Hypothesis

33 Matching Annotations

Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeted Delivery of a Potent STING Agonist Payload via an Antibody–Drug Conjugate Drives Robust Antitumor Activity in Preclinical Models

1
1. scibot 12 Apr 2026
  
  in Public
  
  JAX:017537
  
  DOI: 10.1158/1535-7163.MCT-25-0108
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
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  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC13060629/
Mar 2026
www.sciencedirect.com www.sciencedirect.com

Radiotherapy synergizes with an inducible AAV-based immunotherapy platform to program local and systemic antitumor immunity

1
1. scibot 24 Mar 2026
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1016/j.ccell.2026.02.013
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
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  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S153561082600111X
Feb 2026
www.sciencedirect.com www.sciencedirect.com

Cytosolic DNA structures produced by mismatch repair deficiency coordinate anti-tumor immunity in colorectal cancer

1
1. scibot 20 Feb 2026
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1016/j.celrep.2026.117012
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
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  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S2211124726000902
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

1
1. scibot 17 Dec 2025
  
  in Public
  
  The Jackson Laboratory Cat_017537
  
  DOI: 10.1016/j.cell.2025.11.023
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

RRIDCUR:Unresolved

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scibot

URL

sciencedirect.com:5037/science/article/pii/S0092867425013583
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The microbial metabolite desaminotyrosine protects against graft-versus-host disease via mTORC1 and STING-dependent intestinal regeneration

1
1. scibot 23 Oct 2025
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1038/s41467-025-65180-6
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
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  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12537870/
Jun 2025
www.sciencedirect.com www.sciencedirect.com

ILC3s sense gut microbiota through STING to initiate immune tolerance

1
1. scibot 17 Jun 2025
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1016/j.immuni.2025.05.016
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
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  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S1074761325002377
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

cGAS and STING in Host Myeloid Cells Are Essential for Effective Cyclophosphamide Treatment of Advanced Breast Cancer

1
1. scibot 19 Apr 2025
  
  in Public
  
  JAX:017537
  
  DOI: 10.3390/cancers17071130
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
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  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11987962/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

VAX014 Activates Tumor-Intrinsic STING and RIG-I to Promote the Development of Antitumor Immunity

1
1. scibot 04 Apr 2025
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1158/1535-7163.MCT-24-0509
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
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  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11962400/
www.sciencedirect.com www.sciencedirect.com

Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells

1
1. scibot 03 Apr 2025
  
  in Public
  
  JAX:017537
  
  DOI: 10.1016/j.celrep.2025.115510
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
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  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S2211124725002815
Feb 2025
www.sciencedirect.com www.sciencedirect.com

ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation

1
1. scibot 13 Feb 2025
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1016/j.cell.2025.01.027
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S0092867425000960
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia

1
1. scibot 17 Dec 2024
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1016/j.neuron.2016.12.021
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
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  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC5600182/
www.sciencedirect.com www.sciencedirect.com

1-s2.0-S2589004224027718-main-html.html

1
1. scibot 10 Dec 2024
  
  in Public
  
  RRID:IMSR_JAX:0
  
  DOI: 10.1016/j.isci.2024.111544
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRID:IMSR_JAX:017537 RRIDCUR:Unresolved
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RRIDCUR:Unresolved

RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S2589004224027718
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity

1
1. scibot 04 Jun 2024
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1016/j.celrep.2024.114289
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
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  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11315447/
Feb 2024
www.sciencedirect.com www.sciencedirect.com

STING deficiency alleviates ferroptosis through FPN1 stabilization in diabetic kidney disease

2
1. scibot 29 Feb 2024
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1016/j.bcp.2024.116102
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRID:IMSR_JAX:017537
2. scibot 29 Feb 2024
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1016/j.bcp.2024.116102
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S0006295224000856
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Vinorelbine causes a neuropathic pain-like state in mice via STING and MNK1 signaling associated with type I interferon induction.

