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133 Matching Annotations

Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RORγt Inhibition Reduces Pro-Tumor Inflammation and Decreases Tumor Growth in Experimental Models of Lung Cancer

1
1. scibot 03 Mar 2026
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/2326-6066.CIR-24-1128
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12288671/
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Netrin-1 Promotes Pancreatic Tumorigenesis and Innervation through NEO1

1
1. scibot 11 Feb 2026
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/0008-5472.CAN-25-2243
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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pmc.ncbi.nlm.nih.gov/articles/PMC12885529/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Immune Stromal Components Impede Biological Effectiveness of Carbon Ion Therapy in a Preclinical Model of Pancreatic Ductal Adenocarcinoma

1
1. scibot 07 Feb 2026
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/1535-7163.MCT-25-0501
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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pmc.ncbi.nlm.nih.gov/articles/PMC12869159/
Jan 2026
www.science.org www.science.org

Aberrant methylation limits antitumoral inflammation in lung adenocarcinoma by restricting RIPK3 expression

1
1. scibot 27 Jan 2026
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1126/sciadv.adz9227
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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science.org/doi/10.1126/sciadv.adz9227
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Intrinsic resistance to RAS inhibitors is driven by dysregulation of KRAS degradation

1
1. scibot 16 Jan 2026
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1038/s41467-025-67109-5
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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pmc.ncbi.nlm.nih.gov/articles/PMC12796258/
www.sciencedirect.com www.sciencedirect.com

MITA/STING-driven CD38 induction in Siglec-Flow macrophages promotes regulatory T cell survival and non-small cell lung cancer progression

1
1. scibot 13 Jan 2026
  
  in Public
  
  The Jackson LaboratoryStrain# 008179
  
  DOI: 10.1016/j.devcel.2025.12.007
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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sciencedirect.com/science/article/pii/S1534580725007683
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SMURF2 facilitates GAP17 Isoform 1 membrane displacement to promote mutant p53-KRAS oncogenic synergy

1
1. scibot 06 Dec 2025
  
  in Public
  
  JAX:008179
  
  DOI: 10.1158/1541-7786.MCR-24-0701
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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pmc.ncbi.nlm.nih.gov/articles/PMC12133423/
Nov 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Protein kinase Cι dictates tumor trajectory, cell plasticity, and immune surveillance in lung adenocarcinoma

1
1. scibot 29 Nov 2025
  
  in Public
  
  The Jackson Laboratory008179
  
  DOI: 10.1016/j.celrep.2025.116606
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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sciencedirect.com:5037/science/article/pii/S2211124725013786
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Functional mapping of epigenomic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes

1
1. scibot 23 Nov 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/2159-8290.CD-24-1565
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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pmc.ncbi.nlm.nih.gov/articles/PMC12469823/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

EML4-ALK variant-specific genetic interactions shape lung tumorigenesis

1
1. scibot 23 Nov 2025
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/2159-8290.CD-24-1417
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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pmc.ncbi.nlm.nih.gov/articles/PMC12479099/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Aging represses oncogenic KRAS-driven lung tumorigenesis and alters tumor suppression

1
1. scibot 18 Nov 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1038/s43587-025-00986-z
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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pmc.ncbi.nlm.nih.gov/articles/PMC12616358/
www.sciencedirect.com www.sciencedirect.com

Injury and inflammation promote cancer progression at the anorectal junction

1
1. scibot 16 Nov 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.celrep.2025.116552
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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sciencedirect.com/science/article/pii/S2211124725013233
www.sciencedirect.com www.sciencedirect.com

Senolytic-sensitive p16Ink4a+ fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity

1
1. scibot 05 Nov 2025
  
  in Public
  
  Jackson LaboratoryJAX# 008179
  
  DOI: 10.1016/j.stem.2025.10.005
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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sciencedirect.com/science/article/pii/S193459092500373X
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models

1
1. scibot 01 Nov 2025
  
  in Public
  
  RRID: IMSR_JAX:008179
  
  DOI: 10.1158/2767-9764.CRC-25-0279
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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pmc.ncbi.nlm.nih.gov/articles/PMC12569591/
Oct 2025
www.sciencedirect.com www.sciencedirect.com

Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas

1
1. scibot 30 Oct 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.celrep.2025.116487
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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sciencedirect.com/science/article/pii/S2211124725012586
www.sciencedirect.com www.sciencedirect.com

Distinct T cell functions enable efficient immunoediting and prevent tumor emergence of developing sarcomas

1
1. scibot 08 Oct 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.ccell.2025.09.005
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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sciencedirect.com/science/article/pii/S1535610825003976
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Loss of Sorting Nexin 10 accelerates KRAS-induced pancreatic tumorigenesis

1
1. scibot 11 Sep 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/2767-9764.CRC-25-0168
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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pmc.ncbi.nlm.nih.gov/articles/PMC12415682/
www.sciencedirect.com www.sciencedirect.com

A pathological role of O-GlcNAcylation-driven TR11B production and function in lung adenocarcinoma

1
1. scibot 11 Sep 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.devcel.2025.08.010
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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RRID:IMSR_JAX:008179

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sciencedirect.com/science/article/pii/S1534580725005301
www.sciencedirect.com www.sciencedirect.com

Early adipose tissue wasting in a preclinical model of human lung cancer cachexia

1
1. scibot 11 Sep 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.celrep.2025.116278
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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sciencedirect.com/science/article/pii/S2211124725010496
Aug 2025
www.biorxiv.org www.biorxiv.org

L1CAM signaling through planar cell polarity generates SOX2+ metastatic progenitors in lung adenocarcinoma

1
1. scibot 27 Aug 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1101/2025.08.22.671773
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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biorxiv.org/content/10.1101/2025.08.22.671773v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A RAS(ON) Multi-Selective Inhibitor Combination Therapy Triggers Long-term Tumor Control through Senescence-Associated Tumor-Immune Equilibrium in Pancreatic Ductal Adenocarcinoma

1
1. scibot 06 Aug 2025
  
  in Public
  
  IMSR_JAX:008179
  
  DOI: 10.1158/2159-8290.CD-24-1425
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @sonofthor
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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RRID:IMSR_JAX:008179

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12319406/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Early adipose tissue wasting in a novel preclinical model of human lung cancer cachexia

1
1. scibot 15 Jul 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1101/2024.09.27.615385
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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pmc.ncbi.nlm.nih.gov/articles/PMC11623500/
Jun 2025
www.sciencedirect.com www.sciencedirect.com

Protocol for adeno-associated virus-mediated gene delivery to accelerate pancreatic carcinogenesis in mice

1
1. scibot 21 Jun 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.xpro.2025.103907
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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sciencedirect.com/science/article/pii/S2666166725003132
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FGFR2 Abrogation Intercepts Pancreatic Ductal Adenocarcinoma Development

1
1. scibot 18 Jun 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/0008-5472.CAN-24-4576
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12169444/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A STAG2-PAXIP1/PAGR1 axis suppresses lung tumorigenesis

1
1. scibot 11 Jun 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1084/jem.20240765
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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pmc.ncbi.nlm.nih.gov/articles/PMC11627241/
May 2025
www.sciencedirect.com www.sciencedirect.com

Regulatory network analysis of Dclk1 gene expression reveals a tuft cell-ILC2 axis that inhibits pancreatic tumor progression

1
1. scibot 29 May 2025
  
  in Public
  
  The Jackson LaboratoryStock No: 008179
  
  DOI: 10.1016/j.celrep.2025.115734
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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sciencedirect.com/science/article/pii/S2211124725005054
www.sciencedirect.com www.sciencedirect.com

Distinct Roles for the Thioredoxin and Glutathione Antioxidant Systems in Nrf2-Mediated Lung Tumor Initiation and Progression

1
1. scibot 16 May 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.redox.2025.103653
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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sciencedirect.com/science/article/pii/S2213231725001661
Apr 2025
www.sciencedirect.com www.sciencedirect.com

Histamine 1 Receptor (HRH1): A potential therapeutic target for Pancreatic Ductal Adenocarcinoma

