30 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints
    1
    1. scibot 07 Nov 2024
      008169

      DOI: 10.1038/s41590-023-01627-6

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @AleksanderDrozdz

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    pmc.ncbi.nlm.nih.gov/articles/PMC10863749/
  3. Oct 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model
    1
    1. scibot 02 Oct 2024
      RRID:IMSR_JAX:008169

      DOI: 10.1016/j.neuron.2024.09.006

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S0896627324006548
  5. Sep 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Failure in a population: Tauopathy disrupts homeostatic set-points in emergent dynamics despite stability in the constituent neurons
    1
    1. scibot 06 Sep 2024
      008169

      DOI: 10.1016/j.neuron.2024.08.006

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @vtello

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    sciencedirect.com/science/article/pii/S0896627324005786
  7. Jul 2024
  8. pubs.aip.org pubs.aip.org
    Auditory brainstem response audiometry in tauopathy mouse model of human Alzheimer's disease
    1
    1. scibot 16 Jul 2024
      RRID:IMSR_JAX:008169

      DOI: 10.1121/10.0026602

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      Curator: @scibot

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    pubs.aip.org/asa/jel/article/4/7/071201/3302688/Auditory-brainstem-response-audiometry-in
  9. May 2024
  10. www.biorxiv.org www.biorxiv.org
    Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model
    1
    1. scibot 10 May 2024
      RRID:IMSR_JAX:008169

      DOI: 10.1101/2024.01.24.577107

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @scibot

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    biorxiv.org/content/10.1101/2024.01.24.577107v1
  11. Apr 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Human iPSC 4R tauopathy model uncovers modifiers of tau propagation
    1
    1. scibot 09 Apr 2024
      008169

      DOI: 10.1016/j.cell.2024.03.015

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @abever99

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    sciencedirect.com/science/article/pii/S0092867424003064
  13. Mar 2024
  14. www.sciencedirect.com www.sciencedirect.com
    P-tau217 correlates with neurodegeneration in Alzheimer’s disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy
    2
    1. scibot 21 Mar 2024
      RRID:IMSR_JAX:008169

      DOI: 10.1016/j.neuron.2024.02.017

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      Curator: @scibot

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      RRID:IMSR_JAX:008169
    2. scibot 21 Mar 2024
      RRID:IMSR_JAX:008169

      DOI: 10.1016/j.neuron.2024.02.017

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      Curator: @scibot

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    sciencedirect.com/science/article/pii/S0896627324001272
  15. Feb 2024
  16. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Perineuronal net deglycosylation associates with tauopathy-induced gliosis and neurodegeneration
    1
    1. scibot 10 Feb 2024
      RRID:IMSR_JAX:008169

      DOI: 10.1111/jnc.16067

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @scibot

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16067
  17. Jan 2024
  18. www.science.org www.science.org
    TRIM11 protects against tauopathies and is down-regulated in Alzheimer’s disease
    1
    1. scibot 03 Jan 2024
      008169

      DOI: 10.1126/science.add6696

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @bandrow

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    science.org/doi/10.1126/science.add6696
  19. Nov 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist
    1
    1. scibot 28 Nov 2023
      RRID:IMSR_JAX:008169

      DOI: 10.1016/j.neuron.2023.10.023

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      Curator: @scibot

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    sciencedirect.com/science/article/pii/S0896627323008048
  21. www.sciencedirect.com www.sciencedirect.com
    Skeletal muscle TFEB signaling promotes central nervous system function and reduces neuroinflammation during aging and neurodegenerative disease
    1
    1. scibot 17 Nov 2023
      JAX:008169

      DOI: 10.1016/j.celrep.2023.113436

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S2211124723014481
  22. Jun 2023
  23. www.sciencedirect.com www.sciencedirect.com
    An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology
    1
    1. scibot 23 Jun 2023
      RRID:IMSR_JAX:008169

      DOI: 10.1016/j.neuron.2023.05.006

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S0896627323003793
  24. Nov 2022
  25. www.sciencedirect.com www.sciencedirect.com
    TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4
    1
    1. scibot 11 Nov 2022
      RRID:IMSR_JAX:008169

      DOI: 10.1016/j.neuron.2022.10.022

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S0896627322009552
  26. Oct 2022
  27. www.cell.com www.cell.com
    X-linked ubiquitin-specific peptidase 11 increases tauopathy vulnerability in women
    1
    1. scibot 05 Oct 2022
      RRID:IMSR_JAX:008

