60 Matching Annotations
  1. Aug 2024
  2. www.sciencedirect.com www.sciencedirect.com
    The choroid plexus synergizes with immune cells during neuroinflammation
    1
    1. scibot 01 Aug 2024
      020940

      DOI: 10.1016/j.cell.2024.07.002

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    sciencedirect.com/science/article/pii/S0092867424007177
  3. Jul 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Microglial-derived C1q integrates into neuronal ribonucleoprotein complexes and impacts protein homeostasis in the aging brain
    1
    1. scibot 19 Jul 2024
      RRID:IMSR_JAX:020940

      DOI: 10.1016/j.cell.2024.05.058

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    sciencedirect.com/science/article/pii/S0092867424006391
  5. www.sciencedirect.com www.sciencedirect.com
    Therapeutic targeting of immunometabolism reveals a critical reliance on hexokinase 2 dosage for microglial activation and Alzheimer’s progression
    1
    1. scibot 16 Jul 2024
      Jackson Laboratory)020940

      DOI: 10.1016/j.celrep.2024.114488

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    sciencedirect.com/science/article/pii/S2211124724008179
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Redefining the ontogeny of hyalocytes as yolk sac-derived tissue-resident macrophages of the vitreous body
    1
    1. scibot 06 Jul 2024
      RRID:IMSR_JAX:020940

      DOI: 10.1186/s12974-024-03110-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11223341/
  7. Jun 2024
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Macrophages upregulate mural cell-like markers and support healing of ischemic injury by adopting functions important for vascular support
    1
    1. scibot 07 Jun 2024
      RRID:IMSR_JAX:020940

      DOI: 10.1038/s44161-024-00478-0

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    pmc.ncbi.nlm.nih.gov/articles/PMC11358018/
  9. May 2024
  10. www.biorxiv.org www.biorxiv.org
    Dynamic fibroblast-immune interactions shape wound healing after brain injury
    1
    1. scibot 23 May 2024
      Jackson 020940

      DOI: 10.1101/2024.03.13.584873

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      RRID:IMSR_JAX:020940 DOI:10.1101/2024.03.13.584873
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    biorxiv.org/content/10.1101/2024.03.13.584873v1
  11. Apr 2024
  12. www.sciencedirect.com www.sciencedirect.com
    CCR2+ monocytes replenish border-associated macrophages in the diseased mouse brain
    1
    1. scibot 19 Apr 2024
      JAX:020940

      DOI: 10.1016/j.celrep.2024.114120

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    sciencedirect.com/science/article/pii/S2211124724004480
  13. Mar 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inflammatory, metabolic and sex-dependent gene-regulatory dynamics of microglia and macrophages in neonatal hippocampus after hypoxia-ischemia
    1
    1. scibot 22 Mar 2024
      RRID:IMSR_JAX:020940

      DOI: 10.1016/j.isci.2024.109346

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    ncbi.nlm.nih.gov/pmc/articles/PMC10945260/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer's and related dementias
    1
    1. scibot 16 Mar 2024
      RRID:IMSR_JAX:020940

      DOI: 10.1038/s44319-024-00077-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10933458/
  16. Feb 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Modulation of central synapse remodeling after remote peripheral injuries by the CCL2-CCR2 axis and microglia
    1
    1. scibot 22 Feb 2024
      RRID:IMSR_JAX:020940

      DOI: 10.1016/j.celrep.2024.113776

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    sciencedirect.com/science/article/pii/S2211124724001049
  18. www.embopress.org www.embopress.org
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer’s and related dementias
    1
    1. scibot 15 Feb 2024
      RRID:IMSR_JAX:020940

      DOI: 10.1038/s44319-024-00077-x

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    embopress.org/doi/10.1038/s44319-024-00077-x
  19. Jan 2024
  20. www.sciencedirect.com www.sciencedirect.com
    A comparative evaluation of the strengths and potential caveats of the microglial inducible CreER mouse models
    1
    1. scibot 18 Jan 2024
      RRID:IMSR_JAX:020940

      DOI: 10.1016/j.celrep.2023.113660

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    sciencedirect.com/science/article/pii/S2211124723016716
  21. www.nature.com www.nature.com
    Analysis of brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke
    1
    1. scibot 11 Jan 2024
      JAX:020940

      DOI: 10.1038/s41590-023-01711-x

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    nature.com/articles/s41590-023-01711-x
  22. Dec 2023
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C1q is essential for myelination in the central nervous system (CNS)
    1
    1. scibot 13 Dec 2023
      RRID:IMSR_JAX:020940

      DOI: 10.1016/j.isci.2023.108518

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    ncbi.nlm.nih.gov/pmc/articles/PMC10711495/
  24. Oct 2023
  25. 52.53.155.43 52.53.155.43
    BRI2-mediated regulation of TREM2 processing in microglia and its potential implications for Alzheimer’s disease and related dementias
    1
    1. scibot 13 Oct 2023
      RRID:IMSR_JAX:020940

