144 Matching Annotations
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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aberrant methylation limits antitumoral inflammation in lung adenocarcinoma by restricting RIPK3 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13249207/
  3. Jun 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Diet-induced phospholipid remodeling dictates ferroptosis sensitivity and tumorigenesis in the pancreas
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  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of polarity by Cdc42 depletion and oncogenic Kras activation in the mouse intestinal epithelia leads to a necrotizing enterocolitis (NEC)-like disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC13223224/
  6. May 2026
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    Bcl-xL blockade targets neutrophils and synergizes with chemotherapy in lung squamous cell carcinoma
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    A conserved re-epithelialization program underlies malignancy in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S1535610826001753
  9. Apr 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Myofibroblasts induce neuroplasticity to promote pancreatic inflammation and cancer progression
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    An autochthonous CRISPR activation screening platform for characterizing tissue-specific oncogene selection
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    Corrigendum to “Histamine H1 receptor: a potential therapeutic target for pancreatic ductal adenocarcinoma”
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  14. Mar 2026
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    Targeting PI3Kδ suppresses pancreatic cancer by dual disruption of fibrosis and immune evasion
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  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RORγt Inhibition Reduces Pro-Tumor Inflammation and Decreases Tumor Growth in Experimental Models of Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12288671/
  17. Feb 2026
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Netrin-1 Promotes Pancreatic Tumorigenesis and Innervation through NEO1
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  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune Stromal Components Impede Biological Effectiveness of Carbon Ion Therapy in a Preclinical Model of Pancreatic Ductal Adenocarcinoma
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  20. Jan 2026
  21. www.science.org www.science.org
    Aberrant methylation limits antitumoral inflammation in lung adenocarcinoma by restricting RIPK3 expression
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    Intrinsic resistance to RAS inhibitors is driven by dysregulation of KRAS degradation
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    MITA/STING-driven CD38 induction in Siglec-Flow macrophages promotes regulatory T cell survival and non-small cell lung cancer progression
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  24. Dec 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SMURF2 facilitates GAP17 Isoform 1 membrane displacement to promote mutant p53-KRAS oncogenic synergy
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  26. Nov 2025
  27. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Protein kinase Cι dictates tumor trajectory, cell plasticity, and immune surveillance in lung adenocarcinoma
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    Functional mapping of epigenomic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes
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  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EML4-ALK variant-specific genetic interactions shape lung tumorigenesis
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  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aging represses oncogenic KRAS-driven lung tumorigenesis and alters tumor suppression
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    Injury and inflammation promote cancer progression at the anorectal junction
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    Senolytic-sensitive p16Ink4a+ fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity
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    Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
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  34. Oct 2025
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    Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas
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    Distinct T cell functions enable efficient immunoediting and prevent tumor emergence of developing sarcomas
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  37. Sep 2025
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of Sorting Nexin 10 accelerates KRAS-induced pancreatic tumorigenesis
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    A pathological role of O-GlcNAcylation-driven TR11B production and function in lung adenocarcinoma
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    Early adipose tissue wasting in a preclinical model of human lung cancer cachexia
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  41. Aug 2025
  42. www.biorxiv.org www.biorxiv.org
    L1CAM signaling through planar cell polarity generates SOX2+ metastatic progenitors in lung adenocarcinoma
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    biorxiv.org/content/10.1101/2025.08.22.671773v1
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A RAS(ON) Multi-Selective Inhibitor Combination Therapy Triggers Long-term Tumor Control through Senescence-Associated Tumor-Immune Equilibrium in Pancreatic Ductal Adenocarcinoma
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  44. Jul 2025
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Early adipose tissue wasting in a novel preclinical model of human lung cancer cachexia
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  46. Jun 2025
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    Protocol for adeno-associated virus-mediated gene delivery to accelerate pancreatic carcinogenesis in mice
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  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FGFR2 Abrogation Intercepts Pancreatic Ductal Adenocarcinoma Development
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  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A STAG2-PAXIP1/PAGR1 axis suppresses lung tumorigenesis
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  50. May 2025
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    Regulatory network analysis of Dclk1 gene expression reveals a tuft cell-ILC2 axis that inhibits pancreatic tumor progression
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    Distinct Roles for the Thioredoxin and Glutathione Antioxidant Systems in Nrf2-Mediated Lung Tumor Initiation and Progression
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  53. Apr 2025
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    Histamine 1 Receptor (HRH1): A potential therapeutic target for Pancreatic Ductal Adenocarcinoma
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  56. Mar 2025
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  58. Feb 2025
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combinatorial In Vivo Genome Editing Identifies Widespread Epistasis and an Accessible Fitness Landscape During Lung Tumorigenesis
