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  1. Last 7 days
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    PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies
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    1. scibot 17 Jul 2024
      RRID:IMSR_JAX:016959

      DOI: 10.1016/j.xcrm.2024.101649

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    sciencedirect.com/science/article/pii/S266637912400363X
  3. May 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation
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    1. scibot 21 May 2024
      016959

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    sciencedirect.com/science/article/pii/S1074761324002280
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    Adipose-tissue Treg cells restrain differentiation of stromal adipocyte precursors to promote insulin sensitivity and metabolic homeostasis
    1
    1. scibot 01 May 2024
      Jackson Laboratory016959

      DOI: 10.1016/j.immuni.2024.04.002

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    sciencedirect.com/science/article/pii/S1074761324002073
  6. Feb 2024
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    Lactate modulates RNA splicing to promote CTLA-4 expression in tumor-infiltrating regulatory T cells
    2
    1. scibot 29 Feb 2024
      RRID:IMSR_JAX:016959

      DOI: 10.1016/j.immuni.2024.01.019

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    2. scibot 29 Feb 2024
      RRID:IMSR_JAX:016959

      DOI: 10.1016/j.immuni.2024.01.019

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    sciencedirect.com/science/article/pii/S1074761324000451
  8. Dec 2023
  9. www.sciencedirect.com www.sciencedirect.com
    Oral tolerance to systemic vaccination remains intact without RORγt expression in regulatory T cells
    1
    1. scibot 21 Dec 2023
      Jackson Laboratory016959

      DOI: 10.1016/j.isci.2023.108504

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    sciencedirect.com/science/article/pii/S2589004223025816
  10. Jul 2023
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses
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    1. scibot 08 Jul 2023
      RRID:IMSR_JAX:016959

      DOI: 10.1158/2643-3230.BCD-22-0029

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    ncbi.nlm.nih.gov/pmc/articles/PMC9816815/
  12. Apr 2023
  13. www.biorxiv.org www.biorxiv.org
    Steroid Receptor Coactivator-3 is a Key Modulator of Regulatory T Cell-Mediated Tumor Evasion
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    1. scibot 20 Apr 2023
      RRID:IMSR_JAX:016959

      DOI: 10.1101/2023.03.28.534575

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    biorxiv.org/content/10.1101/2023.03.28.534575v1
  14. Jan 2023
  15. www.sciencedirect.com www.sciencedirect.com
    Opioid-induced fragile-like regulatory T cells contribute to withdrawal
    1
    1. scibot 21 Jan 2023
      RRID:IMSR_JAX:016959

      DOI: 10.1016/j.cell.2022.12.030

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    sciencedirect.com/science/article/pii/S0092867422015732
  16. Sep 2022
  17. www.sciencedirect.com www.sciencedirect.com
    Profiling of Tregs across tissues reveals plasticity in ST2 expression and hierarchies in tissue-specific phenotypes
    1
    1. scibot 15 Sep 2022
      RRID:IMSR_JAX:016959

      DOI: 10.1016/j.isci.2022.104998

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    sciencedirect.com/science/article/pii/S2589004222012706
  18. Jun 2022
  19. www.sciencedirect.com www.sciencedirect.com
    Vps33B controls Treg cell suppressive function through inhibiting lysosomal nutrient sensing complex-mediated mTORC1 activation
    1
    1. scibot 15 Jun 2022
      Jackson laboratoryStrain #:016959

      DOI: 10.1016/j.celrep.2022.110943

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    sciencedirect.com/science/article/pii/S2211124722007252
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria
    1
    1. scibot 15 Jun 2022
      RRID:IMSR_JAX:016959

      DOI: 10.7554/eLife.68598

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    ncbi.nlm.nih.gov/pmc/articles/PMC9183236/
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    Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication
    1
    1. scibot 15 Jun 2022
      JAX:016959

      DOI: 10.1016/j.immuni.2022.05.013

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    sciencedirect.com/science/article/pii/S1074761322002333
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    Intestinal inflammation alters the antigen-specific immune response to a skin commensal
    2
    1. scibot 03 Jun 2022
      Cat#016959

      DOI: 10.1016/j.celrep.2022.110891

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    2. scibot 03 Jun 2022
      Cat#016959

      DOI: 10.1016/j.celrep.2022.110891

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    sciencedirect.com/science/article/pii/S2211124722006660
  23. Apr 2022
  24. aacrjournals.org aacrjournals.org
    CDK2 Inhibition Enhances Antitumor Immunity by Increasing IFN Response to Endogenous Retroviruses
    1
    1. scibot 22 Apr 2022
      RRID:IMSR_JAX:016959