      DOI: 10.1101/2023.06.14.544924

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    52.53.155.43/5afe577c269e488702b5f7086020251c9f5e047d/2023.06.14.544924v1.full-html.html
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radial glia promote microglial development through integrin αVβ8 -TGFβ1 signaling
    1
    1. scibot 12 Oct 2023
      RRID:IMSR_JAX:020940

      DOI: 10.1101/2023.07.13.548459

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    ncbi.nlm.nih.gov/pmc/articles/PMC10542141/
  27. Sep 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial network adaptations of microglia reveal sex-specific stress response after injury and UCP2 knockout
    1
    1. scibot 22 Sep 2023
      JAX: #020940

      DOI: 10.1016/j.isci.2023.107780

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC10507162/
  29. Aug 2023
  30. www.sciencedirect.com www.sciencedirect.com
    A comparative analysis of microglial inducible Cre lines
    1
    1. scibot 30 Aug 2023
      RRID:IMSR_JAX:020940

      DOI: 10.1016/j.celrep.2023.113031

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    sciencedirect.com/science/article/pii/S2211124723010422
  31. www.sciencedirect.com www.sciencedirect.com
    IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy
    1
    1. scibot 03 Aug 2023
      RRID:IMSR_JAX:020940

      DOI: 10.1016/j.celrep.2023.112889

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    sciencedirect.com/science/article/pii/S2211124723009002
  32. Jun 2023
  33. www.sciencedirect.com www.sciencedirect.com
    PD-L1/PD-1 checkpoint pathway regulates hippocampal neuronal excitability and learning and memory behavior
    1
    1. scibot 22 Jun 2023
      RRID:IMSR_JAX:020940

      DOI: 10.1016/j.neuron.2023.05.022

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    sciencedirect.com/science/article/pii/S0896627323003951
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early chronic suppression of microglial p38α in a model of Alzheimer’s disease does not significantly alter amyloid-associated neuropathology
    1
    1. scibot 03 Jun 2023
      RRID:IMSR_JAX:020940

      DOI: 10.1371/journal.pone.0286495

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    ncbi.nlm.nih.gov/pmc/articles/PMC10231773/
  35. May 2023
  36. 52.53.155.43 52.53.155.43
    Finding the right tool: a comprehensive evaluation of microglial inducible cre mouse models
    1
    1. scibot 27 May 2023
      RRID:IMSR_JAX:020940

      DOI: 10.1101/2023.04.17.536878

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    52.53.155.43/212e4b73c62c195b3a5740795c4e69d16edaaa96/2023.04.17.536878v1.full-html.html
  37. www.sciencedirect.com www.sciencedirect.com
    Tissue-resident, extravascular Ly6c− monocytes are critical for inflammation in the synovium
    1
    1. scibot 19 May 2023
      JAX:020940

      DOI: 10.1016/j.celrep.2023.112513

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    sciencedirect.com/science/article/pii/S2211124723005247
  38. Apr 2023
  39. www.biorxiv.org www.biorxiv.org
    Brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke
    1
    1. scibot 20 Apr 2023
      JAX:020940

      DOI: 10.1101/2023.03.31.535150

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    biorxiv.org/content/10.1101/2023.03.31.535150v1
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Group 2 innate lymphoid cells promote inhibitory synapse development and social behavior
    1
    1. scibot 09 Apr 2023
      RRID:IMSR_JAX:020940

      DOI: 10.1101/2023.03.16.532850

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    ncbi.nlm.nih.gov/pmc/articles/PMC10055027/
  41. Mar 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Real-time mechanisms of exacerbated synaptic remodeling by microglia in acute models of systemic inflammation and tauopathy
    1
    1. scibot 10 Mar 2023
      RRID:IMSR_JAX:020940

      DOI: 10.1016/j.bbi.2023.02.023

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    sciencedirect.com/science/article/pii/S0889159123000545
  43. www.sciencedirect.com www.sciencedirect.com
    Apoptotic cell fragments locally activate tingible body macrophages in the germinal center
    1
    1. scibot 03 Mar 2023
      JAX:020

      DOI: 10.1016/j.cell.2023.02.004

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      Curator: @sofiakhan13

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    sciencedirect.com/science/article/pii/S009286742300106X
  44. Feb 2023
  45. dm5migu4zj3pb.cloudfront.net dm5migu4zj3pb.cloudfront.net
    161507.1-20230126111242-covered-e0fd13ba177f913fd3156f593ead4cfd.pdf
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    1. scibot 07 Feb 2023
      020940

