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25 Matching Annotations

Aug 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting CCR1 remodels the tumor microenvironment and relieves immune suppression in pancreatic cancer

1
1. scibot 05 Aug 2026
  
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  RRID:IMSR_JAX:008652
  
  DOI: 10.1158/2326-6066.CIR-25-1300
  
  Resource: RRID:IMSR_JAX:008652
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13429029/
Jun 2026
www.nature.com www.nature.com

ULK1 knockout suppresses pancreatic cancer progression by inhibiting autophagy and enhancing antitumor immunity

1
1. scibot 13 Jun 2026
  
  in Public
  
  strain no. 008652
  
  DOI: 10.1038/s12276-025-01590-2
  
  Resource: RRID:IMSR_JAX:008652
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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nature.com/articles/s12276-025-01590-2
Mar 2026
www.sciencedirect.com www.sciencedirect.com

Myofibroblast programming blocks differentiation of TLS-organizing fibroblastic reticular cells in pancreatic cancer

1
1. scibot 27 Mar 2026
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1016/j.ccell.2026.03.004
  
  Resource: RRID:IMSR_JAX:008652
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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scibot

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sciencedirect.com/science/article/pii/S153561082600156X
Oct 2025
www.sciencedirect.com www.sciencedirect.com

Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas

1
1. scibot 30 Oct 2025
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1016/j.celrep.2025.116487
  
  Resource: RRID:IMSR_JAX:008652
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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scibot

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sciencedirect.com/science/article/pii/S2211124725012586
Sep 2025
www.sciencedirect.com www.sciencedirect.com

A pathological role of O-GlcNAcylation-driven TR11B production and function in lung adenocarcinoma

1
1. scibot 11 Sep 2025
  
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  RRID:IMSR_JAX:008652
  
  DOI: 10.1016/j.devcel.2025.08.010
  
  Resource: RRID:IMSR_JAX:008652
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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sciencedirect.com/science/article/pii/S1534580725005301
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FGFR2 Abrogation Intercepts Pancreatic Ductal Adenocarcinoma Development

1
1. scibot 18 Jun 2025
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1158/0008-5472.CAN-24-4576
  
  Resource: RRID:IMSR_JAX:008652
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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RRID:IMSR_JAX:008652

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pmc.ncbi.nlm.nih.gov/articles/PMC12169444/
Apr 2025
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 04 Apr 2025
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1158/0008-5472.can-24-4576
  
  Resource: RRID:IMSR_JAX:008652
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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scibot

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52.53.155.43/d82b50f0340a265ea39586fdf6016ce1aa48cfa1/PDF-html.html
Aug 2024
www.sciencedirect.com www.sciencedirect.com

Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines

1
1. scibot 21 Aug 2024
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1016/j.celrep.2024.114616
  
  Resource: RRID:IMSR_JAX:008652
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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sciencedirect.com/science/article/pii/S2211124724009665
May 2024
www.sciencedirect.com www.sciencedirect.com

Expression of the membrane tetraspanin claudin 18 on cancer cells promotes T lymphocyte infiltration and antitumor immunity in pancreatic cancer

1
1. scibot 16 May 2024
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1016/j.immuni.2024.04.021
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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RRID:IMSR_JAX:008652

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sciencedirect.com/science/article/pii/S1074761324002267
Feb 2024
aacrjournals.org aacrjournals.org

Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma

1
1. scibot 23 Feb 2024
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1158/1078-0432.CCR-23-1143
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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RRID:IMSR_JAX:008652

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scibot

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aacrjournals.org/clincancerres/article/29/24/5183/731660/Nuclear-GRP78-Promotes-Metabolic-Reprogramming-and
link.springer.com link.springer.com

Exosomes define a local and systemic communication network in healthy pancreas and pancreatic ductal adenocarcinoma

1
1. scibot 22 Feb 2024
  
  in Public
  
  JAX:008652
  
  DOI: 10.1038/s41467-024-45753-7
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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RRID:IMSR_JAX:008652

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link.springer.com/article/10.1038/s41467-024-45753-7
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state

1
1. scibot 30 Jan 2024
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1038/s41419-024-06460-9
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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RRID:IMSR_JAX:008652

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10810848/
www.sciencedirect.com www.sciencedirect.com

Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

2
1. scibot 04 Jan 2024
  
  in Public
  
  JAX:008652
  
  DOI: 10.1016/j.devcel.2023.07.025
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
  What is this?
  
  RRID:IMSR_JAX:008652
2. scibot 04 Jan 2024
  
  in Public
  
  JAX:008652
  
  DOI: 10.1016/j.devcel.2023.07.025
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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RRID:IMSR_JAX:008652

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scibot

URL

sciencedirect.com/science/article/pii/S1534580723003945
Dec 2023
52.53.155.43 52.53.155.43

ccr-23-1143-html.html

1
1. scibot 01 Dec 2023
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1158/1078-0432.ccr-23-1143
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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RRID:IMSR_JAX:008652

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scibot

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52.53.155.43/aa509a782208f9df8c6754b69c5c07021388a9c4/ccr-23-1143-html.html
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression

1
1. scibot 31 Aug 2023
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1186/s12967-023-04448-1
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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RRID:IMSR_JAX:008652

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10463307/
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Gender-specific changes of the gut microbiome correlate with tumor development in murine models of pancreatic cancer

1
1. scibot 31 May 2023
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1016/j.isci.2023.106841
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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RRID:IMSR_JAX:008652

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10225934/
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression

1
1. scibot 22 Sep 2022
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1136/gutjnl-2021-324994
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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RRID:IMSR_JAX:008652

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9271144/
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis

1
1. scibot 25 Jun 2022
  
  in Public
  
  JAX:008652
  
  DOI: 10.1016/j.molcel.2022.06.005
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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RRID:IMSR_JAX:008652

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scibot

URL

sciencedirect.com/science/article/pii/S109727652200541X
Mar 2022
www.sciencedirect.com www.sciencedirect.com

Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin

1
1. scibot 02 Mar 2022
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1016/j.celrep.2022.110441
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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RRID:IMSR_JAX:008652

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722001681
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer

1
1. scibot 04 Feb 2022
  
  in Public
  
  JAX:008652
  
  DOI: 10.1016/j.ccell.2022.01.003
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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RRID:IMSR_JAX:008652

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scibot

URL

sciencedirect.com/science/article/pii/S1535610822000058
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy

1
1. scibot 16 Aug 2021
  
  in Public
  
  JAX:008652
  
  DOI: 10.1016/j.cell.2021.07.020
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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RRID:IMSR_JAX:008652

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scibot

URL

sciencedirect.com/science/article/pii/S0092867421008795
May 2021
cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org

Cell of Origin Influences Pancreatic Cancer Subtype

1
1. scibot 10 May 2021
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1158/2159-8290.CD-20-0633
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652
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RRID:IMSR_JAX:008652

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scibot

URL

cancerdiscovery.aacrjournals.org/content/11/3/660
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1016/j.cell.2020.03.062
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRIDCUR:Validated RRID:IMSR_JAX:008652
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RRIDCUR:Validated

RRID:IMSR_JAX:008652

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scibot

URL

sciencedirect.com/science/article/pii/S0092867420303950
Jan 2020
www.sciencedirect.com www.sciencedirect.com

p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:008652
  
  DOI: 10.1016/j.ccell.2019.01.006
  
  Resource: (IMSR Cat# JAX_008652,RRID:IMSR_JAX:008652)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:008652
  
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  RRID:IMSR_JAX:008652 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:008652

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819300406