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Microbiome-produced nicotinic acid controls colon regional identity and injury susceptibility

1
1. scibot 17 Mar 2026
  
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  JAX:020282
  
  DOI: 10.1016/j.cell.2026.02.007
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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scibot

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sciencedirect.com/science/article/pii/S0092867426001728
Mar 2026
www.sciencedirect.com www.sciencedirect.com

APC coordinates GSK3 phosphorylation of SETD8 to suppress colorectal cancer

1
1. scibot 06 Mar 2026
  
  in Public
  
  The Jackson LaboratoryJAX 020282
  
  DOI: 10.1016/j.celrep.2026.117045
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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scibot

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sciencedirect.com/science/article/pii/S2211124726001233
Jan 2026
www.biorxiv.org www.biorxiv.org

Genotype-phenotype mapping identifies fetal-like CD55+ immunoregulatory cancer cells as mediators of immune escape in colorectal cancer

1
1. scibot 13 Jan 2026
  
  in Public
  
  RRID:IMSR_JAX:020282
  
  DOI: 10.64898/2026.01.09.697991
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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scibot

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biorxiv.org/content/10.64898/2026.01.09.697991v1
Nov 2025
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Fosl1 is a transcriptional effector of BRAFV600E-driven intestinal tumorigenesis

1
1. scibot 15 Nov 2025
  
  in Public
  
  Jackson Stock Number: 020282
  
  DOI: 10.1016/j.isci.2025.113875
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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sciencedirect.com/science/article/pii/S2589004225021364
54.241.53.176 54.241.53.176

2025.11.06.687030v2.full-html.html

1
1. scibot 13 Nov 2025
  
  in Public
  
  RRID:IMSR_JAX:020282
  
  DOI: 10.1101/2025.11.06.687030
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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54.241.53.176/61ff3c01c4fabc7d4036cd8525cf0aefcb431dbf/2025.11.06.687030v2.full-html.html
Oct 2025
www.science.org www.science.org

T cell cholesterol transport links intestinal immune responses to dietary lipid absorption

1
1. scibot 23 Oct 2025
  
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  RRID:IMSR_JAX:020282
  
  DOI: 10.1126/science.adt4169
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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science.org/doi/10.1126/science.adt4169
Jul 2025
www.sciencedirect.com www.sciencedirect.com

MLKL activates the cGAS-STING pathway by releasing mitochondrial DNA upon necroptosis induction

1
1. scibot 03 Jul 2025
  
  in Public
  
  RRID:IMSR_JAX:020282
  
  DOI: 10.1016/j.molcel.2025.06.005
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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sciencedirect.com/science/article/pii/S1097276525005052
May 2025
52.53.155.43 52.53.155.43

CapdevilaCastillo_columbia_0054D_18600-html.html

1
1. scibot 22 May 2025
  
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  JAX:020282
  
  DOI: 10.7916/kcm5-sk40
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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52.53.155.43/defa13d4e31bf105e951133a04f91af42d68a175/CapdevilaCastillo_columbia_0054D_18600-html.html
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Vagal pathway activation links chronic stress to decline in intestinal stem cell function

1
1. scibot 24 Mar 2025
  
  in Public
  
  The Jackson Laboratory Stock_020282
  
  DOI: 10.1016/j.stem.2025.02.016
  
  Resource: None
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282 RRIDCUR:Unresolved
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RRIDCUR:Unresolved

RRID:IMSR_JAX:020282

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scibot

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sciencedirect.com/science/article/pii/S1934590925000840
Feb 2025
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Nudix Hydrolase 13 Impairs the Initiation of Colorectal Cancer by Inhibiting PKM1 ADP-Ribosylation

1
1. scibot 11 Feb 2025
  
  in Public
  
  RRID:IMSR_JAX
  
  DOI: 10.1002/advs.202410058
  
  Resource: None
  
  Curator: @inessasarian
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282 RRIDCUR:Unresolved
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RRID:IMSR_JAX:020282

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scibot

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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202410058
Jun 2024
www.sciencedirect.com www.sciencedirect.com

Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells

1
1. scibot 07 Jun 2024
  
  in Public
  
  RRID:IMSR_JAX:020282
  
  DOI: 10.1016/j.cell.2024.05.001
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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sciencedirect.com/science/article/pii/S0092867424004914
May 2024
www.sciencedirect.com www.sciencedirect.com

