      RRID:IMSR_JAX:007561 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1534580718305975