      DOI: 10.1158/2326-6066.CIR-21-0806

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    aacrjournals.org/cancerimmunolres/article/10/4/525/689540/CDK2-Inhibition-Enhances-Antitumor-Immunity-by
  25. Mar 2022
  26. www.sciencedirect.com www.sciencedirect.com
    IL-33/regulatory T cell axis suppresses skin fibrosis
    1
    1. scibot 27 Mar 2022
      RRID:IMSR_JAX

      DOI: 10.1016/j.jid.2022.03.009

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    sciencedirect.com/science/article/pii/S0022202X2200207X
  27. www.sciencedirect.com www.sciencedirect.com
    Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa
    1
    1. scibot 23 Mar 2022
      The Jackson Laboratory016959

      DOI: 10.1016/j.celrep.2022.110553

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    sciencedirect.com/science/article/pii/S2211124722002972
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The oxygen sensor prolyl hydroxylase domain 2 regulates the in vivo suppressive capacity of regulatory T cells
    1
    1. scibot 09 Mar 2022
      RRID:IMSR_JAX:016959

      DOI: 10.7554/eLife.70555

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    ncbi.nlm.nih.gov/pmc/articles/PMC8896828/
  29. Feb 2022
  30. www.sciencedirect.com www.sciencedirect.com
    Interferon-β acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation
    2
    1. scibot 11 Feb 2022
      016959

      DOI: 10.1016/j.immuni.2022.01.011

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    2. scibot 11 Feb 2022
      016959

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    sciencedirect.com/science/article/pii/S1074761322000401
  31. www.sciencedirect.com www.sciencedirect.com
    Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation
    2
    1. scibot 11 Feb 2022
      RRID:IMSR_JAX:016959

      DOI: 10.1016/j.immuni.2021.12.014

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    2. scibot 09 Feb 2022
      RRID:IMSR_JAX:016959

      DOI: 10.1016/j.immuni.2021.12.014

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    sciencedirect.com/science/article/pii/S1074761321005501
  32. Dec 2021
  33. www.sciencedirect.com www.sciencedirect.com
    AMP-activated protein kinase alpha1 promotes tumor development via FOXP3 elevation in tumor-infiltrating Treg cells
    1
    1. scibot 21 Dec 2021
      JAX:016959

      DOI: 10.1016/j.isci.2021.103570

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    sciencedirect.com/science/article/pii/S2589004221015406
  34. Nov 2021
  35. www.sciencedirect.com www.sciencedirect.com
    Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis
    1
    1. scibot 10 Nov 2021
      016959

      DOI: 10.1016/j.celrep.2021.109921

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    sciencedirect.com/science/article/pii/S2211124721013942
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function
    1
    1. scibot 05 Nov 2021
      The Jackson LaboratoryStock No: 016959

      DOI: 10.7554/eLife.67476

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    ncbi.nlm.nih.gov/pmc/articles/PMC8553335/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity
    1
    1. scibot 05 Nov 2021
      JAX:016959

      DOI: 10.3389/fimmu.2021.726393

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    ncbi.nlm.nih.gov/pmc/articles/PMC8554290/
  38. Aug 2021
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 13 Aug 2021
      JAX:016959

      DOI: 10.1016/j.celrep.2019.02.087

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    ncbi.nlm.nih.gov/pmc/articles/PMC6444001/
  40. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 02 Aug 2021
      JAX:016959

      DOI: 10.1016/j.immuni.2018.10.012

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    sciencedirect.com/science/article/pii/S1074761318304771
  41. Jul 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor
    1
    1. scibot 29 Jul 2021
      RRID: IMSR_JAX:016959

      DOI: 10.1016/j.celrep.2019.10.012

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2211124719313129
  43. www.sciencedirect.com www.sciencedirect.com
    Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells
    1
    1. scibot 28 Jul 2021
      B6.129(Cg)-Foxp3tm4(YFP/icre)Ayr/J

      DOI: 10.1016/j.celrep.2019.05.020

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    sciencedirect.com/science/article/pii/S221112471930631X
  44. www.sciencedirect.com www.sciencedirect.com
    Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation
    1
    1. scibot 23 Jul 2021
      Cat# #016959

      DOI: 10.1016/j.immuni.2021.06.014

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    sciencedirect.com/science/article/pii/S1074761321002582
  45. www.sciencedirect.com www.sciencedirect.com
    Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity
    1
    1. scibot 13 Jul 2021
      016959