      DOI: 10.1172/JCI161507

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      Curator: @bandrow

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    dm5migu4zj3pb.cloudfront.net/manuscripts/161000/161507/cache/161507.1-20230126111242-covered-e0fd13ba177f913fd3156f593ead4cfd.pdf
  46. Dec 2022
  47. link.springer.com link.springer.com
    Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina
    1
    1. scibot 15 Dec 2022
      RRID:IMSR_JAX:020940

      DOI: 10.1186/s12974-022-02659-9

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    link.springer.com/article/10.1186/s12974-022-02659-9
  48. www.sciencedirect.com www.sciencedirect.com
    Gut microbiota promotes stem cell differentiation through macrophage and mesenchymal niches in early postnatal development
    1
    1. scibot 06 Dec 2022
      RRID:IMSR_JAX:020940

      DOI: 10.1016/j.immuni.2022.11.003

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    sciencedirect.com/science/article/pii/S1074761322005933
  49. www.sciencedirect.com www.sciencedirect.com
    Mouse placenta fetal macrophages arise from endothelial cells outside the placenta
    1
    1. scibot 06 Dec 2022
      JAX:020940

      DOI: 10.1016/j.devcel.2022.11.003

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    sciencedirect.com/science/article/pii/S1534580722007821
  50. Oct 2022
  51. www.sciencedirect.com www.sciencedirect.com
    SYK coordinates neuroprotective microglial responses in neurodegenerative disease
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    1. scibot 20 Oct 2022
      020940

      DOI: 10.1016/j.cell.2022.09.030

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    sciencedirect.com/science/article/pii/S0092867422012491
  52. www.sciencedirect.com www.sciencedirect.com
    Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation
    1
    1. scibot 13 Oct 2022
      JAX:020940

      DOI: 10.1016/j.immuni.2022.09.005

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    sciencedirect.com/science/article/pii/S107476132200499X
  53. Jun 2022
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria
    1
    1. scibot 15 Jun 2022
      RRID:IMSR_JAX:020940

      DOI: 10.7554/eLife.68598

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    ncbi.nlm.nih.gov/pmc/articles/PMC9183236/
  55. Mar 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions
    1
    1. scibot 26 Mar 2022
      RRID:IMSR_JAX:020940

      DOI: 10.1084/jem.20211071

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    ncbi.nlm.nih.gov/pmc/articles/PMC8932534/
  57. Feb 2022
  58. journals.plos.org journals.plos.org
    The NKCC1 ion transporter modulates microglial phenotype and inflammatory response to brain injury in a cell-autonomous manner
    1
    1. scibot 05 Feb 2022
      RRID:IMSR_JAX:020940JAX

      DOI: 10.1371/journal.pbio.3001526

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      Curator: @evieth

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    journals.plos.org/plosbiology/article
  59. Jan 2022
  60. www.sciencedirect.com www.sciencedirect.com
    Helminth resistance is mediated by differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion
    1
    1. scibot 12 Jan 2022
      JAX:020940

      DOI: 10.1016/j.celrep.2021.110215

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    sciencedirect.com/science/article/pii/S2211124721017198
  61. Sep 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave
    1
    1. scibot 14 Sep 2021
      RRID:IMSR_JAX:020940

      DOI: 10.7554/eLife.66738

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    ncbi.nlm.nih.gov/pmc/articles/PMC8425950/
  63. Aug 2021
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair
    1
    1. scibot 05 Aug 2021
      RRID:IMSR_JAX:020940

      DOI: 10.7554/eLife.68603

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    ncbi.nlm.nih.gov/pmc/articles/PMC8318592/
  65. www.sciencedirect.com www.sciencedirect.com
    Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain
    1
    1. scibot 04 Aug 2021
      RRID:IMSR_JAX020940

      DOI: 10.1016/j.immuni.2017.05.003

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    sciencedirect.com/science/article/pii/S1074761317302194
  66. Jul 2021
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Beneficial and Detrimental Remodeling of Glial Connexin and Pannexin Functions in Rodent Models of Nervous System Diseases
    1
    1. scibot 30 Jul 2021
      JAX:020940

      DOI: 10.3389/fncel.2019.00491

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    ncbi.nlm.nih.gov/pmc/articles/PMC6851021/
  68. www.sciencedirect.com www.sciencedirect.com
    Microglial UCP2 Mediates Inflammation and Obesity Induced by High-Fat Feeding
    1
    1. scibot 29 Jul 2021
      Jackson Laboratory#020940

      DOI: 10.1016/j.cmet.2019.08.010

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    sciencedirect.com/science/article/pii/S1550413119304395
  69. www.eneuro.org www.eneuro.org
    Targeting microglia using Cx3cr1-cre lines: revisiting the specificity
    1
    1. scibot 29 Jul 2021
      B6.129P2(C)-Cx3cr1tm2.1(cre/ERT2)Jung /J

