Hypothesis

37 Matching Annotations

Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Microglia Display Heterogeneous Initial Responses to Disseminated Tumor Cells

1
1. scibot 26 Mar 2026
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  DOI: 10.1158/0008-5472.CAN-25-3425
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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pmc.ncbi.nlm.nih.gov/articles/PMC13012254/
www.sciencedirect.com www.sciencedirect.com

6-Hydroxydopamine promotes antitumor immunity through macrophage remodeling beyond sympathetic ablation

1
1. scibot 20 Mar 2026
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  DOI: 10.1016/j.neuron.2026.02.028
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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sciencedirect.com/science/article/pii/S0896627326001339
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Microglia and myeloid cell populations of the developing mouse retina

1
1. scibot 04 Feb 2026
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  DOI: 10.1002/glia.70115
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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pmc.ncbi.nlm.nih.gov/articles/PMC12857260/
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

In toto imaging shows intravascular proliferation promotes transmigration of daughter cells during brain invasion of Cryptococcus neoformans

1
1. scibot 09 Dec 2025
  
  in Public
  
  The Jackson LaboratoryStrain #017586
  
  DOI: 10.1016/j.celrep.2025.116658
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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sciencedirect.com:5037/science/article/pii/S2211124725014305
Oct 2025
www.biorxiv.org www.biorxiv.org

Fluid-Niche and Microglial Signatures Prime Robust Intraventricular Macrophage Response to Blood During Brain Development

1
1. scibot 07 Oct 2025
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  DOI: 10.1101/2025.10.02.679906
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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biorxiv.org/content/10.1101/2025.10.02.679906v1
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Gut microbe-derived metabolites drive psoriatic inflammation via modulation of skin Th17 cells

1
1. scibot 11 Sep 2025
  
  in Public
  
  JAX:017586
  
  DOI: 10.1016/j.immuni.2025.08.006
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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sciencedirect.com/science/article/pii/S1074761325003693
Apr 2025
www.sciencedirect.com www.sciencedirect.com

A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection

1
1. scibot 24 Apr 2025
  
  in Public
  
  The Jackson LaboratoriesCat#017586
  
  DOI: 10.1016/j.cell.2025.03.043
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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sciencedirect.com/science/article/pii/S0092867425003952
Mar 2025
www.cell.com www.cell.com

Temporal dynamics of immune cell transcriptomics in brain metastasis progression influenced by gut microbiome dysbiosis

1
1. scibot 05 Mar 2025
  
  in Public
  
  Stock#:017586
  
  DOI: 10.1016/j.celrep.2025.115356
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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URL

cell.com/cell-reports/abstract/S2211-1247(25)00127-5
Feb 2025
www.sciencedirect.com www.sciencedirect.com

Macrophage-derived CTSS drives the age-dependent disruption of the blood-CSF barrier

1
1. scibot 27 Feb 2025
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  DOI: 10.1016/j.neuron.2025.01.023
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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sciencedirect.com/science/article/pii/S0896627325000492
www.sciencedirect.com www.sciencedirect.com

A bladder-blood immune barrier constituted by suburothelial perivascular macrophages restrains uropathogen dissemination

1
1. scibot 27 Feb 2025
  
  in Public
  
  JAX:017586
  
  DOI: 10.1016/j.immuni.2025.02.002
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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sciencedirect.com/science/article/pii/S107476132500069X
Jan 2025
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 08 Jan 2025
  
  in Public
  
  017586
  
  DOI: 10.1242/dmm.052012
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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52.53.155.43/655757fa415bf079eca462bbd3dfdcf1acc316d2/PDF-html.html
Aug 2024
www.sciencedirect.com www.sciencedirect.com

The choroid plexus synergizes with immune cells during neuroinflammation

1
1. scibot 01 Aug 2024
  
  in Public
  
  017586
  
  DOI: 10.1016/j.cell.2024.07.002
  
  Resource: IMSR_JAX:017586
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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sciencedirect.com/science/article/pii/S0092867424007177
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Dynamic landscapes and protective immunity coordinated by influenza-specific lung-resident memory CD8+ T cells revealed by intravital imaging

