Hypothesis

31 Matching Annotations

Jan 2026
www.biorxiv.org www.biorxiv.org

Second-order regulation: IFN-γ suppresses IL-17A-mediated neutrophilic inflammation

1
1. scibot 15 Jan 2026
  
  in Public
  
  012606
  
  DOI: 10.64898/2026.01.05.697792
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

biorxiv.org/content/10.64898/2026.01.05.697792v1
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

STAT-independent functions of Janus kinases 1 and 2 are obligatory for the postnatal development of mammary epithelial ducts

1
1. scibot 18 Dec 2025
  
  in Public
  
  Jackson LaboratoryStrain #: 012606
  
  DOI: 10.1016/j.celrep.2025.116703
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

sciencedirect.com:5037/science/article/pii/S2211124725014755
Nov 2025
www.biorxiv.org www.biorxiv.org

The antiviral Interferon pathway drives astrocyte aging and motor decline

1
1. scibot 18 Nov 2025
  
  in Public
  
  RRID:IMSR_JAX:012606
  
  DOI: 10.1101/2025.11.12.688147
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

biorxiv.org/content/10.1101/2025.11.12.688147v1
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A recombinant Cedar virus preclinical model that recapitulates neurological features of henipavirus disease

2
1. scibot 16 Oct 2025
  
  in Public
  
  RRID:IMSR_JAX:012606
  
  DOI: 10.1016/j.isci.2025.113571
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
  What is this?
  
  RRID:IMSR_JAX:012606
2. scibot 16 Oct 2025
  
  in Public
  
  RRID:IMSR_JAX
  
  DOI: 10.1016/j.isci.2025.113571
  
  Resource: None
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRIDCUR:Unresolved RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

RRIDCUR:Unresolved

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12510183/
Sep 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225018322-main-html.html

1
1. scibot 16 Sep 2025
  
  in Public
  
  RRID:IMSR_JAX:012606
  
  DOI: 10.1016
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

52.53.155.43/327d1b517863f45db90d80fdf4807173493a9a9f/1-s2.0-S2589004225018322-main-html.html
Jun 2025
www.sciencedirect.com www.sciencedirect.com

Transcription factor T-bet regulates the maintenance and differentiation potential of lymph node and lung effector memory B cell subsets

1
1. scibot 24 Jun 2025
  
  in Public
  
  RRID:IMSR_JAX:012606
  
  DOI: 10.1016/j.immuni.2025.05.021
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

sciencedirect.com/science/article/pii/S1074761325002420
Nov 2024
www.sciencedirect.com www.sciencedirect.com

Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair

1
1. scibot 16 Nov 2024
  
  in Public
  
  RRID:IMSR_JAX:012606
  
  DOI: 10.1016/j.cell.2024.10.010
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

sciencedirect.com/science/article/pii/S0092867424011589
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Antiviral Functions of Type I and Type III Interferons in the Olfactory Epithelium

1
1. scibot 07 Nov 2024
  
  in Public
  
  12606
  
  DOI: 10.3390/biom13121762
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @AleksanderDrozdz
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC10741941/
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38

1
1. scibot 16 Jul 2024
  
  in Public
  
  Jackson LabsCat. #012606
  
  DOI: 10.1016/j.celrep.2024.114502
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724008313
May 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Lack of the IFN-γ signal leads to lethal Orientia tsutsugamushi infection in mice with skin eschar lesions

1
1. scibot 22 May 2024
  
  in Public
  
  012606
  
  DOI: 10.1371/journal.ppat.1012020
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  DOI:10.1371/journal.ppat.1012020 RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

DOI:10.1371/journal.ppat.1012020

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11125519/
Apr 2024
www.biorxiv.org www.biorxiv.org

Lack of the IFN-γ signal leads to lethal Orientia tsutsugamushi infection in mice with skin eschar lesions

1
1. scibot 02 Apr 2024
  
  in Public
  
  012606
  
  DOI: 10.1101/2024.02.05.578851
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

biorxiv.org/content/10.1101/2024.02.05.578851v1
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection

1
1. scibot 02 Feb 2024
  
  in Public
  
  JAX:012606
  
  DOI: 10.1016/j.chom.2024.01.002
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

sciencedirect.com/science/article/pii/S1931312824000064
Jan 2024
www.sciencedirect.com www.sciencedirect.com

T helper 1 effector memory CD4+ T cells protect the skin from poxvirus infection

1
1. scibot 04 Jan 2024
  
  in Public
  
  012606
  
  DOI: 10.1016/j.celrep.2023.112407
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

sciencedirect.com/science/article/pii/S2211124723004187
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Age-associated features of norovirus infection analysed in mice

1
1. scibot 03 Jan 2024
  
  in Public
  
  012606
  
  DOI: 10.1038/s41564-023-01383-1
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC10484054/
Dec 2023
www.cell.com www.cell.com

Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice

1
1. scibot 19 Dec 2023
  
  in Public
  
  RRID:IMSR_JAX:012606
  
  DOI: 10.1016/j.devcel.2023.11.013
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

cell.com/developmental-cell/fulltext/S1534-5807(23)00611-1
Sep 2023
www.nature.com www.nature.com

Blockade of interferon signaling decreases gut barrier integrity and promotes severe West Nile virus disease

1
1. scibot 29 Sep 2023
  
  in Public
  
  RRID:IMSR_JAX:01260683
  
  DOI: 10.1038/s41467-023-41600-3
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_JAX:012606
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RRIDCUR:Unresolved

RRID:IMSR_JAX:012606

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scibot

URL

nature.com/articles/s41467-023-41600-3
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity

1
1. scibot 10 Nov 2022
  
  in Public
  
  RRID:IMSR_JAX:012606
  
  DOI: 10.1016/j.celrep.2022.111593
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722014589
Sep 2022
www.jneurosci.org www.jneurosci.org

STAT1 contributes to microglial/macrophage inflammation and neurological dysfunction in a mouse model of traumatic brain injury

1
1. scibot 29 Sep 2022
  
  in Public
  
  RRID:IMSR_JAX:012606
  
  DOI: 10.1523/JNEUROSCI.0682-22.2022
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

jneurosci.org/content/42/39/7466
May 2022
www.sciencedirect.com www.sciencedirect.com

Antigen presentation safeguards the integrity of the hematopoietic stem cell pool

1
1. scibot 06 May 2022
  
  in Public
  
  JAX:012606
  
  DOI: 10.1016/j.stem.2022.04.007
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

sciencedirect.com/science/article/pii/S1934590922001606
Apr 2022
www.sciencedirect.com www.sciencedirect.com

ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection

1
1. scibot 21 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:012606
  
  DOI: 10.1016/j.celrep.2022.110715
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722004764
Feb 2022
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction

1
1. scibot 23 Feb 2022
  
  in Public
  
  RRID:IMSR_JAX:012606
  
  DOI: 10.1016/j.celrep.2022.110420
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

pubmed.ncbi.nlm.nih.gov/35196494/
www.sciencedirect.com www.sciencedirect.com

Interferon-β acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation

2
1. scibot 11 Feb 2022
  
  in Public
  
  012606
  
  DOI: 10.1016/j.immuni.2022.01.011
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
  What is this?
  
  RRID:IMSR_JAX:012606
2. scibot 11 Feb 2022
  
  in Public
  
  012606
  
  DOI: 10.1016/j.immuni.2022.01.011
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

sciencedirect.com/science/article/pii/S1074761322000401
May 2021
www.sciencedirect.com www.sciencedirect.com

Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation

1
1. scibot 19 May 2021
  
  in Public
  
  Cat.# 012606
  
  DOI: 10.1016/j.chom.2021.04.004
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
  What is this?
  
  RRID:IMSR_JAX:012606 RRIDCUR:Missing
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RRID:IMSR_JAX:012606

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1931312821001803
www.sciencedirect.com www.sciencedirect.com

An activity-dependent determinant of synapse elimination in the mammalian brain

1
1. scibot 08 May 2021
  
  in Public
  
  RRID:IMSR_JAX:012606
  
  DOI: 10.1016/j.neuron.2021.03.006
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

sciencedirect.com/science/article/pii/S0896627321001549
Apr 2021
www.sciencedirect.com www.sciencedirect.com

The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis

1
1. scibot 24 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:012606
  
  DOI: 10.1016/j.cell.2020.06.029
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
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  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

sciencedirect.com/science/article/pii/S0092867420308060
Sep 2020
www.sciencedirect.com www.sciencedirect.com

A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies

1
1. scibot 07 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:012606
  
  DOI: 10.1016/j.cell.2020.06.011
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S009286742030742X
Jan 2020
www.sciencedirect.com www.sciencedirect.com

RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer

1
1. scibot 12 Jan 2020
  
  in Public
  
  JAX:012606
  
  DOI: 10.1016/j.ccell.2018.10.006
  
  Resource: (IMSR Cat# JAX_012606,RRID:IMSR_JAX:012606)
  
  Curator: @Jmenke
  
  SciCrunch record: JAX:012606
  
  What is this?
  
  RRID:IMSR_JAX:012606 RRIDCUR:Validated
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RRID:IMSR_JAX:012606

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1535610818304720
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1

1
1. scibot 05 Nov 2018
  
  in Public
  
  012606
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:012606
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:012606 RRIDCUR:Missing
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RRID:IMSR_JAX:012606

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1074761318300840
www.sciencedirect.com www.sciencedirect.com

Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:012606
  
  Resource used:
  
  RRID:IMSR_JAX:012606
  
  SciCrunch record: RRID:IMSR_JAX:012606
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:012606
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RRID:IMSR_JAX:012606

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scibot

URL

sciencedirect.com/science/article/pii/S0896627317310851