Hypothesis

18 Matching Annotations

Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cell-intrinsic regulation of epilepsy-associated pathology by mTORC1 and mTORC2

1
1. scibot 29 Apr 2026
  
  in Public
  
  RRID:IMSR_JAX:013188
  
  DOI: 10.1523/JNEUROSCI.1211-25.2026
  
  Resource: (IMSR Cat# JAX_013188,RRID:IMSR_JAX:013188)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
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  RRID:IMSR_JAX:013188
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RRID:IMSR_JAX:013188

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC13113615/
Dec 2025
www.sciencedirect.com www.sciencedirect.com

Early postsynaptic potentiation in hippocampal somatostatin interneurons is mTORC1-dependent and disrupted in Fmr1−/y mice

1
1. scibot 25 Dec 2025
  
  in Public
  
  RRID:IMSR_JAX:013188
  
  DOI: 10.1016/j.neuroscience.2025.12.033
  
  Resource: (IMSR Cat# JAX_013188,RRID:IMSR_JAX:013188)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  What is this?
  
  RRID:IMSR_JAX:013188
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RRID:IMSR_JAX:013188

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scibot

URL

sciencedirect.com/science/article/pii/S0306452225011923
May 2025
www.sciencedirect.com www.sciencedirect.com

Lymphatic endothelial mTORC1 instructs metabolic and developmental signaling during lymphangiogenesis

1
1. scibot 17 May 2025
  
  in Public
  
  JAX:013188
  
  DOI: 10.1016/j.devcel.2025.04.012
  
  Resource: (IMSR Cat# JAX_013188,RRID:IMSR_JAX:013188)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  What is this?
  
  RRID:IMSR_JAX:013188
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RRID:IMSR_JAX:013188

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scibot

URL

sciencedirect.com/science/article/pii/S1534580725002503
Aug 2024
www.cell.com www.cell.com

Calorie Restriction Governs Intestinal Epithelial Regeneration through Cell-Autonomous Regulation of mTORC1 in Reserve Stem Cells

1
1. scibot 02 Aug 2024
  
  in Public
  
  Raptorfloxed (Jax mice strain 013188
  
  DOI: 10.1016/s2352-0779(18)30052-9
  
  Resource: (IMSR Cat# JAX_013188,RRID:IMSR_JAX:013188)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  What is this?
  
  RRID:IMSR_JAX:013188
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RRID:IMSR_JAX:013188

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scibot

URL

cell.com/stem-cell-reports/pdfExtended/S2213-6711(18)30052-3
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Dietary fructose-mediated adipocyte metabolism drives antitumor CD8+ T cell responses

1
1. scibot 27 Oct 2023
  
  in Public
  
  RRID:IMSR_JAX:013188
  
  DOI: 10.1016/j.cmet.2023.09.011
  
  Resource: (IMSR Cat# JAX_013188,RRID:IMSR_JAX:013188)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  What is this?
  
  RRID:IMSR_JAX:013188
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RRID:IMSR_JAX:013188

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scibot

URL

sciencedirect.com/science/article/pii/S1550413123003674
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Disruption of mTORC1 rescues neuronal overgrowth and synapse function dysregulated by Pten loss

1
1. scibot 03 Nov 2022
  
  in Public
  
  RRID:IMSR_JAX:013188
  
  DOI: 10.1016/j.celrep.2022.111574
  
  Resource: (IMSR Cat# JAX_013188,RRID:IMSR_JAX:013188)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  What is this?
  
  RRID:IMSR_JAX:013188
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RRID:IMSR_JAX:013188

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722014358
Jul 2022
www.sciencedirect.com www.sciencedirect.com

mTORC1 signaling in antigen-presenting cells of the skin restrains CD8+ T cell priming

1
1. scibot 06 Jul 2022
  
  in Public
  
  JAX:013188
  
  DOI: 10.1016/j.celrep.2022.111032
  
  Resource: (IMSR Cat# JAX_013188,RRID:IMSR_JAX:013188)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  What is this?
  
  RRID:IMSR_JAX:013188
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RRID:IMSR_JAX:013188

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722008269
Jun 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria

1
1. scibot 15 Jun 2022
  
  in Public
  
  RRID:IMSR_JAX:013188
  
  DOI: 10.7554/eLife.68598
  
  Resource: (IMSR Cat# JAX_013188,RRID:IMSR_JAX:013188)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  What is this?
  
