45 Matching Annotations
  1. Mar 2026
  2. www.sciencedirect.com www.sciencedirect.com
    BAF60C links nucleolar stress to β cell dysfunction in type 2 diabetes through controlling Reg3b mRNA decay
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    sciencedirect.com/science/article/pii/S1534580726000717
  3. Feb 2026
  4. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    UBE2T-Driven p53 Degradation Rewires Glycolysis to Orchestrate Lactylation-Mediated CAFs Activation and ECM Deposition in Pancreatic Cancer
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202514933
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Netrin-1 Promotes Pancreatic Tumorigenesis and Innervation through NEO1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12885529/
  6. Jan 2026
  7. www.sciencedirect.com www.sciencedirect.com
    A Jagged1-regulated hybrid-EMT state identifies pancreatic cancer stem cells
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    sciencedirect.com/science/article/pii/S221112472501681X
  8. Dec 2025
  9. 54.241.53.176 54.241.53.176
    2025.12.04.691935.full-html.html
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    54.241.53.176/1e65b3fb3afccff6804d41465cf0b876d3a187ed/2025.12.04.691935.full-html.html
  10. Oct 2025
  11. www.sciencedirect.com www.sciencedirect.com
    Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas
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    sciencedirect.com/science/article/pii/S2211124725012586
  12. Aug 2025
  13. www.cell.com www.cell.com
    HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes
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    cell.com/cell-metabolism/abstract/S1550-4131(25)00334-1
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A RAS(ON) Multi-Selective Inhibitor Combination Therapy Triggers Long-term Tumor Control through Senescence-Associated Tumor-Immune Equilibrium in Pancreatic Ductal Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12319406/
  15. Jun 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FGFR2 Abrogation Intercepts Pancreatic Ductal Adenocarcinoma Development
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    pmc.ncbi.nlm.nih.gov/articles/PMC12169444/
  17. May 2025
  18. www.sciencedirect.com www.sciencedirect.com
    Regulatory network analysis of Dclk1 gene expression reveals a tuft cell-ILC2 axis that inhibits pancreatic tumor progression
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    sciencedirect.com/science/article/pii/S2211124725005054
  19. Apr 2025
  20. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/d82b50f0340a265ea39586fdf6016ce1aa48cfa1/PDF-html.html
  21. Feb 2025
  22. www.sciencedirect.com www.sciencedirect.com
    KRASG12D-driven pentose phosphate pathway remodeling imparts a targetable vulnerability synergizing with MRTX1133 for durable remissions in PDAC
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    sciencedirect.com/science/article/pii/S2666379125000394
  23. Oct 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SREBP-Dependent Regulation of Lipid Homeostasis Is Required for Progression and Growth of Pancreatic Ductal Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11444119/
  25. Jul 2024
  26. 52.53.155.43 52.53.155.43
    Cancer-associated endocrine cells participate in pancreatic carcinogenesis
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    52.53.155.43/00ed7388bef43fd34d4811e77f0e00ce1748f907/1-s2.0-S0016508524052259-main-html.html
  27. www.science.org www.science.org
    Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer
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    science.org/doi/10.1126/science.adh4567
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ehmt2 inactivation in pancreatic epithelial cells shapes the transcriptional landscape and inflammation response of the whole pancreas
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    ncbi.nlm.nih.gov/pmc/articles/PMC11211573/
  29. May 2024
  30. www.biorxiv.org www.biorxiv.org
    EHMT2 Inactivation in Pancreatic Epithelial Cells Shapes the Transcriptional Landscape and Inflammation Response of the Whole Pancreas
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    biorxiv.org/content/10.1101/2024.03.14.584700v1
  31. Feb 2024
  32. aacrjournals.org aacrjournals.org
    Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma
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    aacrjournals.org/clincancerres/article/29/24/5183/731660/Nuclear-GRP78-Promotes-Metabolic-Reprogramming-and
  33. link.springer.com link.springer.com
    Exosomes define a local and systemic communication network in healthy pancreas and pancreatic ductal adenocarcinoma
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    link.springer.com/article/10.1038/s41467-024-45753-7
  34. Jan 2024
  35. www.sciencedirect.com www.sciencedirect.com
    Spatiotemporal role of SETD2-H3K36me3 in murine pancreatic organogenesis
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    sciencedirect.com/science/article/pii/S2211124724000317
  36. www.sciencedirect.com www.sciencedirect.com
    Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
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    sciencedirect.com/science/article/pii/S1534580723003945
  37. Dec 2023
  38. 52.53.155.43 52.53.155.43
    ccr-23-1143-html.html
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    52.53.155.43/aa509a782208f9df8c6754b69c5c07021388a9c4/ccr-23-1143-html.html
  39. Aug 2023
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10463307/
  41. May 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gender-specific changes of the gut microbiome correlate with tumor development in murine models of pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10225934/
  43. www.sciencedirect.com www.sciencedirect.com
    Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress
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    sciencedirect.com/science/article/pii/S2589004223008258
  44. Nov 2022
  45. insight.jci.org insight.jci.org
    Interleukin-37 protects against acinar cell pyroptosis in acute pancreatitis
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    insight.jci.org/articles/view/161244
  46. Sep 2022
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9271144/
  48. Jun 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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    sciencedirect.com/science/article/pii/S109727652200541X
  50. Mar 2022
  51. www.sciencedirect.com www.sciencedirect.com
    Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin
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    sciencedirect.com/science/article/pii/S2211124722001681
  52. Feb 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer
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    sciencedirect.com/science/article/pii/S1535610822000058
  54. Aug 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy
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    sciencedirect.com/science/article/pii/S0092867421008795
  56. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S0012160617306875
  57. Jul 2021
  58. www.sciencedirect.com www.sciencedirect.com
    CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic β Cells
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    sciencedirect.com/science/article/pii/S2211124719310599
  59. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas
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    sciencedirect.com/science/article/pii/S1534580718309195
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inactivation of the Euchromatic Histone-Lysine N-Methyltransferase 2 Pathway in Pancreatic Epithelial Cells Antagonizes Cancer Initiation and Pancreatitis-Associated Promotion by Altering Growth and Immune Gene Expression Networks
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    ncbi.nlm.nih.gov/pmc/articles/PMC8261250/
  61. Apr 2021
  62. www.sciencedirect.com www.sciencedirect.com
    Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
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    sciencedirect.com/science/article/pii/S1535610821001185
  63. dev.biologists.org dev.biologists.org
    Groucho co-repressor proteins regulate β cell development and proliferation by repressing Foxa1 in the developing mouse pancreas
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    dev.biologists.org/content/148/6/dev192401
  64. Feb 2021
  65. www.sciencedirect.com www.sciencedirect.com
    Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas
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    sciencedirect.com/science/article/pii/S2211124721000851
  66. Sep 2020
  67. www.sciencedirect.com www.sciencedirect.com
    Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma
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    sciencedirect.com/science/article/pii/S0092867420303950
  68. www.sciencedirect.com www.sciencedirect.com
    Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer
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    sciencedirect.com/science/article/pii/S0092867420302701
  69. dev.biologists.org dev.biologists.org
    Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human β cell specification
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    dev.biologists.org/content/147/12/dev189977
  70. Jan 2020
  71. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas
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    sciencedirect.com/science/article/pii/S1534580718309195
  72. Nov 2018
  73. www.sciencedirect.com www.sciencedirect.com
    PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism
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    sciencedirect.com/science/article/pii/S1534580718305975