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39 Matching Annotations

Last 7 days
www.nature.com www.nature.com

Slc7a5 promotes T cell anti-tumor immunity through sustaining cytotoxic T lymphocyte effector function

1
1. scibot 04 Sep 2025
  
  in Public
  
  stock # 017336
  
  DOI: 10.1038/s41388-025-03543-5
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

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nature.com/articles/s41388-025-03543-5
Jun 2025
www.biorxiv.org www.biorxiv.org

Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment

1
1. scibot 25 Jun 2025
  
  in Public
  
  IMSR_JAX:017336
  
  DOI: 10.1101/2023.03.13.532431
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @sonofthor
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

biorxiv.org/content/10.1101/2023.03.13.532431v1
May 2025
www.sciencedirect.com www.sciencedirect.com

B cell-derived acetylcholine promotes liver regeneration by regulating Kupffer cell and hepatic CD8+ T cell function

1
1. scibot 16 May 2025
  
  in Public
  
  The Jackson LabratoryStrain #017336
  
  DOI: 10.1016/j.immuni.2025.04.002
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S1074761325001657
Apr 2025
www.sciencedirect.com www.sciencedirect.com

Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells

1
1. scibot 03 Apr 2025
  
  in Public
  
  JAX:017336
  
  DOI: 10.1016/j.celrep.2025.115510
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

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sciencedirect.com/science/article/pii/S2211124725002815
Feb 2025
www.nature.com www.nature.com

STIM1-mediated NFAT signaling synergizes with STAT1 to control T-bet expression and TH1 differentiation

1
1. scibot 25 Feb 2025
  
  in Public
  
  JAX strain 017336
  
  DOI: 10.1038/s41590-025-02089-8
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

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nature.com/articles/s41590-025-02089-8
Dec 2024
www.biorxiv.org www.biorxiv.org

Glutaminolysis promotes the function of follicular helper T cells in lupus-prone mice

1
1. scibot 06 Dec 2024
  
  in Public
  
  JAX:017336
  
  DOI: 10.1101/2024.11.25.625088
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

biorxiv.org/content/10.1101/2024.11.25.625088v1
Sep 2024
www.sciencedirect.com www.sciencedirect.com

CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

1
1. scibot 18 Sep 2024
  
  in Public
  
  Stock# 017336
  
  DOI: 10.1016/j.cmet.2017.10.006
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S1550413117306186
May 2024
www.sciencedirect.com www.sciencedirect.com

Antigen-level resolution of commensal-specific B cell responses can be enabled by phage display screening coupled with B cell tetramers

1
1. scibot 09 May 2024
  
  in Public
  
  RRID:IMSR_JAX:017336
  
  DOI: 10.1016/j.immuni.2024.04.014
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S107476132400219X
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Amphiregulin from regulatory T cells promotes liver fibrosis and insulin resistance in non-alcoholic steatohepatitis

2
1. scibot 06 Feb 2024
  
  in Public
  
  JAX:017336
  
  DOI: 10.1016/j.immuni.2024.01.009
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
  What is this?
  
  RRID:IMSR_JAX:017336
2. scibot 06 Feb 2024
  
  in Public
  
  JAX:017336
  
  DOI: 10.1016/j.immuni.2024.01.009
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S1074761324000347
Jan 2024
www.nature.com www.nature.com

Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment

1
1. scibot 14 Jan 2024
  
  in Public
  
  RRID:IMSR_JAX:017336
  
  DOI: 10.1038/s41467-024-44689-2
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

nature.com/articles/s41467-024-44689-2
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease

1
1. scibot 13 Oct 2023
  
  in Public
  
  RRID:IMSR_JAX:017336
  
  DOI: 10.1016/j.xcrm.2023.101236
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S2666379123004135
Mar 2023
www.sciencedirect.com www.sciencedirect.com

Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut

1
1. scibot 16 Mar 2023
  
  in Public
  
  JAX:017
  
  DOI: 10.1016/j.immuni.2023.02.018
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @sofiakhan13
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_JAX:017336
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RRIDCUR:Unresolved

RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S1074761323000924
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A selective LIS1 requirement for mitotic spindle assembly discriminates distinct T-cell division mechanisms within the T-cell lineage

1
1. scibot 30 Dec 2022
  
  in Public
  
  RRID:IMSR_JAX:017336
  
  DOI: 10.7554/eLife.80277
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9797186/
Oct 2022
www.sciencedirect.com www.sciencedirect.com

Transcription factor RORα enforces stability of the Th17 cell effector program by binding to a Rorc cis-regulatory element

1
1. scibot 18 Oct 2022
  
  in Public
  
  JAX:017336
  
  DOI: 10.1016/j.immuni.2022.09.013
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S1074761322005076
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cbl-b Restrains Priming of Pathogenic Th17 Cells via the Inhibition of IL-6 Production by Macrophages

1
1. scibot 04 Oct 2022
  
  in Public
  
  RRID:IMSR_JAX:017336
  
  DOI: 10.1016/j.isci.2022.105151
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9523381/
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Intestinal inflammation alters the antigen-specific immune response to a skin commensal

1
1. scibot 03 Jun 2022
  
  in Public
  
  Cat#017336
  
  DOI: 10.1016/j.celrep.2022.110891
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722006660
May 2022
www.sciencedirect.com www.sciencedirect.com

STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program

1
1. scibot 26 May 2022
  
  in Public
  
  The Jackson LaboratoryStock No: 017336
  
  DOI: 10.1016/j.celrep.2022.110838
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
  What is this?
  
