26 Matching Annotations
  1. Aug 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    JNK and p53 cause human and mouse β cell death during excessive unfolded protein response
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    pmc.ncbi.nlm.nih.gov/articles/PMC13430013/
  3. Apr 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2212877826000554-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC13158791/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Type 2 diabetes risk alleles in peptidyl-glycine alpha-amidating monooxygenase influence GLP-1 levels and response to GLP-1 receptor agonists
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    pmc.ncbi.nlm.nih.gov/articles/PMC13072570/
  6. Mar 2026
  7. www.sciencedirect.com www.sciencedirect.com
    BAF60C links nucleolar stress to β cell dysfunction in type 2 diabetes through controlling Reg3b mRNA decay
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    sciencedirect.com/science/article/pii/S1534580726000717
  8. Feb 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intravital imaging reveals glucose-dependent cilia movement in pancreatic islets in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC11718731/
  10. Dec 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lipopolysaccharide-induced cytokine signaling activates a temporal innate defense program and represses pancreatic β-cell identity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12663513/
  12. Aug 2025
  13. www.cell.com www.cell.com
    HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes
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    cell.com/cell-metabolism/abstract/S1550-4131(25)00334-1
  14. Jul 2025
  15. dx.doi.org dx.doi.org
    Dynamic Ca2+-Dependent Transcription Links Metabolic Stress to Impaired β-Cell Identity
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    dx.doi.org/10.2337/db24-1141
  16. Jun 2025
  17. 52.53.155.43 52.53.155.43
    Deletion of Ascl1 in pancreatic β-cells improves insulin secretion, promotes parasympathetic innervation, and attenuates dedifferentiation during metabolic stress
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    52.53.155.43/b1a8b4466726dfc851796ffaf4a6ed2d264a732e/Online_Supplemental_Materials_5-html.html
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types
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    pmc.ncbi.nlm.nih.gov/articles/PMC11381023/
  19. Feb 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11814175/
  21. Aug 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual role of neuroplastin in pancreatic β cells: Regulating insulin secretion and promoting islet inflammation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11331099/
  23. Jan 2024
  24. www.sciencedirect.com www.sciencedirect.com
    TALK-1-mediated alterations of β-cell mitochondrial function and insulin secretion impair glucose homeostasis on a diabetogenic diet
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    sciencedirect.com/science/article/pii/S2211124724000019
  25. link.springer.com link.springer.com
    NRF2 is required for neonatal mouse beta cell growth by maintaining redox balance and promoting mitochondrial biogenesis and function
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    link.springer.com/article/10.1007/s00125-023-06071-7
  26. Sep 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10482429/
  28. Aug 2023
  29. link.springer.com link.springer.com
    SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells
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    link.springer.com/article/10.1007/s00125-023-05979-4
  30. Jun 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Pancreatic islet protection at the expense of secretory function involves serine-linked mitochondrial one-carbon metabolism
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    sciencedirect.com/science/article/pii/S2211124723006265
  32. May 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Vitamin K-dependent carboxylation regulates Ca2+ flux and adaptation to metabolic stress in β cells
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    sciencedirect.com/science/article/pii/S2211124723005119
  34. Jan 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma
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    sciencedirect.com/science/article/pii/S1534580722008942
  36. Jun 2022
  37. www.sciencedirect.com www.sciencedirect.com
    IL18 signaling causes islet β cell development and insulin secretion via different receptors on acinar and β cells
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    sciencedirect.com/science/article/pii/S1534580722003707
  38. Feb 2022
  39. www.sciencedirect.com www.sciencedirect.com
    A distinct hypothalamus-to-β cell circuit modulates insulin secretion
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    sciencedirect.com/science/article/pii/S1550413121006574
  40. Jul 2021
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced synchroneity of intra-islet Ca2+ oscillations in vivo in Robo-deficient β cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8289414/
  42. Feb 2021
  43. www.nature.com www.nature.com
    PDX1 LOW MAFA LOW β-cells contribute to islet function and insulin release
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    nature.com/articles/s41467-020-20632-z
  44. Sep 2020
  45. www.nature.com www.nature.com
    Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
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    nature.com/articles/s41467-020-14309-w
  46. Aug 2020
  47. www.jci.org www.jci.org
    Sel1L-Hrd1 ER-associated degradation maintains β-cell identity via TGFβ signaling
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    jci.org/articles/view/134874