46 Matching Annotations
  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Customised design of antisense oligonucleotides targeting EGFR driver mutants for personalised treatment of non-small cell lung cancer
    1
    1. scibot 25 Sep 2024
      RRID:IMSR_JAX

      DOI: 10.1016/j.ebiom.2024.105356

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    sciencedirect.com/science/article/pii/S235239642400392X
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Psoriatic arthritis subtypes are phenocopied in humanized mice
    1
    1. scibot 15 Sep 2024
      RRID:IMSR_JAX:013062

      DOI: 10.1172/jci.insight.178213

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    ncbi.nlm.nih.gov/pmc/articles/PMC11383598/
  4. Jun 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    B7-H3–Targeting Chimeric Antigen Receptors Epstein-Barr Virus–specific T Cells Provides a Tumor Agnostic Off-The-Shelf Therapy Against B7-H3–positive Solid Tumors
    1
    1. scibot 09 Jun 2024
      RRID 013062

      DOI: 10.1158/2767-9764.CRC-23-0538

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      Curator: @evieth

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      DOI:10.1158/2767-9764.CRC-23-0538 RRID:IMSR_JAX:013062
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    ncbi.nlm.nih.gov/pmc/articles/PMC11149603/
  6. Apr 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers
    1
    1. scibot 26 Apr 2024
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.ccell.2024.04.004

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    sciencedirect.com/science/article/pii/S1535610824001284
  8. www.sciencedirect.com www.sciencedirect.com
    Human anti-PSCA CAR macrophages possess potent antitumor activity against pancreatic cancer
    1
    1. scibot 25 Apr 2024
      Jackson LaboratoryStrain# 013062

      DOI: 10.1016/j.stem.2024.03.018

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @abever99

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    sciencedirect.com/science/article/pii/S1934590924001243
  9. Mar 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bacteriophage therapy for the treatment of Mycobacterium tuberculosis infections in humanized mice
    1
    1. scibot 12 Mar 2024
      RRID:IMSR_JAX:013062

      DOI: 10.1038/s42003-024-06006-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10924958/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel type of monocytic leukemia stem cell revealed by the clinical use of venetoclax-based therapy
    1
    1. scibot 06 Mar 2024
      RRID:IMSR_JAX:013062

      DOI: 10.1158/2159-8290.CD-22-1297

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    ncbi.nlm.nih.gov/pmc/articles/PMC10527971/
  12. www.sciencedirect.com www.sciencedirect.com
    The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression
    1
    1. scibot 01 Mar 2024
      The Jackson Laboratory13062

      DOI: 10.1016/j.cell.2024.01.048

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      Curator: @abever99

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    sciencedirect.com/science/article/pii/S009286742400117X
  13. Feb 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Peptide-scFv antigen recognition domains effectively confer CAR T cell multiantigen specificity
    1
    1. scibot 13 Feb 2024
      The Jackson LaboratoryCat#013062

      DOI: 10.1016/j.xcrm.2024.101422

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @abever99

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    sciencedirect.com/science/article/pii/S2666379124000454
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML
    1
    1. scibot 02 Feb 2024
      RRID:IMSR_JAX:013062

      DOI: 10.1158/1078-0432.CCR-22-3929

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524644/
  16. Jan 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death
    1
    1. scibot 11 Jan 2024
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.cell.2023.12.015

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    sciencedirect.com/science/article/pii/S0092867423013478
  18. Dec 2023
  19. www.sciencedirect.com www.sciencedirect.com
    SON is an essential m6A target for hematopoietic stem cell fate
    1
    1. scibot 17 Dec 2023
      The Jackson LaboratoryStrain # 013062

      DOI: 10.1016/j.stem.2023.11.006

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S1934590923003983
  20. Nov 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
    1
    1. scibot 22 Nov 2023
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.xcrm.2023.101290

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      Curator: @scibot

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    sciencedirect.com/science/article/pii/S2666379123004846
  22. Oct 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Cooperative CAR targeting to selectively eliminate AML and minimize escape
    1
    1. scibot 13 Oct 2023
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.ccell.2023.09.010

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    sciencedirect.com/science/article/pii/S1535610823003264
  24. Sep 2023
  25. www.sciencedirect.com www.sciencedirect.com
    CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax
    1
    1. scibot 19 Sep 2023
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.celrep.2023.113084

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    sciencedirect.com/science/article/pii/S2211124723010951
  26. Apr 2023
  27. aacrjournals.org aacrjournals.org
    Dual mTORC1/2 inhibition synergistically enhances AML cell death in combination with the BCL2 antagonist venetoclax
    1
    1. scibot 21 Apr 2023
      RRID:IMSR_JAX:013062

      DOI: 10.1158/1078-0432.CCR-22-2729

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @scibot

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    aacrjournals.org/clincancerres/article/29/7/1332/718764/Dual-mTORC1-2-Inhibition-Synergistically-Enhances
  28. Mar 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutaminase inhibition in combination with azacytidine in myelodysplastic syndromes: Clinical efficacy and correlative analyses
    1
    1. scibot 18 Mar 2023
      RRID:IMSR_JAX