      DOI: 10.1523/ENEURO.0114-19.2019

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    eneuro.org/content/6/4/ENEURO.0114-19.2019
  70. www.sciencedirect.com www.sciencedirect.com
    Microglia enable mature perineuronal nets disassembly upon anesthetic ketamine exposure or 60-Hz light entrainment in the healthy brain
    1
    1. scibot 09 Jul 2021
      Cat#020940

      DOI: 10.1016/j.celrep.2021.109313

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    sciencedirect.com/science/article/pii/S2211124721006896
  71. Apr 2021
  72. www.sciencedirect.com www.sciencedirect.com
    Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity
    1
    1. scibot 23 Apr 2021
      RRID:IMSR_JAX:020940

      DOI: 10.1016/j.cell.2020.05.050

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    sciencedirect.com/science/article/pii/S0092867420306838
  73. Feb 2021
  74. www.sciencedirect.com www.sciencedirect.com
    Brainwide Genetic Sparse Cell Labeling to Illuminate the Morphology of Neurons and Glia with Cre-Dependent MORF Mice
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    1. scibot 27 Feb 2021
      JAX:020940

      DOI: 10.1016/j.neuron.2020.07.019

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    sciencedirect.com/science/article/pii/S0896627320305638
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain
    1
    1. scibot 26 Feb 2021
      RRID:IMSR_JAX:020940

      DOI: 10.7554/eLife.57495

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    ncbi.nlm.nih.gov/pmc/articles/PMC7367682/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A new genetic strategy for targeting microglia in development and disease
    1
    1. scibot 24 Feb 2021
      MGI:5467985

      DOI: 10.7554/eLife.54590

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    ncbi.nlm.nih.gov/pmc/articles/PMC7375817/
  77. Dec 2020
  78. www.nature.com www.nature.com
    Negative feedback control of neuronal activity by microglia
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    1. scibot 31 Dec 2020
      020940

      DOI: 10.1038/s41586-020-2777-8

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    nature.com/articles/s41586-020-2777-8
  79. www.sciencedirect.com www.sciencedirect.com
    Protocol for brain-wide or region-specific microglia depletion and repopulation in adult mice
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    1. scibot 16 Dec 2020
      RRID:IMSR_JAX:020940

      DOI: 10.1016/j.xpro.2020.100211

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    sciencedirect.com/science/article/pii/S2666166720301982
  80. Sep 2020
  81. www.sciencedirect.com www.sciencedirect.com
    Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner
    1
    1. scibot 23 Sep 2020
      RRID:IMSR_JAX:020940

      DOI: 10.1016/j.cell.2020.02.013

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    sciencedirect.com/science/article/pii/S0092867420301574
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Yolk-sac-derived macrophages progressively expand in the mouse kidney with age
    1
    1. scibot 16 Sep 2020
      RRID:IMSR_JAX:020940

      DOI: 10.7554/eLife.51756

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    ncbi.nlm.nih.gov/pmc/articles/PMC7205460/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Light-induced engagement of microglia to focally remodel synapses in the adult brain
    1
    1. scibot 09 Sep 2020
      RRID:IMSR_JAX:020940

      DOI: 10.7554/eLife.58435

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    ncbi.nlm.nih.gov/pmc/articles/PMC7470825/
  84. Jan 2020
  85. www.eneuro.org www.eneuro.org
    Removal of the potassium chloride co-transporter from the somatodendritic membrane of axotomized motoneurons is independent of BDNF/TrkB signaling but is controlled by neuromuscular innervation
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:020940

      DOI: 10.1523/ENEURO.0172-19.2019

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    eneuro.org/content/6/5/ENEURO.0172-19.2019
  86. www.eneuro.org www.eneuro.org
    Targeting microglia using Cx3cr1-cre lines: revisiting the specificity
    2
    1. scibot 13 Jan 2020
      JAX:020940

      DOI: 10.1523/ENEURO.0114-19.2019

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    2. scibot 13 Jan 2020
      JAX:020940

      DOI: 10.1523/ENEURO.0114-19.2019

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    eneuro.org/content/6/4/ENEURO.0114-19.2019
  87. www.jneurosci.org www.jneurosci.org
    Spinal Motor Circuit Synaptic Plasticity after Peripheral Nerve Injury Depends on Microglia Activation and a CCR2 Mechanism
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:020940

      DOI: 10.1523/JNEUROSCI.2945-17.2019

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    jneurosci.org/content/39/18/3412
  88. Apr 2019
  89. www.sciencedirect.com www.sciencedirect.com
    Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain
    1
    1. scibot 05 Apr 2019
      IMSR_JAX020940

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1074761317302194
  90. Nov 2018
  91. www.sciencedirect.com www.sciencedirect.com
    Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping
    1
    1. scibot 05 Nov 2018
      020940

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0092867418309772
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner
    1
    1. scibot 05 Nov 2018
      JAX:020940

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC5786503/