  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722006118
Apr 2022
www.sciencedirect.com www.sciencedirect.com

Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma

1
1. scibot 20 Apr 2022
  
  in Public
  
  Jackson LabsStock No: 017,336
  
  DOI: 10.1016/j.celrep.2022.110695
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722004533
Dec 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation

1
1. scibot 08 Dec 2021
  
  in Public
  
  RRID:IMSR_JAX:017336
  
  DOI: 10.7554/eLife.70978
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8639145/
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 02 Aug 2021
  
  in Public
  
  JAX:017336
  
  DOI: 10.1016/j.immuni.2018.10.012
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S1074761318304771
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R−STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:017336
  
  DOI: 10.1016/j.immuni.2018.10.010
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:017336
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RRIDCUR:Validated

RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S1074761318304758
www.sciencedirect.com www.sciencedirect.com

Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity

1
1. scibot 29 Jul 2021
  
  in Public
  
  Jackson LaboratoryStock#017336
  
  DOI: 10.1016/j.celrep.2019.07.065
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
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  RRID:IMSR_JAX:017336 RRIDCUR:Unrecognized
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RRIDCUR:Unrecognized

RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719309696
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality

1
1. scibot 29 Jul 2021
  
  in Public
  
  The Jackson LaboratoryCat# 017336
  
  DOI: 10.1016/j.immuni.2019.08.013
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
  What is this?
  
  RRID:IMSR_JAX:017336 RRIDCUR:Unrecognized
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RRIDCUR:Unrecognized

RRID:IMSR_JAX:017336

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC6903704/
www.sciencedirect.com www.sciencedirect.com

Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells

1
1. scibot 28 Jul 2021
  
  in Public
  
  STOCK Tg(CD4-cre)1Cwi/BfluJ
  
  DOI: 10.1016/j.celrep.2019.05.020
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
  What is this?
  
  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S221112471930631X
www.sciencedirect.com www.sciencedirect.com

Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness

1
1. scibot 28 Jul 2021
  
  in Public
  
  Mouse: Tg(Cd4-cre)1Cwi/BfluJ
  
  DOI: 10.1016/j.immuni.2019.03.005
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:017336
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RRIDCUR:Missing

RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S1074761319300950
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells

1
1. scibot 30 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:017336
  
  DOI: 10.1016/j.cmet.2020.10.022
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
  What is this?
  
  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S155041312030591X
www.sciencedirect.com www.sciencedirect.com

MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23

1
1. scibot 26 Apr 2021
  
  in Public
  
  The Jackson Laboratory# 017336
  
  DOI: 10.1016/j.immuni.2021.02.015
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
  What is this?
  
  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S1074761321000819
www.sciencedirect.com www.sciencedirect.com

In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions

1
1. scibot 11 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:017336
  
  DOI: 10.1016/j.cell.2021.02.021
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
  What is this?
  
  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S0092867421001719
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy

1
1. scibot 26 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:017336
  
  DOI: 10.1016/j.immuni.2020.04.007
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
  What is this?
  
  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7784612/
Sep 2020
www.sciencedirect.com www.sciencedirect.com

T Cell Factor 1 Suppresses CD103+ Lung Tissue-Resident Memory T Cell Development

1
1. scibot 03 Sep 2020
  
  in Public
  
  JAX Strain# 017336
  
  DOI: 10.1016/j.celrep.2020.03.048
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
  What is this?
  
  RRID:IMSR_JAX:017336
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RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S2211124720303624
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:017336
  
  DOI: 10.1016/j.celrep.2019.10.087
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
  What is this?
  
  RRID:IMSR_JAX:017336 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719314093
www.sciencedirect.com www.sciencedirect.com

Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:017336
  
  DOI: 10.1016/j.immuni.2019.10.001
  
  Resource: (IMSR Cat# JAX_017336,RRID:IMSR_JAX:017336)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:017336
  
  What is this?
  
  RRID:IMSR_JAX:017336 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:017336

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scibot

URL

sciencedirect.com/science/article/pii/S1074761319304182
elifesciences.org elifesciences.org

The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets

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  DOI: 10.7554/eLife.44245
  
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Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R−STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity

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  DOI: 10.1016/j.immuni.2018.10.010
  
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  Curator: @Jmenke
  
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.cmet.2019.01.019
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1550413119300191
Nov 2018
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LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection

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Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors

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1. scibot 05 Nov 2018
  
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Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR

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1. scibot 05 Nov 2018
  
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