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Inhibiting KRAS with CD47 and immune checkpoint overcomes intrinsic resistance to combined KRAS and immune checkpoint inhibitor therapy

1
1. scibot 30 Aug 2025
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.xcrm.2025.102317
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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sciencedirect.com/science/article/pii/S2666379125003908
Jul 2025
www.biorxiv.org www.biorxiv.org

Multilayered molecular and cellular mechanisms underlying intestinal epithelial regeneration

1
1. scibot 25 Jul 2025
  
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  #JAX008875
  
  DOI: 10.1101/2025.07.20.665802
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @dhovakimyan1
  
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biorxiv.org/content/10.1101/2025.07.20.665802v1
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Telocytes deliver essential Wnts directly to murine intestinal stem cells via synapse-like contacts

1
1. scibot 24 Jul 2025
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.devcel.2025.06.040
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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sciencedirect.com/science/article/pii/S1534580725004381
May 2025
52.53.155.43 52.53.155.43

CapdevilaCastillo_columbia_0054D_18600-html.html

1
1. scibot 22 May 2025
  
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  JAX:008875
  
  DOI: 10.7916/kcm5-sk40
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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52.53.155.43/defa13d4e31bf105e951133a04f91af42d68a175/CapdevilaCastillo_columbia_0054D_18600-html.html
Apr 2025
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Dual states of murine Bmi1-expressing intestinal stem cells drive epithelial development utilizing non-canonical Wnt signaling

1
1. scibot 24 Apr 2025
  
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  Jackson Laboratory008875
  
  DOI: 10.1016/j.devcel.2025.03.014
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S1534580725001777
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Intestinal secretory differentiation reflects niche-driven phenotypic and epigenetic plasticity of a common signal-responsive terminal cell

1
1. scibot 09 Apr 2025
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.stem.2025.03.005
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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sciencedirect.com/science/article/pii/S1934590925000955
Mar 2025
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Vagal pathway activation links chronic stress to decline in intestinal stem cell function

1
1. scibot 24 Mar 2025
  
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  The Jackson Laboratory Stock_008875
  
  DOI: 10.1016/j.stem.2025.02.016
  
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  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Unresolved
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sciencedirect.com/science/article/pii/S1934590925000840
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Rediscovering the rete ovarii, a secreting auxiliary structure to the ovary

1
1. scibot 21 Mar 2025
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.7554/eLife.96662
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11922502/
52.53.155.43 52.53.155.43

1-s2.0-S0016508525004652-main-html.html

1
1. scibot 13 Mar 2025
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1053/j.gastro.2025.01.252
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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52.53.155.43/102b713a896a92ff6c775133f76054d0b6648b53/1-s2.0-S0016508525004652-main-html.html
Feb 2025
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The balance between IFN-γ and ERK/MAPK signaling activities ensures lifelong maintenance of intestinal stem cells

1
1. scibot 14 Feb 2025
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.celrep.2025.115286
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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sciencedirect.com/science/article/pii/S2211124725000579
Jan 2025
52.53.155.43 52.53.155.43

A niche-dependent redox rheostat regulates epithelial stem cell fate in the distal colon

1
1. scibot 31 Jan 2025
  
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  Stock# 008875
  
  DOI: 10.1101/2025.01.26.634856
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @sjvitug
  
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52.53.155.43/79f18ee8720d66564852d009166058cb2d19618c/PDF-html.html
www.nature.com www.nature.com

Acoustic-pressure-driven ultrasonic activation of the mechanosensitive receptor RET and of cell proliferation in colonic tissue

1
1. scibot 04 Jan 2025
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1038/s41551-024-01300-9
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @scibot
  
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nature.com/articles/s41551-024-01300-9
Dec 2024
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Maternal gut microbiota influence stem cell function in offspring

1
1. scibot 24 Dec 2024
  
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  Jackson labCat# 008875
  
  DOI: 10.1016/j.stem.2024.10.003
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S1934590924003655
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Radical and lunatic fringes modulate notch ligands to support mammalian intestinal homeostasis

1
1. scibot 17 Dec 2024
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.7554/eLife.35710
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5896954/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mesenchymal GDNF promotes intestinal enterochromaffin cell differentiation

1
1. scibot 11 Dec 2024
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.isci.2024.111246
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11616604/
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Conditional Gene Expression in the Mouse Inner Ear Using Cre-loxP

1
1. scibot 22 Nov 2024
  
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  8875
  
  DOI: 10.1007/s10162-012-0324-5
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @AleksanderDrozdz
  