1
1. scibot 08 Apr 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.jpet.2025.103573
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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sciencedirect.com/science/article/pii/S0022356525397867
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 04 Apr 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/0008-5472.can-24-4576
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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52.53.155.43/d82b50f0340a265ea39586fdf6016ce1aa48cfa1/PDF-html.html
Mar 2025
52.53.155.43 52.53.155.43

1-s2.0-S258900422500536X-main-html.html

2
1. scibot 29 Mar 2025
  
  in Public
  
  Jackson Laboratory [JAX] stock No. 008179
  
  DOI: 10.1016/j.isci.2025.112275
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
2. scibot 29 Mar 2025
  
  in Public
  
  Jackson Laboratory [JAX] stock No. 008179
  
  DOI: 10.1016/j.isci.2025.112275
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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52.53.155.43/20fb93250db4f2d7fdfa7182e1f229b229b7142f/1-s2.0-S258900422500536X-main-html.html
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Combinatorial In Vivo Genome Editing Identifies Widespread Epistasis and an Accessible Fitness Landscape During Lung Tumorigenesis

1
1. scibot 15 Feb 2025
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1093/molbev/msaf023
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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pmc.ncbi.nlm.nih.gov/articles/PMC11824425/
www.sciencedirect.com www.sciencedirect.com

KRAS4B oncogenic mutants promote non-small cell lung cancer progression via the interaction of deubiquitinase USP25 with RNF31

1
1. scibot 14 Feb 2025
  
  in Public
  
  The Jackson LaboratoryStrain# 008179
  
  DOI: 10.1016/j.devcel.2025.01.015
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179
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sciencedirect.com/science/article/pii/S1534580725000358
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Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis

1
1. scibot 13 Feb 2025
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/0008-5472.CAN-23-3419
  
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aacrjournals.org/cancerres/article/84/18/2968/747793/Scribble-Deficiency-Promotes-Pancreatic-Ductal
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Disrupting AGR2/IGF1 paracrine and reciprocal signaling for pancreatic cancer therapy

1
1. scibot 07 Feb 2025
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.xcrm.2024.101927
  
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sciencedirect.com/science/article/pii/S2666379124006980
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Imaging NRF2 activation in non-small cell lung cancer with positron emission tomography

1
1. scibot 20 Dec 2024
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1038/s41467-024-54852-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11652680/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors

1
1. scibot 17 Dec 2024
  
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  JAX:008179
  
  DOI: 10.1016/j.devcel.2017.02.006
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5517315/
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FAK loss reduces BRAFV600E-induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation

1
1. scibot 14 Nov 2024
  
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  008179
  
  DOI: 10.21203/rs.3.rs-2531119/v2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9915899/
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A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression

1
1. scibot 11 Nov 2024
  
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  Strain# 008179
  
  DOI: 10.1016/j.devcel.2024.10.010
  
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Sep 2024
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A STAG2-PAXIP1/PAGR1 axis suppresses lung tumorigenesis

1
1. scibot 28 Sep 2024
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1101/2024.09.14.613043
  
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biorxiv.org/content/10.1101/2024.09.14.613043v1
Aug 2024
www.biorxiv.org www.biorxiv.org

Functional mapping of epigenetic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes

1
1. scibot 25 Aug 2024
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1101/2024.08.19.607671
  
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FRA1 controls acinar cell plasticity during murine KrasG12D-induced pancreatic acinar to ductal metaplasia

1
1. scibot 23 Aug 2024
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.devcel.2024.07.021
  
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2
1. scibot 02 Aug 2024
  
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  008179
  
  DOI: 10.21203/rs.3.rs-2531119/v1
  
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  Curator: @bandrow
  
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2. scibot 02 Aug 2024
  
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  008179
  
  DOI: 10.21203/rs.3.rs-2531119/v1
  
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researchsquare.com/article/rs-7216019/'https://www.researchsquare.com/article/rs-7216019/v1
Jul 2024
www.science.org www.science.org

Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer

1
1. scibot 25 Jul 2024
  
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  RRID: IMSR_JAX:008179
  
  DOI: 10.1126/science.adh4567
  
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  Curator: @dhovakimyan1
  
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52.53.155.43 52.53.155.43

Cancer-associated endocrine cells participate in pancreatic carcinogenesis

1
1. scibot 25 Jul 2024
  
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  Cat#008179
  
  DOI: 10.1053/j.gastro.2024.07.016
  
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52.53.155.43/00ed7388bef43fd34d4811e77f0e00ce1748f907/1-s2.0-S0016508524052259-main-html.html
Jun 2024
www.biorxiv.org www.biorxiv.org