      DOI: 10.1016/j.cell.2022.09.002

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @a5munoz

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      RRID:IMSR_JAX:008169 RRIDCUR:Unresolved
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    cell.com/cell/fulltext/S0092-8674(22)01124-2
  28. Aug 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Disruption of nuclear envelope integrity as a possible initiating event in tauopathies
    1
    1. scibot 26 Aug 2022
      RRID:IMSR_JAX:008169

      DOI: 10.1016/j.celrep.2022.111249

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S2211124722010671
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Alterations in a cross-hemispheric circuit associates with novelty discrimination deficits in mouse models of neurodegeneration
    1
    1. scibot 22 Aug 2022
      Jackson LabsStock#008169

      DOI: 10.1016/j.neuron.2022.07.023

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @sophiastull

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    pmc.ncbi.nlm.nih.gov/articles/PMC9547933/
  31. May 2022
  32. link.springer.com link.springer.com
    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
    1
    1. scibot 05 May 2022
      RRID:IMSR_JAX:008169

      DOI: 10.1186/s13024-022-00526-y

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @scibot

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    link.springer.com/article/10.1186/s13024-022-00526-y
  33. Aug 2021
  34. www.sciencedirect.com www.sciencedirect.com
    Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy
    1
    1. scibot 28 Aug 2021
      stock# 008169

      DOI: 10.1016/j.molcel.2021.07.038

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @Naa003

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      RRID:IMSR_JAX:008169 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1097276521006225
  35. Jul 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer’s Disease
    1
    1. scibot 30 Jul 2021
      JAX:008169

      DOI: 10.1016/j.neuron.2018.10.031

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @Jmenke

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      RRIDCUR:Validated RRID:IMSR_JAX:008169
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    sciencedirect.com/science/article/pii/S0896627318309395
  37. Jun 2021
  38. www.sciencedirect.com www.sciencedirect.com
    Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms
    1
    1. scibot 22 Jun 2021
      Cat# 008169

      DOI: 10.1016/j.neuron.2021.05.034

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @Naa003

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      RRID:IMSR_JAX:008169 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S089662732100413X
  39. May 2021
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction
    1
    1. scibot 27 May 2021
      008169

      DOI: 10.7554/eLife.65301

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @Naa003

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      RRID:IMSR_JAX:008169 RRIDCUR:Missing
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    ncbi.nlm.nih.gov/pmc/articles/PMC8139826/
  41. Apr 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome
    1
    1. scibot 23 Apr 2021
      RRID:IMSR_JAX:008169

      DOI: 10.1016/j.cell.2021.03.048

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      Curator: @Naa003

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      RRID:IMSR_JAX:008169 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867421003792
  43. www.sciencedirect.com www.sciencedirect.com
    Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia
    1
    1. scibot 09 Apr 2021
      RRID:IMSR_JAX:008169

      DOI: 10.1016/j.neuron.2021.03.024

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:IMSR_JAX:008169
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    sciencedirect.com/science/article/pii/S089662732100194X
  44. Jan 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation
    1
    1. scibot 20 Jan 2021
      RRID:IMSR_JAX:008169

      DOI: 10.1016/j.neuron.2020.12.016

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @Naa003

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      RRID:IMSR_JAX:008169 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627320309983
  46. Sep 2020
  47. www.sciencedirect.com www.sciencedirect.com
    SEQUIN Multiscale Imaging of Mammalian Central Synapses Reveals Loss of Synaptic Connectivity Resulting from Diffuse Traumatic Brain Injury
    1
    1. scibot 12 Sep 2020
      RRID:IMSR_JAX:008169

      DOI: 10.1016/j.neuron.2020.04.012

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:008169 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627320302816
  48. link.springer.com link.springer.com
    Fyn kinase inhibition reduces protein aggregation, increases synapse density and improves memory in transgenic and traumatic Tauopathy
    1
    1. scibot 11 Sep 2020
      RRID:IMSR_JAX:008169

      DOI: 10.1186/s40478-020-00976-9

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:IMSR_JAX:008169
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    link.springer.com/article/10.1186/s40478-020-00976-9
  49. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Amyloidosis is associated with thicker myelin and increased oligodendrogenesis in the adult mouse brain
    1
    1. scibot 03 Sep 2020
      RRID:IMSR_JAX:008169

      DOI: 10.1002/jnr.24672

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:IMSR_JAX:008169
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24672
  50. Jan 2020
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysregulation of RNA Splicing in Tauopathies
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:008169

      DOI: 10.1016/j.celrep.2019.11.093

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:008169 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6941411/
  52. www.sciencedirect.com www.sciencedirect.com
    Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer’s Disease
    1
    1. scibot 13 Jan 2020
      JAX:008169

      DOI: 10.1016/j.neuron.2018.10.031

      Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)

      Curator: @Jmenke

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      RRID:IMSR_JAX:008169 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627318309395