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  RRID:IMSR_JAX:008875
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pmc.ncbi.nlm.nih.gov/articles/PMC3346893/
Aug 2024
www.cell.com www.cell.com

Calorie Restriction Governs Intestinal Epithelial Regeneration through Cell-Autonomous Regulation of mTORC1 in Reserve Stem Cells

1
1. scibot 02 Aug 2024
  
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  Lgr5-eGFP-IRES-CreERT2(Jax mice strain 008875
  
  DOI: 10.1016/s2352-0779(18)30052-9
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
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  RRID:IMSR_JAX:008875
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cell.com/stem-cell-reports/pdfExtended/S2213-6711(18)30052-3
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cbl and Cbl-b ubiquitin ligases are essential for intestinal epithelial stem cell maintenance

1
1. scibot 18 Jul 2024
  
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  Jackson LaboratoryStock No: 008875
  
  DOI: 10.1016/j.isci.2024.109912
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
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  RRID:IMSR_JAX:008875
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ncbi.nlm.nih.gov/pmc/articles/PMC11225835/
Jun 2024
www.sciencedirect.com www.sciencedirect.com

Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells

1
1. scibot 07 Jun 2024
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.cell.2024.05.001
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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  RRID:IMSR_JAX:008875
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sciencedirect.com/science/article/pii/S0092867424004914
www.mdpi.com www.mdpi.com

Single-Cell Profiling Reveals the Impact of Genetic Alterations on the Differentiation of Inflammation-Induced Murine Colon Tumors

1
1. scibot 06 Jun 2024
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.3390/cancers16112040
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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mdpi.com/2072-6694/16/11/2040
May 2024
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Epithelial aPKC deficiency leads to stem cell loss preceding metaplasia in colorectal cancer initiation

1
1. scibot 30 May 2024
  
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  008875
  
  DOI: 10.1016/j.devcel.2024.05.001
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @abever99
  
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  DOI:10.1016/j.devcel.2024.05.001 RRID:IMSR_JAX:008875
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sciencedirect.com/science/article/pii/S1534580724002995
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Enterococcus-derived tyramine hijacks α2A-adrenergic receptor in intestinal stem cells to exacerbate colitis

1
1. scibot 24 May 2024
  
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  008875
  
  DOI: 10.1016/j.chom.2024.04.020
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @abever99
  
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  RRID:IMSR_JAX:008875
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sciencedirect.com/science/article/pii/S1931312824001409
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IL-22 promotes mucin-type O-glycosylation and MATH1+ cell-mediated amelioration of intestinal inflammation

1
1. scibot 14 May 2024
  
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  008875
  
  DOI: 10.1016/j.celrep.2024.114206
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @abever99
  
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  RRID:IMSR_JAX:008875
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sciencedirect.com/science/article/pii/S2211124724005345
52.53.155.43 52.53.155.43

Rediscovering the Rete Ovarii: a secreting auxiliary structure to the ovary

1
1. scibot 02 May 2024
  
  in Public
  
  JAX:008875
  
  DOI: 10.1101/2023.11.08.566085
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
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  RRID:IMSR_JAX:008875
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52.53.155.43/d464a1c8cbadac762260d7e95892d01d1077dc1a/2023.11.08.566085v2.full-html.html
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Telomere dysfunction alters intestinal stem cell dynamics to promote cancer

1
1. scibot 04 Apr 2024
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.devcel.2024.03.020
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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sciencedirect.com/science/article/pii/S1534580724001886
Feb 2024
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Scleroglucan protects the intestine from irradiation-induced injury by targeting the IL-17 signaling pathway

1
1. scibot 13 Feb 2024
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.intimp.2024.111614
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1567576924001322
www.biorxiv.org www.biorxiv.org

Single-cell profiling reveals the impact of genetic alterations on the differentiation of inflammation-induced colon tumors

1
1. scibot 09 Feb 2024
  
  in Public
  
  RRID:IMSR_JAX:008875
  
  DOI: 10.1101/2023.11.30.569463
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @scibot
  
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biorxiv.org/content/10.1101/2023.11.30.569463v1
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Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity

1
1. scibot 07 Feb 2024
  
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  Jax: 008875
  
  DOI: 10.1016/j.immuni.2024.01.002
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
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sciencedirect.com/science/article/pii/S107476132400027X
www.sciencedirect.com www.sciencedirect.com