1
1. scibot 25 Jul 2024
  
  in Public
  
  Jackson Laboratory Cat_017586
  
  DOI: 10.1016/j.immuni.2024.06.016
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586 RRIDCUR:Unresolved
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RRID:IMSR_JAX:017586

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scibot

URL

sciencedirect.com/science/article/pii/S1074761324003224
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting transitioning lung monocytes/macrophages as treatment strategies in lung disease related to environmental exposures

1
1. scibot 11 Apr 2024
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  DOI: 10.1186/s12931-024-02804-3
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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ncbi.nlm.nih.gov/pmc/articles/PMC11003126/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RBP-J regulates homeostasis and function of circulating Ly6Clo monocytes

1
1. scibot 19 Mar 2024
  
  in Public
  
  Strain #: 017586 from Jackson Laboratory
  
  DOI: 10.7554/eLife.88135
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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ncbi.nlm.nih.gov/pmc/articles/PMC10942619/
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Modulation of central synapse remodeling after remote peripheral injuries by the CCL2-CCR2 axis and microglia

1
1. scibot 22 Feb 2024
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  DOI: 10.1016/j.celrep.2024.113776
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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sciencedirect.com/science/article/pii/S2211124724001049
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Bacterial infection disrupts established germinal center reactions through monocyte recruitment and impaired metabolic adaptation

1
1. scibot 23 Feb 2022
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  DOI: 10.1016/j.immuni.2022.01.013
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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sciencedirect.com/science/article/pii/S1074761322000425
Aug 2021
link.springer.com link.springer.com

Untitled document

1
1. scibot 07 Aug 2021
  
  in Public
  
  JAX:017586
  
  DOI: 10.1007/s13238-018-0599-3
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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link.springer.com/article/10.1007/s13238-018-0599-3
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Transcriptional mechanism of IRF8 and PU.1 governs microglial activation in neurodegenerative condition

1
1. scibot 31 Jul 2021
  
  in Public
  
  JAX:017586
  
  DOI: 10.1007/s13238-018-0599-3
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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ncbi.nlm.nih.gov/pmc/articles/PMC6340890/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull-meninges connections

1
1. scibot 29 Jul 2021
  
  in Public
  
  017586
  
  DOI: 10.1038/s41593-018-0301-3
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRIDCUR:Missing RRID:IMSR_JAX:017586
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RRIDCUR:Missing

RRID:IMSR_JAX:017586

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6494982/
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 29 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  DOI: 10.1016/j.mbplus.2019.03.002
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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sciencedirect.com/science/article/pii/S259002851930002X
gut.bmj.com gut.bmj.com

Myeloid cells in liver and bone marrow acquire a functionally distinct inflammatory phenotype during obesity-related steatohepatitis

1
1. scibot 28 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  DOI: 10.1136/gutjnl-2019-318382
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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gut.bmj.com/content/early/2019/05/10/gutjnl-2019-318382
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity

1
1. scibot 27 Jul 2021
  
  in Public
  
  JAX:017586
  
  DOI: 10.1016/j.cmet.2018.12.003
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6701710/
Apr 2021
www.sciencedirect.com www.sciencedirect.com

CNS-Native Myeloid Cells Drive Immune Suppression in the Brain Metastatic Niche through Cxcl10

1
1. scibot 24 Apr 2021
  
  in Public
  
  017586
  
  DOI: 10.1016/j.cell.2020.09.064
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586 RRIDCUR:Missing
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RRID:IMSR_JAX:017586

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scibot

URL

sciencedirect.com/science/article/pii/S0092867420313052
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CCL2/MCP-1 signaling drives extracellular matrix turnover by diverse macrophage subsets

1
1. scibot 09 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  DOI: 10.1016/j.mbplus.2019.03.002
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586 RRIDCUR:Validated
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RRID:IMSR_JAX:017586

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7852312/
Jan 2021
www.sciencedirect.com www.sciencedirect.com

Airway-Associated Macrophages in Homeostasis and Repair

1
1. scibot 05 Jan 2021
  
  in Public
  
  Ccr2tm2.1Ifc/J
  
  DOI: 10.1016/j.celrep.2020.108553
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586 RRIDCUR:Missing
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RRID:IMSR_JAX:017586

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sciencedirect.com/science/article/pii/S2211124720315424
Dec 2020
www.cell.com www.cell.com