Aging represses lung tumorigenesis and alters tumor suppression

1
1. scibot 04 Jun 2024
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1101/2024.05.28.596319
  
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biorxiv.org/content/10.1101/2024.05.28.596319v1
May 2024
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CRACD loss induces neuroendocrine cell plasticity of lung adenocarcinoma

1
1. scibot 30 May 2024
  
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  JAX:008179
  
  DOI: 10.1016/j.celrep.2024.114286
  
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sciencedirect.com/science/article/pii/S2211124724006144
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Expression of the membrane tetraspanin claudin 18 on cancer cells promotes T lymphocyte infiltration and antitumor immunity in pancreatic cancer

1
1. scibot 16 May 2024
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.immuni.2024.04.021
  
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sciencedirect.com/science/article/pii/S1074761324002267
Apr 2024
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The UBE2F-CRL5ASB11-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells

1
1. scibot 04 Apr 2024
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.devcel.2024.03.018
  
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sciencedirect.com/science/article/pii/S1534580724001837
Mar 2024
www.biorxiv.org www.biorxiv.org

Modeling the genomic complexity of human cancer using Cas12a mice

1
1. scibot 15 Mar 2024
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1101/2024.03.07.583774
  
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  Curator: @mzhang007
  
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biorxiv.org/content/10.1101/2024.03.07.583774v1
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Combinatorial in vivo genome editing identifies widespread epistasis during lung tumorigenesis

1
1. scibot 15 Mar 2024
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1101/2024.03.07.583981
  
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biorxiv.org/content/10.1101/2024.03.07.583981v1
Feb 2024
aacrjournals.org aacrjournals.org

Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma

2
1. scibot 23 Feb 2024
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/1078-0432.CCR-23-1143
  
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2. scibot 23 Feb 2024
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/1078-0432.CCR-23-1143
  
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aacrjournals.org/clincancerres/article/29/24/5183/731660/Nuclear-GRP78-Promotes-Metabolic-Reprogramming-and
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Exosomes define a local and systemic communication network in healthy pancreas and pancreatic ductal adenocarcinoma

1
1. scibot 22 Feb 2024
  
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  JAX:008179
  
  DOI: 10.1038/s41467-024-45753-7
  
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link.springer.com/article/10.1038/s41467-024-45753-7
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state

1
1. scibot 30 Jan 2024
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1038/s41419-024-06460-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10810848/
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Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

2
1. scibot 04 Jan 2024
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.devcel.2023.07.025
  
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2. scibot 04 Jan 2024
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.devcel.2023.07.025
  
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sciencedirect.com/science/article/pii/S1534580723003945
Dec 2023
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A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas

1
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.devcel.2023.11.008
  
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52.53.155.43 52.53.155.43

ccr-23-1143-html.html

1
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/1078-0432.ccr-23-1143
  
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52.53.155.43/aa509a782208f9df8c6754b69c5c07021388a9c4/ccr-23-1143-html.html
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Novel tumor organoid-based mouse model to study image-guided radiation therapy of rectal cancer after non-invasive and precise endoscopic implantation

1
1. scibot 27 Oct 2023
  
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  JAX:008179
  
  DOI: 10.1016/j.ijrobp.2023.10.008
  
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sciencedirect.com/science/article/pii/S0360301623080148
www.nature.com www.nature.com

Decreased liver B vitamin-related enzymes as a metabolic hallmark of cancer cachexia

1
1. scibot 07 Oct 2023
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1038/s41467-023-41952-w
  
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nature.com/articles/s41467-023-41952-w
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression

1
1. scibot 31 Aug 2023
  
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  JAX:008179
  
  DOI: 10.1186/s12967-023-04448-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10463307/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development

1
1. scibot 12 Aug 2023
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.isci.2023.107368
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10407955/
Jun 2023
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Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression

1
1. scibot 17 Jun 2023
  
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  DOI: 10.1158/0008-5472.CAN-22-3848
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10267679/
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Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion

1
1. scibot 02 Jun 2023
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.stem.2023.05.005
  
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sciencedirect.com/science/article/pii/S1934590923001753
www.cell.com www.cell.com

Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer

1
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.ccell.2023.05.004
  
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cell.com/cancer-cell/fulltext/S1535-6108(23)00172-1
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Gender-specific changes of the gut microbiome correlate with tumor development in murine models of pancreatic cancer

1
1. scibot 31 May 2023
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.isci.2023.106841
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10225934/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors

1
1. scibot 04 May 2023
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/0008-5472.CAN-22-3000
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10152234/
Mar 2023
www.nature.com www.nature.com

Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth

1
1. scibot 01 Mar 2023
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1038/s41556-022-01049-w
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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nature.com/articles/s41556-022-01049-w
Dec 2022
www.sciencedirect.com www.sciencedirect.com

The Sag-Shoc2 axis regulates conversion of mPanINs to cystic lesions in Kras pancreatic tumor model

1
1. scibot 24 Dec 2022
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.celrep.2022.111837
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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sciencedirect.com/science/article/pii/S2211124722017296
Nov 2022
aacrjournals.org aacrjournals.org

The cAMP/PKA/CREB and TGF-β/SMAD4 pathways regulate stemness and metastatic potential in colorectal cancer cells

1
1. scibot 22 Nov 2022
  
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  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/0008-5472.CAN-22-1369
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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aacrjournals.org/cancerres/article/82/22/4179/710134/The-cAMP-PKA-CREB-and-TGF-SMAD4-Pathways-Regulate
Oct 2022
52.53.155.43 52.53.155.43

can-22-1369-html.html

1
1. scibot 27 Oct 2022
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/0008-5472.can-22-1369
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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52.53.155.43/73ac479c11a5b7254565d9c8982a4bd5bdf3415d/can-22-1369-html.html
www.sciencedirect.com www.sciencedirect.com

The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes

1
1. scibot 09 Oct 2022
  
  in Public
  
  008179
  
  DOI: 10.1016/j.cell.2022.09.020
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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sciencedirect.com/science/article/pii/S0092867422011928
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression

1
1. scibot 22 Sep 2022
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1136/gutjnl-2021-324994
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9271144/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma

1
1. scibot 02 Sep 2022
  
  in Public
  
  RRID:IMSR_JAX
  
  DOI: 10.1158/2159-8290.CD-21-1077
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @evieth
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Unresolved
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ncbi.nlm.nih.gov/pmc/articles/PMC8904298/
Aug 2022
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Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma

1
1. scibot 31 Aug 2022
  
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  JAX:008179
  
  DOI: 10.1016/j.celrep.2022.111253
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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sciencedirect.com/science/article/pii/S2211124722010713
Jun 2022
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Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis

1
1. scibot 25 Jun 2022
  
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  JAX:008179
  
  DOI: 10.1016/j.molcel.2022.06.005
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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sciencedirect.com/science/article/pii/S109727652200541X
rupress.org rupress.org

CD4+ T helper 2 cells suppress breast cancer by inducing terminal differentiation

1
1. scibot 07 Jun 2022
  
  in Public
  
  JAX:008179
  
  DOI: 10.1084/jem.20201963
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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rupress.org/jem/article/219/7/e20201963/213261/CD4-T-helper-2-cells-suppress-breast-cancer-by
May 2022
www.sciencedirect.com www.sciencedirect.com

ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer

1
1. scibot 05 May 2022
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.devcel.2022.04.014
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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sciencedirect.com/science/article/pii/S1534580722002544
Mar 2022
www.nature.com www.nature.com

CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver

1
1. scibot 23 Mar 2022
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1038/s41596-021-00677-0
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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nature.com/articles/s41596-021-00677-0
Feb 2022
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Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer

1
1. scibot 04 Feb 2022
  
  in Public
  
  JAX:008179
  
  DOI: 10.1016/j.ccell.2022.01.003
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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sciencedirect.com/science/article/pii/S1535610822000058
Jan 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A functional taxonomy of tumor suppression in oncogenic KRAS-driven lung cancer