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    KRAS4B oncogenic mutants promote non-small cell lung cancer progression via the interaction of deubiquitinase USP25 with RNF31
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  61. aacrjournals.org aacrjournals.org
    Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis
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    Disrupting AGR2/IGF1 paracrine and reciprocal signaling for pancreatic cancer therapy
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  63. Dec 2024
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Imaging NRF2 activation in non-small cell lung cancer with positron emission tomography
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  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors
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  66. Nov 2024
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FAK loss reduces BRAFV600E-induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation
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    A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression
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  69. Sep 2024
  70. www.biorxiv.org www.biorxiv.org
    A STAG2-PAXIP1/PAGR1 axis suppresses lung tumorigenesis
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  71. Aug 2024
  72. www.biorxiv.org www.biorxiv.org
    Functional mapping of epigenetic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes
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    FRA1 controls acinar cell plasticity during murine KrasG12D-induced pancreatic acinar to ductal metaplasia
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  75. Jul 2024
  76. www.science.org www.science.org
    Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer
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    Cancer-associated endocrine cells participate in pancreatic carcinogenesis
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  78. Jun 2024
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    Aging represses lung tumorigenesis and alters tumor suppression
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  80. May 2024
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    CRACD loss induces neuroendocrine cell plasticity of lung adenocarcinoma
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    Expression of the membrane tetraspanin claudin 18 on cancer cells promotes T lymphocyte infiltration and antitumor immunity in pancreatic cancer
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  83. Apr 2024
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    The UBE2F-CRL5ASB11-DIRAS2 axis is an oncogene and tumor suppressor cascade in pancreatic cancer cells
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  85. Mar 2024
  86. www.biorxiv.org www.biorxiv.org
    Modeling the genomic complexity of human cancer using Cas12a mice
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    Combinatorial in vivo genome editing identifies widespread epistasis during lung tumorigenesis
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  88. Feb 2024
  89. aacrjournals.org aacrjournals.org
    Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma
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    Exosomes define a local and systemic communication network in healthy pancreas and pancreatic ductal adenocarcinoma
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  91. Jan 2024
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state
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    Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
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  94. Dec 2023
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    A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas
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  97. Oct 2023
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    Novel tumor organoid-based mouse model to study image-guided radiation therapy of rectal cancer after non-invasive and precise endoscopic implantation
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    Decreased liver B vitamin-related enzymes as a metabolic hallmark of cancer cachexia
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  100. Aug 2023
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development
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  103. Jun 2023
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression
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    Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion
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  106. www.cell.com www.cell.com
    Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer
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  107. May 2023
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gender-specific changes of the gut microbiome correlate with tumor development in murine models of pancreatic cancer
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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors
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  110. Mar 2023
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    Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth
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  112. Dec 2022
  113. www.sciencedirect.com www.sciencedirect.com
    The Sag-Shoc2 axis regulates conversion of mPanINs to cystic lesions in Kras pancreatic tumor model
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    sciencedirect.com/science/article/pii/S2211124722017296
  114. Nov 2022
  115. aacrjournals.org aacrjournals.org
    The cAMP/PKA/CREB and TGF-β/SMAD4 pathways regulate stemness and metastatic potential in colorectal cancer cells
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    aacrjournals.org/cancerres/article/82/22/4179/710134/The-cAMP-PKA-CREB-and-TGF-SMAD4-Pathways-Regulate
  116. Oct 2022
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    The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes
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  119. Sep 2022
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9271144/
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
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  122. Aug 2022
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    Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma
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  129. Mar 2022
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  131. Feb 2022
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  133. Jan 2022
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  136. Dec 2021
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  138. Nov 2021
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  141. Oct 2021
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  143. Sep 2021
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  150. Jul 2021
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  158. Jun 2021
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  162. May 2021
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  174. Mar 2021
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  176. Feb 2021
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  187. Jan 2020
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  192. Nov 2018
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