Hypothesis

18 Matching Annotations

Jan 2026
www.sciencedirect.com www.sciencedirect.com

Altered hepatic metabolism in Down syndrome

1
1. scibot 16 Jan 2026
  
  in Public
  
  RRID:IMSR_JAX013530
  
  DOI: 10.1016/j.celrep.2025.116835
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_JAX:013530
Visit annotations in context

Tags

RRID:IMSR_JAX:013530

RRIDCUR:Unresolved

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725016079
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Aberrant tissue mechanics and mechanotransduction during heart development in down syndrome

1
1. scibot 09 Dec 2025
  
  in Public
  
  JAX:013530
  
  DOI: 10.1016/j.jbiomech.2025.113103
  
  Resource: (IMSR Cat# JAX_013530,RRID:IMSR_JAX:013530)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRID:IMSR_JAX:013530
Visit annotations in context

Tags

RRID:IMSR_JAX:013530

Annotators

scibot

URL

sciencedirect.com:5037/science/article/pii/S0021929025006153
Nov 2025
www.sciencedirect.com www.sciencedirect.com

Generation of human nucleus basalis organoids with functional nbM-cortical cholinergic projections in transplanted assembloids

1
1. scibot 05 Nov 2025
  
  in Public
  
  Jackson Laboratory Cat_013530
  
  DOI: 10.1016/j.stem.2025.10.004
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_JAX:013530
Visit annotations in context

Tags

RRID:IMSR_JAX:013530

RRIDCUR:Unresolved

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590925003728
Aug 2025
52.53.155.43 52.53.155.43

ssrn-5392056-html.html

2
1. scibot 21 Aug 2025
  
  in Public
  
  RRID:IMSR JAX013530
  
  DOI: 10.2139/ssrn.5392056
  
  Resource: (IMSR Cat# JAX_013530,RRID:IMSR_JAX:013530)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRID:IMSR_JAX:013530
2. scibot 21 Aug 2025
  
  in Public
  
  JAX:013530
  
  DOI: 10.2139/ssrn.5392056
  
  Resource: (IMSR Cat# JAX_013530,RRID:IMSR_JAX:013530)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRID:IMSR_JAX:013530
Visit annotations in context

Tags

RRID:IMSR_JAX:013530

Annotators

scibot

URL

52.53.155.43/969cb0acb0f42ae5b2af48a318fee51aab354b08/ssrn-5392056-html.html
Jul 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225013914-main-html.html

1
1. scibot 17 Jul 2025
  
  in Public
  
  RRID:IMSR_JAX:013530
  
  DOI: 10.1016/j.isci.2025.113130
  
  Resource: (IMSR Cat# JAX_013530,RRID:IMSR_JAX:013530)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRID:IMSR_JAX:013530
Visit annotations in context

Tags

RRID:IMSR_JAX:013530

Annotators

scibot

URL

52.53.155.43/90007a778f462697c048df1da24432bb37ed810f/1-s2.0-S2589004225013914-main-html.html
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Hyperactivation of RAB5 disrupts the endosomal Rab cascade leading to endolysosomal dysregulation in Down syndrome: A necessary role for increased APP gene dose

1
1. scibot 17 May 2025
  
  in Public
  
  JAX:013530
  
  DOI: 10.1002/alz.70046
  
  Resource: (IMSR Cat# JAX_013530,RRID:IMSR_JAX:013530)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRID:IMSR_JAX:013530
Visit annotations in context

Tags

RRID:IMSR_JAX:013530

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12058456/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Antisense oligonucleotides directed against App and Rab5 normalized endosomal Rab activity and reversed DS‐AD‐linked degenerative phenotypes in the Dp16 mouse model of Down syndrome

1
1. scibot 17 May 2025
  
  in Public
  
  JAX:013530
  
  DOI: 10.1002/alz.70022
  
  Resource: (IMSR Cat# JAX_013530,RRID:IMSR_JAX:013530)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRID:IMSR_JAX:013530
Visit annotations in context

Tags

RRID:IMSR_JAX:013530

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12058459/
May 2024
www.sciencedirect.com www.sciencedirect.com

Integrative multi-omic analysis reveals conserved cell-projection deficits in human Down syndrome brains

1
1. scibot 30 May 2024
  
  in Public
  
  RRID:IMSR_JAX:013530
  
  DOI: 10.1016/j.neuron.2024.05.002
  
  Resource: (IMSR Cat# JAX_013530,RRID:IMSR_JAX:013530)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRID:IMSR_JAX:013530
Visit annotations in context