1
1. scibot 05 Jan 2022
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/2159-8290.CD-20-1325
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8292166/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Bacterial-driven inflammation and mutant BRAF expression combine to promote murine colon tumorigenesis that is sensitive to immune checkpoint therapy

1
1. scibot 03 Jan 2022
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/2159-8290.CD-20-0770
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8295175/
Dec 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A new murine esophageal organoid culture method and organoid-based model of esophageal squamous cell neoplasia

1
1. scibot 11 Dec 2021
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.isci.2021.103440
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8633967/
Nov 2021
www.sciencedirect.com www.sciencedirect.com

Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice

1
1. scibot 12 Nov 2021
  
  in Public
  
  Stock No: 008179
  
  DOI: 10.1016/j.xcrm.2021.100434
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @Naa003
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2666379121002962
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Glut1 expression in tumor-associated neutrophils promotes lung cancer growth and resistance to radiotherapy

1
1. scibot 05 Nov 2021
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/0008-5472.CAN-20-2870
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8137580/
Oct 2021
www.sciencedirect.com www.sciencedirect.com

Glycogen accumulation and phase separation drives liver tumor initiation

1
1. scibot 22 Oct 2021
  
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  Stock No: 008179
  
  DOI: 10.1016/j.cell.2021.10.001
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S0092867421011752
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors

1
1. scibot 24 Sep 2021
  
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  Stock No: 008179
  
  DOI: 10.1016/j.cell.2021.08.020
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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  RRIDCUR:Missing RRID:IMSR_JAX:008179
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sciencedirect.com/science/article/pii/S0092867421009946
www.sciencedirect.com www.sciencedirect.com

NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis

1
1. scibot 23 Sep 2021
  
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  JAX 008179
  
  DOI: 10.1016/j.molcel.2021.08.034
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1097276521007140
www.sciencedirect.com www.sciencedirect.com

Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging

1
1. scibot 21 Sep 2021
  
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  Stock# 008179
  
  DOI: 10.1016/j.celrep.2021.109689
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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sciencedirect.com/science/article/pii/S2211124721011360
www.sciencedirect.com www.sciencedirect.com

Conventional type I dendric cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes

1
1. scibot 17 Sep 2021
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.immuni.2021.08.026
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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sciencedirect.com/science/article/pii/S1074761321003605
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy

1
1. scibot 16 Aug 2021
  
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  JAX:008179
  
  DOI: 10.1016/j.cell.2021.07.020
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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sciencedirect.com/science/article/pii/S0092867421008795
Jul 2021
www.sciencedirect.com www.sciencedirect.com

p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

1
1. scibot 31 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.ccell.2019.01.006
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819300406
www.sciencedirect.com www.sciencedirect.com

Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.devcel.2018.11.001
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @Jmenke
  
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  RRIDCUR:Validated RRID:IMSR_JAX:008179
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sciencedirect.com/science/article/pii/S1534580718309195
www.sciencedirect.com www.sciencedirect.com

Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma

1
1. scibot 29 Jul 2021
  
  in Public
  
  The Jackson Laboratory008179
  
  DOI: 10.1016/j.ccell.2019.07.002
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Unrecognized
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sciencedirect.com/science/article/pii/S1535610819303290
www.sciencedirect.com www.sciencedirect.com

p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas

1
1. scibot 29 Jul 2021
  
  in Public
  
  Mouse strain: B6.129S4-Krastm4Tyj/J
  
  DOI: 10.1016/j.celrep.2019.07.027
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124719309246
www.sciencedirect.com www.sciencedirect.com

A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis

1
1. scibot 27 Jul 2021
  
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  RRID:IMSR_008179
  
  DOI: 10.1016/j.ccell.2018.10.004
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @bandrow
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Unresolved RRIDCUR:SyntaxError
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sciencedirect.com/science/article/pii/S1535610818304707
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inactivation of the Euchromatic Histone-Lysine N-Methyltransferase 2 Pathway in Pancreatic Epithelial Cells Antagonizes Cancer Initiation and Pancreatitis-Associated Promotion by Altering Growth and Immune Gene Expression Networks

