Hypothesis

32 Matching Annotations

Sep 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Strong sustained type I IFN signaling acts cell intrinsically to impair IFNγ responses and cause tuberculosis susceptibility

1
1. scibot 02 Sep 2026
  
  in Public
  
  RRID:IMSR_JAX:028
  
  DOI: 10.1016/j.chom.2026.07.014
  
  Resource: RRID:IMSR_JAX:028256
  
  Curator: @sonofthor
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_JAX:028256
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RRIDCUR:Unresolved

RRID:IMSR_JAX:028256

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC13528601/
Jun 2026
www.sciencedirect.com www.sciencedirect.com

Type I interferon signaling in hematopoietic cells impairs neutrophil antibacterial function in the middle ear during viral co-infection

2
1. scibot 04 Jun 2026
  
  in Public
  
  RRID:IMSR_JAX:028256
  
  DOI: 10.1016/j.xcrm.2026.102846
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
2. scibot 04 Jun 2026
  
  in Public
  
  The Jackson Laboratory_028256
  
  DOI: 10.1016/j.xcrm.2026.102846
  
  Resource: RRID:IMSR_JAX:028256
  
  Curator: @nmaralla
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_JAX:028256
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RRIDCUR:Unresolved

RRID:IMSR_JAX:028256

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scibot

URL

sciencedirect.com/science/article/pii/S2666379126002636
Mar 2026
www.sciencedirect.com www.sciencedirect.com

B cell-intrinsic type I interferon signaling contributes to defective antibody responses to a model antigen during persistent LCMV infection

1
1. scibot 24 Mar 2026
  
  in Public
  
  RRID:IMSR_JAX:028256
  
  DOI: 10.1016/j.celrep.2026.117145
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

sciencedirect.com/science/article/pii/S2211124726002238
Jan 2026
www.sciencedirect.com www.sciencedirect.com

MyD88 signaling in myeloid cells induces gastrointestinal tract injury and systemic inflammation after West Nile virus infection

1
1. scibot 22 Jan 2026
  
  in Public
  
  RRID:IMSR_JAX:028256
  
  DOI: 10.1016/j.celrep.2025.116852
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

sciencedirect.com/science/article/pii/S2211124725016249
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

1
1. scibot 17 Dec 2025
  
  in Public
  
  Jackson Laboratory Cat_028256
  
  DOI: 10.1016/j.cell.2025.11.023
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_JAX:028256
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RRIDCUR:Unresolved

RRID:IMSR_JAX:028256

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scibot

URL

sciencedirect.com:5037/science/article/pii/S0092867425013583
Nov 2025
www.biorxiv.org www.biorxiv.org

Lymphatic constraint of germinal centers optimizes protective antibody responses

1
1. scibot 11 Nov 2025
  
  in Public
  
  stock no.028256
  
  DOI: 10.1101/2025.11.03.686378
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

biorxiv.org/content/10.1101/2025.11.03.686378v1
Oct 2025
www.sciencedirect.com www.sciencedirect.com

Intravascular immune surveillance against viremia requires spatiotemporal coordination between Kupffer cells and ILC1s

1
1. scibot 30 Oct 2025
  
  in Public
  
  RRID:IMSR_JAX:028256
  
  DOI: 10.1016/j.celrep.2025.116488
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

sciencedirect.com/science/article/pii/S2211124725012598
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Structure of gut microbial glycolipid modulates host inflammatory response

1
1. scibot 23 Jul 2025
  
  in Public
  
  RRID: IMSR_JAX:028256
  
  DOI: 10.1016/j.cell.2025.05.016
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

sciencedirect.com/science/article/pii/S0092867425005665
Jun 2025
www.nature.com www.nature.com

Environmental stress drives clearance of a persistent enteric virus in mice

1
1. scibot 28 Jun 2025
  
  in Public
  
  # 028256
  
  DOI: 10.1038/s41564-025-02046-z
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

nature.com/articles/s41564-025-02046-z
www.thelancet.com www.thelancet.com

MyD88 signalling in B cells and antibody responses during Oropouche virus-induced neurological disease in mice

1
1. scibot 26 Jun 2025
  
  in Public
  
  RRID:IMSR_JAX:028256
  
  DOI: 10.1016/j.ebiom.2025.105815
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00259-2/abstract
May 2025
www.sciencedirect.com www.sciencedirect.com

Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling

1
1. scibot 17 May 2025
  
  in Public
  
  RRID:IMSR_JAX:028256
  
  DOI: 10.1016/j.immuni.2025.04.001
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

sciencedirect.com/science/article/pii/S1074761325001645
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

cGAS and STING in Host Myeloid Cells Are Essential for Effective Cyclophosphamide Treatment of Advanced Breast Cancer

1
1. scibot 19 Apr 2025
  
  in Public
  
  RRID:IMSR_JAX:028256
  
  DOI: 10.3390/cancers17071130
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11987962/
www.sciencedirect.com www.sciencedirect.com

Type I interferons induce guanylate-binding proteins and lysosomal defense in hepatocytes to control malaria

1
1. scibot 01 Apr 2025
  
  in Public
  
  JAX:028256
  
  DOI: 10.1016/j.chom.2025.03.008
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

sciencedirect.com/science/article/pii/S1931312825000915
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ACNP 62nd Annual Meeting: Panels, Mini-Panels and Study Groups

