7 Matching Annotations
  1. Apr 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Arachidonic acid released by PIK3CA mutant tumor cells triggers malignant transformation of colonic epithelium by inducing chromatin remodeling
    1
    1. scibot 16 Apr 2024
      RRID:IMSR_JAX:016977

      DOI: 10.1016/j.xcrm.2024.101510

      Resource: (IMSR Cat# JAX_016977,RRID:IMSR_JAX:016977)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:016977

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      RRID:IMSR_JAX:016977
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    ncbi.nlm.nih.gov/pmc/articles/PMC11148513/
  3. Jun 2023
  4. aacrjournals.org aacrjournals.org
    Dysregulation of mitochondrial translation caused by CBFB deficiency cooperates with mutant PIK3CA and is a vulnerability in breast cancer
    1
    1. scibot 03 Jun 2023
      RRID:IMSR_JAX:016977

      DOI: 10.1158/0008-5472.CAN-22-2525

      Resource: (IMSR Cat# JAX_016977,RRID:IMSR_JAX:016977)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:016977

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      RRID:IMSR_JAX:016977
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    aacrjournals.org/cancerres/article/83/8/1280/725099/Dysregulation-of-Mitochondrial-Translation-Caused
  5. Nov 2022
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiple congenital malformations arise from somatic mosaicism for constitutively active Pik3ca signaling
    1
    1. scibot 10 Nov 2022
      RRID:IMSR_JAX:016

      DOI: 10.3389/fcell.2022.1013001

      Resource: (IMSR Cat# JAX_016977,RRID:IMSR_JAX:016977)

      Curator: @evieth

      SciCrunch record: RRID:IMSR_JAX:016977

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      RRID:IMSR_JAX:016977 RRIDCUR:Unresolved
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    ncbi.nlm.nih.gov/pmc/articles/PMC9637999/
  7. Aug 2022
  8. www.sciencedirect.com www.sciencedirect.com
    De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
    1
    1. scibot 22 Aug 2022
      Jackson LaboratoriesCat# 016977

      DOI: 10.1016/j.ccell.2022.07.011

      Resource: (IMSR Cat# JAX_016977,RRID:IMSR_JAX:016977)

      Curator: @sophiastull

      SciCrunch record: RRID:IMSR_JAX:016977

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      RRID:IMSR_JAX:016977
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    sciencedirect.com/science/article/pii/S1535610822003245
  9. Jul 2021
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Somatic mutations activating the mTOR pathway in dorsal telencephalic progenitors cause a continuum of cortical dysplasias
    1
    1. scibot 27 Jul 2021
      RRID:MGI_5000472

      DOI: 10.1016/j.celrep.2017.11.106

      Resource: (IMSR Cat# JAX_016977,RRID:IMSR_JAX:016977)

      Curator: @evieth

      SciCrunch record: RRID:IMSR_JAX:016977

      Curator comments: IMSR Cat# JAX:016977, FVB.129S6-Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/J Mus musculus

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      RRID:IMSR_JAX:016977 RRIDCUR:Unresolved RRIDCUR:Incorrect
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    ncbi.nlm.nih.gov/pmc/articles/PMC5752134/
  11. Nov 2020
  12. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation
    1
    1. scibot 14 Nov 2020
      (Gt)Rosa26Pik3ca∗H1047R

      DOI: 10.1016/j.celrep.2020.108366

      Resource: (IMSR Cat# JAX_016977,RRID:IMSR_JAX:016977)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:016977

      Curator comments: FVB.129S6-Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/J Mus musculus IMSR Cat# JAX:016977

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      RRID:IMSR_JAX:016977 RRIDCUR:Missing
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    pubmed.ncbi.nlm.nih.gov/33176148/
  13. Sep 2020
  14. www.sciencedirect.com www.sciencedirect.com
    Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas
    1
    1. scibot 09 Sep 2020
      RRID:IMSR_JAX:016977

      DOI: 10.1016/j.ccell.2020.02.002

      Resource: (IMSR Cat# JAX_016977,RRID:IMSR_JAX:016977)

      Curator: @ethanbadger

      SciCrunch record: RRID:IMSR_JAX:016977

      What is this?
      RRID:IMSR_JAX:016977 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S153561082030091X