Tags

RRID:IMSR_JAX:013530

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627324003295
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

“Heterogeneous subpopulations of GABAAR-responding neurons coexist across neuronal networks scales and developmental stages in health and disease”

1
1. scibot 03 Apr 2024
  
  in Public
  
  RRID:IMSR_JAX:013530
  
  DOI: 10.1016/j.isci.2024.109438
  
  Resource: (IMSR Cat# JAX_013530,RRID:IMSR_JAX:013530)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRID:IMSR_JAX:013530
Visit annotations in context

Tags

RRID:IMSR_JAX:013530

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10966311/
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Down Syndrome is Associated with Altered Frequency and Functioning of Tracheal Multiciliated Cells, and Response to Influenza Virus Infection

1
1. scibot 10 Aug 2023
  
  in Public
  
  RRID:IMSR_JAX:013530
  
  DOI: 10.1016/j.isci.2023.107361
  
  Resource: (IMSR Cat# JAX_013530,RRID:IMSR_JAX:013530)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRID:IMSR_JAX:013530
Visit annotations in context

Tags

RRID:IMSR_JAX:013530

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10405068/
Jun 2023
52.53.155.43 52.53.155.43

Interferon hyperactivity impairs cardiogenesis in Down syndrome via downregulation of canonical Wnt signaling

3
1. scibot 10 Jun 2023
  
  in Public
  
  JAX:013530
  
  DOI: 10.1016/j.isci.2023.107012
  
  Resource: (IMSR Cat# JAX_013530,RRID:IMSR_JAX:013530)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRID:IMSR_JAX:013530
2. scibot 10 Jun 2023
  
  in Public
  
  RRID:IMSR_JAX013
  
  DOI: 10.1016/j.isci.2023.107012
  
  Resource: (IMSR Cat# JAX_013530,RRID:IMSR_JAX:013530)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRID:IMSR_JAX:013530 RRIDCUR:Unresolved
3. scibot 10 Jun 2023
  
  in Public
  
  RRID:IMSR_JAX013530
  
  DOI: 10.1016/j.isci.2023.107012
  
  Resource: (IMSR Cat# JAX_013530,RRID:IMSR_JAX:013530)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRID:IMSR_JAX:013530 RRIDCUR:Unresolved
Visit annotations in context

Tags

RRID:IMSR_JAX:013530

RRIDCUR:Unresolved

Annotators

scibot

URL

52.53.155.43/bed7a9208c54adf86acc18c446f54a38acbd010c/1-s2.0-S2589004223010891-main-html.html
Feb 2021
www.sciencedirect.com www.sciencedirect.com

JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome

1
1. scibot 24 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX013530
  
  DOI: 10.1016/j.celrep.2020.108407
  
  Resource: (IMSR Cat# JAX_013530,RRID:IMSR_JAX:013530)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  Curator comments: B6.129S7-Dp(16Lipi-Zbtb21)1Yey/J Mus musculus IMSR Cat# JAX:013530
  
  What is this?
  
  RRIDCUR:Unresolved RRIDCUR:SyntaxError RRID:IMSR_JAX:013530
Visit annotations in context

Tags

RRIDCUR:SyntaxError

RRID:IMSR_JAX:013530

RRIDCUR:Unresolved

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720313966
Nov 2020
www.sciencedirect.com www.sciencedirect.com

JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome

1
1. scibot 25 Nov 2020
  
  in Public
  
  JAX:013530
  
  DOI: 10.1016/j.celrep.2020.108407
  
  Resource: (IMSR Cat# JAX_013530,RRID:IMSR_JAX:013530)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:013530
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:IMSR_JAX:013530

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720313966
Oct 2020
www.sciencedirect.com www.sciencedirect.com

Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome

1
1. scibot 07 Oct 2020
  
  in Public
  
  RRID:IMSR_JAX:013530
  
  DOI: 10.1016/j.neuron.2020.09.010
  
  Resource: (IMSR Cat# JAX_013530,RRID:IMSR_JAX:013530)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:013530
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:IMSR_JAX:013530

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627320307108
Nov 2017
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Trisomy 21 consistently activates the interferon response

1
1. scibot 08 Nov 2017
  
  in Public
  
  IMSR_JAX:013530
  
  Curator: @chewbeccax
  
  Resource used:
  
  RRID:IMSR_JAX:013530
  
  SciCrunch record: RRID:IMSR_JAX:013530
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:013530 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:IMSR_JAX:013530

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5012864/