Hypothesis

19 Matching Annotations

Oct 2025
www.sciencedirect.com www.sciencedirect.com

Uncovering the individual immunotherapeutic roles of PTPN1 and PTPN2 in T cells during dual inhibition

1
1. scibot 15 Oct 2025
  
  in Public
  
  The Jackson laboratoryCat# 008766
  
  DOI: 10.1016/j.isci.2025.113610
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
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  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

sciencedirect.com/science/article/pii/S2589004225018711
www.sciencedirect.com www.sciencedirect.com

The transcriptional repressor BLIMP1 enforces TCF-1-dependent and -independent restriction of the memory fate of CD8+ T cells

1
1. scibot 08 Oct 2025
  
  in Public
  
  RRID:IMSR_JAX:008766
  
  DOI: 10.1016/j.immuni.2025.09.008
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
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  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

sciencedirect.com/science/article/pii/S1074761325004194
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4

1
1. scibot 27 Sep 2025
  
  in Public
  
  RRID:IMSR_JAX:008766
  
  DOI: 10.1016/j.immuni.2025.09.003
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
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  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

sciencedirect.com/science/article/pii/S1074761325004145
www.sciencedirect.com www.sciencedirect.com

Immunometabolic defects of CD8+ T cells disrupt gut barrier integrity in people with HIV

1
1. scibot 12 Sep 2025
  
  in Public
  
  Jackson LabsStock# 008766
  
  DOI: 10.1016/j.cell.2025.08.024
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
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  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

sciencedirect.com/science/article/pii/S0092867425009791
Aug 2025
www.sciencedirect.com www.sciencedirect.com

Long-range deployment of tumor-antigen-specific cytotoxic T lymphocytes inhibits lung metastasis of breast cancer

1
1. scibot 28 Aug 2025
  
  in Public
  
  JAX:008766
  
  DOI: 10.1016/j.devcel.2025.08.003
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
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  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

sciencedirect.com/science/article/pii/S1534580725005039
www.nature.com www.nature.com

SATB1 is a key regulator of quiescence in stem-like CD8+ T cells

1
1. scibot 27 Aug 2025
  
  in Public
  
  stock no. 008766
  
  DOI: 10.1038/s41590-025-02257-w
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
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  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

nature.com/articles/s41590-025-02257-w
Jul 2025
www.biorxiv.org www.biorxiv.org

Pik3ip1/TrIP Regulation of PI3K Restricts CD8 T Cell Anti-Tumor Immunity

1
1. scibot 22 Jul 2025
  
  in Public
  
  Strain #008766
  
  DOI: 10.1101/2025.07.10.664200
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
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  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

biorxiv.org/content/10.1101/2025.07.10.664200v1
www.cell.com www.cell.com

Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy

2
1. scibot 15 Jul 2025
  
  in Public
  
  Stock No: 008766
  
  DOI: 10.1016/j.cell.2025.06.018
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
  What is this?
  
  RRID:IMSR_JAX:008766
2. scibot 15 Jul 2025
  
  in Public
  
  Stock No: 008766
  
  DOI: 10.1016/j.cell.2025.06.018
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
  What is this?
  
  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

cell.com/cell/fulltext/S0092-8674(25)00684-1
Mar 2025
link.springer.com link.springer.com

Immunotherapy with low-dose IL-2 attenuates vascular injury in mice with diabetic and neovascular retinopathy by restoring the balance between Foxp3+ Tregs and CD8+ T cells

1
1. scibot 29 Mar 2025
  
  in Public
  
  RRID:IMSR_JAX:008766
  
  DOI: 10.1007/s00125-025-06412-8
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
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  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

link.springer.com/article/10.1007/s00125-025-06412-8
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Protocol to quantify the activation dynamics of tumor-associated T cells in mice by functional intravital microscopy

1
1. scibot 26 Sep 2024
  
  in Public
  
  RRID:IMSR_JAX:008766
  
  DOI: 10.1016/j.xpro.2024.103310
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
  What is this?
  
  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

sciencedirect.com/science/article/pii/S2666166724004751
May 2024
www.biorxiv.org www.biorxiv.org

The Gut Microbiome Controls Liver Tumors via the Vagus Nerve

1
1. scibot 09 May 2024
  
  in Public
  
  008766
  
  DOI: 10.1101/2024.01.23.576951
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
  What is this?
  
  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

biorxiv.org/content/10.1101/2024.01.23.576951v1
Nov 2023
www.nature.com www.nature.com

Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity

1
1. scibot 25 Nov 2023
  
  in Public
  
  RRID:IMSR_JAX:008766
  
  DOI: 10.1038/s41586-023-06749-3
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
  What is this?
  
  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

nature.com/articles/s41586-023-06749-3
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Intertumoral Differences Dictate the Outcome of TGF-β Blockade on the Efficacy of Viro-Immunotherapy

1
1. scibot 04 Mar 2023
  
  in Public
  
  RRID:IMSR_JAX:008766
  
  DOI: 10.1158/2767-9764.CRC-23-0019
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
  What is this?
  
  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9973387/
Jan 2023
www.sciencedirect.com www.sciencedirect.com

CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy

1
1. scibot 04 Jan 2023
  
  in Public
  
  JAX:008766
  
  DOI: 10.1016/j.xcrm.2022.100878
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
  What is this?
  
  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

sciencedirect.com/science/article/pii/S2666379122004426
Nov 2022
www.sciencedirect.com www.sciencedirect.com

The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity

1
1. scibot 16 Nov 2022
  
  in Public
  
  008766
  
  DOI: 10.1016/j.immuni.2022.10.020
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
  What is this?
  
  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

sciencedirect.com/science/article/pii/S1074761322005611
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Neuropilin-1 cooperates with PD-1 in CD8+ T-cells predicting outcomes in melanoma patients treated with anti-PD1

1
1. scibot 17 Jun 2022
  
  in Public
  
  RRID:IMSR_JAX:008766
  
  DOI: 10.1016/j.isci.2022.104353
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
  What is this?
  
  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

sciencedirect.com/science/article/pii/S2589004222006241
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis

1
1. scibot 03 Jun 2022
  
  in Public
  
  Jackson LaboratoryStock no.: 008766
  
  DOI: 10.1016/j.chom.2022.05.006
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
  What is this?
  
  RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9841318/
May 2021
www.sciencedirect.com www.sciencedirect.com

T Cell Receptor Is Required for Differentiation, but Not Maintenance, of Intestinal CD4+ Intraepithelial Lymphocytes

1
1. scibot 15 May 2021
  
  in Public
  
  Jax 008766
  
  DOI: 10.1016/j.immuni.2020.09.003
  
  Resource: (IMSR Cat# JAX_008766,RRID:IMSR_JAX:008766)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008766
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:008766
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RRID:IMSR_JAX:008766

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761320303976