Epithelial aPKC deficiency leads to stem cell loss preceding metaplasia in colorectal cancer initiation

1
1. scibot 30 May 2024
  
  in Public
  
  020282
  
  DOI: 10.1016/j.devcel.2024.05.001
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282 DOI:10.1016/j.devcel.2024.05.001
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DOI:10.1016/j.devcel.2024.05.001

RRID:IMSR_JAX:020282

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scibot

URL

sciencedirect.com/science/article/pii/S1534580724002995
www.sciencedirect.com www.sciencedirect.com

Tuft cell-derived acetylcholine promotes epithelial chloride secretion and intestinal helminth clearance

1
1. scibot 14 May 2024
  
  in Public
  
  020282
  
  DOI: 10.1016/j.immuni.2024.03.023
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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sciencedirect.com/science/article/pii/S1074761324001444
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Telomere dysfunction alters intestinal stem cell dynamics to promote cancer

1
1. scibot 04 Apr 2024
  
  in Public
  
  RRID:IMSR_JAX:020282
  
  DOI: 10.1016/j.devcel.2024.03.020
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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sciencedirect.com/science/article/pii/S1534580724001886
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity

1
1. scibot 07 Feb 2024
  
  in Public
  
  Jax: 020282
  
  DOI: 10.1016/j.immuni.2024.01.002
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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scibot

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sciencedirect.com/science/article/pii/S107476132400027X
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Gut mucosal cells transfer α-synuclein to the vagus nerve

1
1. scibot 20 Jan 2024
  
  in Public
  
  RRID:IMSR_JAX:020282
  
  DOI: 10.1172/jci.insight.172192
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC10795834/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Intestinal SURF4 is essential for apolipoprotein transport and lipoprotein secretion

1
1. scibot 05 Jan 2024
  
  in Public
  
  RRID:IMSR_JAX:020282
  
  DOI: 10.1016/j.molmet.2023.101847
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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RRID:IMSR_JAX:020282

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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC10755498/
Nov 2023
www.sciencedirect.com www.sciencedirect.com

TGFB1 induces fetal reprogramming and enhances intestinal regeneration

1
1. scibot 10 Nov 2023
  
  in Public
  
  JAX:020282
  
  DOI: 10.1016/j.stem.2023.09.015
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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RRID:IMSR_JAX:020282

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scibot

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sciencedirect.com/science/article/pii/S1934590923003624
Aug 2023
www.sciencedirect.com www.sciencedirect.com

Wound-healing plasticity enables clonal expansion of founder progenitor cells in colitis

1
1. scibot 31 Aug 2023
  
  in Public
  
  RRID:IMSR_JAX:020282
  
  DOI: 10.1016/j.devcel.2023.08.011
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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scibot

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sciencedirect.com/science/article/pii/S1534580723004070
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

β-Catenin Drives Butyrophilin-like Molecule Loss and γδ T-cell Exclusion in Colon Cancer

1
1. scibot 05 Aug 2023
  
  in Public
  
  RRID:IMSR_JAX:020282
  
  DOI: 10.1158/2326-6066.CIR-22-0644
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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RRID:IMSR_JAX:020282

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC10398359/
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Oncogenic K-Ras suppresses global miRNA function

1
1. scibot 06 Jul 2023
  
  in Public
  
  JAX:020282
  
  DOI: 10.1016/j.molcel.2023.06.008
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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RRID:IMSR_JAX:020282

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scibot

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sciencedirect.com/science/article/pii/S109727652300429X
Jan 2023
www.sciencedirect.com www.sciencedirect.com

A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling

1
1. scibot 19 Jan 2023
  
  in Public
  
  RRID:IMSR_JAX:020282
  
  DOI: 10.1016/j.stem.2022.12.008
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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RRID:IMSR_JAX:020282

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scibot

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sciencedirect.com/science/article/pii/S1934590922004921
May 2022
www.sciencedirect.com www.sciencedirect.com

Aryl hydrocarbon receptor signals in epithelial cells govern the recruitment and location of Helios+ Tregs in the gut

1
1. scibot 11 May 2022
  
  in Public
  
  JAX:020282
  
  DOI: 10.1016/j.celrep.2022.110773
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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RRID:IMSR_JAX:020282