      DOI: 10.1016/j.cmet.2021.06.007

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    sciencedirect.com/science/article/pii/S1550413121002771
  46. www.sciencedirect.com www.sciencedirect.com
    Splicing factor SRSF1 is indispensable for regulatory T cell homeostasis and function
    1
    1. scibot 09 Jul 2021
      stock 016959

      DOI: 10.1016/j.celrep.2021.109339

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    sciencedirect.com/science/article/pii/S2211124721007154
  47. Jun 2021
  48. www.sciencedirect.com www.sciencedirect.com
    Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop
    1
    1. scibot 22 Jun 2021
      JAX:016959

      DOI: 10.1016/j.cell.2021.05.027

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    sciencedirect.com/science/article/pii/S0092867421006577
  49. May 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Bach2 attenuates IL-2R signaling to control Treg homeostasis and Tfr development
    1
    1. scibot 12 May 2021
      RRID:IMSR_JAX:016959

      DOI: 10.1016/j.celrep.2021.109096

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    sciencedirect.com/science/article/pii/S2211124721004307
  51. www.sciencedirect.com www.sciencedirect.com
    Anti-inflammatory Roles of Glucocorticoids Are Mediated by Foxp3+ Regulatory T Cells via a miR-342-Dependent Mechanism
    1
    1. scibot 06 May 2021
      JAX:016959

      DOI: 10.1016/j.immuni.2020.07.002

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    sciencedirect.com/science/article/pii/S107476132030282X
  52. Apr 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections
    1
    1. scibot 29 Apr 2021
      Stock No: 016959

      DOI: 10.1016/j.immuni.2021.04.002

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    sciencedirect.com/science/article/pii/S1074761321001394
  54. Feb 2021
  55. elifesciences.org elifesciences.org
    Integration of IL-2 and IL-4 signals coordinates divergent regulatory T cell responses and drives therapeutic efficacy
    1
    1. scibot 26 Feb 2021
      RRID:IMSR_JAX:016959

      DOI: 10.7554/eLife.57417

      Resource: (IMSR Cat# JAX_016959,RRID:IMSR_JAX:016959)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:016959

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      RRIDCUR:Validated RRID:IMSR_JAX:016959
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    elifesciences.org/articles/57417
  56. Sep 2020
  57. www.sciencedirect.com www.sciencedirect.com
    Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function
    1
    1. scibot 03 Sep 2020
      The Jackson laboratory#016959

      DOI: 10.1016/j.cmet.2020.03.004

      Resource: (IMSR Cat# JAX_016959,RRID:IMSR_JAX:016959)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:016959
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    sciencedirect.com/science/article/pii/S1550413120301194
  58. Jan 2020
  59. www.sciencedirect.com www.sciencedirect.com
    IL-33 Signaling Alters Regulatory T Cell Diversity in Support of Tumor Development
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:016959

      DOI: 10.1016/j.celrep.2019.10.120

      Resource: (IMSR Cat# JAX_016959,RRID:IMSR_JAX:016959)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:016959 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719314536
  60. www.sciencedirect.com www.sciencedirect.com
    TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:016959

      DOI: 10.1016/j.celrep.2019.05.061

      Resource: (IMSR Cat# JAX_016959,RRID:IMSR_JAX:016959)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:016959 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719306904
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:016959

      DOI: 10.1016/j.celrep.2019.03.029

      Resource: (IMSR Cat# JAX_016959,RRID:IMSR_JAX:016959)

      Curator: @evieth

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      RRID:IMSR_JAX:016959 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6461402/
  62. Nov 2018
  63. www.sciencedirect.com www.sciencedirect.com
    CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:016959

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      RRID:IMSR_JAX:016959

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      RRID:IMSR_JAX:016959
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    sciencedirect.com/science/article/pii/S1934590918300171
  64. Nov 2017
  65. www.sciencedirect.com www.sciencedirect.com
    The Kinase mTORC1 Promotes the Generation and Suppressive Function of Follicular Regulatory T Cells
    1
    1. scibot 08 Nov 2017
      RRID:IMSR_JAX:016959

      Curator: @Jmenke

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      RRID:IMSR_JAX:016959

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      RRID:IMSR_JAX:016959 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761317303692
  66. www.sciencedirect.com www.sciencedirect.com
    Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments
    1
    1. scibot 08 Nov 2017
      016959

      Curator: @Jmenke

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      RRID:IMSR_JAX:016959

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      RRID:IMSR_JAX:016959 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1550413116306519