Hypothesis

23 Matching Annotations

Jul 2025
www.sciencedirect.com www.sciencedirect.com

Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity

1
1. scibot 23 Jul 2025
  
  in Public
  
  Jackson Laboratory Cat_016621
  
  DOI: 10.1016/j.immuni.2025.06.018
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621 RRIDCUR:Unresolved
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RRID:IMSR_JAX:016621

RRIDCUR:Unresolved

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scibot

URL

sciencedirect.com/science/article/pii/S1074761325002870
May 2025
www.sciencedirect.com www.sciencedirect.com

Inflammasome signaling in astrocytes modulates hippocampal plasticity

1
1. scibot 17 May 2025
  
  in Public
  
  RRID:IMSR_JAX:016621
  
  DOI: 10.1016/j.immuni.2025.04.007
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621
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RRID:IMSR_JAX:016621

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scibot

URL

sciencedirect.com/science/article/pii/S1074761325001700
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Plasticity of cell death pathways ensures GSDMD activation during Yersinia pseudotuberculosis infection

1
1. scibot 17 Jan 2025
  
  in Public
  
  Jackson laboratory#016621
  
  DOI: 10.1016/j.celrep.2024.115216
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621
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RRID:IMSR_JAX:016621

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724015675
Dec 2024
www.sciencedirect.com www.sciencedirect.com

A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control

1
1. scibot 02 Dec 2024
  
  in Public
  
  JAX# 016621
  
  DOI: 10.1016/j.immuni.2024.10.010
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621
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RRID:IMSR_JAX:016621

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scibot

URL

sciencedirect.com/science/article/pii/S1074761324004904
Nov 2024
www.sciencedirect.com www.sciencedirect.com

Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair

1
1. scibot 16 Nov 2024
  
  in Public
  
  RRID:IMSR_JAX:016621
  
  DOI: 10.1016/j.cell.2024.10.010
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621
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RRID:IMSR_JAX:016621

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scibot

URL

sciencedirect.com/science/article/pii/S0092867424011589
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Vaccine-elicited IL-1R signaling results in Th17 TRM-mediated immunity

1
1. scibot 21 May 2024
  
  in Public
  
  016621
  
  DOI: 10.1038/s42003-024-06138-0
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621 DOI:10.1038/s42003-024-06138-0
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DOI:10.1038/s42003-024-06138-0

RRID:IMSR_JAX:016621

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11003962/
Dec 2023
www.sciencedirect.com www.sciencedirect.com

Metabolic diversity in commensal protists regulates intestinal immunity and trans-kingdom competition

1
1. scibot 16 Dec 2023
  
  in Public
  
  Jackson LaboratoryStock#: 016621
  
  DOI: 10.1016/j.cell.2023.11.018
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621
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RRID:IMSR_JAX:016621

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scibot

URL

sciencedirect.com/science/article/pii/S0092867423012710
Jun 2023
www.biorxiv.org www.biorxiv.org

Autophagy is required to prevent early pro-inflammatory responses and neutrophil recruitment during Mycobacterium tuberculosis infection without affecting pathogen replication in macrophages

1
1. scibot 08 Jun 2023
  
  in Public
  
  Jax #016621
  
  DOI: 10.1101/2022.11.04.515221
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621
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RRID:IMSR_JAX:016621

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scibot

URL

biorxiv.org/content/10.1101/2022.11.04.515221v2
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy

1
1. scibot 03 Nov 2022
  
  in Public
  
  RRID:IMSR_JAX:016621
  
  DOI: 10.1016/j.celrep.2022.111582
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621
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RRID:IMSR_JAX:016621

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722014474
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease

1
1. scibot 02 Jun 2022
  
  in Public
  
  Jackson LaboratoryStock No: 016621
  
  DOI: 10.1016/j.neuron.2022.05.009
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621
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RRID:IMSR_JAX:016621

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627322004500
Nov 2021
www.sciencedirect.com www.sciencedirect.com

APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis

1
1. scibot 09 Nov 2021
  
  in Public
  
  Stock#16621
  
  DOI: 10.1016/j.immuni.2021.10.004
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:016621

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761321004106
Aug 2021
www.biorxiv.org www.biorxiv.org

Inflammasome-independent role for NLRP3 in controlling innate anti-helminth immunity and tissue repair in the lung

1
1. scibot 13 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:016621
  
  DOI: 10.1101/606392
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621
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RRID:IMSR_JAX:016621

Annotators

scibot

URL

biorxiv.org/content/10.1101/606392v1
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss

1
1. scibot 30 Jul 2021
  
  in Public
  
  Jackson Laboratory#016621
  
  DOI: 10.1016/j.cell.2019.12.002
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621
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RRID:IMSR_JAX:016621

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867419313285
Nov 2020
www.sciencedirect.com www.sciencedirect.com

Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity

1
1. scibot 24 Nov 2020
  
  in Public
  
  B6N.129S2-Casp1tm1Flv/J (Casp1/11 −/−)
  
  DOI: 10.1016/j.celrep.2020.108381
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  Curator comments: B6N.129S2-Casp1tm1Flv/J Mus musculus IMSR Cat# JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:016621

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472031370X
Sep 2020
link.springer.com link.springer.com

TLR2 and caspase-1 signaling are critical for bacterial containment but not clearance during craniotomy-associated biofilm infection

1
1. scibot 17 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:016621
  
  DOI: 10.1186/s12974-020-01793-6
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:016621
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Tags

RRID:IMSR_JAX:016621

RRIDCUR:Validated

Annotators

scibot

URL

link.springer.com/article/10.1186/s12974-020-01793-6
www.jimmunol.org www.jimmunol.org

Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung

1
1. scibot 10 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:016621
  
  DOI: 10.4049/jimmunol.1900640
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:016621
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Tags

RRID:IMSR_JAX:016621

RRIDCUR:Validated

Annotators

scibot

URL

jimmunol.org/content/203/10/2724
www.sciencedirect.com www.sciencedirect.com

A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling

1
1. scibot 03 Sep 2020
  
  in Public
  
  JAX stock #016621
  
  DOI: 10.1016/j.celrep.2020.03.030
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621
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RRID:IMSR_JAX:016621

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720303442
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:016621
  
  DOI: 10.1016/j.ccell.2019.04.003
  
  Resource: (IMSR Cat# JAX_016621,RRID:IMSR_JAX:016621)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  What is this?
  
  RRID:IMSR_JAX:016621 RRIDCUR:Validated
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Tags

RRID:IMSR_JAX:016621

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610819301989
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:016621
  
  Resource used:
  
  RRID:IMSR_JAX:016621
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:016621
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RRID:IMSR_JAX:016621

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761318303261
www.sciencedirect.com www.sciencedirect.com

The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced Inflammation

1
1. scibot 05 Nov 2018
  
  in Public
  
  Jax:016621
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:016621
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:016621
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RRID:IMSR_JAX:016621

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761318302036
www.sciencedirect.com www.sciencedirect.com

Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis

1
1. scibot 05 Nov 2018
  
  in Public
  
  016621
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:016621
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:016621 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:016621

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1931312818302634
www.sciencedirect.com www.sciencedirect.com

By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation

1
1. scibot 05 Nov 2018
  
  in Public
  
  016621
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:016621
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:016621 RRIDCUR:Missing
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Tags

RRIDCUR:Missing

RRID:IMSR_JAX:016621

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761317304211
www.sciencedirect.com www.sciencedirect.com

Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:016621
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:016621
  
  SciCrunch record: RRID:IMSR_JAX:016621
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:016621 RRIDCUR:Validated
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Tags

RRID:IMSR_JAX:016621

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945617304622