1
1. scibot 14 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.3389/fcell.2021.681153
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8261250/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness

1
1. scibot 14 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.7554/eLife.64212
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8266391/
Jun 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Single-PanIN-seq unveils that ARID1A deficiency promotes pancreatic tumorigenesis by attenuating KRAS-induced senescence

1
1. scibot 18 Jun 2021
  
  in Public
  
  Jackson LabNo: 008179
  
  DOI: 10.7554/eLife.64204
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8203294/
www.sciencedirect.com www.sciencedirect.com

Protocol to establish a lung adenocarcinoma immunotherapy allograft mouse model with FACS and immunofluorescence-based analysis of tumor response

1
1. scibot 15 Jun 2021
  
  in Public
  
  JAX:008179
  
  DOI: 10.1016/j.xpro.2021.100595
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2666166721003026
www.sciencedirect.com www.sciencedirect.com

Protocol for single-cell ATAC sequencing using combinatorial indexing in mouse lung adenocarcinoma

1
1. scibot 05 Jun 2021
  
  in Public
  
  008179
  
  DOI: 10.1016/j.xpro.2021.100583
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2666166721002902
May 2021
cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org

Cell of Origin Influences Pancreatic Cancer Subtype

1
1. scibot 10 May 2021
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1158/2159-8290.CD-20-0633
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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cancerdiscovery.aacrjournals.org/content/11/3/660
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Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer

1
1. scibot 09 May 2021
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.stem.2020.07.003
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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sciencedirect.com/science/article/pii/S1934590920303416
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Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation

1
1. scibot 08 May 2021
  
  in Public
  
  JAX:008179
  
  DOI: 10.1016/j.molcel.2021.01.010
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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sciencedirect.com/science/article/pii/S1097276521000101
Apr 2021
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Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis

1
1. scibot 23 Apr 2021
  
  in Public
  
  Strain: 008179
  
  DOI: 10.1016/j.ccell.2021.02.016
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S1535610821001185
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EPHA2-dependent outcompetition of KRASG12D mutant cells by wild-type neighbors in the adult pancreas

1
1. scibot 23 Apr 2021
  
  in Public
  
  The Jackson Laboratory 008179
  
  DOI: 10.1016/j.cub.2021.03.094
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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sciencedirect.com/science/article/pii/S096098222100467X
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High-content, targeted RNA-seq screening in organoids for drug discovery in colorectal cancer

1
1. scibot 21 Apr 2021
  
  in Public
  
  008179
  
  DOI: 10.1016/j.celrep.2021.109026
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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sciencedirect.com/science/article/pii/S2211124721003405
www.cell.com www.cell.com

Emergence of a High-Plasticity Cell State during Lung Cancer Evolution

1
1. scibot 20 Apr 2021
  
  in Public
  
  008179
  
  DOI: 10.1016/j.ccell.2020.06.012
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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cell.com/cancer-cell/fulltext/S1535-6108(20)30316-0
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Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma

1
1. scibot 20 Apr 2021
  
  in Public
  
  stock 008179
  
  DOI: 10.1016/j.ccell.2020.06.006
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S153561082030310X
www.sciencedirect.com www.sciencedirect.com

SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy

1
1. scibot 17 Apr 2021
  
  in Public
  
  JAX 008179
  
  DOI: 10.1016/j.ccell.2020.04.014
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @Naa003
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1535610820302130
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PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis

1
1. scibot 12 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.molcel.2021.02.001
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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sciencedirect.com/science/article/pii/S1097276521000873
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Skeletal Muscle Subpopulation Rearrangements upon Rhabdomyosarcoma Development through Single-Cell Mass Cytometry

1
1. scibot 04 Mar 2021
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.3390/jcm10040823
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @evieth
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7922544/
Feb 2021
elifesciences.org elifesciences.org

Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth

1
1. scibot 25 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.7554/eLife.53618
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
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elifesciences.org/articles/53618
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Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas

1
1. scibot 24 Feb 2021
  
  in Public
  
  Stock# 008179
  
  DOI: 10.1016/j.celrep.2021.108772
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124721000851
Dec 2020
www.sciencedirect.com www.sciencedirect.com