  RRID:IMSR_JAX:013188
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RRID:IMSR_JAX:013188

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9183236/
May 2022
link.springer.com link.springer.com

Impact of Raptor and Rictor Deletion on Hippocampal Pathology Following Status Epilepticus

1
1. scibot 28 May 2022
  
  in Public
  
  RRID:IMSR_JAX:013188
  
  DOI: 10.1007/s12031-022-02030-w
  
  Resource: (IMSR Cat# JAX_013188,RRID:IMSR_JAX:013188)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  What is this?
  
  RRID:IMSR_JAX:013188
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RRID:IMSR_JAX:013188

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scibot

URL

link.springer.com/article/10.1007/s12031-022-02030-w
www.sciencedirect.com www.sciencedirect.com

Long-term potentiation at pyramidal cell to somatostatin interneuron synapses controls hippocampal network plasticity and memory

1
1. scibot 10 May 2022
  
  in Public
  
  JAX:013188
  
  DOI: 10.1016/j.isci.2022.104259
  
  Resource: (IMSR Cat# JAX_013188,RRID:IMSR_JAX:013188)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  What is this?
  
  RRID:IMSR_JAX:013188
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RRID:IMSR_JAX:013188

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scibot

URL

sciencedirect.com/science/article/pii/S2589004222005296
Oct 2021
www.sciencedirect.com www.sciencedirect.com

Functional heterogeneity of POMC neurons relies on mTORC1 signaling

1
1. scibot 13 Oct 2021
  
  in Public
  
  RRID:IMSR_JAX:013188
  
  DOI: 10.1016/j.celrep.2021.109800
  
  Resource: (IMSR Cat# JAX_013188,RRID:IMSR_JAX:013188)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  What is this?
  
  RRID:IMSR_JAX:013188
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RRID:IMSR_JAX:013188

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721012602
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation

1
1. scibot 08 Sep 2021
  
  in Public
  
  Stock No: 013188
  
  DOI: 10.1016/j.celrep.2021.109659
  
  Resource: (IMSR Cat# JAX_013188,RRID:IMSR_JAX:013188)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:013188
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RRID:IMSR_JAX:013188

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721011037
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Differential Roles of the mTOR-STAT3 Signaling in Dermal γδ T Cell Effector Function in Skin Inflammation

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:013188
  
  DOI: 10.1016/j.celrep.2019.05.019
  
  Resource: (IMSR Cat# JAX_013188,RRID:IMSR_JAX:013188)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  What is this?
  
  RRID:IMSR_JAX:013188 RRIDCUR:Validated
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RRID:IMSR_JAX:013188

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719306308
Sep 2020
www.jneurosci.org www.jneurosci.org

Regulation of Hippocampal Memory by mTORC1 in Somatostatin Interneurons

1
1. scibot 09 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:013188
  
  DOI: 10.1523/JNEUROSCI.0728-19.2019
  
  Resource: (IMSR Cat# JAX_013188,RRID:IMSR_JAX:013188)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:013188
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RRID:IMSR_JAX:013188

RRIDCUR:Validated

Annotators

scibot

URL

jneurosci.org/content/39/43/8439
Nov 2018
www.sciencedirect.com www.sciencedirect.com

mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma

1
1. scibot 05 Nov 2018
  
  in Public
  
  013188
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:013188
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:013188 RRIDCUR:Missing
Visit annotations in context

Tags

RRID:IMSR_JAX:013188

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580717308249
www.cell.com www.cell.com

Calorie Restriction Governs Intestinal Epithelial Regeneration through Cell-Autonomous Regulation of mTORC1 in Reserve Stem Cells

1
1. scibot 05 Nov 2018
  
  in Public
  
  Raptorfloxed (Jax mice strain 013188
  
  Curator: @bandrow
  
  Resource used:
  
  RRID:IMSR_JAX:013188
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:013188
Visit annotations in context

Tags

RRID:IMSR_JAX:013188

Annotators

scibot

URL

cell.com/stem-cell-reports/pdfExtended/S2213-6711(18)30052-3
Nov 2017
www.sciencedirect.com www.sciencedirect.com

The Kinase mTORC1 Promotes the Generation and Suppressive Function of Follicular Regulatory T Cells

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:IMSR_JAX:013188
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:013188
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:013188 RRIDCUR:Validated
Visit annotations in context

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RRID:IMSR_JAX:013188

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761317303692
www.sciencedirect.com www.sciencedirect.com

An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice

1
1. scibot 08 Nov 2017
  
  in Public
  
  IMSR_JAX:013188
  
  Curator: @ifroman
  
  Resource used:
  
  RRID:IMSR_JAX:013188
  
  SciCrunch record: RRID:IMSR_JAX:013188
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:013188 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:IMSR_JAX:013188

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590917300942