      DOI: 10.21203/rs.3.rs-2518774/v1

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @evieth

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      RRID:IMSR_JAX:013062 RRIDCUR:Unresolved
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    ncbi.nlm.nih.gov/pmc/articles/PMC9980221/
  30. Feb 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Reversal of malignant ADAR1 splice isoform switching with Rebecsinib
    1
    1. scibot 17 Feb 2023
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.stem.2023.01.008

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

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    sciencedirect.com/science/article/pii/S1934590923000085
  32. www.biorxiv.org www.biorxiv.org
    Bacteriophage therapy for the treatment of Mycobacterium tuberculosis infections in humanized mice
    1
    1. scibot 07 Feb 2023
      RRID:IMSR_JAX:013062

      DOI: 10.1101/2023.01.23.525188

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @scibot

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    biorxiv.org/content/10.1101/2023.01.23.525188v1
  33. Dec 2022
  34. www.sciencedirect.com www.sciencedirect.com
    Expression of inducible factors reprograms CAR-T cells for enhanced function and safety
    1
    1. scibot 13 Dec 2022
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.ccell.2022.11.006

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    sciencedirect.com/science/article/pii/S1535610822005530
  35. Nov 2022
  36. www.embopress.org www.embopress.org
    Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T-cell lymphoma
    1
    1. scibot 12 Nov 2022
      RRID:IMSR_JAX:013062

      DOI: 10.15252/emmm.202115200

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    embopress.org/doi/10.15252/emmm.202115200
  37. Apr 2022
  38. aacrjournals.org aacrjournals.org
    Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia
    1
    1. scibot 05 Apr 2022
      RRID:IMSR_JAX:013062

      DOI: 10.1158/2159-8290.CD-21-0692

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    aacrjournals.org/cancerdiscovery/article/12/4/1106/689604/Subversion-of-Serotonin-Receptor-Signaling-in
  39. Mar 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Lamin B1 deletion in myeloid neoplasms causes nuclear anomaly and altered hematopoietic stem cell function
    1
    1. scibot 18 Mar 2022
      Jackson labscat#: 013062

      DOI: 10.1016/j.stem.2022.02.010

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @sophiastull

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    sciencedirect.com/science/article/pii/S1934590922000613
  41. www.sciencedirect.com www.sciencedirect.com
    Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML
    1
    1. scibot 09 Mar 2022
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.celrep.2022.110481

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    sciencedirect.com/science/article/pii/S2211124722002145
  42. www.sciencedirect.com www.sciencedirect.com
    Immunodepletion of MDSC by AMV564, a novel bivalent, bispecific CD33/CD3 T cell engager, ex vivo in MDS and melanoma
    1
    1. scibot 04 Mar 2022
      RRID:IMSR_JAX:013062Info

      DOI: 10.1016/j.ymthe.2022.02.005

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      Curator: @sophiastull

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      RRID:IMSR_JAX:013062 RRIDCUR:Unresolved
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    sciencedirect.com/science/article/pii/S1525001622000880
  43. Feb 2022
  44. www.sciencedirect.com www.sciencedirect.com
    An oncogenic enhancer encodes selective selenium dependency in AML
    1
    1. scibot 02 Feb 2022
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.stem.2022.01.003

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    sciencedirect.com/science/article/pii/S1934590922000030
  45. Jan 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions
    1
    1. scibot 16 Jan 2022
      The Jackson LaboratoryCat# 013062

      DOI: 10.1016/j.crmeth.2021.100153

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @sophiastull

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    sciencedirect.com/science/article/pii/S2667237521002307
  47. Aug 2021
  48. www.sciencedirect.com www.sciencedirect.com
    TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate
    1
    1. scibot 04 Aug 2021
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.stem.2021.07.003

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    sciencedirect.com/science/article/pii/S1934590921002885
  49. Jul 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells
    1
    1. scibot 30 Jul 2021
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.ccell.2018.10.005

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      Curator: @Jmenke

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      RRIDCUR:Validated RRID:IMSR_JAX:013062
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    ncbi.nlm.nih.gov/pmc/articles/PMC6280965/
  51. www.sciencedirect.com www.sciencedirect.com
    JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells
    1
    1. scibot 27 Jul 2021
      013062

      DOI: 10.1016/j.ccell.2018.10.008

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      RRIDCUR:Missing RRID:IMSR_JAX:013062
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    sciencedirect.com/science/article/pii/S1535610818304744
  52. www.sciencedirect.com www.sciencedirect.com
    AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells
    1
    1. scibot 27 Jul 2021
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.stem.2018.05.021

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    sciencedirect.com/science/article/pii/S193459091830239X
  53. Jun 2021
  54. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms
    1
    1. scibot 29 Jun 2021
      RRID:IMSR_JAX:013062

      DOI: 10.1158/2159-8290.CD-20-1353

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    cancerdiscovery.aacrjournals.org/content/11/6/1398
  55. May 2021
  56. www.sciencedirect.com www.sciencedirect.com
    Coexpression of CD71 and CD117 Identifies an Early Unipotent Neutrophil Progenitor Population in Human Bone Marrow
    1
    1. scibot 15 May 2021
      Stock No: 013062