Gut-liver axis calibrates intestinal stem cell fitness

1
1. scibot 03 Feb 2024
  
  in Public
  
  The Jackson LaboratoryCat# 008875
  
  DOI: 10.1016/j.cell.2024.01.001
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S0092867424000035
Jan 2024
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Mouse oocytes develop in cysts with the help of nurse cells

1
1. scibot 04 Jan 2024
  
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  008875
  
  DOI: 10.1016/j.cell.2022.05.001
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @bandrow
  
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  RRID:IMSR_JAX:008875
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sciencedirect.com/science/article/pii/S0092867422005797
Dec 2023
www.cell.com www.cell.com

Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice

1
1. scibot 19 Dec 2023
  
  in Public
  
  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.devcel.2023.11.013
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @scibot
  
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cell.com/developmental-cell/fulltext/S1534-5807(23)00611-1
Nov 2023
www.sciencedirect.com www.sciencedirect.com

p57Kip2 acts as a transcriptional corepressor to regulate intestinal stem cell fate and proliferation

1
1. scibot 10 Nov 2023
  
  in Public
  
  JAX:008875
  
  DOI: 10.1016/j.celrep.2023.112659
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
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  RRID:IMSR_JAX:008875
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sciencedirect.com/science/article/pii/S2211124723006708
Aug 2023
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Wound-healing plasticity enables clonal expansion of founder progenitor cells in colitis

1
1. scibot 31 Aug 2023
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.devcel.2023.08.011
  
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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

β-Catenin Drives Butyrophilin-like Molecule Loss and γδ T-cell Exclusion in Colon Cancer

1
1. scibot 05 Aug 2023
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1158/2326-6066.CIR-22-0644
  
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Jan 2023
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A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling

1
1. scibot 19 Jan 2023
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.stem.2022.12.008
  
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Dec 2022
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Gut microbiota promotes stem cell differentiation through macrophage and mesenchymal niches in early postnatal development

1
1. scibot 06 Dec 2022
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.immuni.2022.11.003
  
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Nov 2022
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The cAMP/PKA/CREB and TGF-β/SMAD4 pathways regulate stemness and metastatic potential in colorectal cancer cells

1
1. scibot 22 Nov 2022
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1158/0008-5472.CAN-22-1369
  
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aacrjournals.org/cancerres/article/82/22/4179/710134/The-cAMP-PKA-CREB-and-TGF-SMAD4-Pathways-Regulate
elifesciences.org elifesciences.org

Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii

2
1. scibot 02 Nov 2022
  
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  Jackson LaboratoryStock #:008875
  
  DOI: 10.7554/eLife.81088
  
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2. scibot 02 Nov 2022
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.7554/eLife.81088
  
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Oct 2022
52.53.155.43 52.53.155.43

can-22-1369-html.html

1
1. scibot 27 Oct 2022
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1158/0008-5472.can-22-1369
  
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52.53.155.43/73ac479c11a5b7254565d9c8982a4bd5bdf3415d/can-22-1369-html.html
www.nature.com www.nature.com

Zymosan-A promotes the regeneration of intestinal stem cells by upregulating ASCL2

1
1. scibot 22 Oct 2022
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1038/s41419-022-05301-x
  
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nature.com/articles/s41419-022-05301-x
Sep 2022
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Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis

1
1. scibot 08 Sep 2022
  
  in Public
  
  B6.129P2-Lgr5tm1(cre/ERT2)Cle/J
  
  DOI: 10.1016/j.celrep.2022.111313
  
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Aug 2022
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Lymphangiocrine signals are required for proper intestinal repair after cytotoxic injury

1
1. scibot 06 Aug 2022
  
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  JAX:008875
  
  DOI: 10.1016/j.stem.2022.07.007
  
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Jul 2022
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PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis

1
1. scibot 27 Jul 2022
  
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  JAX# 008875
  
  DOI: 10.1016/j.celrep.2022.111125
  
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Mesenchymal-epithelial interaction regulates gastrointestinal tract development in mouse embryos

1
1. scibot 13 Jul 2022
  
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  The Jackson LaboratoryCat#008875
  
  DOI: 10.1016/j.celrep.2022.111053
  
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sciencedirect.com/science/article/pii/S2211124722008476
Jun 2022
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Lymphatics act as a signaling hub to regulate intestinal stem cell activity

1
1. scibot 22 Jun 2022
  
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  The Jackson Laboratory008875
  