Lgr5 Marks Adult Progenitor Cells Contributing to Skeletal Muscle Regeneration and Sarcoma Formation

1
1. scibot 24 Dec 2020
  
  in Public
  
  JAX:008179
  
  DOI: 10.1016/j.celrep.2020.108535
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRIDCUR:Validated RRID:IMSR_JAX:008179
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sciencedirect.com/science/article/pii/S2211124720315242
Sep 2020
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Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma

1
1. scibot 25 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.cell.2020.03.062
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867420303950
www.sciencedirect.com www.sciencedirect.com

Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer

1
1. scibot 09 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.cell.2020.03.008
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRIDCUR:Validated RRID:IMSR_JAX:008179
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sciencedirect.com/science/article/pii/S0092867420302701
www.sciencedirect.com www.sciencedirect.com

High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down

1
1. scibot 04 Sep 2020
  
  in Public
  
  JAX Stock No. 008179
  
  DOI: 10.1016/j.molcel.2020.05.009
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
  Curator comments: B6.129S4-Krastm4Tyj/J Mus musculus IMSR Cat# JAX:008179
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1097276520303105
www.nature.com www.nature.com

The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer

1
1. scibot 04 Sep 2020
  
  in Public
  
  JaxLab, Stock number 008179
  
  DOI: 10.1038/s41388-020-1196-5
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
  Curator comments: IMSR Cat# JAX:008179, B6.129S4-Krastm4Tyj/J Mus musculus
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Missing
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nature.com/articles/s41388-020-1196-5
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Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer

1
1. scibot 03 Sep 2020
  
  in Public
  
  The Jackson LaboratoryCat# 008179
  
  DOI: 10.1016/j.stem.2020.02.008
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1934590920300618
Jan 2020
www.sciencedirect.com www.sciencedirect.com

IL-33 Signaling Alters Regulatory T Cell Diversity in Support of Tumor Development

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.celrep.2019.10.120
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719314536
elifesciences.org elifesciences.org

Mutationally-activated PI3’-kinase-α promotes de-differentiation of lung tumors initiated by the BRAFV600E oncoprotein kinase

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.7554/eLife.43668
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Validated
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elifesciences.org/articles/43668
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p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.ccell.2019.01.006
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819300406
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Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  DOI: 10.1016/j.devcel.2018.11.001
  
  Resource: (IMSR Cat# JAX_008179,RRID:IMSR_JAX:008179)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1534580718309195
Nov 2018
www.sciencedirect.com www.sciencedirect.com

The Cdkn1aSUPER Mouse as a Tool to Study p53-Mediated Tumor Suppression

1
1. scibot 05 Nov 2018
  
  in Public
  
  JAX:008179
  
  Curator: @Jmenke
  
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  RRID:IMSR_JAX:008179
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124718315390
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The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  Curator: @Jmenke
  
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  RRID:IMSR_JAX:008179
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1074761318304357
cancerres.aacrjournals.org cancerres.aacrjournals.org

Long chain n-3 fatty acids attenuate oncogenic KRas-driven proliferation by altering plasma membrane nanoscale proteolipid composition

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  Curator: @evieth
  
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  RRID:IMSR_JAX:008179
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Validated
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cancerres.aacrjournals.org/content/78/14/3899
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PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism

1
1. scibot 05 Nov 2018
  
  in Public
  
  008179
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:008179
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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  RRID:IMSR_JAX:008179 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1534580718305975
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Hedgehog Pathway Drives Fusion-Negative Rhabdomyosarcoma Initiated From Non-myogenic Endothelial Progenitors

1
1. scibot 05 Nov 2018
  
  in Public
  
  JAX:008179
  
  Resource used:
  
  RRID:IMSR_JAX:008179
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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sciencedirect.com/science/article/pii/S153561081730524X
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Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:008179
  
  Resource used:
  
  RRID:IMSR_JAX:008179
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
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sciencedirect.com/science/article/pii/S0092867417312448
Nov 2017
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Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors

1
1. scibot 08 Nov 2017
  
  in Public
  
  JAX:008179
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:008179
  
  SciCrunch record: RRID:IMSR_JAX:008179
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:008179 RRIDCUR:Missing
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