1
1. scibot 19 Jan 2024
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1016/j.isci.2024.108808
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S2589004224000294
www.sciencedirect.com www.sciencedirect.com

Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity

1
1. scibot 04 Jan 2024
  
  in Public
  
  017537
  
  DOI: 10.1016/j.cell.2023.05.039
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S0092867423005913
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells

1
1. scibot 14 Oct 2023
  
  in Public
  
  JAX:017537
  
  DOI: 10.1016/j.celrep.2023.113180
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S2211124723011920
Mar 2023
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

STING agonist-loaded, CD47/PD-L1-targeting nanoparticles potentiate antitumor immunity and radiotherapy for glioblastoma

1
1. scibot 28 Mar 2023
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1038/s41467-023-37328-9
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

pubmed.ncbi.nlm.nih.gov/36959214/
www.sciencedirect.com www.sciencedirect.com

Protocol for the identification and expression analysis of a cytoplasmic membrane-localized protein STING

1
1. scibot 23 Mar 2023
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1016/j.xpro.2023.102172
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S2666166723001302
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy

1
1. scibot 03 Nov 2022
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1016/j.celrep.2022.111582
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722014474
May 2022
www.sciencedirect.com www.sciencedirect.com

STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program

1
1. scibot 26 May 2022
  
  in Public
  
  The Jackson LaboratoryStock No: 017537
  
  DOI: 10.1016/j.celrep.2022.110838
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722006118
www.sciencedirect.com www.sciencedirect.com

The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis

1
1. scibot 11 May 2022
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1016/j.immuni.2022.04.006
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S1074761322001777
Dec 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia

1
1. scibot 11 Dec 2021
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1016/j.isci.2021.103434
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8633968/
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 09 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1016/j.celrep.2018.11.047
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
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  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S2211124718318102
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 31 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.1016/j.neuron.2016.12.021
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5600182/
Jan 2021
www.sciencedirect.com www.sciencedirect.com

Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma

1
1. scibot 21 Jan 2021
  
  in Public
  
  Stock # 017537
  
  DOI: 10.1016/j.celrep.2020.108620
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRID:IMSR_JAX:017537 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S2211124720316090
Sep 2020
elifesciences.org elifesciences.org

Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING

1
1. scibot 25 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  DOI: 10.7554/eLife.56882
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:017537
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RRIDCUR:Validated

RRID:IMSR_JAX:017537

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scibot

URL

elifesciences.org/articles/56882
www.sciencedirect.com www.sciencedirect.com

Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity

1
1. scibot 03 Sep 2020
  
  in Public
  
  Jackson LaboratoryStock# 017537
  
  DOI: 10.1016/j.immuni.2020.03.016
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
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  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S1074761320301291
www.sciencedirect.com www.sciencedirect.com

SPHK2-Generated S1P in CD11b+ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages

1
1. scibot 03 Sep 2020
  
  in Public
  
  Jackson Laboratory# 017537
  
  DOI: 10.1016/j.celrep.2020.02.112
  
  Resource: (IMSR Cat# JAX_017537,RRID:IMSR_JAX:017537)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
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  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S221112472030293X
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response

1
1. scibot 05 Nov 2018
  
  in Public
  
  017537
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:017537
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:017537 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S107476131830431X
www.sciencedirect.com www.sciencedirect.com

Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:017537
  
  Resource used:
  
  RRID:IMSR_JAX:017537
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:017537
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RRID:IMSR_JAX:017537

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scibot

URL

sciencedirect.com/science/article/pii/S0896627317310851
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia

1
1. scibot 08 Nov 2017
  
  in Public
  
  IMSR_JAX:017537
  
  Curator: @gabimpine
  
  Resource used:
  
  RRID:IMSR_JAX:017537
  
  SciCrunch record: RRID:IMSR_JAX:017537
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:017537 RRIDCUR:Validated
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Tags

RRIDCUR:Validated

RRID:IMSR_JAX:017537

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627316309941