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37 Matching Annotations

Aug 2025
www.cell.com www.cell.com

Integrated time-series analysis and high-content CRISPR screening delineate the dynamics of macrophage immune regulation

1
1. scibot 13 Aug 2025
  
  in Public
  
  RRID:IMSR_JAX:024858
  
  DOI: 10.1016/j.cels.2025.101346
  
  Resource: RRID:IMSR_JAX:024858
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:024858
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cell.com/cell-systems/abstract/S2405-4712(25)00179-6
Jun 2025
www.sciencedirect.com www.sciencedirect.com

TAMs-specific ARF1 inhibition reprograms glioma microenvironment and enhances the therapeutic effect of oncolytic adenovirus

1
1. scibot 04 Jun 2025
  
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  Jackson Laboratory (America)Cat#024858
  
  DOI: 10.1016/j.isci.2025.112696
  
  Resource: RRID:IMSR_JAX:024858
  
  Curator: @areedewitt04
  
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  RRID:IMSR_JAX:024858
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sciencedirect.com/science/article/pii/S2589004225009575
May 2025
www.sciencedirect.com www.sciencedirect.com

Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target

1
1. scibot 17 May 2025
  
  in Public
  
  The Jackson LaboratoryStrain #:024858
  
  DOI: 10.1016/j.ccell.2025.04.014
  
  Resource: RRID:IMSR_JAX:024858
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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RRID:IMSR_JAX:024858

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sciencedirect.com/science/article/pii/S1535610825001734
Apr 2025
www.sciencedirect.com www.sciencedirect.com

Hypothalamic PNOC/NPY neurons constitute mediators of leptin-controlled energy homeostasis

1
1. scibot 24 Apr 2025
  
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  Jackson LaboratoriesStock #024858
  
  DOI: 10.1016/j.cell.2025.04.001
  
  Resource: RRID:IMSR_JAX:024858
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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scibot

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sciencedirect.com/science/article/pii/S0092867425004039
www.sciencedirect.com www.sciencedirect.com

ZEB2 is a master switch controlling the tumor-associated macrophage program

1
1. scibot 11 Apr 2025
  
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  The Jackson Laboratories024858
  
  DOI: 10.1016/j.ccell.2025.03.021
  
  Resource: RRID:IMSR_JAX:024858
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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sciencedirect.com/science/article/pii/S1535610825001229
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Contrasting cytotoxic and regulatory T cell responses underlying distinct clinical outcomes to anti-PD-1 plus lenvatinib therapy in cancer

1
1. scibot 31 Jan 2025
  
  in Public
  
  Jackson LaboratoryStock No: 024858
  
  DOI: 10.1016/j.ccell.2025.01.001
  
  Resource: RRID:IMSR_JAX:024858
  
  Curator: @areedewitt04
  
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  RRID:IMSR_JAX:024858
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sciencedirect.com/science/article/pii/S1535610825000194
www.sciencedirect.com www.sciencedirect.com

Calcineurin: An essential regulator of sleep revealed by biochemical, chemical biological, and genetic approaches

1
1. scibot 03 Jan 2025
  
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  RRID:IMSR_JAX:024858
  
  DOI: 10.1016/j.chembiol.2024.12.003
  
  Resource: RRID:IMSR_JAX:024858
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:024858
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sciencedirect.com/science/article/pii/S2451945624005130
Dec 2024
www.biorxiv.org www.biorxiv.org

Activity-Dependent Localization and Heterogeneous Dynamics of STIM1 and STIM2 at ER-PM contacts in Hippocampal Neurons

1
1. scibot 29 Dec 2024
  
  in Public
  
  RRID:IMSR_JAX:024858
  
  DOI: 10.1101/2024.12.23.630200
  
  Resource: RRID:IMSR_JAX:024858
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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biorxiv.org/content/10.1101/2024.12.23.630200v1
Oct 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CRISPR–Cas9 screens reveal regulators of ageing in neural stem cells

1
1. scibot 08 Oct 2024
  
  in Public
  
  strain/024858
  
  DOI: 10.1038/s41586-024-07972-2
  
  Resource: RRID:IMSR_JAX:024858
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  DOI:10.1038/s41586-024-07972-2 RRID:IMSR_JAX:024858
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DOI:10.1038/s41586-024-07972-2

RRID:IMSR_JAX:024858

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC11525198/
Sep 2024
www.nature.com www.nature.com

Self-sustaining long-term 3D epithelioid cultures reveal drivers of clonal expansion in esophageal epithelium