  DOI: 10.1016/j.stem.2022.05.007
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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sciencedirect.com/science/article/pii/S1934590922002077
May 2022
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PDGFRα-induced stromal maturation is required to restrain postnatal intestinal epithelial stemness and promote defense mechanisms

1
1. scibot 06 May 2022
  
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  JAX stock #008875
  
  DOI: 10.1016/j.stem.2022.04.005
  
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sciencedirect.com/science/article/pii/S1934590922001588
Mar 2022
www.nature.com www.nature.com

Ret kinase-mediated mechanical induction of colon stem cells by tumor growth pressure stimulates cancer progression in vivo

1
1. scibot 05 Mar 2022
  
  in Public
  
  RRID:IMSR_JAX:00887548
  
  DOI: 10.1038/s42003-022-03079-4
  
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nature.com/articles/s42003-022-03079-4
Feb 2022
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Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity

2
1. scibot 11 Feb 2022
  
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  008875
  
  DOI: 10.1016/j.devcel.2022.01.006
  
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2. scibot 09 Feb 2022
  
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  008875
  
  DOI: 10.1016/j.devcel.2022.01.006
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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Jan 2022
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IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment

1
1. scibot 27 Jan 2022
  
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  Cat#: 008875
  
  DOI: 10.1016/j.immuni.2021.12.016
  
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Adaptive differentiation promotes intestinal villus recovery

1
1. scibot 11 Jan 2022
  
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  Cat# 008875
  
  DOI: 10.1016/j.devcel.2021.12.012
  
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sciencedirect.com/science/article/abs/pii/S1534580721010327
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Bacterial-driven inflammation and mutant BRAF expression combine to promote murine colon tumorigenesis that is sensitive to immune checkpoint therapy

1
1. scibot 03 Jan 2022
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1158/2159-8290.CD-20-0770
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8295175/
Nov 2021
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Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine

1
1. scibot 24 Nov 2021
  
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  JAX:008875
  
  DOI: 10.1016/j.celrep.2021.110044
  
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sciencedirect.com/science/article/pii/S2211124721015308
Sep 2021
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SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling

1
1. scibot 28 Sep 2021
  
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  Stock No: 008875
  
  DOI: 10.1016/j.stem.2021.09.004
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1934590921003805
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Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis

1
1. scibot 17 Sep 2021
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.stem.2021.08.007
  
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sciencedirect.com/science/article/pii/S1934590921003441
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Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche

1
1. scibot 08 Sep 2021
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.celrep.2021.109674
  
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sciencedirect.com/science/article/pii/S2211124721011189
Aug 2021
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Engineered Glycocalyx Regulates Stem Cell Proliferation in Murine Crypt Organoids

1
1. scibot 09 Aug 2021
  
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  JAX:008875
  
  DOI: 10.1016/j.chembiol.2018.01.010
  
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sciencedirect.com/science/article/pii/S2451945618300321
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PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis

1
1. scibot 08 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.devcel.2018.02.010
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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sciencedirect.com/science/article/pii/S1534580718301059
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 04 Aug 2021
  
  in Public
  
  JAX:008875
  
  DOI: 10.1016/j.cels.2016.08.010
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5052454/
Jul 2021
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T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation

1
1. scibot 30 Jul 2021
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.cell.2018.10.008
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @Jmenke
  
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  RRIDCUR:Validated RRID:IMSR_JAX:008875
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sciencedirect.com/science/article/pii/S0092867418313163
www.sciencedirect.com www.sciencedirect.com

Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells

1
1. scibot 29 Jul 2021
  
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  The Jackson LaboratoryCat# 008875
  
  DOI: 10.1016/j.cell.2019.10.015
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @ethanbadger
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Unrecognized
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sciencedirect.com/science/article/pii/S0092867419311651
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Untitled document

1
1. scibot 29 Jul 2021
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.celrep.2018.09.059
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
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sciencedirect.com/science/article/pii/S2211124718315043
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation

1
1. scibot 27 Jul 2021
  
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  008875
  
  DOI: 10.1172/JCI87588
  
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  Curator: @mpairish
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5272174/
Jun 2021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity

1
1. scibot 09 Jun 2021
  
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  Stock No: 008875
  
  DOI: 10.1016/j.celrep.2021.109212
  
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  RRIDCUR:Missing RRID:IMSR_JAX:008875
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pmc.ncbi.nlm.nih.gov/articles/PMC8258630/
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Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization

1
1. scibot 08 Jun 2021
  
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  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.stem.2021.05.007
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:008875
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sciencedirect.com/science/article/pii/S1934590921002253
www.sciencedirect.com www.sciencedirect.com

Nkx2-2 expressing taste cells in endoderm-derived taste papillae are committed to the type III lineage

1
1. scibot 08 Jun 2021
  
  in Public
  
  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.ydbio.2021.05.020
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S001216062100141X
May 2021
www.sciencedirect.com www.sciencedirect.com

Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer

1
1. scibot 09 May 2021
  
  in Public
  
  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.stem.2020.07.003
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:008875
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sciencedirect.com/science/article/pii/S1934590920303416
www.sciencedirect.com www.sciencedirect.com

Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.immuni.2020.10.014
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1074761320304556
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The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability

1
1. scibot 01 May 2021
  
  in Public
  
  JAX:008875
  
  DOI: 10.1016/j.molcel.2021.04.009
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1097276521003142
Apr 2021
www.sciencedirect.com www.sciencedirect.com

High-content, targeted RNA-seq screening in organoids for drug discovery in colorectal cancer

1
1. scibot 21 Apr 2021
  
  in Public
  
  Stock No.: 008875
  
  DOI: 10.1016/j.celrep.2021.109026
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124721003405
www.sciencedirect.com www.sciencedirect.com

NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation

1
1. scibot 07 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.celrep.2021.108949
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:IMSR_JAX:008875
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sciencedirect.com/science/article/pii/S2211124721002631
Feb 2021
www.embopress.org www.embopress.org

MEX3A regulates Lgr5+ stem cell maintenance in the developing intestinal epithelium

1
1. scibot 24 Feb 2021
  
  in Public
  
  JAX:008875
  
  DOI: 10.15252/embr.201948938
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:008875
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embopress.org/doi/abs/10.15252/embr.201948938
Sep 2020
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Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine

1
1. scibot 04 Sep 2020
  
  in Public
  
  Lgr5eGFP-IRES-CreERT2: B6.129P2-Lgr5tm1(cre/ERT2)Cle/J
  
  DOI: 10.1016/j.celrep.2020.107937
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
  Curator comments: B6.129P2-Lgr5tm1(cre/ERT2)Cle/J Mus musculus IMSR Cat# JAX:008875
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124720309189
www.sciencedirect.com www.sciencedirect.com

Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription

1
1. scibot 03 Sep 2020
  
  in Public
  
  JAX# 8875
  
  DOI: 10.1016/j.stem.2020.03.002
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1934590920300941
www.sciencedirect.com www.sciencedirect.com

Cycling Stem Cells Are Radioresistant and Regenerate the Intestine

1
1. scibot 03 Sep 2020
  
  in Public
  
  Lgr5EGFP-IRES-CreERT2
  
  DOI: 10.1016/j.celrep.2020.107952
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
  Curator comments: B6.129P2-Lgr5tm1(cre/ERT2)Cle/J Mus musculus IMSR Cat# JAX:008875
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124720309335
www.sciencedirect.com www.sciencedirect.com

A Map of Toll-like Receptor Expression in the Intestinal Epithelium Reveals Distinct Spatial, Cell Type-Specific, and Temporal Patterns

1
1. scibot 03 Sep 2020
  
  in Public
  
  8875
  
  DOI: 10.1016/j.immuni.2018.07.016
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
  Curator comments: B6.129P2-Lgr5tm1(cre/ERT2)Cle/J Mus musculus IMSR Cat# JAX:008875
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1074761318303364
onlinelibrary.wiley.com onlinelibrary.wiley.com

UHRF2 promotes intestinal tumorigenesis through stabilization of TCF4 mediated Wnt/β‐catenin signaling

1
1. scibot 03 Sep 2020
  
  in Public
  
  Lgr5‐EGFP‐ires‐CreERT2
  
  DOI: 10.1002/ijc.33036
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
  Curator comments: B6.129P2-Lgr5tm1(cre/ERT2)Cle/J Mus musculus IMSR Cat# JAX:008875
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Missing
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onlinelibrary.wiley.com/doi/10.1002/ijc.33036
Jan 2020
www.sciencedirect.com www.sciencedirect.com

PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.stem.2019.08.017
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1934590919303844
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FXR Regulates Intestinal Cancer Stem Cell Proliferation

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:008875
  
  DOI: 10.1016/j.cell.2019.01.036
  
  Resource: (IMSR Cat# JAX_008875,RRID:IMSR_JAX:008875)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867419300996
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity

1
1. scibot 05 Nov 2018
  
  in Public
  
  008875
  
  Curator: @bandrow
  
  Resource used:
  
  RRID:IMSR_JAX:008875
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Missing
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URL

ncbi.nlm.nih.gov/pmc/articles/PMC6104739/
www.sciencedirect.com www.sciencedirect.com

Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration

1
1. scibot 05 Nov 2018
  
  in Public
  
  JAX:008875
  
  Resource used:
  
  RRID:IMSR_JAX:008875
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
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  RRID:IMSR_JAX:008875
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sciencedirect.com/science/article/pii/S1934590918303527
www.sciencedirect.com www.sciencedirect.com

Morphogenesis and Compartmentalization of the Intestinal Crypt

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:008875
  
  Resource used:
  
  RRID:IMSR_JAX:008875
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
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  RRID:IMSR_JAX:008875
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sciencedirect.com/science/article/pii/S1534580718302442
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:008875
  
  Curator: @evieth
  
  Resource used:
  
  RRID:IMSR_JAX:008875
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC5896954/
www.cell.com www.cell.com

Calorie Restriction Governs Intestinal Epithelial Regeneration through Cell-Autonomous Regulation of mTORC1 in Reserve Stem Cells

1
1. scibot 05 Nov 2018
  
  in Public
  
  Lgr5-eGFP-IRES-CreERT2(Jax mice strain 008875
  
  Curator: @bandrow
  
  Resource used:
  
  RRID:IMSR_JAX:008875
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
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  RRID:IMSR_JAX:008875
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cell.com/stem-cell-reports/pdfExtended/S2213-6711(18)30052-3
www.sciencedirect.com www.sciencedirect.com

Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression

1
1. scibot 05 Nov 2018
  
  in Public
  
  JAX:008875
  
  Resource used:
  
  RRID:IMSR_JAX:008875
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
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sciencedirect.com/science/article/pii/S1934590917305040
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Dynamic Reorganization of Chromatin Accessibility Signatures during Dedifferentiation of Secretory Precursors into Lgr5+ Intestinal Stem Cells

1
1. scibot 09 Nov 2017
  
  in Public
  
  Mouse: Lgr5Cre-GfpThe Jackson Laboratory008875
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:008875
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1934590917301662
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Lgr5 Marks Post-Mitotic, Lineage Restricted Cerebellar Granule Neurons during Postnatal Development

3
1. scibot 09 Nov 2017
  
  in Public
  
  IMSR_JAX:008875
  
  Curator: @gabimpine
  
  Curator note: I can't find this one
  
  Resource used:
  
  RRID:IMSR_JAX:008875
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:008875 RRIDCUR:InsufficientMetadata RRIDCUR:Unresolved
2. scibot 08 Nov 2017
  
  in Public
  
  IMSR_JAX:008875
  
  Curator: @gabimpine
  
  Curator note: I can't find this one
  
  Resource used:
  
  RRID:IMSR_JAX:008875
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:008875 RRIDCUR:InsufficientMetadata RRIDCUR:Unresolved
3. scibot 08 Nov 2017
  
  in Public
  
  IMSR_JAX:008875
  
  Curator: @gabimpine
  
  Curator note: I can't find this one
  
  Resource used:
  
  RRID:IMSR_JAX:008875
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:008875 RRIDCUR:InsufficientMetadata RRIDCUR:Unresolved
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ncbi.nlm.nih.gov/pmc/articles/PMC4262395/
www.sciencedirect.com www.sciencedirect.com

Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming

1
1. scibot 08 Nov 2017
  
  in Public
  
  008875
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:008875
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1934590917303387
www.sciencedirect.com www.sciencedirect.com

Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition

1
1. scibot 08 Nov 2017
  
  in Public
  
  008875
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:008875
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1934590916303599
www.sciencedirect.com www.sciencedirect.com

Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity

1
1. scibot 08 Nov 2017
  
  in Public
  
  Jax #008875
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:008875
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1934590917302400
www.sciencedirect.com www.sciencedirect.com

Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity

1
1. scibot 08 Nov 2017
  
  in Public
  
  JAX: 008875
  
  Curator: @gabimpine
  
  Resource used:
  
  RRID:IMSR_JAX:008875
  
  SciCrunch record: RRID:IMSR_JAX:008875
  
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  RRID:IMSR_JAX:008875 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2405471216302654

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