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  1. Last 7 days
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    A Jagged1-regulated hybrid-EMT state identifies pancreatic cancer stem cells
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    sciencedirect.com/science/article/pii/S221112472501681X
  3. Dec 2025
  4. 54.241.53.176 54.241.53.176
    2025.12.04.691935.full-html.html
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  5. Oct 2025
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    Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas
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    sciencedirect.com/science/article/pii/S2211124725012586
  7. Aug 2025
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    HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes
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    cell.com/cell-metabolism/fulltext/S1550-4131(25)00334-1
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A RAS(ON) Multi-Selective Inhibitor Combination Therapy Triggers Long-term Tumor Control through Senescence-Associated Tumor-Immune Equilibrium in Pancreatic Ductal Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12319406/
  10. Jun 2025
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    FGFR2 Abrogation Intercepts Pancreatic Ductal Adenocarcinoma Development
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    pmc.ncbi.nlm.nih.gov/articles/PMC12169444/
  12. May 2025
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    Regulatory network analysis of Dclk1 gene expression reveals a tuft cell-ILC2 axis that inhibits pancreatic tumor progression
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  14. Apr 2025
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  16. Feb 2025
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    KRASG12D-driven pentose phosphate pathway remodeling imparts a targetable vulnerability synergizing with MRTX1133 for durable remissions in PDAC
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  18. Oct 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SREBP-Dependent Regulation of Lipid Homeostasis Is Required for Progression and Growth of Pancreatic Ductal Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11444119/
  20. Jul 2024
  21. 52.53.155.43 52.53.155.43
    Cancer-associated endocrine cells participate in pancreatic carcinogenesis
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    Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer
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  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ehmt2 inactivation in pancreatic epithelial cells shapes the transcriptional landscape and inflammation response of the whole pancreas
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    ncbi.nlm.nih.gov/pmc/articles/PMC11211573/
  24. May 2024
  25. www.biorxiv.org www.biorxiv.org
    EHMT2 Inactivation in Pancreatic Epithelial Cells Shapes the Transcriptional Landscape and Inflammation Response of the Whole Pancreas
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    biorxiv.org/content/10.1101/2024.03.14.584700v1
  26. Feb 2024
  27. aacrjournals.org aacrjournals.org
    Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma
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    aacrjournals.org/clincancerres/article/29/24/5183/731660/Nuclear-GRP78-Promotes-Metabolic-Reprogramming-and
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    Exosomes define a local and systemic communication network in healthy pancreas and pancreatic ductal adenocarcinoma
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    link.springer.com/article/10.1038/s41467-024-45753-7
  29. Jan 2024
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    Spatiotemporal role of SETD2-H3K36me3 in murine pancreatic organogenesis
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    Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
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    sciencedirect.com/science/article/pii/S1534580723003945
  32. Dec 2023
  33. 52.53.155.43 52.53.155.43
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  34. Aug 2023
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10463307/
  36. May 2023
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gender-specific changes of the gut microbiome correlate with tumor development in murine models of pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10225934/
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    Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress
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    sciencedirect.com/science/article/pii/S2589004223008258
  39. Nov 2022
  40. insight.jci.org insight.jci.org
    Interleukin-37 protects against acinar cell pyroptosis in acute pancreatitis
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    insight.jci.org/articles/view/161244
  41. Sep 2022
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9271144/
  43. Jun 2022
  44. www.sciencedirect.com www.sciencedirect.com
    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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  45. Mar 2022
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    Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin
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  47. Feb 2022
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    Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer
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    sciencedirect.com/science/article/pii/S1535610822000058
  49. Aug 2021
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    Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy
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  52. Jul 2021
  53. www.sciencedirect.com www.sciencedirect.com
    CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic β Cells
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    sciencedirect.com/science/article/pii/S2211124719310599
  54. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas
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    sciencedirect.com/science/article/pii/S1534580718309195
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inactivation of the Euchromatic Histone-Lysine N-Methyltransferase 2 Pathway in Pancreatic Epithelial Cells Antagonizes Cancer Initiation and Pancreatitis-Associated Promotion by Altering Growth and Immune Gene Expression Networks
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    ncbi.nlm.nih.gov/pmc/articles/PMC8261250/
  56. Apr 2021
  57. www.sciencedirect.com www.sciencedirect.com
    Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
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    sciencedirect.com/science/article/pii/S1535610821001185
  58. dev.biologists.org dev.biologists.org
    Groucho co-repressor proteins regulate β cell development and proliferation by repressing Foxa1 in the developing mouse pancreas
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    dev.biologists.org/content/148/6/dev192401
  59. Feb 2021
  60. www.sciencedirect.com www.sciencedirect.com
    Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas
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    sciencedirect.com/science/article/pii/S2211124721000851
  61. Sep 2020
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    Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma
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    sciencedirect.com/science/article/pii/S0092867420303950
  63. www.sciencedirect.com www.sciencedirect.com
    Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer
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    sciencedirect.com/science/article/pii/S0092867420302701
  64. dev.biologists.org dev.biologists.org
    Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human β cell specification
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    dev.biologists.org/content/147/12/dev189977
  65. Jan 2020
  66. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas
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  67. Nov 2018
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    PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism
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    sciencedirect.com/science/article/pii/S1534580718305975