1
1. scibot 27 Sep 2024
  
  in Public
  
  RRID:IMSR_JAX:024858
  
  DOI: 10.1038/s41588-024-01875-8
  
  Resource: RRID:IMSR_JAX:024858
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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RRID:IMSR_JAX:024858

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nature.com/articles/s41588-024-01875-8
Mar 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

An oocyte-specific Cas9-expressing mouse for germline CRISPR/Cas9-mediated genome editing

1
1. scibot 26 Mar 2024
  
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  RRID:IMSR_JAX:024858
  
  DOI: 10.1002/dvg.23589
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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onlinelibrary.wiley.com/doi/10.1002/dvg.23589
Feb 2024
www.science.org www.science.org

Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery

1
1. scibot 29 Feb 2024
  
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  RRID:IMSR_JAX:024858
  
  DOI: 10.1126/sciadv.adk3127
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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RRID:IMSR_JAX:024858

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scibot

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science.org/doi/10.1126/sciadv.adk3127
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery

1
1. scibot 28 Feb 2024
  
  in Public
  
  RRID:IMSR_JAX:024858
  
  DOI: 10.1126/sciadv.adk3127
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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ncbi.nlm.nih.gov/pmc/articles/PMC10889360/
Dec 2023
www.sciencedirect.com www.sciencedirect.com

SON is an essential m6A target for hematopoietic stem cell fate

1
1. scibot 17 Dec 2023
  
  in Public
  
  The Jackson LaboratoryStrain #024858
  
  DOI: 10.1016/j.stem.2023.11.006
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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RRID:IMSR_JAX:024858

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sciencedirect.com/science/article/pii/S1934590923003983
Mar 2023
www.sciencedirect.com www.sciencedirect.com

Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion

1
1. scibot 23 Mar 2023
  
  in Public
  
  RRID:IMSR_JAX:024858
  
  DOI: 10.1016/j.molcel.2023.02.026
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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RRID:IMSR_JAX:024858

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sciencedirect.com/science/article/pii/S1097276523001533
Jan 2023
www.sciencedirect.com www.sciencedirect.com

Ventral tegmental area astrocytes modulate cocaine reward by tonically releasing GABA

1
1. scibot 21 Jan 2023
  
  in Public
  
  RRID:IMSR_JAX:024858
  
  DOI: 10.1016/j.neuron.2022.12.033
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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RRID:IMSR_JAX:024858

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sciencedirect.com/science/article/pii/S0896627322011540
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation

1
1. scibot 24 Nov 2022
  
  in Public
  
  RRID:IMSR_JAX:024858
  
  DOI: 10.1016/j.molcel.2022.11.002
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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RRID:IMSR_JAX:024858

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sciencedirect.com/science/article/abs/pii/S1097276522010644
Jul 2022
www.sciencedirect.com www.sciencedirect.com

Template-independent genome editing in the Pcdh15av−3j mouse, a model of human DFNB23 nonsyndromic deafness

2
1. scibot 13 Jul 2022
  
  in Public
  
  JAX: 024858
  
  DOI: 10.1016/j.celrep.2022.111061
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
2. scibot 13 Jul 2022
  
  in Public
  
  JAX:024858
  
  DOI: 10.1016/j.celrep.2022.111061
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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RRID:IMSR_JAX:024858

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sciencedirect.com/science/article/pii/S2211124722008592
Apr 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SLC38A2 provides proline to fulfill unique synthetic demands arising during osteoblast differentiation and bone formation

1
1. scibot 15 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:024858
  
  DOI: 10.7554/eLife.76963
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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RRID:IMSR_JAX:024858

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9007586/
Dec 2021
www.sciencedirect.com www.sciencedirect.com

Chronic calcium signaling in IgE+ B cells limits plasma cell differentiation and survival

2
1. scibot 08 Dec 2021
  
  in Public
  
  RRID:IMSR_JAX:024858
  
  DOI: 10.1016/j.immuni.2021.11.006
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
  What is this?
  
  RRID:IMSR_JAX:024858
2. scibot 08 Dec 2021
  
  in Public
  
  RRID:IMSR_JAX
  
  DOI: 10.1016/j.immuni.2021.11.006
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
  Curator comments: STOCK Gt(ROSA)26Sortm1.1(CAG-cas9*,-EGFP)Fezh/J Mus musculus
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_JAX:024858 RRIDCUR:SyntaxError
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RRIDCUR:SyntaxError

RRIDCUR:Unresolved

RRID:IMSR_JAX:024858

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scibot

URL

sciencedirect.com/science/article/pii/S1074761321004970
Nov 2021
www.sciencedirect.com www.sciencedirect.com

MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function

1
1. scibot 12 Nov 2021
  
  in Public
  
  JAX:024858
  
  DOI: 10.1016/j.immuni.2021.10.011
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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sciencedirect.com/science/article/pii/S1074761321004489
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SLC1A5 provides glutamine and asparagine necessary for bone development in mice

1
1. scibot 05 Nov 2021
  
  in Public
  
  RRID:IMSR_JAX:024858
  
  DOI: 10.7554/eLife.71595
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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RRID:IMSR_JAX:024858

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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC8553342/
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice

1
1. scibot 17 Aug 2021
  
  in Public
  
  Jackson LaboratoryStock# 024858
  
  DOI: 10.7554/eLife.68227
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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ncbi.nlm.nih.gov/pmc/articles/PMC8360648/
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:024858
  
  DOI: 10.1016/j.cell.2018.10.001
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRIDCUR:Validated RRID:IMSR_JAX:024858
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RRIDCUR:Validated

RRID:IMSR_JAX:024858

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scibot

URL

sciencedirect.com/science/article/pii/S0092867418313096
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 29 Jul 2021
  
  in Public
  
  JAX:024858
  
  DOI: 10.1016/j.cmet.2017.08.024
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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ncbi.nlm.nih.gov/pmc/articles/PMC5677551/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Synapse maintenance and restoration in the retina by NGL2

2
1. scibot 29 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:024858
  
  DOI: 10.7554/eLife.30388
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
  What is this?
  
  RRID:IMSR_JAX:024858 RRIDCUR:Duplicate RRIDCUR:Validated
2. scibot 29 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:024858
  
  DOI: 10.7554/eLife.30388
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858 RRIDCUR:Validated
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RRIDCUR:Validated

RRIDCUR:Duplicate

RRID:IMSR_JAX:024858

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5882244/
Mar 2021
www.nature.com www.nature.com

Lineage barcoding in mice with homing CRISPR

1
1. scibot 18 Mar 2021
  
  in Public
  
  RRID:IMSR_JAX:024858
  
  DOI: 10.1038/s41596-020-00485-y
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:024858

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nature.com/articles/s41596-020-00485-y
Feb 2021
elifesciences.org elifesciences.org

Genetic dissection of the different roles of hypothalamic kisspeptin neurons in regulating female reproduction

1
1. scibot 26 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:024858
  
  DOI: 10.7554/eLife.43999
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
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  RRID:IMSR_JAX:024858
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elifesciences.org/articles/43999
Sep 2020
www.nature.com www.nature.com

Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

1
1. scibot 03 Sep 2020
  
  in Public
  
  JAX stock no. 024858
  
  DOI: 10.1038/s41467-020-14309-w
  
  Resource: (IMSR Cat# JAX_024858,RRID:IMSR_JAX:024858)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
  Curator comments: IMSR Cat# JAX:024858, STOCK Gt(ROSA)26Sortm1.1(CAG-cas9*,-EGFP)Fezh/J Mus musculus
  
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  RRIDCUR:Missing RRID:IMSR_JAX:024858
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RRIDCUR:Missing

RRID:IMSR_JAX:024858

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nature.com/articles/s41467-020-14309-w
Nov 2018
www.sciencedirect.com www.sciencedirect.com

A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response

1
1. scibot 05 Nov 2018
  
  in Public
  
  JAX:024858
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:024858
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:024858 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:024858

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scibot

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sciencedirect.com/science/article/pii/S0092867418301090
www.sciencedirect.com www.sciencedirect.com

In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation

1
1. scibot 05 Nov 2018
  
  in Public
  
  JAX:024858
  
  Resource used:
  
  RRID:IMSR_JAX:024858
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:024858
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RRID:IMSR_JAX:024858

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scibot

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sciencedirect.com/science/article/pii/S0092867417312473
www.cell.com www.cell.com

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  JAX:024858
  
  Resource used:
  
  RRID:IMSR_JAX:024858
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:024858
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RRID:IMSR_JAX:024858

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scibot

URL

cell.com/cell/abstract/S0092-8674(17)31247-3
Nov 2017
www.sciencedirect.com www.sciencedirect.com

The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D

1
1. scibot 08 Nov 2017
  
  in Public
  
  JAX:024858
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:024858
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:024858 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:024858

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S155041311730551X
www.cell.com www.cell.com

Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq

1
1. scibot 08 Nov 2017
  
  in Public
  
  024858
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:024858
  
  SciCrunch record: RRID:IMSR_JAX:024858
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:024858 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:IMSR_JAX:024858

Annotators

scibot

URL

cell.com/cell/fulltext/S0092-8674(16)31611-7