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scibot

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sciencedirect.com/science/article/pii/S221112472200537X
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Immune translational control by CPEB4 regulates intestinal inflammation resolution and colorectal cancer development

2
1. scibot 11 Feb 2022
  
  in Public
  
  JAX:020282
  
  DOI: 10.1016/j.isci.2022.103790
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
2. scibot 11 Feb 2022
  
  in Public
  
  JAX:020282
  
  DOI: 10.1016/j.isci.2022.103790
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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RRID:IMSR_JAX:020282

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scibot

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sciencedirect.com/science/article/pii/S2589004222000608
Jan 2022
www.sciencedirect.com www.sciencedirect.com

Adaptive differentiation promotes intestinal villus recovery

1
1. scibot 11 Jan 2022
  
  in Public
  
  Cat# 020282
  
  DOI: 10.1016/j.devcel.2021.12.012
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRIDCUR:Missing RRID:IMSR_JAX:020282
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RRID:IMSR_JAX:020282

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/abs/pii/S1534580721010327
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inflammasome activation leads to cDC1-independent cross-priming of CD8 T cells by epithelial cell-derived antigen

1
1. scibot 07 Jan 2022
  
  in Public
  
  RRID:IMSR_JAX:020282
  
  DOI: 10.7554/eLife.72082
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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RRID:IMSR_JAX:020282

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8719880/
www.sciencedirect.com www.sciencedirect.com

Intestinal Gpr17 deficiency improves glucose metabolism by promoting GLP-1 secretion

1
1. scibot 05 Jan 2022
  
  in Public
  
  CAT#020282
  
  DOI: 10.1016/j.celrep.2021.110179
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282 RRIDCUR:Missing
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RRID:IMSR_JAX:020282

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scibot

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sciencedirect.com/science/article/pii/S221112472101679X
Sep 2021
www.sciencedirect.com www.sciencedirect.com

PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis

1
1. scibot 24 Sep 2021
  
  in Public
  
  Stock No: 020282
  
  DOI: 10.1016/j.molcel.2021.08.039
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRIDCUR:Missing RRID:IMSR_JAX:020282
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RRID:IMSR_JAX:020282

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scibot

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sciencedirect.com/science/article/pii/S1097276521007292
Jun 2021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity

1
1. scibot 09 Jun 2021
  
  in Public
  
  Stock No: 020282
  
  DOI: 10.1016/j.celrep.2021.109212
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRIDCUR:Missing RRID:IMSR_JAX:020282
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RRID:IMSR_JAX:020282

RRIDCUR:Missing

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC8258630/
May 2021
www.sciencedirect.com www.sciencedirect.com

Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer

1
1. scibot 09 May 2021
  
  in Public
  
  RRID:IMSR_JAX:020282
  
  DOI: 10.1016/j.stem.2020.07.003
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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scibot

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sciencedirect.com/science/article/pii/S1934590920303416
Feb 2021
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Tissue‐specific deletion of mouse basolateral uniporter LAT4 (Slc43a2) reveals its crucial role in small intestine and kidney amino acid transport

1
1. scibot 27 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:020282
  
  DOI: 10.1113/JP280234
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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RRID:IMSR_JAX:020282

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physoc.onlinelibrary.wiley.com/doi/10.1113/JP280234
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation

1
1. scibot 25 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:020282
  
  DOI: 10.7554/eLife.56720
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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  RRID:IMSR_JAX:020282
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RRID:IMSR_JAX:020282

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7351492/
Sep 2020
journals.plos.org journals.plos.org

Phosphorylation of mouse intestinal basolateral amino acid uniporter LAT4 is controlled by food-entrained diurnal rhythm and dietary proteins

1
1. scibot 23 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:020282
  
  DOI: 10.1371/journal.pone.0233863
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @evieth
  
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  RRID:IMSR_JAX:020282 RRIDCUR:Validated
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journals.plos.org/plosone/article
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Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer

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1. scibot 03 Sep 2020
  
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  The Jackson LaboratoryCat# 020282
  
  DOI: 10.1016/j.stem.2020.02.008
  
  Resource: (IMSR Cat# JAX_020282,RRID:IMSR_JAX:020282)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:020282
  
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sciencedirect.com/science/article/pii/S1934590920300618