Inflammation of the Embryonic Choroid Plexus Barrier following Maternal Immune Activation

1
1. scibot 11 Dec 2020
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  DOI: 10.1016/j.devcel.2020.09.020
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586 RRIDCUR:Validated
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RRID:IMSR_JAX:017586

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URL

cell.com/developmental-cell/abstract/S1534-5807(20)30722-X
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction

1
1. scibot 23 Sep 2020
  
  in Public
  
  Ccr2RFP
  
  DOI: 10.15252/embj.2020104464
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
  Curator comments: B6.129(Cg)-Ccr2tm2.1Ifc/J Mus musculus IMSR Cat# JAX:017586
  
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  RRIDCUR:Missing RRID:IMSR_JAX:017586
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RRID:IMSR_JAX:017586

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scibot

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pubmed.ncbi.nlm.nih.gov/32959911/
www.sciencedirect.com www.sciencedirect.com

Fractalkine-Dependent Microglial Pruning of Viable Oligodendrocyte Progenitor Cells Regulates Myelination

1
1. scibot 23 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  DOI: 10.1016/j.celrep.2020.108047
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRIDCUR:Validated RRID:IMSR_JAX:017586
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RRID:IMSR_JAX:017586

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URL

sciencedirect.com/science/article/pii/S2211124720310329
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Astrocyte- and Neuron-Derived CXCL1 Drives Neutrophil Transmigration and Blood-Brain Barrier Permeability in Viral Encephalitis

1
1. scibot 16 Sep 2020
  
  in Public
  
  C57BL/6-CCR2-/-
  
  DOI: 10.1016/j.celrep.2020.108150
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
  Curator comments: B6.129(Cg)-Ccr2tm2.1Ifc/J Mus musculus IMSR Cat# JAX:017586
  
  What is this?
  
  RRID:IMSR_JAX:017586 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:017586

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scibot

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pubmed.ncbi.nlm.nih.gov/32937134/
www.nature.com www.nature.com

Microglia Dynamics and Interactions with Motoneurons Axotomized After Nerve Injuries Revealed By Two-Photon Imaging

1
1. scibot 16 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  DOI: 10.1038/s41598-020-65363-9
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRIDCUR:Validated RRID:IMSR_JAX:017586
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RRIDCUR:Validated

RRID:IMSR_JAX:017586

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scibot

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nature.com/articles/s41598-020-65363-9
www.sciencedirect.com www.sciencedirect.com

Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization

1
1. scibot 03 Sep 2020
  
  in Public
  
  The Jackson LaboratoryCat# 017586
  
  DOI: 10.1016/j.celrep.2020.107679
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586
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RRID:IMSR_JAX:017586

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scibot

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sciencedirect.com/science/article/pii/S221112472030632X
Jan 2020
www.jneurosci.org www.jneurosci.org

Spinal Motor Circuit Synaptic Plasticity after Peripheral Nerve Injury Depends on Microglia Activation and a CCR2 Mechanism

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  DOI: 10.1523/JNEUROSCI.2945-17.2019
  
  Resource: (IMSR Cat# JAX_017586,RRID:IMSR_JAX:017586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586 RRIDCUR:Validated
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jneurosci.org/content/39/18/3412
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis

1
1. scibot 05 Nov 2018
  
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  017586
  
  Curator: @Jmenke
  
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  SciCrunch record: RRID:IMSR_JAX:017586
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:017586 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S0092867418309760
Nov 2017
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A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:IMSR_JAX:017586
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:017586
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1074761317303254
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Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy

1
1. scibot 08 Nov 2017
  
  in Public
  
  Mouse: Ccr2RFP/+: B6.129(Cg)-Ccr2tm2.1Ifc/JJackson LaboratoriesStock No. 017586
  
  Curator: @Jmenke
  
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  RRID:IMSR_JAX:017586
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
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  RRID:IMSR_JAX:017586 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1934590917300954
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Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility

1
1. scibot 08 Nov 2017
  
  in Public
  
  Mouse: B6.129(Cg)-Ccr2tm2.1Ifc/JThe Jackson LaboratoryJAX: 017586
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:017586
  
  SciCrunch record: RRID:IMSR_JAX:017586
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:017586 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S155041311730339X