1
1. scibot 17 Dec 2024
  
  in Public
  
  028256
  
  DOI: 10.1038/s41386-023-01754-6
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @AleksanderDrozdz
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC10729591/
Aug 2024
www.sciencedirect.com www.sciencedirect.com

Obesity intensifies sex-specific interferon signaling to selectively worsen central nervous system autoimmunity in females

1
1. scibot 22 Aug 2024
  
  in Public
  
  RRID:IMSR_JAX:028256
  
  DOI: 10.1016/j.cmet.2024.07.017
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

sciencedirect.com/science/article/pii/S1550413124002882
Mar 2024
www.sciencedirect.com www.sciencedirect.com

Type-I-interferon-responsive microglia shape cortical development and behavior

2
1. scibot 15 Mar 2024
  
  in Public
  
  RRID:IMSR_JAX:028256
  
  DOI: 10.1016/j.cell.2024.02.020
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
2. scibot 15 Mar 2024
  
  in Public
  
  RRID:IMSR_JAX:028256
  
  DOI: 10.1016/j.cell.2024.02.020
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

sciencedirect.com/science/article/pii/S0092867424001867
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity

1
1. scibot 04 Jan 2024
  
  in Public
  
  028256
  
  DOI: 10.1016/j.cell.2023.05.039
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867423005913
Dec 2023
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis

1
1. scibot 02 Dec 2023
  
  in Public
  
  RRID:IMSR_JAX:028256
  
  DOI: 10.1016/j.cell.2023.11.002
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC10757650/
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Zika virus spreads through infection of lymph node-resident macrophages

1
1. scibot 16 Feb 2023
  
  in Public
  
  RRID:IMSR_JAX:028
  
  DOI: 10.1016/j.celrep.2023.112126
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @sofiakhan13
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256 RRIDCUR:Unresolved
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Tags

RRIDCUR:Unresolved

RRID:IMSR_JAX:028256

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723001377
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Chronic type I interferon signaling promotes lipid-peroxidation-driven terminal CD8+ T cell exhaustion and curtails anti-PD-1 efficacy

1
1. scibot 16 Nov 2022
  
  in Public
  
  RRID:IMSR_JAX:028256
  
  DOI: 10.1016/j.celrep.2022.111647
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722015182
www.sciencedirect.com www.sciencedirect.com

Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity

1
1. scibot 10 Nov 2022
  
  in Public
  
  RRID:IMSR_JAX:028256
  
  DOI: 10.1016/j.celrep.2022.111593
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722014589
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier

1
1. scibot 27 Oct 2022
  
  in Public
  
  JAX:028256
  
  DOI: 10.7554/eLife.80690
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9596162/
Apr 2022
www.sciencedirect.com www.sciencedirect.com

Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques

1
1. scibot 20 Apr 2022
  
  in Public
  
  The Jackson LaboratoriesStrain #028256
  
  DOI: 10.1016/j.immuni.2022.03.018
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

sciencedirect.com/science/article/pii/S1074761322001418
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Interferon-β acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation

2
1. scibot 11 Feb 2022
  
  in Public
  
  028256
  
  DOI: 10.1016/j.immuni.2022.01.011
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
2. scibot 11 Feb 2022
  
  in Public
  
  028256
  
  DOI: 10.1016/j.immuni.2022.01.011
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256
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RRID:IMSR_JAX:028256

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scibot

URL

sciencedirect.com/science/article/pii/S1074761322000401
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells

1
1. scibot 27 Jul 2021
  
  in Public
  
  RRID:IMSR_028256
  
  DOI: 10.1016/j.celrep.2019.08.086
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256 RRIDCUR:Unresolved RRIDCUR:SyntaxError
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Tags

RRIDCUR:Unresolved

RRIDCUR:SyntaxError

RRID:IMSR_JAX:028256

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719311489
www.sciencedirect.com www.sciencedirect.com

Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity

1
1. scibot 13 Jul 2021
  
  in Public
  
  028256
  
  DOI: 10.1016/j.cmet.2021.06.007
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:028256
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Tags

RRIDCUR:Missing

RRID:IMSR_JAX:028256

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413121002771
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

1
1. scibot 09 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:028256
  
  DOI: 10.1016/j.celrep.2020.01.099
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:028256

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720301339
www.sciencedirect.com www.sciencedirect.com

Inflammation-Induced Lactate Leads to Rapid Loss of Hepatic Tissue-Resident NK Cells

1
1. scibot 03 Sep 2020
  
  in Public
  
  IFNAR1fl/fl
  
  DOI: 10.1016/j.celrep.2020.107855
  
  Resource: (IMSR Cat# JAX_028256,RRID:IMSR_JAX:028256)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  Curator comments: B6(Cg)-Ifnar1tm1.1Ees/J Mus musculus IMSR Cat# JAX:028256
  
  What is this?
  
  RRID:IMSR_JAX:028256 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:028256

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scibot

URL

sciencedirect.com/science/article/pii/S2211124720308366
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability

1
1. scibot 08 Nov 2017
  
  in Public
  
  Mouse: B6.129S2-Ifnar1tm1Agt/MmjaxJackson LaboratoryStock# 028256
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:028256
  
  SciCrunch record: RRID:IMSR_JAX:028256
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:028256 RRIDCUR:Missing
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Tags

RRIDCUR:Missing

RRID:IMSR_JAX:028256

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S009286741730524X