      DOI: 10.1016/j.immuni.2020.07.017

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      Curator: @Naa003

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      RRID:IMSR_JAX:013062 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1074761320303241
  57. www.sciencedirect.com www.sciencedirect.com
    Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells
    1
    1. scibot 09 May 2021
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.stem.2020.07.021

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    sciencedirect.com/science/article/pii/S1934590920303593
  58. Apr 2021
  59. rupress.org rupress.org
    Human KIT+ myeloid cells facilitate visceral metastasis by melanoma
    1
    1. scibot 24 Apr 2021
      JAX:013062

      DOI: 10.1084/jem.20182163

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    rupress.org/jem/article/218/6/e20182163/211995/Human-KIT-myeloid-cells-facilitate-visceral
  60. www.sciencedirect.com www.sciencedirect.com
    Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity
    1
    1. scibot 17 Apr 2021
      Cat# 013062

      DOI: 10.1016/j.ccell.2020.05.020

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:013062

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      RRIDCUR:Missing RRID:IMSR_JAX:013062
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    sciencedirect.com/science/article/pii/S1535610820302701
  61. Mar 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells
    1
    1. scibot 28 Mar 2021
      RRID:IMSR_JAX:013062

      DOI: 10.1158/2643-3230.BCD-20-0161

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:013062

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      RRID:IMSR_JAX:013062
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    ncbi.nlm.nih.gov/pmc/articles/PMC7610449/
  63. Jan 2021
  64. www.sciencedirect.com www.sciencedirect.com
    Enriching for human acute myeloid leukemia stem cells using reactive oxygen species-based cell sorting
    1
    1. scibot 05 Jan 2021
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.xpro.2020.100248

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:013062

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      RRID:IMSR_JAX:013062 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2666166720302355
  65. Sep 2020
  66. www.sciencedirect.com www.sciencedirect.com
    RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia
    1
    1. scibot 26 Sep 2020
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.stem.2020.04.009

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @ethanbadger

      SciCrunch record: RRID:IMSR_JAX:013062

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      RRIDCUR:Validated RRID:IMSR_JAX:013062
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    sciencedirect.com/science/article/pii/S193459092030148X
  67. www.sciencedirect.com www.sciencedirect.com
    Therapeutic Targeting of Follicular T Cells with Chimeric Antigen Receptor-Expressing Natural Killer Cells
    1
    1. scibot 07 Sep 2020
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.xcrm.2020.100003

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @ethanbadger

      SciCrunch record: RRID:IMSR_JAX:013062

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      RRID:IMSR_JAX:013062 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2666379120300033
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of an Early Unipotent Neutrophil Progenitor with Pro-tumoral Activity in Mouse and Human Bone Marrow
    1
    1. scibot 03 Sep 2020
      013062

      DOI: 10.1016/j.celrep.2018.07.097

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:013062

      Curator comments: NOD.Cg-Prkdcscid Il2rgtm1Wjl Tg(CMV-IL3,CSF2,KITLG)1Eav/MloySzJ Mus musculus IMSR Cat# JAX:013062

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      RRID:IMSR_JAX:013062 RRIDCUR:Missing
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    ncbi.nlm.nih.gov/pmc/articles/PMC6542273/
  69. Aug 2020
  70. www.sciencedirect.com www.sciencedirect.com
    CBFβ-SMMHC Affects Genome-wide Polycomb Repressive Complex 1 Activity in Acute Myeloid Leukemia
    1
    1. scibot 17 Aug 2020
      Mouse: NSG-SGM3 (NOD.Cg-Prkdcscid Il2rgtm1Wjl Tg(CMV-IL3,CSF2,KITLG)1Eav/MloySzJ)

      DOI: 10.1016/j.celrep.2019.12.026

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @ethanbadger

      SciCrunch record: RRID:IMSR_JAX:013062

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      RRIDCUR:Missing RRID:IMSR_JAX:013062
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    sciencedirect.com/science/article/pii/S2211124719316766
  71. Jan 2020
  72. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      JAX:013062

      DOI: 10.1016/j.stem.2018.12.003

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @ethanbadger

      SciCrunch record: JAX:013062

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      RRID:IMSR_JAX:013062 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1934590918305939
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:013062

      DOI: 10.1016/j.ccell.2018.10.005

      Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)

      Curator: @Jmenke

      SciCrunch record: RRID:IMSR_JAX:013062

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      RRID:IMSR_JAX:013062 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6280965/
  74. Nov 2018
  75. www.sciencedirect.com www.sciencedirect.com
    Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance
    1
    1. scibot 05 Nov 2018
      013062

      Curator: @Jmenke

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      RRID:IMSR_JAX:013062

      SciCrunch record: RRID:IMSR_JAX:013062

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:IMSR_JAX:013062 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1934590918303874
  76. www.sciencedirect.com www.sciencedirect.com
    SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function
    1
    1. scibot 05 Nov 2018
      013062

      Curator: @Jmenke

      Resource used:

      RRID:IMSR_JAX:013062

      SciCrunch record: RRID:IMSR_JAX:013062

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:IMSR_JAX:013062 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1934590918303850